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Book Therapeutic Effect of 4 Oral Hypoglycemic Agent in Patients with Type 2 Diabetes Mellitus who Have Limitation to Insulin

Download or read book Therapeutic Effect of 4 Oral Hypoglycemic Agent in Patients with Type 2 Diabetes Mellitus who Have Limitation to Insulin written by Yoo Won Sang and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Aim : The purpose of this study was to evaluate the clinical efficacy of four oral hypoglycemic agents combination therapy (4-OHA) in patients with poorly controlled type 2 diabetes mellitus (T2DM) who cannot accept insulin therapy.Methods : Forty-seven patients with T2DM were enrolled according to the following criteria: 1) HbA1c > 8.5% (69 mmol/mol); 2) ongoing treatment with 3-OHA combination (metformin, sulfonylurea, and dipeptidyl peptidase-4 inhibitor); 3) limitations for the application of insulin therapy. The patients were administered the fourth OHA (pioglitazone) in addition to the previous treatment for 24 months. We evaluated changes in HbA1c, body weight, hypoglycemia events, and side effects. The control group consisted of 50 patients who underwent basal insulin therapy under identical clinical conditions.Results : At study completion, there were no significant differences in HbA1c improvement between the 4-OHA group and the control group [-1.41 vs -1.56% (-15.4 vs -17.1 mmol/mol), P=0.207]. There were also no differences in hypoglycemic events (n=10 vs 14, P=0.298) and weight gain (+2.79 vs +2.30kg, P=0.21)Conclusion : The 4-OHA combination therapy has sufficient glucose lowering effects in some patients. When insulin is not feasible, 4-OHA combination therapy may be considered as an alternative therapy.

Book Oral antidiabetic drugs and GLP 1 analogues in the treatment of type 2 diabetes

Download or read book Oral antidiabetic drugs and GLP 1 analogues in the treatment of type 2 diabetes written by Sics Editore and published by SICS Editore. This book was released on 2014-10-01 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral medication should be introduced at an early stage. In the absence of contraindications, medication should be started when the HbA1c concentration exceeds 6.5–7.0% (48–53 mmol/mol) despite non-pharmacological intervention. Metformin is the drug of choice. If one antidiabetic drug does not lower the HbA1c value to below 7.0 % (53 mmol/mol), add another and possibly a third antidiabetic drug unless there are contraindications. Insulin therapy must be initiated at the latest when HbA1c remains over 7.0% despite medication with oral antidiabetic drugs or with injectable GLP-1 analogues. A GLP-1 analogue may also be combined with basic insulin treatment.

Book Oral Hypoglycemic Agents   ECAB

Download or read book Oral Hypoglycemic Agents ECAB written by Abdul Hamid Zargar and published by Elsevier Health Sciences. This book was released on 2013-07-12 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though we have many advances in the development of oral hypoglycemic agents, an ideal drug for treating type 2 diabetes is still a distant reality. Today, physicians can choose from a variety of medications targeting numerous facets of disease, but each drug class poses some limitations. The age-old molecules, such as sulfonylureas and biguanides, are still valued because of their well-studied mode of action, safety, tolerability, and predictable pharmacodynamic effects. This book attempts to describe the historical aspects and advances in the arena of oral hypoglycemic agents, extended- and sustained-release formulations of glipizide and metformin (both of which have great promise in the treatment of type 2 diabetes mellitus) as well as evaluates the role of the group in diabetic foot infections.

Book Type 2 Diabetes

    Book Details:
  • Author : Barry J. Goldstein
  • Publisher : CRC Press
  • Release : 2016-04-19
  • ISBN : 084937958X
  • Pages : 610 pages

Download or read book Type 2 Diabetes written by Barry J. Goldstein and published by CRC Press. This book was released on 2016-04-19 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence and prevalence of type 2 diabetes mellitus have increased dramatically in modernized and developing nations over the past few decades. Thoroughly revised and expanded, this Second Edition responds to the epidemic and supplies a current overview and guide to the management of diabetes in the modern healthcare environment. This Second E

Book Index Medicus

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Book Oxford Textbook of Endocrinology and Diabetes

Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Book Nutrition and Diabetes

    Book Details:
  • Author : Emmanuel Opara
  • Publisher : CRC Press
  • Release : 2005-11-21
  • ISBN : 1420038796
  • Pages : 497 pages

Download or read book Nutrition and Diabetes written by Emmanuel Opara and published by CRC Press. This book was released on 2005-11-21 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes occurs at such an alarming rate that it is believed to be nearing epidemic proportions worldwide. Nutrition and Diabetes: Pathophysiology and Management is a comprehensive resource that examines the metabolic aberrations found in obesity that eventually lead to the development of diabetes. By focusing on the role diet has in the cause and

