Download or read book The Toxicology of Aflatoxins written by David L. Eaton and published by Elsevier. This book was released on 2013-10-22 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins, natural fungal toxins found in foods and animal feeds, have great public health significance. This book presents the basic and applied toxicology of aflatoxins, including analytical identification, agricultural and veterinary implications, toxicology and carcinogenesis in humans, and economic and regulatory problems associated with aflatoxin contamination and control. Molecular mechanisms of aflatoxin toxicity Analytical issues in sampling and analysis Regulatory and economic issues associated with aflatoxin contamination of food and feed Presentation of human and animal toxicology, veterinary, and agricultural issues related to aflatoxin contamination

Download or read book Aflatoxins in Food written by Khalid Rehman Hakeem and published by Springer Nature. This book was released on 2022-01-13 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are the metabolites of fungus and are reported to contaminate nearly 25% of the food produced worldwide. The mycotoxins of most significance are the aflatoxins due to their severe health implications and their prevalence in food commodities on a larger scale. Aflatoxins are produced by certain species of fungi the most prominent among which are Aspergillus flavus, A. parasiticus and A. nominous. Food commodities of African and South Asian countries are especially reported to have aflatoxins well beyond the allowable limits but due to the global trade of food commodities developed countries are also prone towards the perils of aflatoxins. Moreover, climate changes may have a substantial impact on the distribution and global prevalence of aflatoxins in the near future. The International Agency for Research on Cancer (IARC) has classified the aflatoxins as group 1 category carcinogen. Aflatoxins are also reported as teratogenic, mutagenic, growth retardant, immunosuppressant and may also cause nervous system and reproductive system disorders. Preventive approaches involving good manufacturing from “farm to fork” are the major focus of the current food industry. The aim of our book is to provide readers with the most recent data and up-to-date studies from aflatoxins research, with specific focuses on (i) the impact of aflatoxins on human health, (ii) new approaches by the researchers from different parts of the world to degrade aflatoxins and (iii) potential preventive approaches that can significantly lessen the burden of aflatoxins in food products

Download or read book Aflatoxin B1 Occurrence Detection and Toxicological Effects written by and published by BoD – Books on Demand. This book was released on 2020-06-03 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 11 chapters, divided into four parts. The chapters are written by experts in the field of aflatoxins. Select topics are presented here to provide a snapshot of current understanding of the occurrence and metabolism of aflatoxin B1, the contamination, exposure, and detection of aflatoxin B1, and the toxicological effects and detoxification of aflatoxin. The book is intended for students and scientists working in the field of aflatoxins.

Download or read book Aflatoxins written by Mehdi Razzaghi-Abyaneh and published by BoD – Books on Demand. This book was released on 2013-01-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is broadly divided into five sections and 17 chapters, highlighting recent advances in aflatoxin research from epidemiology to molecular genomics and control measures, biocontrol approaches, modern analytical techniques, economic concerns and underlying mechanisms of contamination processes. This book will update readers on several cutting-edge aspects of aflatoxins research with useful up-to-date information for mycologists, toxicologists, microbiologists, agriculture scientists, plant pathologists and pharmacologists, who may be interest to understanding of the impact, significance and recent advances within the field of of aflatoxins with a focus on control strategy.

Download or read book Aflatoxin written by Lukman Abdulra'Uf and published by BoD – Books on Demand. This book was released on 2017-08-30 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins are a group of highly toxic and carcinogenic substances, which occur naturally, and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of the fungi Aspergillus flavus and A. parasiticus and the less common A. nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to the chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated especially in food and feed samples. Therefore, their accurate identification and determination remain a Herculean task due to their presence in complex food matrices. The great public concern and the strict legislation incited the development of reliable, specific, selective, and sensitive analytical methods for pesticide monitoring that are discussed in this book.

Download or read book Handbook of Toxicologic Pathology written by Wanda M. Haschek and published by San Diego : Academic Press. This book was released on 2002 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury.-

Download or read book Aflatoxins Human Health written by Ivana Dvorackova and published by CRC Press. This book was released on 1989-12-21 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date reference includes the most recent available data and detailed case studies concerning the potential health risks of aflatoxin in the human population. It covers everything from acute toxic effects of aflatoxin in men to original observations concerning occupational health hazards due to aflatoxin exposure via the respiratory tract.

Download or read book Toxicology of Aflatoxins written by D. Yourtee and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.

Download or read book Veterinary Toxicology written by Ramesh C Gupta and published by Elsevier. This book was released on 2011-04-28 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Download or read book Nanomycotoxicology written by Mahendra Rai and published by Academic Press. This book was released on 2019-08-24 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge. - Discusses the role of nanotechnology in mycotoxicology - Explores the application of nanomaterials for detection of mycotoxins - Covers the role of nanotechnology in the management of mycotoxins and mycotoxigenic fungi

Download or read book Aflatoxins written by Lukman Abdulra`uf and published by BoD – Books on Demand. This book was released on 2022-02-09 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins are a group of highly toxic and carcinogenic substances that occur naturally and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of fungi Aspergillus flavus and Aspergillus parasiticus as well as the less common Aspergillus nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated, especially in food and feed samples. Therefore, their accurate identification and determination remain a herculean task due to their presence in the complex food matrix. The great public concern and the strict legislation incited the development of sensitive analytical methods that are discussed in this book.

