Download or read book Tini s Tangles written by Shelly Winsor Calcagno and published by . This book was released on 2012-07 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Things get a little hairy for Tini after a day of rickety-rackety hair-brushing drama! Shelly Calcagno is a freelance writer who lives in Waterdown, Ontario, with her amazing husband, two energetic kids, and a cranky cat named Zoe. www.shellycalcagno.com
Download or read book Experimental and Clinical Neuropathology written by Kurt Jellinger and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Death of Expertise written by Tom Nichols and published by Oxford University Press. This book was released on 2024 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In the early 1990s, a small group of "AIDS denialists," including a University of California professor named Peter Duesberg, argued against virtually the entire medical establishment's consensus that the human immunodeficiency virus (HIV) was the cause of Acquired Immune Deficiency Syndrome. Science thrives on such counterintuitive challenges, but there was no evidence for Duesberg's beliefs, which turned out to be baseless. Once researchers found HIV, doctors and public health officials were able to save countless lives through measures aimed at preventing its transmission"--
Download or read book Assassinistas written by Tini Howard and published by National Geographic Books. This book was released on 2018-08-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Family. Retro Sass. Highly Trained--To Kick Your Ass! Take a semester off with Dominic Price, his mom, his boyfriend, and $40,000 of black-market weapons. What could possibly go wrong? First there were three: Octavia, Charlotte, and Rosalyn, a trio of badass hit-women who picked up the slack when the going got too real for other so-called top-level assassins. But things happened. Octavia hung up her semi-automatic for a semi-lucrative kidnapping insurance scam. Charlotte chose an expensive Chardonnay, love, marriage and, until recently, a baby carriage. And Rosalyn? There's a lot of conspiracies, but according to the federal government, she's simply M.I.A. When a kidnapping hits too close to home, Octavia is forced out of retirement and back into the bounty-hunting business. Down two partners, she recruits her son Dominic and his boyfriend Taylor to aid and abet her in a semester of murder-based work study, where she'll teach them everything she knows (if she can get them to put down the video games, stop making out, and actually focus on the mission already). Can this dysfunctional modern family pull off the greatest mission in the history of the ASSASSINISTAS? Collects the complete miniseries, issues #1-6.
Download or read book Drosophila A Toolbox for the Study of Neurodegenerative Disease written by Amritpal Mudher and published by Taylor & Francis. This book was released on 2020-11-25 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drosophila gives an overview of the ways in which Drosophila is currently being used as a model organism to further our understanding of a spectrum of human neurological diseases. Each chapter is written by respected researchers and gives an excellent account of the subject that is suitable for postgraduate and postdoctoral researchers.
Download or read book Disney Lilo and Stitch Tiny Book written by Brooke Vitale and published by Insight Editions. This book was released on 2021-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relive the magic of Disney’s beloved 2002 film Lilo & Stitch with this collectible tiny book featuring story art from the film. One of Disney’s animated favorites, Lilo & Stitch instantly charmed audiences with its story of family and friendship, exciting animation, and enchanting characters. Now, fans can keep Lilo and her spunky pal Stitch close to their hearts with this tiny storybook retelling of the iconic film, illustrated with art and imagery pulled straight from the screen. Part of Insight’s ongoing series of miniature storybooks based on popular Disney films, this tiny book is a unique collector’s item that Disney fans will treasure for years to come.