Book Developmental Biology of Gastrointestinal Hormones

Download or read book Developmental Biology of Gastrointestinal Hormones written by M. Wabitsch and published by Karger Medical and Scientific Publishers. This book was released on 2017-08-16 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gut not only represents the largest endocrine organ of the human body but is also profoundly involved in the control of metabolism through peptide hormones. Therefore, gastrointestinal hormones are acting via autocrine, paracrine, and classical endocrine pathways and regulate e.g. digestion, hunger, and satiety. Furthermore, they are important regulators of body weight, growth, and glucose metabolism, as well as of mood and behavior. Physicians and scientists in the field of pediatric endocrinology and diabetes, as well as in pediatric gastroenterology, require an extensive understanding of the origin of enteroendocrine cells, factors controlling their differentiation, hormone gene expression, secretion, function and, finally, the complex interaction with other organs, especially the central nervous system. In order to meet these needs, experts in the field have written up-to-date, comprehensive, and illustrated reviews presenting the current knowledge in the field of gastrointestinal endocrinology with a pediatric view. Those reviews comprise this latest volume of Endocrine Development.

Book Managing the Patient with Type II Diabetes

Download or read book Managing the Patient with Type II Diabetes written by Andrew L. Wilson and published by Jones & Bartlett Learning. This book was released on 1997 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Patient with Type II Diabetes is made up of recent articl es from Aspen's popular journal, Pharmacy Practice Management Quarterl y. With diabetes ranking very high on the scale of diseases utilizing the most health care resources, there is an increasing need to explore all avenues of managing the disease in a cost effective manner. This book addresses medication use, prescribing, glucose monitoring, patien t compliance, patient education, nutrition, and more.

Book Dietary Intake and Type 2 Diabetes

Download or read book Dietary Intake and Type 2 Diabetes written by Omorogieva Ojo and published by MDPI. This book was released on 2019-12-05 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of diabetes is on the increase in the UK and worldwide, partly due to changes in lifestyle which predispose individuals to overweight and obesity. It is estimated that about 90% of the currently diagnosed adults have type 2 diabetes, and based on the World Health Organisation (WHO) report, about 422 million adults were living with diabetes in 2014 compared with 108 million in 1980; this condition caused about 1.5 million deaths in 2012. In the United States of America, it is estimated that about 30.3 million adults are living with diabetes, with a further 1.5 million new diabetes cases diagnosed every year, representing an increasing prevalence of this condition. Diabetes represents a major public health challenge, despite advances in technology and the pharmaceutical industry. These problems may be in the form of acute or long-term complications. Therefore, in order to attenuate the problems of diabetes, management strategies usually include lifestyle changes such as increased physical activity and dietary interventions. Studies which evaluate the role of nutrition in the management of type 2 diabetes often involve human and animal models as these approaches enable us to have a broader and more in-depth understanding of the condition. In some cases, diabetes may co-exist with other conditions, such as stroke, and these may present unique challenges with regard to nutritional interventions. This Special Issue aims to evaluate the risk factors associated with type 2 diabetes and the role of the diet in the management of people with this condition. This evidence is drawn from both human and animal studies.

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1971 with total page 1204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Pharmacotherapy of Diabetes  New Developments

Download or read book Pharmacotherapy of Diabetes New Developments written by Carl Erik Mogensen and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types – 1 and 2 – of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine in general.

Book Textbook of Diabetes

    Book Details:
  • Author : Richard I. G. Holt
  • Publisher : John Wiley & Sons
  • Release : 2017-03-06
  • ISBN : 1118912020
  • Pages : 1104 pages

Download or read book Textbook of Diabetes written by Richard I. G. Holt and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including: Ischaemic Heart Disease Glucagon in Islet Regulation Microbiome and Diabetes Diabetes and Non-Alcoholic Fatty Liver Disease Diabetes and Cancer End of Life Care in Diabetes as well as a new section on Psychosocial aspects of diabetes. In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE. Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates Via the companion website, readers can access a host of additional online materials such as: 200 interactive MCQ's to allow readers to self-assess their clinical knowledge every figure from the book, available to download into presentations fully searchable chapter pdfs Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.

Book Nutrition and Diabetes

    Book Details:
  • Author : Emmanuel C. Opara
  • Publisher : CRC Press
  • Release : 2019-01-03
  • ISBN : 1351780107
  • Pages : 471 pages

Download or read book Nutrition and Diabetes written by Emmanuel C. Opara and published by CRC Press. This book was released on 2019-01-03 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches. Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.

Book Diabetes Literature Index

Download or read book Diabetes Literature Index written by and published by . This book was released on 1973 with total page 1598 pages. Available in PDF, EPUB and Kindle. Book excerpt: