Download or read book The War Against Hepatitis B written by William A. Muraskin and published by . This book was released on 1995 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of a group of scientists who set out to conquer hepatitis B, focusing on the International Task Force's encounters with opposition from economic and political forces. Draws on classified and confidential documents and on interviews with Task Force members, government representatives, and institutional officials to dramatize the turf wars, international politics, and internal tensions the Task Force overcame to lower prices of the vaccine against the disease and make universal immunization a priority. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Epidemiology in Military and Veteran Populations written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains papers presented at a conference which describe studies of a World War II hepatitis epidemic, a genetic analysis of substance use in veteran twins, hemorrhagic fever with renal syndrome, the psychological effects of military captivity, and dioxin in adipose tissue. Other papers discuss radiation risk studies in military populations and resources for epidemiologic research in Vietnam-era veterans. This volume should be of interest to epidemiologists, medical researchers, and others interested in public health.
Download or read book Review of the Fialuridine FIAU Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 1995-03-14 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June 1993 a clinical trial of fialuridine (FIAU), a promising new medication for hepatitis B, was abruptly terminated when one of the 15 out-patients participating in the National Institutes of Health (NIH) study was suddenly hospitalized with liver failure. Although all the remaining patients were contacted and told to stop taking their medication, six more subsequently developed severe toxicity. Five patients died, and two others were probably saved from death only by having liver transplants. In response to a request from the Secretary of the Department of Health and Human Services, the IOM committee has analyzed the FIAU clinical trials, making recommendations for additional safeguards for the conduct of future clinical trials. This evaluation included the review of documents pertaining to investigational new drug submissions, protocols and consent forms from other clinical trials, as well as information available from other clinical and preclinical experience with compounds related to FIAU and its parent drug, fiacitibine (FIAC), which is metabolized to FIAU. The committee does not seek to affix responsibility for the adverse outcome of this NIH trial, but instead focuses on whether any rules or procedures governing the clinical trials process itself need to be changed, and if so, what burdens or costs such changes might place on future clinical trials.
Download or read book Canadian Immunization Guide written by Canada. Comité consultatif national de l'immunisation and published by . This book was released on 2006 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.
Download or read book Vaccine The Controversial Story of Medicine s Greatest Lifesaver written by Arthur Allen and published by W. W. Norton & Company. This book was released on 2008-05-17 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.
Download or read book Dangerous Medicine written by Sydney A. Halpern and published by Yale University Press. This book was released on 2021-11-23 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold history of America’s mid-twentieth-century program of hepatitis infection research, its scientists’ aspirations, and the damage the project caused human subjects From 1942 through 1972, American biomedical researchers deliberately infected people with hepatitis. Government-sponsored researchers were attempting to discover the basic features of the disease and the viruses causing it, and to develop interventions that would quell recurring outbreaks. Drawing from extensive archival research and in-person interviews, Sydney Halpern traces the hepatitis program from its origins in World War II through its expansion during the initial Cold War years, to its demise in the early 1970s amid an outcry over research abuse. The subjects in hepatitis studies were members of stigmatized groups—conscientious objectors, prison inmates, the mentally ill, and developmentally disabled adults and children. The book reveals how researchers invoked military and scientific imperatives and the rhetoric of a common good to win support for the experiments and access to recruits. Halpern examines the participants’ long-term health consequences and raises troubling questions about hazardous human experiments aimed at controlling today’s epidemic diseases.
Download or read book The War Against Hepatitis B written by William A. Muraskin and published by . This book was released on 1995 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vaccines A Biography written by Andrew W. Artenstein and published by Springer Science & Business Media. This book was released on 2009-12-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.
Download or read book Chronic Hepatitis B and C written by Chiaho Shih and published by World Scientific. This book was released on 2013 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of the book is very broad, covering a wide range of areas in HBV/HDV and HCV research, including both basic and clinical science. The selected topics range from epidemiology, immunology, molecular virology and oncology, to clinical therapy.Chronic Hepatitis B and C consists of 14 chapters, each being a review of a special topic on HBV or HCV. While review articles on a special topic can be found in periodical journals, they tend to be more restricted in presentation. Therefore, this book will provide more in-depth coverage of what are presented as "unpublished results" and "data not shown" in journal articles. Furthermore, several authors in this book do not write review articles regularly. Some authors wrote reviews on a specific topic regularly, but they tried a new topic in this book (e.g., Dr. YF Liaw on "natural course," Dr. Shih on "virion release," Dr. Michael Lai on "lymphotropism of HCV," etc. ⋯). Overall, the book will offer useful information at the cutting age.Sample Chapter(s)
Download or read book The politics of vaccination written by Christine Holmberg and published by Manchester University Press. This book was released on 2017-03-16 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This electronic version has been made available under a Creative Commons (BY-NC-ND) open access license. Mass vaccination campaigns are political projects that presume to protect individuals, communities, and societies. Like other pervasive expressions of state power - taxing, policing, conscripting - mass vaccination arouses anxiety in some people but sentiments of civic duty and shared solidarity in others. This collection of essays gives a comparative overview of vaccination at different times, in widely different places and under different types of political regime. Core themes in the chapters include immunisation as an element of state formation; citizens' articulation of seeing (or not seeing) their needs incorporated into public health practice; allegations that donors of development aid have too much influence on third-world health policies; and an ideological shift that regards vaccines more as profitable commodities than as essential tools of public health.
Download or read book Vaccinated written by Paul A. Offit, M.D. and published by HarperCollins. This book was released on 2022-02-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases—including often devastating ones such as mumps and rubella—practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career. Offit makes an eloquent and compelling case for Hilleman’s importance, arguing that, like Jonas Salk, his name should be known to everyone. But Vaccinated is also enriched and enlivened by a look at vaccines in the context of modern medical science and history, ranging across the globe and throughout time to take in a fascinating cast of hundreds, providing a vital contribution to the continuing debate over the value of vaccines.
