Download or read book Topics in Statistical Inference for Treatment Effects written by Yang Jiang and published by . This book was released on 2017 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis unites three papers discussing different approaches for estimating treatment effects, either in observational study or randomized trial. The first paper presents an approach to sensitivity analysis for the instrumental variable (IV) method, which examines the sensitivity of inferences to violations of IV validity. Our approach is based on extending the Anderson-Rubin test and is robust to weak IVs. The second paper presents a unified R software ivmodel for analyzing instrumental variables with one endogenous variable. The package implements a general class of estimators, k-class estimators, and two confidence intervals that are fully robust to weak instruments. The package also provides power formulas. The sensitivity analysis discussed in the first paper is also included in the package. The third paper uses Hidden Markov Model to estimate the dynamic effects of lottery-based incentives towards patient's healthy behavior every day. The data is collected from randomized clinical trials.
Download or read book Statistical Inference as Severe Testing written by Deborah G. Mayo and published by Cambridge University Press. This book was released on 2018-09-20 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mounting failures of replication in social and biological sciences give a new urgency to critically appraising proposed reforms. This book pulls back the cover on disagreements between experts charged with restoring integrity to science. It denies two pervasive views of the role of probability in inference: to assign degrees of belief, and to control error rates in a long run. If statistical consumers are unaware of assumptions behind rival evidence reforms, they can't scrutinize the consequences that affect them (in personalized medicine, psychology, etc.). The book sets sail with a simple tool: if little has been done to rule out flaws in inferring a claim, then it has not passed a severe test. Many methods advocated by data experts do not stand up to severe scrutiny and are in tension with successful strategies for blocking or accounting for cherry picking and selective reporting. Through a series of excursions and exhibits, the philosophy and history of inductive inference come alive. Philosophical tools are put to work to solve problems about science and pseudoscience, induction and falsification.
Download or read book Developing a Protocol for Observational Comparative Effectiveness Research A User s Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
Download or read book Fundamentals of Statistical Inference written by Norbert Hirschauer and published by Springer Nature. This book was released on 2022-08-18 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a coherent description of foundational matters concerning statistical inference and shows how statistics can help us make inductive inferences about a broader context, based only on a limited dataset such as a random sample drawn from a larger population. By relating those basics to the methodological debate about inferential errors associated with p-values and statistical significance testing, readers are provided with a clear grasp of what statistical inference presupposes, and what it can and cannot do. To facilitate intuition, the representations throughout the book are as non-technical as possible. The central inspiration behind the text comes from the scientific debate about good statistical practices and the replication crisis. Calls for statistical reform include an unprecedented methodological warning from the American Statistical Association in 2016, a special issue “Statistical Inference in the 21st Century: A World Beyond p 0.05” of iThe American StatisticianNature in 2019. The book elucidates the probabilistic foundations and the potential of sample-based inferences, including random data generation, effect size estimation, and the assessment of estimation uncertainty caused by random error. Based on a thorough understanding of those basics, it then describes the p-value concept and the null-hypothesis-significance-testing ritual, and finally points out the ensuing inferential errors. This provides readers with the competence to avoid ill-guided statistical routines and misinterpretations of statistical quantities in the future. Intended for readers with an interest in understanding the role of statistical inference, the book provides a prudent assessment of the knowledge gain that can be obtained from a particular set of data under consideration of the uncertainty caused by random error. More particularly, it offers an accessible resource for graduate students as well as statistical practitioners who have a basic knowledge of statistics. Last but not least, it is aimed at scientists with a genuine methodological interest in the above-mentioned reform debate.
Download or read book Statistical Inference written by Michael W. Oakes and published by . This book was released on 1990 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Statistical Inference written by Eugene S. Edgington and published by New York : Toronto : McGraw-Hill. This book was released on 1969 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Probability and Statistical Inference written by Miltiadis C. Mavrakakis and published by CRC Press. This book was released on 2021-03-28 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability and Statistical Inference: From Basic Principles to Advanced Models covers aspects of probability, distribution theory, and inference that are fundamental to a proper understanding of data analysis and statistical modelling. It presents these topics in an accessible manner without sacrificing mathematical rigour, bridging the gap between the many excellent introductory books and the more advanced, graduate-level texts. The book introduces and explores techniques that are relevant to modern practitioners, while being respectful to the history of statistical inference. It seeks to provide a thorough grounding in both the theory and application of statistics, with even the more abstract parts placed in the context of a practical setting. Features: •Complete introduction to mathematical probability, random variables, and distribution theory. •Concise but broad account of statistical modelling, covering topics such as generalised linear models, survival analysis, time series, and random processes. •Extensive discussion of the key concepts in classical statistics (point estimation, interval estimation, hypothesis testing) and the main techniques in likelihood-based inference. •Detailed introduction to Bayesian statistics and associated topics. •Practical illustration of some of the main computational methods used in modern statistical inference (simulation, boostrap, MCMC). This book is for students who have already completed a first course in probability and statistics, and now wish to deepen and broaden their understanding of the subject. It can serve as a foundation for advanced undergraduate or postgraduate courses. Our aim is to challenge and excite the more mathematically able students, while providing explanations of statistical concepts that are more detailed and approachable than those in advanced texts. This book is also useful for data scientists, researchers, and other applied practitioners who want to understand the theory behind the statistical methods used in their fields.