Download or read book The Tablet written by and published by . This book was released on 1904 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Invisible Child written by Andrea Elliott and published by Random House. This book was released on 2021-10-05 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: PULITZER PRIZE WINNER • A “vivid and devastating” (The New York Times) portrait of an indomitable girl—from acclaimed journalist Andrea Elliott “From its first indelible pages to its rich and startling conclusion, Invisible Child had me, by turns, stricken, inspired, outraged, illuminated, in tears, and hungering for reimmersion in its Dickensian depths.”—Ayad Akhtar, author of Homeland Elegies ONE OF THE TEN BEST BOOKS OF THE YEAR: The New York Times • ONE OF THE BEST BOOKS OF THE YEAR: The Atlantic, The New York Times Book Review, Time, NPR, Library Journal In Invisible Child, Pulitzer Prize winner Andrea Elliott follows eight dramatic years in the life of Dasani, a girl whose imagination is as soaring as the skyscrapers near her Brooklyn shelter. In this sweeping narrative, Elliott weaves the story of Dasani’s childhood with the history of her ancestors, tracing their passage from slavery to the Great Migration north. As Dasani comes of age, New York City’s homeless crisis has exploded, deepening the chasm between rich and poor. She must guide her siblings through a world riddled by hunger, violence, racism, drug addiction, and the threat of foster care. Out on the street, Dasani becomes a fierce fighter “to protect those who I love.” When she finally escapes city life to enroll in a boarding school, she faces an impossible question: What if leaving poverty means abandoning your family, and yourself? A work of luminous and riveting prose, Elliott’s Invisible Child reads like a page-turning novel. It is an astonishing story about the power of resilience, the importance of family and the cost of inequality—told through the crucible of one remarkable girl. Winner of the J. Anthony Lukas Book Prize • Finalist for the Bernstein Award and the PEN/John Kenneth Galbraith Award
Download or read book Vampire The Masquerade Vol 1 written by Tim Seeley and published by Vault Comics. This book was released on 2021-03-23 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global bestseller Vampire: The Masquerade comes to comics in Vampire: The Masquerade Vol. 1: Winter's Teeth. When Camarilla enforcer Cecily Bain takes a fledgling vampire under her wing, she's dragged into a vast conspiracy that will topple princes and threaten the very Masquerade. BORN FROM THE WORLD OF THE INTERNATIONALLY BEST-SELLING ROLE PLAYING GAME, VAMPIRE: THE MASQUERADE'S CRITICALLY ACCLAIMED COMICS DEBUT SPINS A GRIPPING AND TRAGIC TALE ABOUT THE BEAST WITHIN US ALL. When Cecily Bain, an enforcer for the Twin Cities' vampiric elite, takes a mysterious new vampire under her wing, she's dragged into an insidious conspiracy. Meanwhile, on the outskirts of the cities, a rebellious found-family of vampire cast-outs investigates a vicious killing. As the unlives of the Kindred twine together and betrayals are unearthed, will Cecily be able to escape and save what's left of her family, or will she be yet another pawn sacrificed to maintain the age-old secret: that vampires exist among the living? Vampire: The Masquerade Vol. 1: Winter's Teeth collects issues #1 - #5 of the ongoing series. Read more in Vampire: The Masquerade Vol. 2: The Mortician's Army, collecting issues #6 - #10 of the series For fans of VAMPIRE: The Masquerade RPG, WEREWOLF: The Apocalypse RPG, The World of Darkness, American Vampire, Killadelphia, Something is Killing the Children, Interview with the Vampire, The Vampire Lestat/The Vampire Chronicles, Sookie Stackhouse/Southern Vampire Mysteries/True Blood, Certain Dark Things, Underworld, and vampire/werewolf/monster graphic novels, tabletop/RPGs, books, movies, video games, and series! “This is a fresh take on vampires, mixing it with crime, thrillers, and a pinch of romance all with a vein of horror running through it.” -- Horror DNA “… strongly recommend this book to both fans of the franchise and newcomers.” – Grimdark Magazine "I’m absolutely in love with what a badass Cecily is..." - The Wandering Nerd Girl “Vampire: the Masquerade … is an enjoyable read even if you’re not familiar with the RPG… like the real world, but with hotter outfits, blood, and fangs. – Graphic Policy “This is the horror thriller we all need.” – Horror DNA
Download or read book Neuronal Degeneration and Regeneration From Basic Mechanisms to Prospects for Therapy written by F.W. Van Leeuwen and published by Elsevier. This book was released on 1998-11-09 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Academy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases. The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries.
