Download or read book The Troubled Dream of Genetic Medicine written by Keith Wailoo and published by JHU Press. This book was released on 2006-05-29 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the History of Science category of the Professional and Scholarly Publishing Awards given by the Association of American Publishers Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a "Caucasian" disease; and sickle cell disease, widely associated with African Americans. In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these diseases—fraught with ethnic and racial meanings for many Americans—became objects of biological fascination and crucibles of social debate. Peering behind the headlines of breakthrough treatments and coming cures, they tell a complex story: about different kinds of suffering and faith, about unequal access to the promises and perils of modern medicine, and about how Americans consume innovation and how they come to believe in, or resist, the notion of imminent medical breakthroughs. With Tay-Sachs, cystic fibrosis, and sickle cell disease as a powerful backdrop, the authors provide a glimpse into a diverse America where racial ideologies, cultural politics, and conflicting beliefs about the power of genetics shape disparate health care expectations and experiences.
Download or read book The Troubled Dream of Genetic Medicine written by Keith Wailoo and published by Johns Hopkins University Press. This book was released on 2006-04-20 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Tay-Sachs, cystic fibrosis, and sickle cell disease as a powerful backdrop, the authors provide a glimpse into a diverse America where racial ideologies, cultural politics, and conflicting beliefs about the power of genetics shape disparate health care expectations and experiences.
Download or read book The New Genetic Medicine written by Thomas Anthony Shannon and published by Rowman & Littlefield. This book was released on 2003 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1970s, the interrelated areas of medical genetics and biotechnology have developed dramatically and afforded increased control over the design of living organisms. From the very beginning, controversies over these techniques and their applications to plants, animals, and humans have raged in many disciplines--including science, philosophy, ethics, and religion. This book brings together the seminal essays of two leading Catholic moral theologians--Thomas Shannon and James Walter--in an effort to identify the key ethical and theological questions raised by the new genetic medicine. What is unique about this book is that it specifically and directly brings modern genetics and the Roman Catholic theological and ethical tradition into dialogue. While the authors argue that the Catholic tradition has much to offer in putting this current scientific revolution into perspective, they well understand the need to avoid merely repeating the tradition in favor of bringing the best of the tradition to bear on the precise questions posed by modern genetic technology.
Download or read book Life Histories of Genetic Disease written by Andrew J. Hogan and published by Johns Hopkins University Press+ORM. This book was released on 2016-10-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A richly detailed history that “uncovers the challenges and limitations of our increasing reliance on genetic data in medical decision making” (Shobita Parthasarathy, author of Building Genetic Medicine). Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing expectant parents to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In this book, Andrew J. Hogan explores how various diseases were “made genetic” after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly “big data”–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation. Hogan critiques the modern ideology of genetic prevention, which suggests all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies offer whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.
Download or read book The Goals of Medicine written by Mark J. Hanson and published by Georgetown University Press. This book was released on 2000-10-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Debates over health care have focused for so long on economics that the proper goals for medicine seem to be taken for granted; yet problems in health care stem as much from a lack of agreement about the goals and priorities of medicine as from the way systems function. This book asks basic questions about the purposes and ends of medicine and shows that the answers have practical implications for future health care delivery, medical research, and the education of medical students. The Hastings Center coordinated teams of physicians, nurses, public health experts, philosophers, theologians, politicians, health care administrators, social workers, and lawyers in fourteen countries to explore these issues. In this volume, they articulate four basic goals of medicine — prevention of disease, relief of suffering, care of the ill, and avoidance of premature death — and examine them in light of the cultural, political, and economic pressures under which medicine functions. In reporting these findings, the contributors touch on a wide range of diverse issues such as genetic technology, Chinese medicine, care of the elderly, and prevention and public health. The Goals of Medicine clearly demonstrates the importance of clarifying the purposes of medicine before attempting to change the economic and organizational systems. It warns that without such examination, any reform efforts may be fruitless.