Download or read book The mycotoxin factbook written by D. Barug and published by BRILL. This book was released on 2023-08-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Mycotoxins are poisonous chemical compounds produced by certain fungi. There are many such compounds, but only a few of them are regularly found in food and animal feedstuffs. Nevertheless, those that do occur in food and feed have great significance in the health of humans and livestock. The effects of some mycotoxins are acute, with symptoms of severe illness appearing very quickly. Other mycotoxins have longer term chronic or cumulative effects on health, including the induction of cancers and immune deficiency. Information about mycotoxins is far from complete, but enough is known to identify them as a serious problem in many parts of the world, causing significant economic losses in addition to their negative health effects. 'The mycotoxin factbook' is aimed at the latest developments to combat the mycotoxin problem. The book contains the peer-reviewed papers of the third conference of the World Mycotoxin Forum. The various chapters focus on mycotoxin food and feed risks in the context of human nutrition and animal feeding. Topics dealt with in 'The mycotoxin factbook' are: - Regulatory issues, international developments and the impact on worldtrade - The latest information on major mycotoxins and emerging problems in the food chain - The impact of mycotoxins in the feed chain - New developments in mycotoxin prevention - Trends in mycotoxin analysis 'The mycotoxin factbook' is a valuable resource for researchers and professionals from the food and feed industry as well as from the scientific community. This book is an ideal supplement to 'Meeting the mycotoxin menace' as published in 2004."

Download or read book Mycotoxins and Food Safety written by Jonathan W. DeVries and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins, from the Greek "mukes" referring to fungi or slime molds and toxin from the Latin "toxicum" referencing a poison for arrows, have earned their reputation for being potentially deleterious to the health and well being of a consuming organism, whether it be animal or human. Unfortunately, mycotoxins are a ubiquitous factor in the natural life cycle of food producing plants. As such, control of the potential impact of mycotoxins on food safety relies heavily upon accurate analysis and surveys followed by commodity segregation and restricted use or decontamination through processing. The purpose of this book is to provide the most comprehensive and current information on the topic of mycotoxins and assuring food safety. Chapters represented in the book reflect such diverse topics ranging from occurrence and impact, analysis, reduction through processing and plant breeding, toxicology and safety assessments to regulatory perspectives. Authors represent a range of international perspectives.

Download or read book Mycotoxins in Food Feed and Bioweapons written by Mahendra Rai and published by Springer Science & Business Media. This book was released on 2009-10-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are made by different biosynthetic pathways, and they have an extremely wide range of pharmacological effects. This book will update readers on several cutting-edge aspects of mycotoxin research, including topics such as: new analytical methods for detection; the adoption of an ancient Mexican process for detoxification of aflatoxins; mycotoxin management in Ireland, Lithuania and South America; mycotoxin reduction through plant breeding and integrated management practices; and natural aflatoxin inhibitors from medicinal plants. Further contributions examine ochratoxins, selected trichothecenes, zearalenone, and aflatoxin-like gene clusters, as well as sclerotial development in Aspergillus flavus and A. parasiticus. Of particular interest are the chapters on the potential use of mycotoxins as bioweapons. This book will stimulate new thinking on the need to develop therapeutic as well as preventative interventions to reduce the toxicological threat of mycotoxins.

Download or read book Aflatoxins written by Adina G. Faulkner and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in understanding the biology of Aspergillus has greatly improved with the new techniques in genome sequencing and the developed molecular tools that enable rapid genetic analysis of individual genes. Particularly, the genetics of aflatoxin synthesis is regarded as a model to gain insight into fungal secondary metabolism. This compilation discusses topics that include the prevalence of aflatoxin B1 in cereals; contamination exposure, toxicology and control of aflatoxins in food and feed; immunosuppressive actions of aflatoxin; hazards and regulations; toxicological effects, risk assessment and legislation for aflatoxins; and the threat aflatoxins have on the economy and health.

Download or read book Aflatoxins written by John Godfrey Heathcote and published by Elsevier Science & Technology. This book was released on 1978 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The toxic products from moulds, mycotoxins, are a serious and environmental hazard. They cannot be entirely eliminated. Study of fungal toxins began with the discovery of Aspergillus flavus (parasiticies). Naturally occuring aflatoxins are found in groundnuts, cereals, cotton-seed, and meat and dairy products. The toxins may be synthetically produced. The chemistry and biological assay of toxins are discussed. The toxins produce tumors and biochemically affect nucleic acid and protein synthesis. Control of aflatoxins is possible through mould prevention by control of crop contamination, harvest precautions, and screening. Foods may be detoxified by: 1) removing toxin by extraction; 2) destruction of toxin in situ through heat, radiation, biological degradation, or chemical inactivition. The simplest, most cost-effective method of preventing aflatoxins is by preventative use of good, agricultural methods.