Download or read book Emerging Therapeutic Approaches for Cystic Fibrosis written by Miquéias Lopes-Pacheco and published by Frontiers Media SA. This book was released on 2020-01-27 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Vitamin D From Biochemistry to Therapeutic Frontiers written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on 2024-07-06 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Vitamin D: From Biochemistry to Therapeutic Frontiers" offers an expansive exploration of this crucial nutrient's multifaceted role. Delve into the intricate biochemistry, comprehensive anatomy, and the significance of Vitamin D in holistic health. Uncover its diverse forms, the science behind D2 versus D3, and understand why this vitamin is vital for the body's optimal functioning. From bone health to immune system modulation, this treatise meticulously examines Vitamin D's involvement in various bodily functions. Learn how it influences bone formation, calcium regulation, and discover its surprising extra-skeletal roles in immune system fortification, cell growth, and neurological functions.

Download or read book Metaphors of Family Systems Theory written by Paul C. Rosenblatt and published by Guilford Press. This book was released on 1994 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: If family therapy is like a camera through which clients are able to view their lives, then the treatment method used by clinicians could be considered the lens, offering different ways of seeing. In Metaphors of Family Systems Theory, Paul C. Rosenblatt explores the metaphors of family systems theory that form the conceptual foundation - the lens - of a great deal of therapy, research, theory, education, and policy making in the family field. He demonstrates the value of testing out theoretical or alternative metaphors - other lenses - to provide new perspectives and a fresh means of gaining clarity. The literature that informs family therapy is rich with striking accounts of how therapeutic metaphors have helped to move families into healthier, energizing, freeing, and more satisfying relationships, yet little attention has been devoted to the development of alternative theoretical metaphors. This innovative new work investigates the uses and limitations of the standard metaphors of family systems theory. Perhaps more important, it also provides the means to generate alternative theoretical metaphors to stimulate new thinking about family systems. Rosenblatt asserts that the capacity to recognize metaphors will enable clinicians and clients to identify biases, hidden implications, and reification, as well as what may have been overlooked. He shows the way this ability also helps us to organize and remember information, and to better appreciate the multilayeredness of "reality". Initial chapters define metaphor and discuss family systems theory, as well as the uses and limitations of standard therapeutic metaphors. The chapters examine the notion of the family as an entity, themetaphor of "system", and the major systemic metaphors. Rosenblatt extends his analysis to the idea of family boundary and to the closely related metaphors of family subsystem, family boundary permeability, and family boundary ambiguity. He also analyzes the metaphors of family structure, systems control, family rules, and negative and positive feedback. Later chapters apply these ideas to the metaphors of communication, therapeutic goals, the therapist in the system, and family response to intervention. Rosenblatt Illustrates new insights with a variety of experience-based metaphors and presents strategies for the evaluation and development of new theoretical metaphors for family systems. Unique and innovative, this book offers a fresh perspective for anyone working with metaphors of family systems theory. Of special interest to family therapists, family researchers, social workers, and other mental health professionals working in the family field, it is especially useful as a text for courses in family systems theory, theories of family therapy, and theory construction.

Download or read book Therapeutic Process and Well Being in Forensic Psychiatry and Prison written by Manuela Dudeck and published by Frontiers Media SA. This book was released on 2021-02-17 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunogenicity of Proteins Used as Therapeutics written by Amy Rosenberg and published by Frontiers Media SA. This book was released on 2020-12-28 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Susan Richards is an employee of Sanofi and owns stock in the corporation. Topic Editor Bernard Maillere declares economic support from pharmaceutical companies (Novartis, Sanofi, and UCB) in the frame of collaborations aiming to evaluate the recognition by human T cells of therapeutic proteins and antibodies.

Download or read book Gene Therapy in the CNS Progress and Prospects for Novel Therapies written by Casper René Gøtzsche and published by Frontiers Media SA. This book was released on 2021-12-21 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The DNA Replication Machinery as Therapeutic Targets written by Andrew F. Gardner and published by Frontiers Media SA. This book was released on 2019-09-19 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins as well as future outlooks and needs.

Download or read book Frontiers in Clinical Drug Research Dementia Volume 2 written by José Juan Antonio Ibarra Arias and published by Bentham Science Publishers. This book was released on 2021-11-09 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, secondly, to establish preventive and therapeutic strategies in order to understand and mitigate this debilitating pathology. This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. The reviews contributed in these volume will provide readers with a current perspective on the subject. The topics covered in this volume include: - Comorbidities inducing mild cognitive impairment - an evaluation of the risk caused by some pathological conditions - Tau-targeted therapy in Alzheimer's disease - history and current state - Emerging nanotherapeutic strategies in Alzheimer's disease - Implication of dehydroepiandrosterone on dementia related to oxidative stress - Polyphenol compounds as potential therapeutic agents in Alzheimer’s disease The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists.

Download or read book New Frontiers in Offender Treatment written by Elizabeth L. Jeglic and published by Springer. This book was released on 2018-11-16 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews how new and promising evidence-based interventions are being used with those involved in the criminal justice system. While there has been an increased emphasis on evidence-based practice within forensic treatment, there remains a disjoint between what we know works and adapting these interventions to those involved in the criminal justice system. This book seeks to bridge that gap by providing an overview of what we know works and how that information has been translated into offender treatment. In addition, it highlights avenues where additional research is needed. This book is comprised of three parts: In the first part, current models of correctional treatment including the Risk, Needs, Responsivity Model, The Good Lives Model and Cognitive Behavioral Models are presented. In the second part, the chapters address clinical issues such as the therapeutic alliance, clinician factors, and diversity related issues that impact treatment outcome. In the third and final part of the book, adaptions of innovative and cutting-edge evidence-based treatments such as Dialectical Behavior Therapy, Trauma Informed Care, Mindfulness, Motivational Interviewing, Assertive Community Treatment, Multisystemic Treatment, New frontiers in Intimate Partner Violence treatment, and the current research on the treatment of those with psychopathy are presented. Research supporting these treatment approaches targeting areas such as self-management, psychological well-being, treatment engagement and retention and their relationship to recidivism will be reviewed, while their adaptation for use with forensic populations is discussed. The book concludes with the editors’ summary of the findings and a discussion of the future of evidence-based interventions within the field of forensic psychology.

