Download or read book Empirical Likelihood Methods in Biomedicine and Health written by Albert Vexler and published by CRC Press. This book was released on 2018-09-03 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical Likelihood Methods in Biomedicine and Health provides a compendium of nonparametric likelihood statistical techniques in the perspective of health research applications. It includes detailed descriptions of the theoretical underpinnings of recently developed empirical likelihood-based methods. The emphasis throughout is on the application of the methods to the health sciences, with worked examples using real data. Provides a systematic overview of novel empirical likelihood techniques. Presents a good balance of theory, methods, and applications. Features detailed worked examples to illustrate the application of the methods. Includes R code for implementation. The book material is attractive and easily understandable to scientists who are new to the research area and may attract statisticians interested in learning more about advanced nonparametric topics including various modern empirical likelihood methods. The book can be used by graduate students majoring in biostatistics, or in a related field, particularly for those who are interested in nonparametric methods with direct applications in Biomedicine.

Download or read book Empirical Likelihood written by Art B. Owen and published by CRC Press. This book was released on 2001-05-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical likelihood provides inferences whose validity does not depend on specifying a parametric model for the data. Because it uses a likelihood, the method has certain inherent advantages over resampling methods: it uses the data to determine the shape of the confidence regions, and it makes it easy to combined data from multiple sources. It al

Download or read book Sample Surveys Inference and Analysis written by and published by Morgan Kaufmann. This book was released on 2009-09-02 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistics_29B contains the most comprehensive account of sample surveys theory and practice to date. It is a second volume on sample surveys, with the goal of updating and extending the sampling volume published as volume 6 of the Handbook of Statistics in 1988. The present handbook is divided into two volumes (29A and 29B), with a total of 41 chapters, covering current developments in almost every aspect of sample surveys, with references to important contributions and available software. It can serve as a self contained guide to researchers and practitioners, with appropriate balance between theory and real life applications. Each of the two volumes is divided into three parts, with each part preceded by an introduction, summarizing the main developments in the areas covered in that part. Volume 1 deals with methods of sample selection and data processing, with the later including editing and imputation, handling of outliers and measurement errors, and methods of disclosure control. The volume contains also a large variety of applications in specialized areas such as household and business surveys, marketing research, opinion polls and censuses. Volume 2 is concerned with inference, distinguishing between design-based and model-based methods and focusing on specific problems such as small area estimation, analysis of longitudinal data, categorical data analysis and inference on distribution functions. The volume contains also chapters dealing with case-control studies, asymptotic properties of estimators and decision theoretic aspects. - Comprehensive account of recent developments in sample survey theory and practice - Covers a wide variety of diverse applications - Comprehensive bibliography

Download or read book Sampling Theory and Practice written by Changbao Wu and published by Springer Nature. This book was released on 2020-05-15 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three parts of this book on survey methodology combine an introduction to basic sampling theory, engaging presentation of topics that reflect current research trends, and informed discussion of the problems commonly encountered in survey practice. These related aspects of survey methodology rarely appear together under a single connected roof, making this book a unique combination of materials for teaching, research and practice in survey sampling. Basic knowledge of probability theory and statistical inference is assumed, but no prior exposure to survey sampling is required. The first part focuses on the design-based approach to finite population sampling. It contains a rigorous coverage of basic sampling designs, related estimation theory, model-based prediction approach, and model-assisted estimation methods. The second part stems from original research conducted by the authors as well as important methodological advances in the field during the past three decades. Topics include calibration weighting methods, regression analysis and survey weighted estimating equation (EE) theory, longitudinal surveys and generalized estimating equations (GEE) analysis, variance estimation and resampling techniques, empirical likelihood methods for complex surveys, handling missing data and non-response, and Bayesian inference for survey data. The third part provides guidance and tools on practical aspects of large-scale surveys, such as training and quality control, frame construction, choices of survey designs, strategies for reducing non-response, and weight calculation. These procedures are illustrated through real-world surveys. Several specialized topics are also discussed in detail, including household surveys, telephone and web surveys, natural resource inventory surveys, adaptive and network surveys, dual-frame and multiple frame surveys, and analysis of non-probability survey samples. This book is a self-contained introduction to survey sampling that provides a strong theoretical base with coverage of current research trends and pragmatic guidance and tools for conducting surveys.

