Download or read book The Vroman Effect written by C. H. Bamford and published by VSP. This book was released on 1992-12-01 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of specific antibodies as probes and detectors for adsorbed proteins by Dr. Leo Vroman and co-workers in the 1960s and 1970s confirmed his earlier observations and suspicions that blood protein adsorption involved a hierarchical series of collision, adsorption, and exchange processes. These observations and concepts were confirmed by other scientists and came to be known as 'the Vroman effect'. The core concept of the Vroman effect admits many approaches and over-reaches complex and not fully resolved questions of enzymology, transport phenomena, the statistical mechanics of protein conformation, longrange forces in liquids, and surface physics. This volume contains the presentations from the symposium which was held in honour of the 75th birhday of Dr. Leo Vroman, in Gouda, The Netherlands, and deals with various aspects of the Vroman effect.
Download or read book The Vroman Effect in Separated Flows written by Charles Andrew LeDuc and published by . This book was released on 1995 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Vroman Effect written by Seung-Yong Jung and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigations of specific and nonspecific interactions of biomolecules at liquid/solid interfaces are presented. To investigate specific multivalent ligand-receptor interactions, bivalent antibodies and haptens bound to solid supported membrane were used as models for ligand-receptor coupling. Novel microfabrication strategies, which included spatially addressed bilayer arrays and heterogeneous microfluidic assays, in conjunction with total internal reflection microscopy, was employed to achieve this goal. These high throughput techniques allow thermodynamic data of binding interactions to be acquired with only a few microliters of analyte and superior signal to noise. The results yield both the first and second dissociation constant for bivalent IgG antibodies with membrane bound hapten molecules. Studies were conducted both as a function of hapten density and cholesterol content in the membrane. Another research area of this dissertation is the molecular level description of nonspecific adsorption and displacement of the model protein, fibrinogen, onto hydrophilic surfaces. Techniques such as atomic force microscopy, immunochemical assays, fluorescence microscopy, and vibrational sum frequency spectroscopy were employed to probe this system. The results demonstrate that the protein's [alpha]C domains play the critical role. When fibrinogen is adsorbed to a hydrophilic surface via these moieties, its displacement rate in the presence of human plasma is approximately 170 times faster than when these domains are not in direct surface contact. Even more significantly, spectroscopic studies show evidence for highly aligned Arg and Lys residues interacting with the negatively charged substrate only when the [alpha]C domains make direct surface contact. The interfacial ordering of these residues appears to be the hallmark of a weak and labile electrostatic attraction between the substrate and the adsorbed macromolecule.
Download or read book Tissue Engineering written by Bernhard Palsson and published by CRC Press. This book was released on 2003-03-26 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the new Principles and Applications in Engineering series, Tissue Engineering provides an overview of the major physiologic systems of current interest to biomedical engineers: cardiovascular, endocrine, nervous, visual, auditory, gastrointestinal, and respiratory. It contains useful definitions, tables of basic physiologic data, and an introduction to the literature. Then, the book reviews the status of tissue engineering of specific organs, including bone marrow, skeletal muscle, and cartilage. Readers will acquire a good understanding of the engineering and cell biological fundamentals of tissue engineering and will develop ideas for further development of this emerging and important field.
Download or read book Biopolymers at Interfaces Second Edition written by Martin Malmsten and published by CRC Press. This book was released on 2003-01-15 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition features research from nearly 60 of the profession's most distinguished international authorities. Recognizing emerging developments in biopolymer systems research with fully updated and expanded chapters, the second edition discusses the biopolymer-based multilayer structures and their application in biosensors, the progress made in the understanding of protein behaviour at the air-water interface, experimental findings in ellipsometry and reflectometry, and recent developments concerning protein interfacial behaviour in microfabricated total analysis systems and microarrays. With over 3000 references, this is an essential reference for professionals and students in surface, pharmaceutical, colloid, polymer, and medicinal chemistry; chemical, formulation, and application engineering; and pharmacy.