Download or read book The PKU Paradox written by Diane B. Paul and published by JHU Press. This book was released on 2013-12 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did a disease of marginal public health significance acquire paradigmatic status in public health and genetics? In a lifetime of practice, most physicians will never encounter a single case of PKU. Yet every physician in the industrialized world learns about the disease in medical school and, since the early 1960s, the newborn heel stick test for PKU has been mandatory in many countries. Diane B. Paul and Jeffrey P. Brosco’s beautifully written book explains this paradox. PKU (phenylketonuria) is a genetic disorder that causes severe cognitive impairment if it is not detected and treated with a strict and difficult diet. Programs to detect PKU and start treatment early are deservedly considered a public health success story. Some have traded on this success to urge expanded newborn screening, defend basic research in genetics, and confront proponents of genetic determinism. In this context, treatment for PKU is typically represented as a simple matter of adhering to a low-phenylalanine diet. In reality, the challenges of living with PKU are daunting. In this first general history of PKU, a historian and a pediatrician explore how a rare genetic disease became the object of an unprecedented system for routine testing. The PKU Paradox is informed by interviews with scientists, clinicians, policymakers, and individuals who live with the disease. The questions it raises touch on ongoing controversies about newborn screening and what happens to blood samples collected at birth.
Download or read book Pain written by Keith Wailoo and published by JHU Press. This book was released on 2014-05-15 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain touches sensitive nerves in American liberalism, conservatism, and political life. In this history of American political culture, Keith Wailoo examines how pain has defined the line between liberals and conservatives from just after World War II to the present. From disabling pain to end-of-life pain to fetal pain, the battle over whose pain is real and who deserves relief has created stark ideological divisions at the bedside, in politics, and in the courts. Beginning with the return of soldiers after World War II and fierce medical and political disagreements about whether pain constitutes a true disability, Wailoo explores the 1960s rise of an expansive liberal pain standard along with the emerging conviction that subjective pain was real, disabling, and compensable. These concepts were attacked during the Reagan era, when a conservative backlash led to diminished disability aid and an expanding role of courts as arbiters in the politicized struggle to define pain. New fronts in pain politics opened nationwide as advocates for death with dignity insisted that end-of-life pain warranted full relief, while the religious right mobilized around fetal pain. The book ends with the 2003 OxyContin arrest of conservative talk show host Rush Limbaugh, a cautionary tale about deregulation and the widening gaps between the overmedicated and the undertreated.
Download or read book Dying in the City of the Blues written by Keith Wailoo and published by UNC Press Books. This book was released on 2014-06-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book chronicles the history of sickle cell anemia in the United States, tracing its transformation from an "invisible" malady to a powerful, yet contested, cultural symbol of African American pain and suffering. Set in Memphis, home of one of the nation's first sickle cell clinics, Dying in the City of the Blues reveals how the recognition, treatment, social understanding, and symbolism of the disease evolved in the twentieth century, shaped by the politics of race, region, health care, and biomedicine. Using medical journals, patients' accounts, black newspapers, blues lyrics, and many other sources, Keith Wailoo follows the disease and its sufferers from the early days of obscurity before sickle cell's "discovery" by Western medicine; through its rise to clinical, scientific, and social prominence in the 1950s; to its politicization in the 1970s and 1980s. Looking forward, he considers the consequences of managed care on the politics of disease in the twenty-first century. A rich and multilayered narrative, Dying in the City of the Blues offers valuable new insight into the African American experience, the impact of race relations and ideologies on health care, and the politics of science, medicine, and disease.
Download or read book Our Present Complaint written by Charles E. Rosenberg and published by JHU Press. This book was released on 2007-12-26 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time when clinical care and biomedical research generate as much angst as they offer cures, this volume provides valuable insight into how the practice of medicine has evolved, where it is going, and how lessons from history can improve its prognosis.--Thomas S. Huddle, M.D., Ph.D. "Journal of the History of Medicine"
Download or read book The Troubled Helix written by Theresa Marteau and published by Cambridge University Press. This book was released on 1996 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This wide ranging and compelling account surveys the exciting opportunities and difficult problems which arise from the new human genetics. The availability of increasingly sophisticated information on our genetic make-up presents individuals, and society as a whole, with difficult decisions. Although it is hoped that these advances will ultimately lead the way to the effective treatment and screening for all diseases with a genetic component, at present many individuals are 'condemned' to a life sentence, in the knowledge that they have or will develop an incurable genetic disease.