Download or read book Empirical Likelihood Method in Survival Analysis written by Mai Zhou and published by CRC Press. This book was released on 2015-06-17 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical Likelihood Method in Survival Analysis explains how to use the empirical likelihood method for right censored survival data. The author uses R for calculating empirical likelihood and includes many worked out examples with the associated R code. The datasets and code are available for download on his website and CRAN. The book focuses on all the standard survival analysis topics treated with empirical likelihood, including hazard functions, cumulative distribution functions, analysis of the Cox model, and computation of empirical likelihood for censored data. It also covers semi-parametric accelerated failure time models, the optimality of confidence regions derived from empirical likelihood or plug-in empirical likelihood ratio tests, and several empirical likelihood confidence band results. While survival analysis is a classic area of statistical study, the empirical likelihood methodology has only recently been developed. Until now, just one book was available on empirical likelihood and most statistical software did not include empirical likelihood procedures. Addressing this shortfall, this book provides the functions to calculate the empirical likelihood ratio in survival analysis as well as functions related to the empirical likelihood analysis of the Cox regression model and other hazard regression models.

Download or read book Innovative Strategies Statistical Solutions and Simulations for Modern Clinical Trials written by Mark Chang and published by CRC Press. This book was released on 2019-03-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these strategies are generally being considered on an individual trial basis and not as part of a fully integrated overall development program. Such optimization at the trial level is somewhat near-sighted and does not ensure cost, time, or development efficiency of the overall program. This book seeks to address this imbalance by establishing a statistical framework for overall/global clinical development optimization and providing tactics and techniques to support such optimization, including clinical trial simulations. Provides a statistical framework for achieve global optimization in each phase of the drug development process. Describes specific techniques to support optimization including adaptive designs, precision medicine, survival-endpoints, dose finding and multiple testing. Gives practical approaches to handling missing data in clinical trials using SAS. Looks at key controversial issues from both a clinical and statistical perspective. Presents a generous number of case studies from multiple therapeutic areas that help motivate and illustrate the statistical methods introduced in the book. Puts great emphasis on software implementation of the statistical methods with multiple examples of software code (both SAS and R). It is important for statisticians to possess a deep knowledge of the drug development process beyond statistical considerations. For these reasons, this book incorporates both statistical and "clinical/medical" perspectives.

Download or read book Introduction to Empirical Processes and Semiparametric Inference written by Michael R. Kosorok and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kosorok’s brilliant text provides a self-contained introduction to empirical processes and semiparametric inference. These powerful research techniques are surprisingly useful for developing methods of statistical inference for complex models and in understanding the properties of such methods. This is an authoritative text that covers all the bases, and also a friendly and gradual introduction to the area. The book can be used as research reference and textbook.

Download or read book Empirical Likelihood Methods in Biomedicine and Health written by Albert Vexler and published by CRC Press. This book was released on 2018-09-03 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empirical Likelihood Methods in Biomedicine and Health provides a compendium of nonparametric likelihood statistical techniques in the perspective of health research applications. It includes detailed descriptions of the theoretical underpinnings of recently developed empirical likelihood-based methods. The emphasis throughout is on the application of the methods to the health sciences, with worked examples using real data. Provides a systematic overview of novel empirical likelihood techniques. Presents a good balance of theory, methods, and applications. Features detailed worked examples to illustrate the application of the methods. Includes R code for implementation. The book material is attractive and easily understandable to scientists who are new to the research area and may attract statisticians interested in learning more about advanced nonparametric topics including various modern empirical likelihood methods. The book can be used by graduate students majoring in biostatistics, or in a related field, particularly for those who are interested in nonparametric methods with direct applications in Biomedicine.

Download or read book The Stress strength Model and Its Generalizations written by Samuel Kotz and published by World Scientific. This book was released on 2003 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book presents developments in a remarkable field ofinquiry in statistical/probability theory the stressOCostrengthmodel.Many papers in the field include the enigmatic words"P"("X"Y") or something similar in thetitle."

