Download or read book Thermal Acclimation Cardiac Performance and Adrenergic Sensitivity in Rainbow Trout Oncorhynchus Mykiss microform written by John Ellis Keen and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1992 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Influence of Adrenergic Stimulation and Coronary Blood Flow on in Vivo Cardiac Performance in Rainbow Trout Oncorhynchus Mykiss microform written by Anthony Kurt Gamperl and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of Thermal Acclimation on the Functional Properties of the Trout Myocardium written by Jordan Mitchell Klaiman and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Rainbow trout (Oncorhynchus mykiss) remain active in waters that range between 4oC - 20oC. These large changes in temperature can represent a significant challenge to maintaining physiological processes, including cardiac function. Previous studies have demonstrated that there are mechanisms of thermal compensation in the heart following acclimation to the extremes of the trout's temperature range. However, little is known of the function of the cardiac myofilaments during this response. The objective of this thesis was to examine how thermal acclimation affects the function and composition of the trout myocardium and of the contractile element. I found that when tested at common temperatures, cold acclimation caused a 50% increase in the maximal rate of cardiac actomyosin Mg2+-ATPase, an increase in the Ca2+ sensitivity of skinned cardiac trabeculae, and an increase in the developed pressure and contractility of the intact heart. To investigate the mechanistic basis for these changes in function, I examined the contractile proteins for changes in the phosphorylation state and for differential isoform expression. As well, I characterized changes in the morphology of the trout heart. I found that a 50% decrease in the phosphorylation state of cardiac troponin T, and subtle reductions in the phosphorylation state of slow skeletal troponin T and myosin binding protein-C were associated with these changes in function. In addition, there were multiple isoforms of troponin I (TnI) and troponin T (TnT) expressed in the adult trout heart. However, the expression of the TnT isoforms did not change with thermal acclimation and changes in expression pattern of TnI isoforms could not be determined. Lastly, I found that cold acclimation did not always result in cardiac hypertrophy. When the hypertrophic response was observed, it was predominantly found in males and was accompanied by an increase in collagen content. There was, however, a consistent decrease in the compact layer thickness in both males and females following cold acclimation. The decrease in the compact layer thickness following cold acclimation correlated with increased functional properties of the ventricle. Together, these remodeling events result in improved cardiac function, which helps to explain how the trout heart is able to remain functional at low temperatures.
Download or read book Influence of Adrenergic Stimulation and Coronary Blood Flow on in Vivo Cardiac Performance in Rainbow Trout Oncorhynchus Mykiss written by Anthony Kurt Gamperl and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardio Respiratory Control in Vertebrates written by Mogens L. Glass and published by Springer Science & Business Media. This book was released on 2009-07-24 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hopefully, this book will be taken off of the shelf frequently to be studied carefully over many years. More than 40 researchers were involved in this project, which examines respiration, circulation, and metabolism from ?sh to the land vertebrates, including human beings. A breathable and stable atmosphere ?rst appeared about 500 million years ago. Oxygen levels are not stable in aquatic environments and exclusively water-breathing ?sh must still cope with the ever-changing levels of O 2 and with large temperature changes. This is re?ected in their sophisticated count- current systems, with high O extraction and internal and external O receptors. 2 2 The conquest for the terrestrial environment took place in the late Devonian period (355–359 million years ago), and recent discoveries portray the gradual transitional evolution of land vertebrates. The oxygen-rich and relatively stable atmospheric conditionsimpliedthatoxygen-sensingmechanismswererelativelysimpleandl- gain compared with acid–base regulation. Recently, physiology has expanded into related ?elds such as biochemistry, molecular biology, morphology and anatomy. In the light of the work in these ?elds, the introduction of DNA-based cladograms, which can be used to evaluate the likelihood of land vertebrates and lung?sh as a sister group, could explain why their cardio-respiratory control systems are similar. The diffusing capacity of a duck lung is 40 times higher than that of a toad or lung?sh. Certainly, some animals have evolved to rich high-performance levels.
Download or read book Acupuncture Therapy for Neurological Diseases written by Ying Xia and published by Springer Science & Business Media. This book was released on 2010-09-08 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acupuncture therapy has been practiced in China and other Asian countries for more than two thousand years. Modern clinical research has confirmed the impressive therapeutic effect of acupuncture on numerous human ailments, such as controlling pain, nausea, and vomiting. However, the biological mechanisms of acupuncture are still under debate. In Traditional Chinese Medicine (TCM), the mechanism of acupuncture therapy is explained by a meridian model. According to this model, acupuncture is believed to treat the diseased organs by modulating two conditions known as Yin and Yang, which represent all the opposite principles that people find in the universe, both inside and outside the human body. Yin and Yang complement each other, and are subjected to changes between each other. The balance of Yin and Yang is thought to be maintained by Qi, an energy substance flowing constantly through the meridian, a network connecting all the organs of the body. The illness, according to this theory, is the temporary dominance of one principle over the other, owing to the blockade of the Qi from flowing through the meridian under certain circumstance. The axiom of “No stagnation, No pain” in TCM summarizes this concept. Thus, the goal of acupuncture treatment is to restore the balance of Yin and Yang conditions in the diseased organ(s). This theory has been considered to be useful to guide this ancient therapy, such as carrying out diagnosis, deciding on the principle, and selecting the acupoints.
