Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-19 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-16 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

Download or read book A Funny Thing Happened on the Way to Stockholm written by Robert Lefkowitz and published by Simon and Schuster. This book was released on 2021-02-02 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a days work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists.

Download or read book States and Nature written by Joshua Busby and published by Cambridge University Press. This book was released on 2022-03-24 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Busby explains how climate change can affect security outcomes, including violent conflict and humanitarian emergencies. Through case studies from sub-Saharan Africa, the Middle East, and South Asia, the book develops a novel argument explaining why climate change leads to especially bad security outcomes in some places but not in others.

Download or read book The Atrocity Paradigm written by Claudia Card and published by Oxford University Press. This book was released on 2002-09-12 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: What distinguishes evils from ordinary wrongs? Is hatred a necessarily evil? Are some evils unforgivable? Are there evils we should tolerate? What can make evils hard to recognize? Are evils inevitable? How can we best respond to and live with evils? Claudia Card offers a secular theory of evil that responds to these questions and more. Evils, according to her theory, have two fundamental components. One component is reasonably foreseeable intolerable harm -- harm that makes a life indecent and impossible or that makes a death indecent. The other component is culpable wrongdoing. Atrocities, such as genocides, slavery, war rape, torture, and severe child abuse, are Cards paradigms because in them these key elements are writ large. Atrocities deserve more attention than secular philosophers have so far paid them. They are distinguished from ordinary wrongs not by the psychological states of evildoers but by the seriousness of the harm that is done. Evildoers need not be sadistic:they may simply be negligent or unscrupulous in pursuing their goals. Cards theory represents a compromise between classic utilitarian and stoic alternatives (including Kants theory of radical evil). Utilitarians tend to reduce evils to their harms; Stoics tend to reduce evils to the wickedness of perpetrators: Card accepts neither reduction. She also responds to Nietzsches challenges about the worth of the concept of evil, and she uses her theory to argue that evils are more important than merely unjust inequalities. She applies the theory in explorations of war rape and violence against intimates. She also takes up what Primo Levi called the gray zone, where victims become complicit in perpetrating on others evils that threaten to engulf themselves. While most past accounts of evil have focused on perpetrators, Card begins instead from the position of the victims, but then considers more generally how to respond to -- and live with -- evils, as victims, as perpetrators, and as those who have become both.

Download or read book The Blueprint written by Daniel Rirdan and published by Daniel Rirdan. This book was released on 2012 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: From climate change to land degradation to fossil fuel shortages, we are faced with an impending calamity that threatens to bankrupt the planetary ecosystem and with it much of the manmade world. This book offers a plan that truly goes the distance: a highly detailed, planetary-wide blueprint that lays out a new course for our technological and industrial engines. It calls for sweeping adjustments in the way every person thinks and lives.--Inside front cover.

Download or read book Mobile Virtual Work written by J.H. Erik Andriessen and published by Springer Science & Business Media. This book was released on 2005-12-16 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dear Reader This is a book about mobile virtual work. It aims at clarifying the basic concepts and showing present practices and future challenges. The roots of the book are in the collaboration of few European practitioners and - searchers, who met each other under the umbrella of the Swedish SALTSA programme (see next page) in January 2002 in Stockholm. The group was first called ‘ICT, Mobility and Work Organisation’ but redefined itself quickly as ‘Mobile Virtual Cooperative Work’ group. The change of the name reflects the development of reasoning in the group. We could not find much material on mobile work, certainly not systematic studies, - though a growing interest in mobile technologies and services could be found. Practices of telework and virtual organizations were better known, but we were convinced that the combination with mobile work was so- thing different and new. Our main target became to understand what it was all about. The next step was an expert meeting in October 2004 at Rånäs Castle again in Sweden. A wider group of experts was invited to present their views on mobile virtual work and ideas about book chapters from different perspectives of working life. Some of the expertise could be found through the network of the AMI@Work family created by the New Working En- ronments unit of the European Commission’s Information Society Dir- torate-General. Also close collaboration was developed with the related MOSAIC program.

Download or read book Rethinking Cancer written by Bernhard Strauss and published by MIT Press. This book was released on 2021-04-27 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.

Download or read book String Theory and the Scientific Method written by Richard Dawid and published by Cambridge University Press. This book was released on 2013-05-02 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: String theory has played a highly influential role in theoretical physics for nearly three decades and has substantially altered our view of the elementary building principles of the Universe. However, the theory remains empirically unconfirmed, and is expected to remain so for the foreseeable future. So why do string theorists have such a strong belief in their theory? This book explores this question, offering a novel insight into the nature of theory assessment itself. Dawid approaches the topic from a unique position, having extensive experience in both philosophy and high-energy physics. He argues that string theory is just the most conspicuous example of a number of theories in high-energy physics where non-empirical theory assessment has an important part to play. Aimed at physicists and philosophers of science, the book does not use mathematical formalism and explains most technical terms.

