Download or read book The Physiology of Synapses written by John Carew Eccles and published by Academic Press. This book was released on 2013-10-22 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.
Download or read book The Synapse Sequence written by Daniel Godfrey and published by Titan Books (US, CA). This book was released on 2018-06-19 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new thrilling sci-fi novel from the author of New Pompeii and Empire of Time In a future London, humans are watched over by AIs and served by bots. But now that justice and jobs are meted out by algorithm, inequality blooms, and protest is brutally silenced. Anna Glover may be the most hated woman in the troubled city - the media's scapegoat for an unpopular war. Now she hides from the public eye, investigating neglected cases by using the mind-invading technology of the synapse sequencer to enter witnesses' memories. When a PI brings her a new high-stakes case, Anna sees a chance for atonement. But soon she is drawn into a plot that threatens to upend her hard-won anonymity and put everyone in danger - even those she hopes to save.
Download or read book Synapses written by W. Maxwell Cowan and published by JHU Press. This book was released on 2003 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: "For both seasoned neurobiologists and interested newcomers to the field, this book is a worthwhile introduction to the wonders of synapses and the many opportunities for future study that they offer." -- "Science"
Download or read book Structural and Functional Organization of the Synapse written by Johannes W. Hell and published by Springer Science & Business Media. This book was released on 2008-06-25 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.
Download or read book History of the Synapse written by Max R. Bennett and published by CRC Press. This book was released on 2003-09-02 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.
Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Download or read book Nerve Endings written by Richard L. Rapport and published by W. W. Norton & Company. This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two Doctors, the Spaniard Cajal and the Italian Golgi, were racing against each other to find out what brain cells looked like and how they managed to communicate with one another.
Download or read book Synapse written by Steven James and published by HarperChristian + ORM. This book was released on 2019-10-08 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years in the future, when AI is so advanced that humans live side by side with cognizant humanoid robots called Artificials, Kestrel Hathaway must come to terms not just with what machines?know,?but with what they?believe. Soon after experiencing a personal tragedy, Kestrel witnesses a terrorist attack on a nearby artificial factory and is drawn into a world of conspiracies and lies that she and Jordan, her Artificial, have to untangle. With a second, more brutal attack looming on the horizon, their best chance of stopping it is teaming up with federal counterterrorism agent Nick Vernon. But the clock is ticking—and all the while, Jordan is asking questions Artificials were never meant to ask. Deftly weaving suspense and intrigue into a rich, resonant tale that explores faith and what it really means to be human, Steven James offers us a glimpse into the future—and into our own hearts. Synapse?is an unforgettable, gripping story of dreams shattered, truth revealed, and hope reborn. Praise for?Synapse: “Perfectly timed and thought-provoking,?Synapse?is a smart, intense thriller that keeps the suspense?building until the final page. Steven James once again delivers a perfect amalgam of character and?plot, totally immersing the reader in an irresistible narrative.” —Simon Gervais, international bestselling author of?Hunt Them Down “Next-level suspense that keeps the pages turning, combined with next-level writing on par?with the great literary masters . . .?Synapse?is not merely a thriller you should read—as 5G?approaches and advances in AI snowball, it is the thriller you can’t afford?not to.” —James R. Hannibal, award-winning author of?The Gryphon Heist
Download or read book Neuronal Dynamics written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2014-07-24 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
Download or read book Synapse Development and Maturation written by Pasko Rakic and published by Academic Press. This book was released on 2020-05-29 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity
Download or read book Synaptic Transmission written by Stephen D. Meriney and published by Academic Press. This book was released on 2019-06-12 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic
Download or read book Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.
Download or read book From Symptom to Synapse written by Jan Mohlman and published by Routledge. This book was released on 2015-01-30 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume bridges the gap between basic and applied science in understanding the nature and treatment of psychiatric disorders and mental health problems. Topics such as brain imaging, physiological indices of emotion, cognitive enhancement strategies, neuropsychological and cognitive training, and related techniques as tools for increasing our understanding of anxiety, depression, addictions, schizophrenia, ADHD, and other disorders are emphasized. Mental health professionals will learn how to integrate a neurocognitive perspective into their clinical research and practice of psychotherapy.
Download or read book Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability written by Carlo Sala and published by Academic Press. This book was released on 2016-04-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture
Download or read book Synapse Development written by Alexandros Poulopoulos and published by Humana. This book was released on 2016-12-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume collects protocols for experimentation into how neurons connect to produce the extraordinary functionalities of the nervous system. Contributed by experts and pioneers in their respective techniques, the book covers synapses in the brain and in culture, their constituents, their structures, their dynamics, and the assemblies they form, all in the structure of a laboratory guide. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synapse Development: Methods and Protocols serves as an ideal guide to minimizing the barrier to entry for the integration of new approaches with existing expertise, producing syntheses that will foster novel perspectives on the many ways in which synapses form, transform, and transmit.
Download or read book New Pompeii written by Daniel Godfrey and published by Titan Books (US, CA). This book was released on 2016-06-21 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jurassic Park meets Gladiator in this “irresistibly entertaining” sci-fi adventure set in a world in which technology can transport people from the past to present day (Barnes & Noble Sci-Fi Blog) In the race to control renewable power, an energy giant stumbles on a controversial technology: the ability to transport matter from the deep past. Their biggest secret is New Pompeii, a replica city filled with Romans, pulled through time just before the volcanic eruption. Nick Houghton doesn’t know why he’s been chosen to be the company’s historical advisor. He’s just excited to be there. Until he starts to wonder what happened to his predecessor. Until he realizes that the company has more secrets than even the conspiracy theorists suspect. Until he realizes that they have underestimated their captives.
Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
