Download or read book Total Synthesis of Spirastrellolide A Methyl Ester written by Jong Ho Lim and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Total Synthesis of spirastrellolide A Methyl Ester written by Philip James Maltas and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies Toward the Total Synthesis of Spirastrellolide A written by Steven Merwin Kennedy and published by . This book was released on 2010 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter one of this dissertation describes background into the biological properties of spirastrellolide A (SA) as a potent and selective protein phosphatase inhibitor. It then goes on to provide information on the isolation, structural elucidation, and structural features of SA. Additionally, it compares SA to other natural products with similar biological activity. Finally, chapter one ends with a literature review of synthetic work on SA and the other known spirastrellolides. By highlighting the total syntheses of spirastrellolide A methyl ester by Paterson and spirastrellolide F methyl ester by Fürstner an overview of synthetic challenges, strategies, and methods is seen. Other synthetic progress on the spirastrellolides is also briefly acknowledged. Chapter two provides a detailed account of my spirastrellolide A synthetic progress. It begins by analyzing synthetic challenges inherent to SA. Then my hypothesized synthetic plan for a total synthesis of SA is outlined. Synthetic advancement toward specific fragments of the SA carbon chain is discussed. It covers strategies employed for building the carbon framework of the molecule while installing necessary stereocenters. As chapter two continues, studies toward the synthesis of four distinct fragments of SA are explored. A synthesis of the C41-C47 side chain is explained. The C33-C40 fragment synthesis is also described. Next, the synthesis of stereospecific chlorohydrin containing molecules is examined. Finally, the progress toward a synthesis of the C1-C16 fragment is described in detail. The synthesis of this fragment focuses partially on the incorporation of methodology previously developed in the Chamberlin laboratory to install a cis-tetrahydropyran ring and an anti-1,3-diol moiety. The chapter concludes with suggested work. Chapter three provides all of the necessary information and data to repeat the work reported in chapter two. It begins with experimental procedures for synthesizing each of the key intermediates mentioned in successful synthetic routes. Each experimental procedure is followed by experimental data. Finally, chapter three is followed by an appendix with 1H and 13C NMR spectra useful for identifying key molecular structures.
Download or read book Heterocycles in Natural Product Synthesis written by Krishna C. Majumdar and published by John Wiley & Sons. This book was released on 2011-06-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Download or read book The Total Synthesis of Thailandamide A Methyl Ester written by Diane Jennifer Beylkin and published by . This book was released on 2015 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Naturally Occurring Organohalogen Compounds written by A. Douglas Kinghorn and published by Springer Nature. This book was released on 2023-07-24 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number — from fewer than 25 in 1968 — to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.
Download or read book Au Catalyzed Synthesis and Functionalization of Heterocycles written by Marco Bandini and published by Springer. This book was released on 2016-07-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal
Download or read book Total Synthesis of 7 8 epoxy 2 basmen 6 one and Pentalenolactone P Methyl Ester written by Ho-Jung Kang and published by . This book was released on 1991 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modern Alkyne Chemistry written by Barry M. Trost and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date overview of alkyne chemistry, taking into account the progress made over the last two decades. The experienced editors are renowned world leaders in the field, while the list of contributors reads like a "Who's Who" of synthetic organic chemistry. The result is a valuable reference not only for organic chemists at universities and in the chemical industry, but also for biologists and material scientists involved in the modern synthesis of organic compounds and materials.
Download or read book Studies Towards the Total Synthesis of spirastrellolide A written by Julien Genovino and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Heterocycles by Metathesis Reactions written by Joëlle Prunet and published by Springer. This book was released on 2016-11-26 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
Download or read book The Total Synthesis of Natural Products written by John ApSimon and published by Wiley-Interscience. This book was released on 2009-09-22 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Total Synthesis of Natural Products Edited by John ApSimon Volume Six The sixth volume in this popular series considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments and genes first reported during the period from 1972 through 1982 in this series. 1984 (0 471-09900-7) 291 pp. The Total Synthesis of Natural Products Edited by John ApSimon Volume Five In this fifth volume, ApSimon presents a review by Heathcock and co-workers covering the total synthesis in sesquiterpenes published during 1970-1979, offering an overview of current practice in synthesis. 1983 (0 471-09808-6) 550 pp. The Total Synthesis of Natural Products Edited by John ApSimon Volume Four The fourth volume in this successful series offers synthetic approaches to a wide variety of natural products, including the synthesis of cannabinoids, natural inophores, insect pheromones, monoterpenes, and prostaglandins. 1981 (0 471-05460-7) 610 pp. The Total Synthesis of Natural Products Edited by John ApSimon Volume Three 1977 (0 471-02392-2) 566 pp. The Total Synthesis of Natural Products Edited by John ApSimon Volume Two 1973 (0 471-03252-2) 754 pp. The Total Synthesis of Natural Products Edited by John ApSimon Volume One 1973 (0 471-03251-4) 603 pp.
Download or read book Boron Science written by Narayan S. Hosmane and published by CRC Press. This book was released on 2016-04-19 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: Boron has made a significant impact in our lives through its quiet use in fertilizers, fungicides, soaps, detergents, and heat-resistant glassware. Boron Science: New Technologies and Applications addresses the applications of boron in chemistry, industry, medicine, and pharmacology by explaining its role in problems such as catalysis and hydrobora
Download or read book Progress in Heterocyclic Chemistry written by Gordon Gribble and published by Elsevier. This book was released on 2010-10-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 22 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2009. * Covers the heterocyclic literature published in 2009 * Includes specialized reviews * Features contributions from leading researchers in their fields
Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content
Download or read book Total Synthesis of the Macrolide Core of spirastrellolide A written by S. M. Dalby and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemtracts written by and published by . This book was released on 2008 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
