Download or read book The Warburg Effect Regulation Under Siege The Intertwined Pathways in Health and Disease written by Concetta Bubici and published by Frontiers Media SA. This book was released on 2019-10-17 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.
Download or read book Luxury Arts of the Renaissance written by Marina Belozerskaya and published by Getty Publications. This book was released on 2005-10-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today we associate the Renaissance with painting, sculpture, and architecture—the “major” arts. Yet contemporaries often held the “minor” arts—gem-studded goldwork, richly embellished armor, splendid tapestries and embroideries, music, and ephemeral multi-media spectacles—in much higher esteem. Isabella d’Este, Marchesa of Mantua, was typical of the Italian nobility: she bequeathed to her children precious stone vases mounted in gold, engraved gems, ivories, and antique bronzes and marbles; her favorite ladies-in-waiting, by contrast, received mere paintings. Renaissance patrons and observers extolled finely wrought luxury artifacts for their exquisite craftsmanship and the symbolic capital of their components; paintings and sculptures in modest materials, although discussed by some literati, were of lesser consequence. This book endeavors to return to the mainstream material long marginalized as a result of historical and ideological biases of the intervening centuries. The author analyzes how luxury arts went from being lofty markers of ascendancy and discernment in the Renaissance to being dismissed as “decorative” or “minor” arts—extravagant trinkets of the rich unworthy of the status of Art. Then, by re-examining the objects themselves and their uses in their day, she shows how sumptuous creations constructed the world and taste of Renaissance women and men.
Download or read book The Renewal of Pagan Antiquity written by Aby Warburg and published by Getty Publications. This book was released on 1999 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of essays by the art historian Aby Warburg, these essays look beyond iconography to more psychological aspects of artistic creation: the conditions under which art was practised; its social and cultural contexts; and its conceivable historical meaning.
Download or read book The Next Step written by and published by Bbva-Open Mind. This book was released on 2017-03 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Next Step: Exponential Life presents essays on the potential of what are known as "exponential technologies"--those whose development is accelerating rapidly, such as robotics, artificial intelligence or industrial biology--considering their economic, social, environmental, ethical and even ontological implications. This book's premise is that humanity is at the beginning of a technological revolution that is evolving at a much faster pace than earlier ones--a revolution is so far-reaching it is destined to generate transformations we can only begin to imagine. Contributors include Aubrey D.N.J. de Grey, Jonathan Rossiter, Joseph A. Paradiso, Kevin Warwick, Huma Shah, Ramón López de Mántaras, Helen Papagiannis, Jay David Bolter, Maria Engberg, Robin Hanson, Stuart Russell, Darrell M. West, Francisco González, Chris Skinner, Steven Monroe Lipkin, S. Matthew Liao, James Giordano, Luciano Floridi, Seán Ó Héigeartaigh and Martin Rees.
Download or read book Epistemologies of the South written by Boaventura de Sousa Santos and published by Routledge. This book was released on 2015-11-17 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the concept of 'cognitive injustice': the failure to recognise the different ways of knowing by which people across the globe run their lives and provide meaning to their existence. Boaventura de Sousa Santos shows why global social justice is not possible without global cognitive justice. Santos argues that Western domination has profoundly marginalised knowledge and wisdom that had been in existence in the global South. She contends that today it is imperative to recover and valorize the epistemological diversity of the world. Epistemologies of the South outlines a new kind of bottom-up cosmopolitanism, in which conviviality, solidarity and life triumph against the logic of market-ridden greed and individualism.
Download or read book Towards a New Enlightenment written by and published by Turner. This book was released on 2019-09-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses key issues in understanding the decade 2008-2018 and its impact on the societies of the future. Brings together the articles B28of twenty-two prestigious international experts in different fields of thought. Through an informative approach, the essays form a transversal view of today's thinking. This is the tenth title of the Open Mind essay collection published by BBVA. A27.0We are living through years of great importance, marked by the unstoppable evolution of technology, science and the information society. This book brings together twenty-two essays written by prestigious researchers from the world's leading universities on areas as diverse as crucial to our future: climate change, artificial intelligence, economics, cyber-security and geopolitics, democracy, anthropology, new media, astrophysics and cosmology, nanotechnology, biomedicine, globalisation, gender theory and the cities of the future.
Download or read book Life Over Cancer written by Keith Block and published by Bantam. This book was released on 2009-04-21 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.