Download or read book Survey Sampling Theory and Applications written by Raghunath Arnab and published by Academic Press. This book was released on 2017-03-08 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survey Sampling Theory and Applications offers a comprehensive overview of survey sampling, including the basics of sampling theory and practice, as well as research-based topics and examples of emerging trends. The text is useful for basic and advanced survey sampling courses. Many other books available for graduate students do not contain material on recent developments in the area of survey sampling. The book covers a wide spectrum of topics on the subject, including repetitive sampling over two occasions with varying probabilities, ranked set sampling, Fays method for balanced repeated replications, mirror-match bootstrap, and controlled sampling procedures. Many topics discussed here are not available in other text books. In each section, theories are illustrated with numerical examples. At the end of each chapter theoretical as well as numerical exercises are given which can help graduate students. - Covers a wide spectrum of topics on survey sampling and statistics - Serves as an ideal text for graduate students and researchers in survey sampling theory and applications - Contains material on recent developments in survey sampling not covered in other books - Illustrates theories using numerical examples and exercises

Download or read book Independent Component Analysis written by Aapo Hyvärinen and published by John Wiley & Sons. This book was released on 2004-04-05 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to ICA for students and practitioners Independent Component Analysis (ICA) is one of the most exciting new topics in fields such as neural networks, advanced statistics, and signal processing. This is the first book to provide a comprehensive introduction to this new technique complete with the fundamental mathematical background needed to understand and utilize it. It offers a general overview of the basics of ICA, important solutions and algorithms, and in-depth coverage of new applications in image processing, telecommunications, audio signal processing, and more. Independent Component Analysis is divided into four sections that cover: * General mathematical concepts utilized in the book * The basic ICA model and its solution * Various extensions of the basic ICA model * Real-world applications for ICA models Authors Hyvarinen, Karhunen, and Oja are well known for their contributions to the development of ICA and here cover all the relevant theory, new algorithms, and applications in various fields. Researchers, students, and practitioners from a variety of disciplines will find this accessible volume both helpful and informative.

Download or read book Statistical Testing Strategies in the Health Sciences written by Albert Vexler and published by CRC Press. This book was released on 2017-12-19 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making, ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap between theoretical statistical methods and practical procedures applied to the planning and analysis of health-related experiments. The book is organized primarily based on the type of questions to be answered by inference procedures or according to the general type of mathematical derivation. It establishes the theoretical framework for each method, with a substantial amount of chapter notes included for additional reference. It then focuses on the practical application for each concept, providing real-world examples that can be easily implemented using corresponding statistical software code in R and SAS. The book also explains the basic elements and methods for constructing correct and powerful statistical decision-making processes to be adapted for complex statistical applications. With techniques spanning robust statistical methods to more computationally intensive approaches, this book shows how to apply correct and efficient testing mechanisms to various problems encountered in medical and epidemiological studies, including clinical trials. Theoretical statisticians, medical researchers, and other practitioners in epidemiology and clinical research will appreciate the book’s novel theoretical and applied results. The book is also suitable for graduate students in biostatistics, epidemiology, health-related sciences, and areas pertaining to formal decision-making mechanisms.

Download or read book In All Likelihood written by Yudi Pawitan and published by OUP Oxford. This book was released on 2013-01-17 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a course in the theory of statistics this text concentrates on what can be achieved using the likelihood/Fisherian method of taking account of uncertainty when studying a statistical problem. It takes the concept ot the likelihood as providing the best methods for unifying the demands of statistical modelling and the theory of inference. Every likelihood concept is illustrated by realistic examples, which are not compromised by computational problems. Examples range from a simile comparison of two accident rates, to complex studies that require generalised linear or semiparametric modelling. The emphasis is that the likelihood is not simply a device to produce an estimate, but an important tool for modelling. The book generally takes an informal approach, where most important results are established using heuristic arguments and motivated with realistic examples. With the currently available computing power, examples are not contrived to allow a closed analytical solution, and the book can concentrate on the statistical aspects of the data modelling. In addition to classical likelihood theory, the book covers many modern topics such as generalized linear models and mixed models, non parametric smoothing, robustness, the EM algorithm and empirical likelihood.

