Download or read book Thyroid Hormone induced Actin Gene Expression During Postembryonic Development in Rana Catesbeiana microform written by Li Zheng and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 2001 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amphibian metamorphosis involves a complex but coordinate transformation of individual tissues in a tadpole. It is becoming increasingly clear that thyroid hormone controls metamorphosis by regulating a cascade of gene expression in this process. Thus, the overall objective of my thesis was to establish whether or not thyroid hormone induces the expression of one or more of the actin genes in the heart or other tissues/organs of the metamorphosing Rana catesbeiana (American bullfrog) tadpole. In order to accomplish my objective, I isolated and characterized the cDNAs and genomic DNAs encoding various isoforms of actin in this amphibian and, subsequently, evaluated the expression of the genes encoding these actin isoforms.

Download or read book Cell and Molecular Biology of the Ear written by David J. Lim and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Howard House, founder of the House Ear Institute and House Ear Clinic often uses the analogy of planting a seed when referring to establishing the House Ear Institute in 1946. Two grateful patients of Dr. House put forth the idea that his knowledge and innovative skills could be used to expand the understanding of hearing impairment and its treatment. Those two early patients provided the "seed money" to begin the Institute. Since that time, the growth has been phenomenal from a one-man laboratory to a multidisciplinary facility boasting over 175 scien tists, physicians, and support staff, all dedicated to the advancement of otologic research and education. Six years ago after a half-century of remarkable success with prosthetic and device research, the Institute began cultivating a new field of endeavor-cell and molecular biology. Don Nielsen, then the Institute's Executive Vice President for Research and Scientific Director, began exploring the potential for hair cell regen eration and presented his ideas to the Board of Trustees. For a period of six months, we did a lot of fact finding to assess what role the Institute might take in this excit ing new field.