Download or read book Historical Perspectives of the Operational Art written by Michael D. Krause and published by Government Printing Office. This book was released on 2006-05 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: NOTE: NO FURTHER DISCOUNT FOR THIS PRINT PRODUCT--OVERSTOCK SALE -- Significantly reduced list price while supplies last Historical Perspectives of the Operational Art, a companion volume to Clayton R. Newell's and Michael D. Krause's On Operational Art, captures the doctrinal debate over the evolving concept of operational art-the critical link between strategy and tactics-in the face of the new complexities of warfare and the demands of irregular operations in the twenty-first century. Consisting of fifteen original essays selected and edited by Michael D. Krause in collaboration with R. Cody Phillips, the well-organized anthology presents the collective view of distinguished military historians and scholars that operational art must be adjusted to accommodate the changing circumstances happening around the world, especially when dealing with broad coalitions and alliances in regional environments and at an international level. Related products: The Rise of iWar: Identity, Information, and the Individualization of Modern Warfare can be found here: https://bookstore.gpo.gov/products/sku/008-000-01198-2 Yemen: A Different Political Paradigm in Context can be found here: https://bookstore.gpo.gov/products/sku/008-070-00865-3 A Masterpiece of Counterguerrilla Warfare: BG J. Franklin Bell in the Philippines 1901-1902 is avaialble here: https://bookstore.gpo.gov/products/sku/008-000-01000-5 Operational Culture for the Warfighter: Principles and Applications is available here: https://bookstore.gpo.gov/products/sku/008-000-01061-7
Download or read book Terrestrial Ecosystem Research Infrastructures written by Abad Chabbi and published by CRC Press. This book was released on 2017-03-03 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Terrestrial Ecosystem Research Infrastructures: Challenges and Opportunities reveals how environmental research infrastructures (RIs) provide new valuable insights on ecological processes that cannot be realized by more traditional short-term funding cycles and are integral to understand our changing world. This book bonds the latest state-of-the-science knowledge on environmental RIs, the challenges in creating them, their place in addressing scientific frontiers, and the new perspectives they bear. Each chapter is thoughtfully invested with fresh viewpoints from the environmental RI vantage as the authors explore and explain many topics such as the rationale and challenges in global change, field and modeling platforms, new tools, challenges in data management, distilling information into knowledge, and new developments in large-scale RIs. This work serves an advantageous guide for academics and practitioners alike who aim to deepen their knowledge in the field of science and project management, and logistics operations.
Download or read book Ethnobotany and Biocultural Diversities in the Balkans written by Andrea Pieroni and published by Springer. This book was released on 2014-11-14 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses recent and ongoing ethnobotanical studies in the Balkans. The book focuses on elaborating the relevance of such studies for future initiatives in this region, both in terms of sustainable and peaceful (trans-regional, trans-cultural) rural development. A multi-disciplinary viewpoint is utilized, with an incorporation of historical, ethnographic, linguistic, biological, nutritional and medical perspectives. The book is also authored by recognized scholars, who in the last decade have extensively researched the Balkan traditional knowledge systems as they pertain to perceptions of the natural world and especially plants. Ethnobotany and Biocultural Diversities in the Balkans is the first ethnobotany book on one of the most biologically and culturally diverse regions of the world and is a valuable resource for both scholars and students interested in the field of ethnobotany.
Download or read book Selforganization written by W. Krohn and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: may be complex without being able to be replaced by something »still more simple«. This became evident with the help of computer models of deterministic-recursive systems in which simple mathematical equation systems provide an extremely complex behavior. (2) Irregularity of nature is not treated as an anomaly but becomes the focus of research and thus is declared to be normal. One looks for regularity within irregularity. Non-equilibrium processes are recognized as the source of order and the search for equilibrium is replaced by the search for the dynamics of processes. (3) The classical system-environment model, according to which the adaptation of a system to its environment is controlled externally and according to which the adaptation of the system occurs in the course of a learning process, is replaced by a model of systemic closure. This closure is operational in so far as the effects produced by the system are the causes for the maintenance of systemic organization. If there is sufficient complexity, the systems perform internal self-observation and exert self-control (»Cognition« as understood by Maturana as self-perception and self-limitation, e. g. , that of a cell vis-a. -vis its environment). 22 But any information a system provides on its environment is a system-internal construct. The »reference to the other« is merely a special case of »self-reference«. The social sciences frequently have suffered from the careless way in which scientific ideas and models have been transferred.