Download or read book Three Shots at Prevention written by Keith Wailoo and published by JHU Press. This book was released on 2010-10-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2007, Texas governor Rick Perry issued an executive order requiring that all females entering sixth grade be vaccinated against the human papillomavirus (HPV), igniting national debate that echoed arguments heard across the globe over public policy, sexual health, and the politics of vaccination. Three Shots at Prevention explores the contentious disputes surrounding the controversial vaccine intended to protect against HPV, the most common sexually transmitted infection. When the HPV vaccine first came to the market in 2006, religious conservatives decried the government's approval of the vaccine as implicitly sanctioning teen sex and encouraging promiscuity while advocates applauded its potential to prevent 4,000 cervical cancer deaths in the United States each year. Families worried that laws requiring vaccination reached too far into their private lives. Public health officials wrestled with concerns over whether the drug was too new to be required and whether opposition to it could endanger support for other, widely accepted vaccinations. Many people questioned the aggressive marketing campaigns of the vaccine's creator, Merck & Co. And, since HPV causes cancers of the cervix, vulva, vagina, penis, and anus, why was the vaccine recommended only for females? What did this reveal about gender and sexual politics in the United States? With hundreds of thousands of HPV-related cancer deaths worldwide, how did similar national debates in Europe and the developing world shape the global possibilities of cancer prevention? This volume provides insight into the deep moral, ethical, and scientific questions that must be addressed when sexual and social politics confront public health initiatives in the United States and around the world.
Download or read book How Cancer Crossed the Color Line written by Keith Wailoo and published by Oxford University Press. This book was released on 2011-02-04 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the course of the 20th century, cancer went from being perceived as a white woman's nemesis to a "democratic disease" to a fearsome threat in communities of color. Drawing on film and fiction, on medical and epidemiological evidence, and on patients' accounts, Keith Wailoo tracks this transformation in cancer awareness, revealing how not only awareness, but cancer prevention, treatment, and survival have all been refracted through the lens of race.Spanning more than a century, the book offers a sweeping account of the forces that simultaneously defined cancer as an intensely individualized and personal experience linked to whites, often categorizing people across the color line as racial types lacking similar personal dimensions. Wailoo describes how theories of risk evolved with changes in women's roles, with African-American and new immigrant migration trends, with the growth of federal cancer surveillance, and with diagnostic advances, racial protest, and contemporary health activism. The book examines such powerful and transformative social developments as the mass black migration from rural south to urban north in the 1920s and 1930s, the World War II experience at home and on the war front, and the quest for civil rights and equality in health in the 1950s and '60s. It also explores recent controversies that illuminate the diversity of cancer challenges in America, such as the high cancer rates among privileged women in Marin County, California, the heavy toll of prostate cancer among black men, and the questions about why Vietnamese-American women's cervical cancer rates are so high.A pioneering study, How Cancer Crossed the Color Line gracefully documents how race and gender became central motifs in the birth of cancer awareness, how patterns and perceptions changed over time, and how the "war on cancer" continues to be waged along the color line.
Download or read book An Anthropology of Biomedicine written by Margaret Lock and published by John Wiley & Sons. This book was released on 2010-04-26 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Anthropology of Biomedicine is an exciting new introduction to biomedicine and its global implications. Focusing on the ways in which the application of biomedical technologies bring about radical changes to societies at large, cultural anthropologist Margaret Lock and her co-author physician and medical anthropologist Vinh-Kim Nguyen develop and integrate the thesis that the human body in health and illness is the elusive product of nature and culture that refuses to be pinned down. Introduces biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics Develops and integrates an original theory: that the human body in health and illness is not an ontological given but a moveable, malleable entity Makes extensive use of historical and contemporary ethnographic materials around the globe to illustrate the importance of this methodological approach Integrates key new research data with more classical material, covering the management of epidemics, famines, fertility and birth, by military doctors from colonial times on Uses numerous case studies to illustrate concepts such as the global commodification of human bodies and body parts, modern forms of population, and the extension of biomedical technologies into domestic and intimate domains Winner of the 2010 Prose Award for Archaeology and Anthropology
Download or read book Genetic Medicine written by Karl H. Muench and published by McGraw-Hill/Appleton & Lange. This book was released on 1987-12-01 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Anthropology of Biomedicine written by Margaret M. Lock and published by John Wiley & Sons. This book was released on 2018-03-20 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fully revised and updated second edition of An Anthropology of Biomedicine, authors Lock and Nguyen introduce biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics. Drawing on historical and ethnographic work, the book critiques the assumption made by the biological sciences of a universal human body that can be uniformly standardized. It focuses on the ways in which the application of biomedical technologies brings about radical changes to societies at large based on socioeconomic inequalities and ethical disputes, and develops and integrates the theory that the human body in health and illness is not an ontological given but a moveable, malleable entity. This second edition includes new chapters on: microbiology and the microbiome; global health; and, the self as a socio-technical system. In addition, all chapters have been comprehensively revised to take account of developments from within this fast-paced field, in the intervening years between publications. References and figures have also been updated throughout. This highly-regarded and award-winning textbook (Winner of the 2010 Prose Award for Archaeology and Anthropology) retains the character and features of the previous edition. Its coverage remains broad, including discussion of: biomedical technologies in practice; anthropologies of medicine; biology and human experiments; infertility and assisted reproduction; genomics, epigenomics, and uncertain futures; and molecularizing racial difference, ensuring it remains the essential text for students of anthropology, medical anthropology as well as public and global health.