Download or read book Proteins at Interfaces II written by and published by . This book was released on 1995 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry of Medical and Dental Materials written by John W Nicholson and published by Royal Society of Chemistry. This book was released on 2020-05-28 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: With synthetic implants such as hip joints, heart valves and dental crowns now routinely used in the human body for medical purposes, study of the metals, ceramics and polymers used in these repairs is more important than ever. The Chemistry of Medical and Dental Materials examines the properties and interactions of these materials within the body at a molecular level, and includes discussion of bioengineering and cell biology, with accounts of the surgical procedures used, as well as extensive coverage of the possible biological reactions to the presence of foreign materials in the body. Acknowledging the substantial growth of the biomaterials field since the first edition, this second edition sees each chapter comprehensively revised and updated. The new edition also includes a new chapter on ethical perspectives, covering issues from animal and human subject testing to the availability of treatments for poorer socio-economic groups. With detailed reviews of the current literature, this book will be a key resource for researchers and practitioners in biomaterials science and dental biomaterials who are involved in the development of new and improved repair materials.
Download or read book Biomaterials Science written by William R Wagner and published by Academic Press. This book was released on 2020-05-23 with total page 1612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters
Download or read book Blood Compatible Materials and Devices written by Michael Szycher and published by CRC Press. This book was released on 1990-01-18 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers in Tissue Engineering written by C.W. Patrick and published by Elsevier. This book was released on 1998-02-20 with total page 717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.
Download or read book Polyurethanes in Biomedical Applications written by NinaM.K. Lamba and published by Routledge. This book was released on 2017-10-19 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyurethanes in Biomedical Applications studies the use of polyurethanes in implanted medical devices. This analysis describes the concepts of polymer science, the manufacture of polyurethanes, and the biological responses to implant polyurethanes, reflecting the developments in biomaterials science and the interdisciplinary nature of bioengineering.
Download or read book Bioprospecting of Enzymes in Industry Healthcare and Sustainable Environment written by Hrudayanath Thatoi and published by Springer Nature. This book was released on 2021-01-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology. This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.
Download or read book Modern Aspects of Protein Adsorption on Biomaterials written by E Missirlis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book relates to the scientific records of a workshop held in Patras, Greece, in June 1989, under the auspices and with financial support of the European Economic Communities (Concerted Action EUROBIOMAT - Hemocompatibility - of the Medical Research Programme, Project: 11.1.212). This concerted action promotes the collaboration on science and technology on the particular field of hemocompatible biomaterials: exchange of experts, scholarships and scientific workshops within the EC-member countries and COST countries such as Sweden, Finland, Turkey, Switzerland. The first part of this monography refers to the oral presentations of the par ticipants. The second part gives the book its unique character: the scientific discussion on updated aspects of protein adsorption of synthetic polymers in contact with blood. This second part is subdivided into nine chapters where specific topics were discussed freely, open-minded and even controversially. This book intends to elucidate recurrent questions concerning the initial event when blood contacts artificial surfaces. Young investigators will consider this book to be appropriate to get familiar with the scientific background and the most relevant techniques and methods.
Download or read book Biomedical Engineering Handbook 2 written by Joseph D. Bronzino and published by Springer Science & Business Media. This book was released on 2000-02-15 with total page 1528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Measuring Biological Impacts of Nanomaterials written by Joachim Wegener and published by Springer. This book was released on 2016-02-02 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.
Download or read book Nuclear Magnetic Resonance Studies of Interfacial Phenomena written by Vladimir M. Gun'ko and published by CRC Press. This book was released on 2013-04-08 with total page 1035 pages. Available in PDF, EPUB and Kindle. Book excerpt: Properties and applications of high surface area materials depend on interfacial phenomena, including diffusion, sorption, dissolution, solvation, surface reactions, catalysis, and phase transitions. Among the physicochemical methods that give useful information regarding these complex phenomena, nuclear magnetic resonance (NMR) spectroscopy is the
Download or read book Bio Nano Interfaces written by Wolfgang Parak and published by CRC Press. This book was released on 2024-02-27 with total page 1480 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades, bio-nano interfaces have become a popular topic of research. The interface between biology (e.g., cells, proteins) and man-made materials (e.g., surfaces of labware, medical devices/implants, etc., that are exposed to the biological matter) has always been important, way before the terms of nanotechnology and nanoscience were coined. Nanotechnology brought new techniques into play, with which such interfaces can be investigated with an additional viewpoint. This book is a collection of articles spanning two decades that shows how the newer publications have evolved from the older ones. This allows the reader to see the development in the field not only technically but also conceptually. The book is, in particular, suitable for the researchers and general readers who are looking for inspiration on how ideas develop over decades.