Download or read book Dynamic Treatment Regimes written by Anastasios A. Tsiatis and published by CRC Press. This book was released on 2019-12-19 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment option he or she should receive. Thus, a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine, which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime, one that, if used to select treatments for the patient population, would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www.dtr-book.com includes updates, corrections, new papers, and links to useful websites.
Download or read book Topics in Theoretical and Applied Statistics written by Giorgio Alleva and published by Springer. This book was released on 2016-05-19 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest research findings from the 46th International Meeting of the Italian Statistical Society (SIS) in Rome, during which both methodological and applied statistical research was discussed. This selection of fully peer-reviewed papers, originally presented at the meeting, addresses a broad range of topics, including the theory of statistical inference; data mining and multivariate statistical analysis; survey methodologies; analysis of social, demographic and health data; and economic statistics and econometrics.
Download or read book Causal Inference in Statistics Social and Biomedical Sciences written by Guido W. Imbens and published by Cambridge University Press. This book was released on 2015-04-06 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents statistical methods for studying causal effects and discusses how readers can assess such effects in simple randomized experiments.
Download or read book Statistical Inference for the Treatment Effect in Cancer Clinical Trials written by Shan Jiang and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Statistical Inference written by D. R. Cox and published by Cambridge University Press. This book was released on 2006-08-10 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this definitive book, D. R. Cox gives a comprehensive and balanced appraisal of statistical inference. He develops the key concepts, describing and comparing the main ideas and controversies over foundational issues that have been keenly argued for more than two-hundred years. Continuing a sixty-year career of major contributions to statistical thought, no one is better placed to give this much-needed account of the field. An appendix gives a more personal assessment of the merits of different ideas. The content ranges from the traditional to the contemporary. While specific applications are not treated, the book is strongly motivated by applications across the sciences and associated technologies. The mathematics is kept as elementary as feasible, though previous knowledge of statistics is assumed. The book will be valued by every user or student of statistics who is serious about understanding the uncertainty inherent in conclusions from statistical analyses.
Download or read book Topics in Biostatistics written by Walter T. Ambrosius and published by Springer Science & Business Media. This book was released on 2007-07-06 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. It introduces advanced methods in statistics, including how to choose and work with statistical packages. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. The book is an essential resource for researchers at every level of their career.
Download or read book All of Statistics written by Larry Wasserman and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taken literally, the title "All of Statistics" is an exaggeration. But in spirit, the title is apt, as the book does cover a much broader range of topics than a typical introductory book on mathematical statistics. This book is for people who want to learn probability and statistics quickly. It is suitable for graduate or advanced undergraduate students in computer science, mathematics, statistics, and related disciplines. The book includes modern topics like non-parametric curve estimation, bootstrapping, and classification, topics that are usually relegated to follow-up courses. The reader is presumed to know calculus and a little linear algebra. No previous knowledge of probability and statistics is required. Statistics, data mining, and machine learning are all concerned with collecting and analysing data.
Download or read book Causal Inference in Statistics written by Judea Pearl and published by John Wiley & Sons. This book was released on 2016-01-25 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: CAUSAL INFERENCE IN STATISTICS A Primer Causality is central to the understanding and use of data. Without an understanding of cause–effect relationships, we cannot use data to answer questions as basic as "Does this treatment harm or help patients?" But though hundreds of introductory texts are available on statistical methods of data analysis, until now, no beginner-level book has been written about the exploding arsenal of methods that can tease causal information from data. Causal Inference in Statistics fills that gap. Using simple examples and plain language, the book lays out how to define causal parameters; the assumptions necessary to estimate causal parameters in a variety of situations; how to express those assumptions mathematically; whether those assumptions have testable implications; how to predict the effects of interventions; and how to reason counterfactually. These are the foundational tools that any student of statistics needs to acquire in order to use statistical methods to answer causal questions of interest. This book is accessible to anyone with an interest in interpreting data, from undergraduates, professors, researchers, or to the interested layperson. Examples are drawn from a wide variety of fields, including medicine, public policy, and law; a brief introduction to probability and statistics is provided for the uninitiated; and each chapter comes with study questions to reinforce the readers understanding.
Download or read book Current Issues in Statistical Inference written by Dev Basu and published by IMS. This book was released on 1992 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regression Modeling Strategies written by Frank E. Harrell and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many texts are excellent sources of knowledge about individual statistical tools, but the art of data analysis is about choosing and using multiple tools. Instead of presenting isolated techniques, this text emphasizes problem solving strategies that address the many issues arising when developing multivariable models using real data and not standard textbook examples. It includes imputation methods for dealing with missing data effectively, methods for dealing with nonlinear relationships and for making the estimation of transformations a formal part of the modeling process, methods for dealing with "too many variables to analyze and not enough observations," and powerful model validation techniques based on the bootstrap. This text realistically deals with model uncertainty and its effects on inference to achieve "safe data mining".