Download or read book Toxicology in Transition written by Gisela H. Degen and published by Springer. This book was released on 2011-12-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume contains the main papers presented at the 1994 EUROTOX Congress, Basel, Switzerland, August 21-24, 1994. Toxicology has become a less descriptive science because more importance has been placed on the mechanisms underlying toxic effects. This is reflected in symposia and workshops devoted to species differences in organ toxicity, receptor-mediated toxicity and stereochemical effects of xenobiotics. Recent progress in the fields of immunotoxicology, ecotoxicology, and neurotoxicology is highlighted and documented together with the present discussion on harmonized regulatory guidelines.
Download or read book Antifouling Compounds written by Nobuhiro Fusetani and published by Springer Science & Business Media. This book was released on 2006-10-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awareness of the dangers of toxic components in antifouling coatings has raised interest in the potential for nontoxic alternatives. Marine organisms from bacteria to invertebrates and plants use chemicals to communicate and defend themselves. This book explores natural based antifoulants, their ecological functions, methods of characterisation and possible uses in antifouling. The text takes on the challenge of identifying such compounds, designing sustainable production and incorporating them into antifouling coatings.
Download or read book Endocrines and Osmoregulation written by P.J. Bentley and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a review of the previous edition: "I strongly recommend it as an essential reading and reference book for younger and older workers alike". Nature
Download or read book Comparative and Veterinary Pharmacology written by Fiona Cunningham and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human–animal bond has evolved and diversi?ed down the ages. Dogs, cats and even horses, have long ful?lled the role of faithful companion and indeed, as exempli?ed by the introduction of seeing and hearing dogs, there may be a critical level of co-dependency between the species. In the twenty-?rst century, the animal types that are kept as pets in many parts of the world are extensive ranging from reptiles through rodents to ruminants and beyond. As would be predicted by the nature of the relationship, the approach to treatment of a companion animal is often closely aligned to that which would have been offered to their owner. However, an increasing awareness of welfare issues, such as the recognition that animals expe- ence pain and the proven bene?ts of disease prevention in intensive farming units, together with the growth in zoos and wildlife parks, has increased the likelihood of food producing and non-domesticated animals receiving medicinal products during their life-time. Although many of the individual drugs or classes of drugs administered to animals are the same as, or derived from, those given to man, the safe and effective use of drugs in animals often cannot be achieved by simply transposing knowledge of drug action on, or behaviour in, the body from one species to another. The impact of the anatomical, physiological and pathophysiological variability that spans the animal kingdom can often profoundly alter drug response.
Download or read book Osmoregulation in Birds written by E. Skadhauge and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach of this treatise is physiological throughout. In the eyes of the author it answers the rhetorical question raised by Maurice B. Visscher at the Physiology Congress in Washington D. C. in 1968: Does physiology exist? What he meant by this question was whether the fields of cellular physiology and physiology of the various organ systems had become so large that physiology as such had vanished. The firm answer is that physiology does indeed exist. Although it is important to study physiological problems at the subcellular level, it is importan- and equally difficult - to study organ regulation at the cellular level, organ interaction, and integration into the whole organism. An account of avian osmoregulation from an integrated point of view is attempted in this book. Since reading Homer W. Smith's From Fish to Philosopher and August Krogh's Osmoregulation in Aquatic Animals verte brate osmoregulation has been in the center of the author's interest. The focus was set on avian osmoregulation after personal contact with the School of Krogh when working in the laboratory of Bodil M. Schmidt-Nielsen. The fundamental concepts and isotope techniques introduced by Hans H. Ussing have been of constant inspiration. An excellent example for the study of osmoregulation at the cellular level was given by the late Jean Maetz. The writing of this book was suggested by Donald S. Farner who is thanked for thorough editorial assistance, and especially with help in the subtle semantic peculiarities of the English language.
Download or read book Circannual Rhythms written by Eberhard Gwinner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to the more or less static properties of the environ ment, plants and animals must cope with its temporal variations. Among the most conspicuous temporal changes to which organisms are exposed are periodic phenomena generated by the rotation of the earth about its axis, its revolution around the sun, and the more complex movements of the moon in relation to both sun and earth. The first two of these astronomical cycles are basic to the familiar daily and annual rhythms, respectively, in the environment. The third generates somewhat more complex cycles, such as those in moonlight and variations in tides. These environmental cycles have provided challenges and opportunities for organisms to adjust their physiology and behavior to them. Indeed, the predictability inherent to these periodic processes has enabled organisms to evolve innate endogenous rhythmic programs that match the environmental cycles and allow, in a variety of different ways, adjustment of biological activities to the cycles of environmental changes. The endogenous nature of rhythmicity was first clearly recognized in the 1930's in daily periodicities, the most widely distributed and best investigated class of biological rhythms of this type. In the 1950's, demonstrations of endogenous tidal and lunar rhythms, which occur in some littoral and marine organisms, ensued. Another decade passed before endogenous annual periodicities were first demonstrated unambiguously.
