Download or read book Theoretical Immunology Part Two written by Alan S. Perelson and published by CRC Press. This book was released on 2018-02-19 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology." The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Download or read book Theoretical Immunology part Ii written by Alan Perelson and published by Westview Press. This book was released on 1988-01-21 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomen
Download or read book Theoretical Immunology Part One written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-05 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology". The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Download or read book Theoretical Immunology part I written by Alan Perelson and published by Westview Press. This book was released on 1988-01-21 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomen
Download or read book Theoretical Immunology Part One written by Alan S. Perelson and published by CRC Press. This book was released on 2018-03-05 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology". The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.
Download or read book Theoretical Immunology written by George I. Bell and published by . This book was released on 1978 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Theoretical and Experimental Insights into Immunology written by Alan S. Perelson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, molecules and cells of the immune system. This book is an up-to-date discussion of the current state of modelling and theoretical work in immunology, of the impact of theory on experiment, and of future directions for theoretical research. Among the topics discussed are the function and evolution of the immune system, computer modelling of the humoral immune response and of idiotypic networks and idiotypic mimicry, T-cell memory, cryptic peptides, new views and models of AIDS and autoimmunity, and the shaping of the immune repertoire by early presented antigens and self immunoglobulin.
Download or read book Theories of Immune Networks written by Henri Atlan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen. Clonal selection was the name of the theory based on this idea and it has provided the main concepts to account for the known features of the immune response. More recently, immunologists have discovered a wealth of new facts, in the form of different regulatory cells (helpers, suppressors, antigen presenting cells), genetic determinations of immune responses such as those involved in graft re jections, different molecular structures responsible for intercellular interactions such as interleukins, cytokins, idiotype-antiidiotype recognition and others. While furthering our understanding of the local interactions (molecular and cellular) in volved in the immune response, these discoveries have led to a questioning of the simplicities of the classical clonal selection theory. It is clear today that every single immune response is a cooperative phenomenon involving several different molecular and cellular interactions taking place in a coupled manner. In addition, cross reactivity to different antigens has shown that responses of the whole im mune system to different antigens are not completely isolated from one another and that the history of encounters with different antigens plays a crucial role in the maturation of the whole system. Thus, problems of complexity, generation of di versity and self-organization have entered the field of immunology.
Download or read book The Mind The Brain And Complex Adaptive Systems written by Harold J. Morowitz and published by Routledge. This book was released on 2018-03-08 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based upon a conference held in May 1993, this book discusses the intersection of neurobiology, cognitive psychology and computational approaches to cognition.
Download or read book Immunology written by Hannah D. Zane and published by Saunders. This book was released on 2001 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: IMMUNOLOGY: Theoretical and Practical Concepts in Laboratory Medicine provides a comprehensive, yet concise, summary of fundamental and advanced immunologic concepts and procedures. This modern, up-to-date text contains new information regarding molecular techniques in the field. The text supplements the required procedures manuals by emphasizing the theoretical aspect of the methods, quality assurance, and the validity of test results, as well as the application of laboratory finding to the diagnosis and monitoring of representative disease states.
Download or read book Theories of Immune Networks written by Henri Atlan and published by Springer. This book was released on 1989-10-27 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system may be viewed as a network of interacting cells producing cooperative behavior with the properties of memory and learning. Like the central nervous system, it can be studied as a parallel computing network, endowed with cognitive capabilities. The contributions in this book discuss the various formal approaches available today to analyze the behavior of immune networks. The first part of the book presents empirical data on some molecular and cellular interactions, mainly idiotypic-antiidiotypic, which constitute the substrate for the connections between different cell populations. Automata network behavior can be used to model not only idiotypic-antiidiotypic interactions but also other interactions between different classes of lymphocytes as well as receptor-antigen interactions. Thus the concept of immune networks receives a more precise meaning. Two different approaches are then discussed. Part two discusses the "large" network approach made of all possible idiotypic-antiidiotypic interactions with cross-reactivity. Part three discusses the small network approach, better fitted to represent and analyze specific data on limited interactions. The book presents the first applications of neural network computation to immunology
Download or read book The Foundations of Immunology and their Pertinence to Medicine written by Peter Bretscher and published by FriesenPress. This book was released on with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Foundations of Immunology and their Pertinence to Medicine, Peter Bretscher describes how the few foundational concepts of immunology came about. He traces Jenner’s development of safe vaccination against small pox in the 1700’s, and how it led to the recognition of infectious disease by Koch and Pasteur in the 1880’s, and to the discovery of the Principles of Vaccination. The formulation of the Clonal Selection Theory in the 1950’s still provides a foundation for contemporary analysis of the immune system. Peter describes the main, and sometimes conflicting concepts, proposed in the last 50 years as to how immune responses are regulated. He develops a unique framework, and employs this to justify some tested and some speculative strategies to prevent and treat clinical conditions in five areas of medicine: Infectious Diseases, Cancer, Autoimmunity, Allergies and Transplantation. This book provides a platform for discussing contemporary immunological issues accessible to the non-specialist, medical students and medical practitioners. The platform challenges some of todays most popular paradigms. Foundations is written in a clear and jargon-free style.