Download or read book Goya written by Janis A. Tomlinson and published by Yale University Press. This book was released on 2002-03-11 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Francisco Goya y Lucientes (1746-1828) created magnificent paintings, tapestry designs, prints, and drawings over the course of his long and productive career. Women frequently appeared as the subjects of Goya's works, from his brilliantly painted cartoons for the Royal Tapestry Factory to his stunning portraits of some of the most powerful women in Madrid. This groundbreaking book is the first to examine the representations of women within Goya's multifaceted art, and in so doing, it sheds new light on the evolution of his artistic creativity as well as on the roles assumed by women in late eighteenth- and early nineteenth-century Spain. Many of Goya's most famous works are featured and explicated in this beautifully designed and produced book. The artist's famous tapestry cartoons are included, along with the tapestries woven after them for the royal palaces of the Prado and the Escorial. Goya's infamous Naked Maja and Clothed Maja are also highlighted, with a discussion on whether these works were painted at the same time and how they might have originally hung in relation to one another. Focus is also placed on Goya's more experimental prints and drawings, in which the artist depicted women alternatively as targets of satire, of sympathy, or of admiration. Essays by eminent authorities provide a historical and cultural context for Goya's work, including a discussion on the significance of fashion and dress during the period. The resultant volume is surely to be treasured by all who admire Goya's art and by those who are interested in women's issues of his time.
Download or read book Tactical Nuclear Weapons and NATO written by Douglas T. Stuart and published by . This book was released on 2012 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: is understudied, both inside and outside of government. Tactical weapons, although less awesome than their strategic siblings, carry significant security and political risks, and they have not received the attention that is commensurate to their importance. Second, it is clear that whatever the future of these arms, the status quo is unacceptable. It is past the time for NATO to make more resolute decisions, find a coherent strategy, and formulate more definite plans about its nuclear status. Consequently, decisions about the role of nuclear weapons within the Alliance and the associated supporting analysis are fundamental to the future identity of NATO. At the Lisbon Summit in Portugal in November 2010, the Alliance agreed to conduct the Deterrence and Defense Posture Review (DDPR). This effort is designed to answer these difficult questions prior to the upcoming NATO Summit in May 2012.
Download or read book Big Data in Organizations and the Role of Human Resource Management written by Tobias M. Scholz and published by Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften. This book was released on 2017 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big data are changing the way we work. This book conveys a theoretical understanding of big data and the related interactions on a socio-technological level as well as on the organizational level. Big data challenge the human resource department to take a new role. An organization's new competitive advantage is its employees augmented by big data.
Download or read book Human Rights Watch World Report written by and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book What Do Artists Know written by James Elkins and published by Penn State Press. This book was released on 2015-06-26 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each of the five volumes in the Stone Art Theory Institutes series, and the seminars on which they are based, brings together a range of scholars who are not always directly familiar with one another’s work. The outcome of each of these convergences is an extensive and “unpredictable conversation” on knotty and provocative issues about art. This third volume in the series, What Do Artists Know?, is about the education of artists. The MFA degree is notoriously poorly conceptualized, and now it is giving way to the PhD in art practice. Meanwhile, conversations on freshman courses in studio art continue to be bogged down by conflicting agendas. This book is about the theories that underwrite art education at all levels, the pertinent history of art education, and the most promising current conceptualizations. The contributors are Areti Adamopoulou, Glenn Adamson, Rina Arya, Louisa Avgita, Jan Baetens, Su Baker, Ciarín Benson, Andrew Blackley, Jeroen Boomgaard, Brad Buckley, William Conger, John Conomos, Christopher Csikszentmihályi, Anders Dahlgren, Jonathan Dronsfield, Marta Edling, Laurie Fendrich, Michael Fotiadis, Christopher Frayling, Miguel González Virgen, R.E.H. Gordon, Charles Green, Vanalyne Green, Barbara Jaffee, Tom McGuirk, William Marotti, Robert Nelson, Håkan Nilsson, Saul Ostrow, Daniel Palmer, Peter Plagens, Stephan Schmidt-Wulffen, Howard Singerman, Henk Slager, George Smith, Martin Søberg, Ann Sobiech Munson, Roy Sorensen, Bert Taken, Hilde Van Gelder, Frank Vigneron, Janneke Wesseling, Frances Whitehead, Gary Willis, and Yeung Yang.
Download or read book Humanitarianism Keywords written by and published by BRILL. This book was released on 2020-09-07 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humanitarianism: Keywords is a comprehensive dictionary designed as a compass for navigating the conceptual universe of humanitarianism. It is an intuitive toolkit to map contemporary humanitarianism and to explore its current and future articulations. The dictionary serves a broad readership of practitioners, students, and researchers by providing informed access to the extensive humanitarian vocabulary.