Download or read book Hepatitis B written by Baruch S. Blumberg and published by Princeton University Press. This book was released on 2018-06-05 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 375 million people are infected with the hepatitis B virus. It has killed more people than AIDS and also causes millions of cases of liver cancer. The discovery of this deadly virus and the vaccine against it--a vaccine that is sharply decreasing the infection rate worldwide and is probably the first effective cancer vaccine--was one of the great triumphs of twentieth-century medicine. And it almost didn't happen. With wit and insight, this scientific memoir and story of discovery describes how Baruch Blumberg and a team of researchers found a virus they were not looking for and created a vaccine for a disease they previously knew little about--work that took the author around the world and won him the Nobel Prize. Blumberg and his collaborators were investigating relationships between gene distribution and disease susceptibility, research that was yielding interesting data but no real breakthroughs. Many viewed their work as more field trip than science. But, through decades of hard work and investigative twists and turns, their pursuit led to the hepatitis B antigen, the elusive virus itself, and, ultimately, the vaccine. As he takes the reader through the detective work that culminated in his incredible discovery, the author recounts with immediacy exciting moments in the lab and in the field--from a hair-raising flight to Africa to an unpleasant encounter with Alaskan sled dogs. The hepatitis B story is more than a fascinating chronicle of a major discovery. What Blumberg followed to the virus was a trail of remarkable "accidents" that happen when scientists seek answers to interesting questions. Those events, combined with the investigator's determined persistence, resulted in studies that generated a pharmaceutical industry, have far-flung public-health applications, and saved millions of lives.
Download or read book HIV and the Blood Supply written by Institute of Medicine and published by National Academies Press. This book was released on 1995-10-05 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early years of the AIDS epidemic, thousands of Americans became infected with HIV through the nation's blood supply. Because little reliable information existed at the time AIDS first began showing up in hemophiliacs and in others who had received transfusions, experts disagreed about whether blood and blood products could transmit the disease. During this period of great uncertainty, decision-making regarding the blood supply became increasingly difficult and fraught with risk. This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system. The book focuses on critical decisions as information about the danger to the blood supply emerged. The committee draws conclusions about what was doneâ€"and recommends what should be done to produce better outcomes in the face of future threats to blood safety. The committee frames its analysis around four critical area: Product treatmentâ€"Could effective methods for inactivating HIV in blood have been introduced sooner? Donor screening and referralâ€"including a review of screening to exlude high-risk individuals. Regulations and recall of contaminated bloodâ€"analyzing decisions by federal agencies and the private sector. Risk communicationâ€"examining whether infections could have been averted by better communication of the risks.
Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline
Download or read book Hepatitis B Virus and Liver Disease written by Jia-Horng Kao and published by Springer. This book was released on 2018-01-12 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem ent of patients with chronic HBV infection and investigation of HBV infection.
Download or read book War Epidemics written by Matthew Smallman-Raynor and published by OUP Oxford. This book was released on 2004-06-17 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Down the ages, war epidemics have decimated the fighting strength of armies, caused the suspension and cancellation of military operations, and have brought havoc to the civil populations of belligerent and non-belligerent states alike. This book examines the historical occurrence and geographical spread of infectious diseases in association with past wars. It addresses an intrinsically geographical question: how are the spatial dynamics of epidemics influenced by military operations and the directives of war? The term historical geography in the title indicates the authors' primary concern with qualitative analyses of archival source materials over a 150-year time period from 1850, and this is combined with quantitative analyses less frequently associated with historical studies. Written from the viewpoints of historical geography, epidemiology, and spatial analysis, this book examines in four parts the historical occurrence and geographical spread of infectious diseases in association with wars. Part I: War and Disease, surveys war-disease associations from early times to 1850. Part II: Temporal Trends studies time trends since 1850. Part III: A Regional Pattern of War Epidemics, examines grand themes in the war-disease complex. Part IV: Prospects, considers a series of war-related issues of epidemiological significance in the twenty-first century.
Download or read book Hepatitis B written by Baruch S. Blumberg and published by Princeton University Press. This book was released on 2002 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 375 million people are infected with the hepatitis B virus. It has killed more people than AIDS and also causes millions of cases of liver cancer. The discovery of this deadly virus and the vaccine against it--a vaccine that is sharply decreasing the infection rate worldwide and is probably the first effective cancer vaccine--was one of the great triumphs of twentieth-century medicine. And it almost didn't happen. With wit and insight, this scientific memoir and story of discovery describes how Baruch Blumberg and a team of researchers found a virus they were not looking for and created a vaccine for a disease they previously knew little about--work that took the author around the world and won him the Nobel Prize. Blumberg and his collaborators were investigating relationships between gene distribution and disease susceptibility, research that was yielding interesting data but no real breakthroughs. Many viewed their work as more field trip than science. But, through decades of hard work and investigative twists and turns, their pursuit led to the hepatitis B antigen, the elusive virus itself, and, ultimately, the vaccine. As he takes the reader through the detective work that culminated in his incredible discovery, the author recounts with immediacy exciting moments in the lab and in the field--from a hair-raising flight to Africa to an unpleasant encounter with Alaskan sled dogs. The hepatitis B story is more than a fascinating chronicle of a major discovery. What Blumberg followed to the virus was a trail of remarkable "accidents" that happen when scientists seek answers to interesting questions. Those events, combined with the investigator's determined persistence, resulted in studies that generated a pharmaceutical industry, have far-flung public-health applications, and saved millions of lives.
