Download or read book The Vascular Smooth Muscle Cell written by and published by Elsevier. This book was released on 1995-10-24 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells. Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study Appeals to both the basic biologist and to the biomedical researcher of vascular disease

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Download or read book Muscle Cell and Tissue written by Kunihiro Sakuma and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to complete tissue regeneration, various cells (neuronal, skeletal and smooth) interact coordinately with each other. This book, Muscle Cell and Tissue - Current Status of Research Field, deals with current progress and perspectives in a variety of topics on the skeletal and smooth muscle, stem cells, regeneration, disease or therapeutics. Novel applications for cell and tissue engineering including cell therapy, tissue models and disease pathology modeling are introduced. This book also deals with the differentiation/de-differentiation process of vascular smooth muscle cells in health and disease. Furthermore, natural products to reverse metabolic syndromes are descriptively reviewed. These chapters can be interesting for graduate students, teachers, physicians, executives and researchers in the field of molecular biology and regenerative medicine.

Download or read book Vascular Smooth Muscle written by Maurice F. Crass and published by . This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The ...

Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cellular Aspects of Smooth Muscle Function written by C. Y. Kao and published by Cambridge University Press. This book was released on 1997-08-28 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.

Download or read book Fundamentals of Vascular Biology written by Margarethe Geiger and published by Springer. This book was released on 2019-05-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master ́s Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field.

Download or read book Inflammatory Atherosclerosis written by Richard James Frink and published by Heart Research Foundation Sacrament. This book was released on 2002 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biochemistry of Smooth Muscle Contraction written by Michael Barany and published by Elsevier. This book was released on 1996-01-04 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.

Download or read book Vascular Smooth Muscle written by Chi-Ming Hai and published by World Scientific. This book was released on 2016-10-12 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents key concepts in the structure and function of vascular smooth muscle cells in health and disease. Supplemental reading may be drawn from the extensive references listed at the end of each chapter. Vascular smooth muscle cell is the major cell type in blood vessels. Dysfunction of vascular smooth muscle cells is an important cause of vascular diseases, for example, atherosclerosis, hypertension, and circulatory shock. Vascular smooth muscle cells are phenotypically plastic, capable of switching between two major phenotypes — contractile/differentiated phenotype and invasive/proliferative phenotype in response to environmental clues. Chapter 1 introduces the major areas of research presented in this monograph. Chapters 2 to 4 address the structure and function of the contractile/differentiated phenotype of vascular smooth muscle cell. Chapters 5 and 6 address the developmental basis of vascular smooth muscle cell phenotype and structure and function of podosomes (invasive organelles) in the invasive/proliferative phenotype of vascular smooth muscle cell. Chapters 7 to 9 address the role of vascular smooth muscle cell dysfunction in vascular diseases — atherosclerosis, hypertension, and circulatory shock. Contents:Introduction (Chi-Ming Hai)Structure of Differentiated/Contractile Vascular Smooth Muscle Cells (Thomas J Eddinger)Vascular Structure and Function (Paul H Ratz)Actin Filament Dynamics During Vascular Smooth Muscle Contraction (William C Cole and Michael P Walsh)Developmental Basis of Vascular Smooth Muscle Cell Phenotypes (Christine Cheung and B C Narmada)Regulation of Podosomes in Vascular Smooth Muscle Cell Invasion of the Extracellular Matrix (Alan Mak)Vascular Smooth Muscle Cell Proliferation and Invasion in Atherosclerosis (Chi-Ming Hai)The Role of Non-Coding RNA in the Control of Vascular Contractility and Disease (C J Nicholson and K G Morgan)Vascular Smooth Muscle Cells as Therapeutic Target for the Treatment of Circulatory Shock (Liangming Liu, Tao Li and Chengyang Duan) Readership: This book will be a useful reference for graduate students, post-doctoral fellows, and scientists who work on vascular biology, as well as physicians who work on vascular medicine.

Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Download or read book Cardiovascular Development written by Xu Peng and published by Humana Press. This book was released on 2012-01-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: sCongenital heart disease is the leading cause of infant death and affects approximately one in every 100 babies born in the United States. The study of cardiovascular development has acquired new momentum in last twenty years due to the advancement of modern molecular biology and new available equipments and techniques. In Cardiovascular Development: Methods and Protocols expert researchers in the field in the field detail many of the methods which are now commonly used in the field of cardiovascular development research. These include methods and technique for using different organisms for cardiovascular developmental research, using cell and molecular biology methods to study cardiovascular development, as well as other available techniques for cardiovascular development research. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiovascular Development: Methods and Protocols seeks to aid scientists in understanding new state-of-the-art techniques in the field of cardiovascular development research including in vivo imaging and Bioinformatics.

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by Springer Nature. This book was released on 2020-07-30 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.

Download or read book Systems Biology and Its Application in TCM Formulas Research written by Wei-Dong Zhang and published by Academic Press. This book was released on 2018-02-16 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research

Download or read book Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues written by Haruo Sugi and published by IntechOpen. This book was released on 2012-07-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 17 short review articles classified into 3 parts. Part I consists of 7 articles dealing with basic aspects of contractile mechanism in skeletal and smooth muscle cells and also function of melanocytes having many properties common to those of smooth muscles. Part II and Part III contain articles dealing with pathological aspects of cardiac and smooth muscle cell functions, and dealing with factors influencing structure and function of cardiac and smooth muscle cells and tissues. The Editor believes that these articles are stimulating and informative for readers interested in basic, pathological and clinical aspects of muscle cells and tissues.

Download or read book Hypertension written by Rhian M. Touyz and published by Humana. This book was released on 2017-01-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive protocols that researchers can use to dissect out fundamental principles and molecular mechanisms of hypertension, extending from genetics of experimental hypertension to biomarkers in clinical hypertension. Hypertension: Methods and Protocols guides readers through chapters on genetics and mmics of hypertension; the Renin-Angiotensin-Aldosterone System; vasoactive agents and hypertension; signal transduction and reactive oxygen species; novel cell models and approaches to study molecular mechanisms of hypertension; vascular physiology; and new approaches to manipulate mouse models to study molecular mechanisms of hypertension. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hypertension: Methods and Protocols aims to ensure successful results in the further study of this vital field.