Download or read book Pushing Cool written by Keith Wailoo and published by University of Chicago Press. This book was released on 2021-11-02 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spanning a century, Pushing Cool reveals how the twin deceptions of health and Black affinity for menthol were crafted—and how the industry’s disturbingly powerful narrative has endured to this day. Police put Eric Garner in a fatal chokehold for selling cigarettes on a New York City street corner. George Floyd was killed by police outside a store in Minneapolis known as “the best place to buy menthols.” Black smokers overwhelmingly prefer menthol brands such as Kool, Salem, and Newport. All of this is no coincidence. The disproportionate Black deaths and cries of “I can’t breathe” that ring out in our era—because of police violence, COVID-19, or menthol smoking—are intimately connected to a post-1960s history of race and exploitation. In Pushing Cool, Keith Wailoo tells the intricate and poignant story of menthol cigarettes for the first time. He pulls back the curtain to reveal the hidden persuaders who shaped menthol buying habits and racial markets across America: the world of tobacco marketers, consultants, psychologists, and social scientists, as well as Black lawmakers and civic groups including the NAACP. Today most Black smokers buy menthols, and calls to prohibit their circulation hinge on a history of the industry’s targeted racial marketing. In 2009, when Congress banned flavored cigarettes as criminal enticements to encourage youth smoking, menthol cigarettes were also slated to be banned. Through a detailed study of internal tobacco industry documents, Wailoo exposes why they weren’t and how they remain so popular with Black smokers.
Download or read book Drawing Blood written by Keith Wailoo and published by JHU Press. This book was released on 2002-10-15 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: How physicians in this century wielded medical technology to define disease, carve out medical specialties, and shape political agendas. Winner of the American Public Health Association Arthur Viseltear Prize In Drawing Blood, medical historian Keith Wailoo uses the story of blood diseases to explain how physicians in this century wielded medical technology to define disease, carve out medical specialties, and shape political agendas. As Wailoo's account makes clear, the seemingly straightforward process of identifying disease is invariably influenced by personal, professional, and social factors—and as a result produces not only clarity and precision but also bias and outright error. Drawing Blood reveals the ways in which physicians and patients as well as the diseases themselves are simultaneously shaping and being shaped by technology, medical professionalization, and society at large. This thought-provoking cultural history of disease, medicine, and technology offers an important perspective for current discussions of HIV and AIDS, genetic blood testing, prostate-specific antigen, and other important issues in an age of technological medicine. "Makes clear that the high stakes involved in medical technology are not just financial, but moral and far reaching. They have been harnessed to describe clinical phenomena and to reflect social and cultural realities that influence not only medical treatment but self-identity, power, and authority."—Susan E. Lederer, H-Net Humanities & Social Sciences On Line "Wailoo's masterful study of hematology and its disease discourse is a model of interdisciplinarity, combining cultural analysis, social history, and the history of medical ideas and technology to produce a complex narrative of disease definition, diagnosis, and treatment . . . He reminds us that medical technology is a neutral artifact of history. It can be, and has been, used to clarify and to cloud the understanding of disease, and it has the potential both to constrain and to emancipate its subjects."—Regina Morantz-Sanchez, Journal of Interdisciplinary History