Download or read book Big World Small Planet written by Johan Rockstrom and published by Yale University Press. This book was released on 2015-01-01 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have entered the Anthropocene - the era of massive human impacts on the planet - and the actions of over seven billion residents threaten to destabilize Earth's natural systems, with consequences for human societies. The authors combine the latest science with storytelling and photography to create a new narrative for humanity's future and reject the notion that economic growth and human prosperity can only be achieved at the expense of the environment

Download or read book Encyclopedia of Criminological Theory written by Francis T. Cullen and published by SAGE Publications. This book was released on 2009-12-15 with total page 1241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set is designed to serve as a reference source for anyone interested in the roots of contemporary criminological theory. Drawing together a team of international scholars, it examines the global landscape of all the key theories and the theorists behind them, presenting them in a context needed to understand their strengths and weaknesses. The work provides essays on cutting-edge research as well as concise, to-the-point definitions of key concepts, ideas, schools, and figures. Topics include contexts and concepts in criminological theory, the social construction of crime, policy implications of theory, diversity and intercultural contexts, conflict theory, rational choice theories, conservative criminology, feminist theory, and more. Key ThemesThe Classical School of CriminologyThe Positivist School of CriminologyEarly American Theories of CrimeBiological and Biosocial Theories of CrimePsychological Theories of CrimeThe Chicago School of CriminologyCultural and Learning Theories of CrimeAnomie and Strain Theories of Crime and DevianceControl Theories of CrimeLabeling and Interactionist Theories of CrimeTheories of the Criminal SanctionConflict, Radical, and Critical Theories of CrimeFeminist and Gender-Specific Theories of CrimeChoice and Opportunity Theories of CrimeMacro-Level/ Community Theories of CrimeLife-Course and Developmental Theories of CrimeIntegrated Theories of CrimeTheories of White-Collar and Corporate CrimeContemporary Gang TheoriesTheories of Prison Behavior and InsurgencyTheories of Fear and Concern About Crime

Download or read book Governing Climate Change written by Andrew Jordan and published by Cambridge University Press. This book was released on 2018-05-03 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Climate change governance is in a state of enormous flux. New and more dynamic forms of governing are appearing around the international climate regime centred on the United Nations Framework Convention on Climate Change (UNFCCC). They appear to be emerging spontaneously from the bottom up, producing a more dispersed pattern of governing, which Nobel Laureate Elinor Ostrom famously described as 'polycentric'. This book brings together contributions from some of the world's foremost experts to provide the first systematic test of the ability of polycentric thinking to explain and enhance societal attempts to govern climate change. It is ideal for researchers in public policy, international relations, environmental science, environmental management, politics, law and public administration. It will also be useful on advanced courses in climate policy and governance, and for practitioners seeking incisive summaries of developments in particular sub-areas and sectors. This title is also available as Open Access on Cambridge Core.

Download or read book Case Theory in Business and Management written by Evert Gummesson and published by SAGE. This book was released on 2017-01-25 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: ′This meticulous book submits research and the research process to deep scrutiny. It debunks the unhelpful dichotomy between quantitative and qualitative research and highlights the great value of multi-method and interactive research, approaches that have greatly deepened our thinking.′ – Professor Adrian Payne, University of New South Wales, Australia / Professor Pennie Frow, University of Sydney Setting out to dispel the argument that case study research lacks the science, theory and therefore validity of other forms of research, Evert Gummesson combines many decades of experience as both a renowned scholar and a reflective practitioner to effectively bridge the divide between case theory and how it is applied in practice. Bringing the fundamental strengths of cases to the fore, Gummesson introduces the ′Case Theory′ concept as an expanded version of case study research which includes both methodology and the types of results that emerge by: Guiding the reader in the theoretical and philosophical underpinning Demonstrating how to translate theory to pertinent research practice that address the real and consequential issues in business and management today. This book will appeal to students, academics and researchers who are interested in the science and philosophy behind case study research as well as the methodology and a thought-provoking read for anyone who wants to be challenged about their belief of case study theory.

Download or read book Future Sea written by Deborah Rowan Wright and published by University of Chicago Press. This book was released on 2020-10-27 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: A counterintuitive and compelling argument that existing laws already protect the entirety of our oceans—and a call to understand and enforce those protections. The world’s oceans face multiple threats: the effects of climate change, pollution, overfishing, plastic waste, and more. Confronted with the immensity of these challenges and of the oceans themselves, we might wonder what more can be done to stop their decline and better protect the sea and marine life. Such widespread environmental threats call for a simple but significant shift in reasoning to bring about long-overdue, elemental change in the way we use ocean resources. In Future Sea, ocean advocate and marine-policy researcher Deborah Rowan Wright provides the tools for that shift. Questioning the underlying philosophy of established ocean conservation approaches, Rowan Wright lays out a radical alternative: a bold and far-reaching strategy of 100 percent ocean protection that would put an end to destructive industrial activities, better safeguard marine biodiversity, and enable ocean wildlife to return and thrive along coasts and in seas around the globe. Future Sea is essentially concerned with the solutions and not the problems. Rowan Wright shines a light on existing international laws intended to keep marine environments safe that could underpin this new strategy. She gathers inspiring stories of communities and countries using ocean resources wisely, as well as of successful conservation projects, to build up a cautiously optimistic picture of the future for our oceans—counteracting all-too-prevalent reports of doom and gloom. A passionate, sweeping, and personal account, Future Sea not only argues for systemic change in how we manage what we do in the sea but also describes steps that anyone, from children to political leaders (or indeed, any reader of the book), can take toward safeguarding the oceans and their extraordinary wildlife.