Download or read book Theory And Control Of Dynamical Systems Applications To Systems In Biology written by Stig I Andersson and published by World Scientific. This book was released on 1992-05-26 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the mathematical modeling of complex system behavior, dynamical systems play an increasing role. The flexibility and very rich phenomenology exhibited by such systems make them indispensible in this context. Control theory for dynamical systems is also a highly active field of research where a number of important results have been achieved recently.This combined course and workshop deals with recent results regarding dynamical systems and control theory, primarily in differential geometric terms as well as the applications of these fields to biological systems, with an emphasis on various aspects of the immune system and on neural networks.
Download or read book The Quantal Theory of Immunity written by Kendall A. Smith and published by World Scientific. This book was released on 2010 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to ?count? the number of foreign antigenic molecular ?hits?, and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction. This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented. This molecular understanding of the immune system is especially important for the design of successful vaccines, and also explains why vaccines fail.
Download or read book Rediscovering the Immune System as an Integrated Organ written by Peter Bretscher and published by FriesenPress. This book was released on 2016-01-28 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mainstream view of the immune system is concerned with molecular and cellular details resulting in a picture of immense complexity. Many immunologists live with this complexity, hoping that a series of breakthroughs will eventually add up to a greater insight. However, the forest is ignored for the trees and a 'Systems Approach' is vital for a better understanding. Peter Bretscher develops here a unique perspective on how the immune system functions as an integrated organ, by taking account of observations and concepts at the 'level of system' that are often half forgotten or ignored. A colleague, on reading this book, wrote: "Those who have followed Peter's work these past 50 years will recognize this book for what it really is - a rare achievement, a scientific masterpiece. It is a must read for all those Immunologists and Clinicians who want to find effective immunological cures for the many debilitating health issues that confront us. Peter Bretscher has produced a lucid and logical exposition of the rules governing how the adaptive immune system responds to all foreign antigens whether bacterial, viral or modifications of the self, which emerge in cancer or autoimmune conditions. This book is a testament to Louis Pasteur's dictum that there is no applied science, just the application of basic science." Rediscovering the Immune System is written in a jargon-free and accessible style. This personal perspective is an ideal guide to the immune system for students, researchers and the engaged, general reader alike.
Download or read book Mathematical and Statistical Approaches to AIDS Epidemiology written by Carlos Castillo-Chavez and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 18 research articles of this volume discuss the major themes that have emerged from mathematical and statistical research in the epidemiology of HIV. The opening paper reviews important recent contributions. Five sections follow: Statistical Methodology and Forecasting, Infectivity and the HIV, Heterogeneity and HIV Transmission Dynamics, Social Dynamics and AIDS, and The Immune System and The HIV. In each, leading experts in AIDS epidemiology present the recent results. Some address the role of variable infectivity, heterogeneous mixing, and long periods of infectiousness in the dynamics of HIV; others concentrate on parameter estimation and short-term forecasting. The last section looks at the interaction between the HIV and the immune system.
Download or read book Artificial Immune Systems A New Computational Intelligence Approach written by Leandro Nunes de Castro and published by Springer Science & Business Media. This book was released on 2002-09-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Immune Systems (AIS) are adaptive systems inspired by the biological immune system and applied to problem solving. This book provides an accessible introduction that will be suitable for anyone who is beginning to study or work in this area. It gives a clear definition of an AIS, sets out the foundations of the topic (including basic algorithms), and analyses how the immune system relates to other biological systems and processes. No prior knowledge of immunology is needed - all the essential background information is covered in the introductory chapters. Key features of the book include: - A discussion of AIS in the context of Computational Intelligence; - Case studies in Autonomous Navigation, Computer Network Security, Job-Shop Scheduling and Data Analysis =B7 An extensive survey of applications; - A framework to help the reader design and understand AIS; - A web site with additional resources including pseudocodes for immune algorithms, and links to related sites. Written primarily for final year undergraduate and postgraduate students studying Artificial Intelligence, Evolutionary and Biologically Inspired Computing, this book will also be of interest to industrial and academic researchers working in related areas.