Download or read book Oxidative Stress and Antioxidant Protection written by Donald Armstrong and published by John Wiley & Sons. This book was released on 2016-04-11 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Download or read book Sums of Independent Random Variables written by V.V. Petrov and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic "Limit Dislribntions fOT slt1ns of Independent Ramdorn Vari ables" by B.V. Gnedenko and A.N. Kolmogorov was published in 1949. Since then the theory of summation of independent variables has devel oped rapidly. Today a summing-up of the studies in this area, and their results, would require many volumes. The monograph by I.A. Ibragi mov and Yu. V. I~innik, "Independent and Stationarily Connected VaTiables", which appeared in 1965, contains an exposition of the contem porary state of the theory of the summation of independent identically distributed random variables. The present book borders on that of Ibragimov and Linnik, sharing only a few common areas. Its main focus is on sums of independent but not necessarily identically distri buted random variables. It nevertheless includes a number of the most recent results relating to sums of independent and identically distributed variables. Together with limit theorems, it presents many probahilistic inequalities for sums of an arbitrary number of independent variables. The last two chapters deal with the laws of large numbers and the law of the iterated logarithm. These questions were not treated in Ibragimov and Linnik; Gnedenko and KolmogoTOv deals only with theorems on the weak law of large numbers. Thus this book may be taken as complementary to the book by Ibragimov and Linnik. I do not, however, assume that the reader is familiar with the latter, nor with the monograph by Gnedenko and Kolmogorov, which has long since become a bibliographical rarity

Download or read book Model based Geostatistics for Global Public Health written by Peter J. Diggle and published by CRC Press. This book was released on 2019-03-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model-based Geostatistics for Global Public Health: Methods and Applications provides an introductory account of model-based geostatistics, its implementation in open-source software and its application in public health research. In the public health problems that are the focus of this book, the authors describe and explain the pattern of spatial variation in a health outcome or exposure measurement of interest. Model-based geostatistics uses explicit probability models and established principles of statistical inference to address questions of this kind. Features: Presents state-of-the-art methods in model-based geostatistics. Discusses the application these methods some of the most challenging global public health problems including disease mapping, exposure mapping and environmental epidemiology. Describes exploratory methods for analysing geostatistical data, including: diagnostic checking of residuals standard linear and generalized linear models; variogram analysis; Gaussian process models and geostatistical design issues. Includes a range of more complex geostatistical problems where research is ongoing. All of the results in the book are reproducible using publicly available R code and data-sets, as well as a dedicated R package. This book has been written to be accessible not only to statisticians but also to students and researchers in the public health sciences. The Authors Peter Diggle is Distinguished University Professor of Statistics in the Faculty of Health and Medicine, Lancaster University. He also holds honorary positions at the Johns Hopkins University School of Public Health, Columbia University International Research Institute for Climate and Society, and Yale University School of Public Health. His research involves the development of statistical methods for analyzing spatial and longitudinal data and their applications in the biomedical and health sciences. Dr Emanuele Giorgi is a Lecturer in Biostatistics and member of the CHICAS research group at Lancaster University, where he formerly obtained a PhD in Statistics and Epidemiology in 2015. His research interests involve the development of novel geostatistical methods for disease mapping, with a special focus on malaria and other tropical diseases. In 2018, Dr Giorgi was awarded the Royal Statistical Society Research Prize "for outstanding published contribution at the interface of statistics and epidemiology." He is also the lead developer of PrevMap, an R package where all the methodology found in this book has been implemented.

Download or read book An Information Theoretic Approach to Econometrics written by George G. Judge and published by Cambridge University Press. This book was released on 2011-12-12 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to provide the reader with a firm conceptual and empirical understanding of basic information-theoretic econometric models and methods. Because most data are observational, practitioners work with indirect noisy observations and ill-posed econometric models in the form of stochastic inverse problems. Consequently, traditional econometric methods in many cases are not applicable for answering many of the quantitative questions that analysts wish to ask. After initial chapters deal with parametric and semiparametric linear probability models, the focus turns to solving nonparametric stochastic inverse problems. In succeeding chapters, a family of power divergence measure-likelihood functions are introduced for a range of traditional and nontraditional econometric-model problems. Finally, within either an empirical maximum likelihood or loss context, Ron C. Mittelhammer and George G. Judge suggest a basis for choosing a member of the divergence family.