Download or read book Environmental Arts Therapy written by Ian Siddons Heginworth and published by Routledge. This book was released on 2019-11-20 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Arts Therapy: The Wild Frontiers of the Heart describes what happens when we take the creative arts therapies and the people whom we work with out of doors in order to provide safe, structured and accompanied creative therapeutic healing experiences. The theoretical themes are developed along with illustrated examples of clinical practice across a variety of settings and locations. The work is introduced and co-edited by a pioneer in the field, Ian Siddons Heginworth, who describes the emergence of environmental arts therapy and its growth across the British Isles supported through the training course based in London. The following 12 chapters are written by contributing authors and creative arts therapy practitioners working with children, adults and elders in schools, adult mental health and private practice in Britain and Europe. A central focus of the book is the clinical populations and settings in which clinicians work, and it also describes the health benefits as well as the challenges faced when working out of doors. This is a book about the emergence of a new creative therapy modality in the British Isles. It shows the value of working with the natural cycles and seasons, using an integrative arts approach including dramatic enactment, role-play, poetry, art-making with natural materials, storytelling, and the use of bodywork through movement, sound, rhythm and the voice, all held and reflected by our encounters with and in nature. It is about our relationship with nature, creativity and therapeutic healing and is written for trainers, trainees and practitioners in the creative arts, psychotherapy and ecotherapy.

Download or read book Frontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry written by Paul E. Croarkin and published by Frontiers Media SA. This book was released on 2016-08-05 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry.

Download or read book Therapeutic Modulation of the Complement System Clinical Indications and Emerging Drug Leads written by John D. Lambris and published by Frontiers Media SA. This book was released on 2020-02-14 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system is a multi-tasking gatekeeper of innate immunity thatintricately interacts with other key defense systems, such as the endothelial barrier,contact activation and coagulation systems, in maintaining tissue immunosurveillanceand homeostasis. Its rapid and forceful activation in the bloodstream not onlyensures the effective containment of microbial infections through potent cytolyticmechanisms, but also alerts the adaptive immune compartment to ensure the mountingof a proper humoral immune response against foreign antigens. However, there isa lurking ‘dark side’ that can lead complement astray, fueling a self-perpetuatingvicious cycle of inflammation, exuberant immune activation and irreversible tissueinjury that collectively exacerbate both acute and chronic pathologies. Indeed,complement dysregulation or excessive activation have been widely recognized askey pathogenic drivers in a wide spectrum of inflammatory or immune-mediateddiseases. Targeted modulation of the complement system at various points ofthe cascade has revealed promising therapeutic targets for ameliorating diseasescores in a number of conditions ranging from ocular, neurodegenerative andthromboinflammatory disorders, to cancer, periodontal diseases, chronic hemolyticanemias, ischemia-reperfusion organ injury, antibody-mediated transplant rejectionand hemodialysis-triggered inflammation. Elegant pre-clinical studies employing a diversified toolbox of highly specificcomplement inhibitors in rodent or primate models of disease have opened newavenues of therapeutic exploration by providing proof of concept for the therapeuticefficacy of complement modulation. At the same time, the clinical experience gainedduring this last decade with the sole complement-specific drug currently in the clinic,eculizumab, has rekindled the interest of biopharmaceutical companies in developingnew and potent complement therapeutics for complement-driven diseases. In this respect, the complement field is witnessing a new surge of clinical trialsthat are evaluating the safety, PK/PD profile and clinical efficacy of promising drugcandidates in a number of clinical conditions driven by complement imbalance orover-activation.

Download or read book Frontiers in Clinical Drug Research Anti Cancer Agents Volume 8 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-12-03 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The eighth volume of the book features reviews on these topics: - Key data management elements in clinical trials for oncological therapeutics - Prospects for therapeutic targeting of microRNAs in brain tumors - Breast cancer vaccines: current status and future approach - Desmocollin-3 and cancer - MDM2-p53 antagonists under clinical evaluation: a promising cancer targeted therapy for cancer patients harbouring wild-type tp53 - Towards targeted therapy: anticancer agents targeting cell organelle mitochondria - Anticancer therapeutic strategies in gliomas: chemotherapy, immunotherapy, and molecularly targeted therapy in adults.

Download or read book The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs written by Arianna Carolina Rosa and published by Frontiers Media SA. This book was released on 2020-12-18 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Person Centred Therapy Today written by Dave Mearns and published by SAGE. This book was released on 2000-11-13 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: `At the risk of being directive, I would say you should buy this book. It contains some of the most stimulating and refreshing ideas to have emerged in the person-centred literature since On Becoming a Person '- Person Centred Practice Person-Centred Therapy Today makes a timely and significant contribution to the development of one of the most popular and widely-used therapeutic approaches. `This is a book that is rooted in the origins of person-centred therapy but stands at the cutting edge of new ideas developing in this tradition. It will reinvigorate those of us already immersed in this tradition. It should convince newcomers of the vitality and potential of this approach to thera

Download or read book Hallucinogens and Entactogens Establishing a New Class of Psychotherapeutic Drugs written by Stefan Borgwardt and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Safety Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies written by Guido Moll and published by Frontiers Media SA. This book was released on 2020-07-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: