Download or read book The Winding Road to Discovering IPS Cells written by Shin'ya Yamanaka and published by . This book was released on 2021 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The revolutionary discovery of induced pluripotent stem cells, or iPS cells, completely changed the world, particularly in the field of medical science. This groundbreaking achievement was made by Dr. Yamanaka Shinya of Kyoto University and won him the Nobel Prize for Physiology or Medicine in 2012. The road that led him to this accomplishment, however, was not an easy one; during his early days as a training orthopedic surgeon, Yamanaka was not skilled and was called "a hindrance" by his supervisor. He eventually changed course to become a researcher in the field of medical science and undertook postdoctoral studies in the United States, but he experienced a mild case of depression upon returning to Japan. Even when Yamanaka presented the results of his discovery of iPS cells, he could not immediately bask in the glory of his success, since many of his peers simply could not believe his achievement. In this volume, the Nobel Prize laureate talks openly about his life from his childhood days to his current daily life and discusses his views on the future of regenerative medicine. How were iPS cells developed and what can they do? Translated from a runaway bestseller in Japan and replete with a new preface for the English edition, this biography shows what science can do for mankind, and the possibilities that life holds." --back cover.
Download or read book Issues in Science and Theology Creative Pluralism written by Michael Fuller and published by Springer Nature. This book was released on 2022-06-28 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together selected papers from scientists, theologians and philosophers who took part in the 2021 conference of the European Society for the Study of Science and Theology based in Madrid, Spain. The contributions constitute a cutting-edge resource for considering questions from interdisciplinary perspectives, covering both the crucial role played by images and models in our thinking and also the limitations which are inherent in these linguistic devices. Questions addressed include: Can this use of images and models generate a creative pluralism, enabling us to think outside the disciplinary silos which are a feature of academic discourse? Can they enable fruitful, synergistic, interdisciplinary conversations? This book will appeal to students and academics alike, particularly those working in the fields of philosophy, theology, ethics and the history of science.
Download or read book Medical Applications of iPS Cells written by Haruhisa Inoue and published by Springer. This book was released on 2019-04-01 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.
Download or read book Induced Pluripotent Stem iPS Cells written by Andras Nagy and published by Springer Nature. This book was released on 2022-06-22 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive new edition presents protocols reflecting the great strides made in the study of induced pluripotent stem (iPS) cells. The collection explores new and improved methods for the generation, expansion, and maintenance of iPS cells from different tissue types, characterization of their differentiation pathways along different lineages, and their potential utility in tissue repair and regeneration. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, Second Edition aims to arm stem cell biologists, both novice and expert, with invaluable protocols that are currently being used in various laboratories around the world.
Download or read book Pluripotent Stem Cells written by Uma Lakshmipathy and published by . This book was released on 2013 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human pluripotent stem cells such as human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) with their unique developmental plasticity hold immense potential as cellular models for drug discovery and in regenerative medicine as a source for cell replacement. While hESC are derived from a developing embryo, iPSC are generated with forced expression of key transcription factors to convert adult somatic cells to ESC-like cells, a process termed reprogramming. Using iPSC overcomes ethical issues concerning the use of developing embryos and it can be generated from patient-specific cells for downstream applications. Pluripotent Stem Cells: Methods and Protocols highlights the best methods and systems for the entire work flow. Divided into four convenient sections, topics include a focus on producing iPSC from diverse somatic sources, media systems for expanding ESC and iPSC with detailed protocols for directed differentiation into specific lineages, commonly used cellular and molecular characterization methods, and the potential application of labeled stem cells with specific methods for cloning, gene delivery and cell engineering. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Pluripotent Stem Cells: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of this essential cellular feature.
Download or read book Induced Pluripotent Stem Cells and Human Disease written by Kursad Turksen and published by Humana. This book was released on 2022-07-29 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models. Reflecting the latest technology for generating induced pluripotent stem cells (iPS cells) and their initial characterization, the book explores techniques invaluable both for studies of disease-specific cell types and for their potential applications in regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols serves as a vital guide that is valuable for not only experts but also novices in the stem cell field.
Download or read book Stem Cell Genetics for Biomedical Research written by Raul Delgado-Morales and published by Springer. This book was released on 2018-06-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.
Download or read book Contemporary Heart Transplantation written by Linda Bogar and published by Springer. This book was released on 2020-09-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
Download or read book The Guerrilla and how to Fight Him written by and published by . This book was released on 1962 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Certain Victory written by Robert H. Scales and published by Potomac Books, Inc.. This book was released on 1998-02-27 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The official U.S. Army account of Army performance in the Gulf War, Certain Victory was originally published by the Office of the Chief of Staff, U.S. Army, in 1993. Brig. Gen. Scales, who headed the Army's Desert Storm Study Project, offers a highly readable and abundantly illustrated chronicle.
Download or read book The International Space Station written by Robert C. Dempsey and published by Government Printing Office. This book was released on 2017 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looks at the operations of the International Space Station from the perspective of the Houston flight control team, under the leadership of NASA's flight directors, who authored the book. The book provides insight into the vast amount of time and energy that these teams devote to the development, planning and integration of a mission before it is executed. The passion and attention to detail of the flight control team members, who are always ready to step up when things do not go well, is a hallmark of NASA human spaceflight operations. With tremendous support from the ISS program office and engineering community, the flight control team has made the International Space Station and the programs before it a success.
Download or read book Cardiac Regeneration written by Masaki Ieda and published by Springer. This book was released on 2017-10-27 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Download or read book An Introduction to Ray Tracing written by Andrew S. Glassner and published by Elsevier. This book was released on 1989-06-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The creation of ever more realistic 3-D images is central to the development of computer graphics. The ray tracing technique has become one of the most popular and powerful means by which photo-realistic images can now be created. The simplicity, elegance and ease of implementation makes ray tracing an essential part of understanding and exploiting state-of-the-art computer graphics. An Introduction to Ray Tracing develops from fundamental principles to advanced applications, providing "how-to" procedures as well as a detailed understanding of the scientific foundations of ray tracing. It is also richly illustrated with four-color and black-and-white plates. This is a book which will be welcomed by all concerned with modern computer graphics, image processing, and computer-aided design. Provides practical "how-to" information Contains high quality color plates of images created using ray tracing techniques Progresses from a basic understanding to the advanced science and application of ray tracing
Download or read book Extrusion written by Harold F. Giles Jr and published by William Andrew. This book was released on 2013-09-21 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Extrusion is designed to aid operators, engineers, and managers in extrusion processing in quickly answering practical day-to-day questions. The first part of the book provides the fundamental principles, for operators and engineers, of polymeric materials extrusion processing in single and twin screw extruders. The next section covers advanced topics including troubleshooting, auxiliary equipment, and coextrusion for operators, engineers, and managers. The final part provides applications case studies in key areas for engineers such as compounding, blown film, extrusion blow molding, coating, foam, and reprocessing. This practical guide to extrusion brings together both equipment and materials processing aspects. It covers basic and advanced topics, for reference and training, in thermoplastics processing in the extruder. Detailed reference data are provided on such important operating conditions as temperatures, start-up procedures, shear rates, pressure drops, and safety. A practical guide to the selection, design and optimization of extrusion processes and equipment Designed to improve production efficiency and product quality Focuses on practical fault analysis and troubleshooting techniques
Download or read book The Southern Pine Beetle written by and published by . This book was released on 1981 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Textbook of Vascular Medicine written by Rhian M. Touyz and published by Springer. This book was released on 2019-08-02 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Download or read book Spatial Biases in Perception and Cognition written by Timothy L. Hubbard and published by Cambridge University Press. This book was released on 2018-08-23 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous spatial biases influence navigation, interactions, and preferences in our environment. This volume considers their influences on perception and memory.