Download or read book Fate of Pharmaceuticals in the Environment and in Water Treatment Systems written by Diana S. Aga and published by CRC Press. This book was released on 2007-12-26 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection of pharmaceutical residues remained elusive until instruments such as liquid chromatography and mass spectrometry became commonplace in environmental laboratories. The documentation of the occurrence of pharmaceutical residues and endocrine disrupting chemicals in water resources has raused questions about their long-term effects
Download or read book Water Balance in Land Arthropods written by E. B. Edney and published by Springer. This book was released on 2012-02-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Writers on arthropod water relationships range from bio physicists and biochemists to population ecologists-a fact that gives cause to wonder whether the field is already too heterogeneous to be written about in a single book by a single author. I have partly avoided the problem by concentrating largely on physiological mechanisms and by omitting most aspects of behavioural regulation and most aspects of heat balance and body temperature, except when these impinge directly on water balance. Even within this limited field there has been a lot of work during the past twenty years, as a result of which some problems have been solved (or at least more clearly defined), and many others have been opened up. On the whole there has been a welcome change to a more rigorous experimental approach and it is now possible for water balance people to state their problems in physiological terms. Good progress has been made towards understanding the mechanisms involved in nearly all avenues of water uptake and loss, although problems indeed remain. The cuticle has yielded part of its secrets to electron micrography, but ex ploration by means oflipid biochemistry among other techniques is necessary for a real understanding of cuticle permeability.
Download or read book The Ethology of Predation written by E. Curio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Predation is an ecological factor of almost universal importance for the biol ogist who aims at an understanding of the habits and structures of animals. Despite its pervasive nature opinions differ as to what predation really is. So far it has been defined only in negative terms; it is thought not to be par asitism, the other great process by which one organism harms another, nor filter-feeding, carrion-eating, or browsing. Accordingly, one could define predation as a process by which an animal spends some effort to locate a live prey and, in addition, spends another effort to mutilate or kill it. Ac cording to this usage of the word a nudibranch, for example, that feeds on hydroids would be a predator inasmuch as it needs some time to locate col onies of its prey which, after being located, scarcely demand more than eating, which differs little from browsing. From the definition just proposed consumption of the prey following its capture has been intentionally omit ted. Indeed, an animal may be disposed of without being eaten. Hence the biological significance of predation may be more than to maintain nutrition al homeostasis. In fact, predation may have something in common with the more direct forms of competition, a facet that will be only cursorily touched upon in this book.
Download or read book Green and Sustainable Pharmacy written by Klaus Kümmerer and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kümmerer, K. editor: Pharmaceuticals in the Environment). At the same time the issue of sustainable chemistry gained momentum. Bringing both together would result in sustainable pharmacy. Sustainable pharmacy is a totally new issue and approach. It addresses environmental, economical and social aspects of pharmacy. In the present stage the focus will be on environmental issues along the whole lifecycle of a pharmaceutical entity. That is dealing with resources and energy input but also with waste issues for example during the synthesis and production of an active pharmaceutical ingredient. Furthermore, it would also look on the compounds themselves and will aim to improve the degradability of the compounds after their use in the environment to reduce the environmental risk caused by pharmaceuticals in the environment. Another issue is the people using pharmaceuticals such as pharmacists, medical doctors and patients. How can they contribute to more efficient use of pharmaceuticals with less environmental burden and less risk for drinking water. The book "Sustainable Pharmacy" will address all these issues and will be the first one dealing with this important topic.
Download or read book Vertebrate Red Blood Cells written by Mikko Nikinmaa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the respiratory function of vertebrate red cells. I have defined the phrase "respiratory function" broadly to include, in addition to the actual oxygen and carbon dioxide transport, erythropoiesis, haemoglobin synthesis, red cell structure, the deformability of red cells in circulation, ion and substrate transport across the cell membrane, cellular metabolism, and control of cellular volume and pH. All of these aspects of the red cell function may affect gas transport between the respiratory epithelia and the tissues. Throughout the book, I have tried to relate our current knowledge about the nucleated red cell function to the wealth of information about the function of mammalian red cells. However, whenever possible, I have placed the emphasis on the nucleated red cell function for two reasons. First, the erythro cytes of 90% of vertebrate species are nucleated, and, second, nucleated red cell function has not been reviewed earlier in a single volume. This being the case, I have tried to make the reference list as complete as I could with regard to nucleated red cells. I hope that the approach adopted is useful for both com parative and human physiologists. Many people have contributed to the making of this book directly or in directly. Antti Soivio started me in this field. Prof. Henrik Wallgren has always encouraged fresh scientific ideas in his department. My present ideas of red cell function have been influenced by work carried out with Prof. Roy E.