Download or read book The Century Illustrated Monthly Magazine written by Josiah Gilbert Holland and published by . This book was released on 1894 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scribner s Monthly written by and published by . This book was released on 1894 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book WebGL Programming Guide written by Kouichi Matsuda and published by Addison-Wesley. This book was released on 2013-07-04 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using WebGL®, you can create sophisticated interactive 3D graphics inside web browsers, without plug-ins. WebGL makes it possible to build a new generation of 3D web games, user interfaces, and information visualization solutions that will run on any standard web browser, and on PCs, smartphones, tablets, game consoles, or other devices. WebGL Programming Guide will help you get started quickly with interactive WebGL 3D programming, even if you have no prior knowledge of HTML5, JavaScript, 3D graphics, mathematics, or OpenGL. You’ll learn step-by-step, through realistic examples, building your skills as you move from simple to complex solutions for building visually appealing web pages and 3D applications with WebGL. Media, 3D graphics, and WebGL pioneers Dr. Kouichi Matsuda and Dr. Rodger Lea offer easy-to-understand tutorials on key aspects of WebGL, plus 100 downloadable sample programs, each demonstrating a specific WebGL topic. You’ll move from basic techniques such as rendering, animating, and texturing triangles, all the way to advanced techniques such as fogging, shadowing, shader switching, and displaying 3D models generated by Blender or other authoring tools. This book won’t just teach you WebGL best practices, it will give you a library of code to jumpstart your own projects. Coverage includes: • WebGL’s origin, core concepts, features, advantages, and integration with other web standards • How and basic WebGL functions work together to deliver 3D graphics • Shader development with OpenGL ES Shading Language (GLSL ES) • 3D scene drawing: representing user views, controlling space volume, clipping, object creation, and perspective • Achieving greater realism through lighting and hierarchical objects • Advanced techniques: object manipulation, heads-up displays, alpha blending, shader switching, and more • Valuable reference appendixes covering key issues ranging from coordinate systems to matrices and shader loading to web browser settings This is the newest text in the OpenGL Technical Library, Addison-Wesley’s definitive collection of programming guides an reference manuals for OpenGL and its related technologies. The Library enables programmers to gain a practical understanding of OpenGL and the other Khronos application-programming libraries including OpenGL ES and OpenCL. All of the technologies in the OpenGL Technical Library evolve under the auspices of the Khronos Group, the industry consortium guiding the evolution of modern, open-standards media APIs.
Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.
Download or read book The Cigarette Century written by Allan M. Brandt and published by Basic Books. This book was released on 2009-01-06 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: The invention of mass marketing led to cigarettes being emblazoned in advertising and film, deeply tied to modern notions of glamour and sex appeal. It is hard to find a photo of Humphrey Bogart or Lauren Bacall without a cigarette. No product has been so heavily promoted or has become so deeply entrenched in American consciousness. And no product has received such sustained scientific scrutiny. The development of new medical knowledge demonstrating the dire harms of smoking ultimately shaped the evolution of evidence-based medicine. In response, the tobacco industry engineered a campaign of scientific disinformation seeking to delay, disrupt, and suppress these studies. Using a massive archive of previously secret documents, historian Allan Brandt shows how the industry pioneered these campaigns, particularly using special interest lobbying and largesse to elude regulation. But even as the cultural dominance of the cigarette has waned and consumption has fallen dramatically in the U.S., Big Tobacco remains securely positioned to expand into new global markets. The implications for the future are vast: 100 million people died of smoking-related diseases in the 20th century; in the next 100 years, we expect 1 billion deaths worldwide.
Download or read book Star Wars Thrawn Ascendancy Book II Greater Good written by Timothy Zahn and published by Random House Worlds. This book was released on 2021-04-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • Thrawn and his allies race to save the Chiss Ascendancy from an unseen enemy in the second book in the epic Star Wars: Thrawn Ascendancy trilogy from bestselling author Timothy Zahn. Thrawn’s latest triumph still rests newly on his shoulders. He has led the Chiss to victory and brought glory to the House of Mitth, but the true threat to the Ascendancy has not yet been extinguished. Their foes do not send threats or ultimatums, do not mass ships on the edge of the Chaos. Their weapons come cloaked in smiles and generosity: Gifts offered freely. Services granted unconditionally. Across the Ascendancy, seemingly inconsequential events could herald the doom of the Chiss. As Thrawn and the Expansionary Defense Fleet rally to uncover the plot, they discover a chilling truth: Rather than invade Chiss capitals or pillage resources, their enemy strikes at the very foundation of the Ascendancy, seeking to widen the rifts between the Nine Ruling Families and the Forty Great Houses below. As rivalry and suspicion sow discord among allies, each warrior must decide what matters most to them: the security of their family or the survival of the Ascendancy itself.