Download or read book The Third Lens written by Andrew S. Reynolds and published by University of Chicago Press. This book was released on 2018-06-21 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does science aim at providing an account of the world that is literally true or objectively true? Understanding the difference requires paying close attention to metaphor and its role in science. In The Third Lens, Andrew S. Reynolds argues that metaphors, like microscopes and other instruments, are a vital tool in the construction of scientific knowledge and explanations of how the world works. More than just rhetorical devices for conveying difficult ideas, metaphors provide the conceptual means with which scientists interpret and intervene in the world. Reynolds here investigates the role of metaphors in the creation of scientific concepts, theories, and explanations, using cell theory as his primary case study. He explores the history of key metaphors that have informed the field and the experimental, philosophical, and social circumstances under which they have emerged, risen in popularity, and in some cases faded from view. How we think of cells—as chambers, organisms, or even machines—makes a difference to scientific practice. Consequently, an accurate picture of how scientific knowledge is made requires us to understand how the metaphors scientists use—and the social values that often surreptitiously accompany them—influence our understanding of the world, and, ultimately, of ourselves. The influence of metaphor isn’t limited to how we think about cells or proteins: in some cases they can even lead to real material change in the very nature of the thing in question, as scientists use technology to alter the reality to fit the metaphor. Drawing out the implications of science’s reliance upon metaphor, The Third Lens will be of interest to anyone working in the areas of history and philosophy of science, science studies, cell and molecular biology, science education and communication, and metaphor in general.

Download or read book Loving to Survive written by Dee L.R. Graham and published by NYU Press. This book was released on 1995-07-01 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: A selection of insights into the relationship between men and women Have you wondered: Why women are more sympathetic than men toward O. J. Simpson? Why women were no more supportive of the Equal Rights Amendment than men? Why women are no more likely than men to support a female political candidate? Why women are no more likely than men to embrace feminism—a movement by, about, and for women? Why some women stay with men who abuse them? Loving to Survive addresses just these issues and poses a surprising answer. Likening women's situation to that of hostages, Dee L. R. Graham and her co- authors argue that women bond with men and adopt men's perspective in an effort to escape the threat of men's violence against them. Dee Graham's announcement, in 1991, of her research on male-female bonding was immediately followed by a national firestorm of media interest. Her startling and provocative conclusion was covered in dozens of national newspapers and heatedly debated. In Loving to Survive, Graham provides us with a complete account of her remarkable insights into relationships between men and women. In 1973, three women and one man were held hostage in one of the largest banks in Stockholm by two ex-convicts. These two men threatened their lives, but also showed them kindness. Over the course of the long ordeal, the hostages came to identify with their captors, developing an emotional bond with them. They began to perceive the police, their prospective liberators, as their enemies, and their captors as their friends, as a source of security. This seemingly bizarre reaction to captivity, in which the hostages and captors mutually bond to one another, has been documented in other cases as well, and has become widely known as Stockholm Syndrome. The authors of this book take this syndrome as their starting point to develop a new way of looking at male-female relationships. Loving to Survive considers men's violence against women as crucial to understanding women's current psychology. Men's violence creates ever-present, and therefore often unrecognized, terror in women. This terror is often experienced as a fear for any woman of rape by any man or as a fear of making any man angry. They propose that women's current psychology is actually a psychology of women under conditions of captivitythat is, under conditions of terror caused by male violence against women. Therefore, women's responses to men, and to male violence, resemble hostages' responses to captors. Loving to Survive explores women's bonding to men as it relates to men's violence against women. It proposes that, like hostages who work to placate their captors lest they kill them, women work to please men, and from this springs women's femininity. Femininity describes a set of behaviors that please men because they communicate a woman's acceptance of her subordinate status. Thus, feminine behaviors are, in essence, survival strategies. Like hostages who bond to their captors, women bond to men in an effort to survive. This is a book that will forever change the way we look at male-female relationships and women's lives.

Download or read book Adaptation in Metapopulations written by Michael J. Wade and published by University of Chicago Press. This book was released on 2016-05-03 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Across the globe, populations of plants and animals live in clusters, but maintain a connectivity a population of populations. There are naturally occurring metapopulations, such as clusters of groupers spread across coral reefs, and there are metapopulations humans have helped create by fragmenting landscapes: stands of trees separated by roads, prairies separated by agricultural farms. As the dynamics of landscape change have accelerated, and understanding of how metapopulations functions has played a critical role in ecology and evolutionary biology. Adaptation in Metapopulations synthesizes the role of genetic interactions in adaptive evolution and their influence on the effectiveness of different types of selection. Drawing on extensive field work and lab experiments, cohered with a strong conceptual arc, the work also integrates molecular and organismal biology, as Wade explores adaptation at multiple scales, and shows how evolutionary dynamics scale from the gene to the metapopulation. "