Download or read book The Stimulated Brain written by Roi Cohen Kadosh and published by Elsevier. This book was released on 2014-06-01 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in "stimulating their minds by exploring this fascinating field of research. - Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers - The only reference on the market to focus on transcranial electrical stimulation (tES) - Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students - Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available

Download or read book Cognitive Enhancement written by Shira Knafo and published by Academic Press. This book was released on 2014-12-20 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors addresses the gap that exists in research on the topic, gathering multidisciplinary knowledge and tools that help the reader understand the basics of cognitive enhancement. It also provides assistance in designing procedures and pharmacological approaches to further the use of novel cognitive enhancers, a field that offers potential benefit to a variety of populations, including those with neurologic and psychiatric disorders, mild aging-related cognitive impairment, and those who want to improve intellectual performance. The text builds on our knowledge of the molecular/cellular basis of cognitive function, offering the technological developments that may soon enhance cognition. Separate sections cover enhancement drugs, environmental conditions, and genetic factors in terms of both human and animal studies, including both healthy/young and aging/diseased individuals. - Provides a multidisciplinary knowledge, enabling a further understanding of cognitive enhancement - Offers coverage of the pharmacologic, environmental, and genetic factors relevant to the topic - Discusses cognitive enhancement from the perspective of both healthy and diseased or aging populations - Topics are discussed in terms of both human and animal studies

Download or read book The Pleasure Shock written by Lone Frank and published by Penguin. This book was released on 2018-03-20 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The electrifying, forgotten history of Robert Heath's brain pacemaker, investigating the origins and ethics of one of today's most promising medical breakthroughs: deep brain stimulation The technology invented by psychiatrist Robert G. Heath in the 1950s and '60s has been described as among the most controversial experiments in US history. His work was alleged at the time to be part of MKUltra, the CIA's notorious "mind control" project. His research subjects included incarcerated convicts and gay men who wished to be "cured" of their sexual preference. Yet his cutting-edge research and legacy were quickly buried deep in Tulane University's archives. Investigative science journalist Lone Frank now tells the complete sage of this passionate, determined doctor and his groundbreaking neuroscience. More than fifty years after Heath's experiments, this very same treatment is becoming mainstream practice in modern psychiatry for everything from schizophrenia, anorexia, and compulsive behavior to depression, Parkinson's, and even substance addiction. Lone Frank uncovered lost documents and accounts of Heath's trailblazing work. She tracked down surviving colleagues and patients, and she delved into the current support for deep brain stimulation by scientists and patients alike. What has changed? Why do we today unquestioningly embrace this technology as a cure? How do we decide what is a disease of the brain to be cured and what should be allowed to remain unrobed and unprodded? And how do we weigh the decades of criticism against the promise of treatment that could be offered to millions of patients? Elegantly written and deeply fascinating, The Pleasure Shock weaves together biography, scientific history, and medical ethics. It is an adventure into our ever-shifting views of the mind and the fateful power we wield when we tinker with the self.

Download or read book Non Invasive Neuromodulation of the Central Nervous System written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-11-02 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and non-therapeutic applications of non-invasive neuromodulation will continue to expand in coming years, particularly for indications where treatments are currently insufficient, such as drug-resistant depression. Given the growing interest in non-invasive neuromodulation technologies, the Institute of Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop, inviting a range of stakeholders - including developers of devices and new technologies, researchers, clinicians, ethicists, regulators, and payers - to explore the opportunities, challenges, and ethical questions surrounding the development, regulation, and reimbursement of these devices for the treatment of nervous system disorders as well as for non-therapeutic uses, including cognitive and functional enhancement. This report highlights the presentation and discussion of the workshop.

Download or read book Brain Stimulation written by Filippo Agnesi and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic deep brain stimulation (DBS) has become a widely accepted surgical treatment for medication-refractory movement disorders and is under evaluation for a variety of neurological disorders. In order to create opportunities to improve treatment efficacy, streamline parameter selection, and foster new potential applications, it is important to have a clear and comprehensive understanding of how DBS works. Although early hypothesis proposed that high-frequency electrical stimulation inhibited neuronal activity proximal to the active electrode, recent studies have suggested that the output of the stimulated nuclei is paradoxically activated by DBS. Such regular, time-locked output is thought to override the transmission of pathological bursting and oscillatory activity through the stimulated nuclei, as well as inducing synaptic plasticity and network reorganization. This chapter reviews electrophysiological experiments, biochemical analyses, computer modeling and imaging studies positing that, although general principles exist, the therapeutic mechanism(s) of action depend both on the site of stimulation and on the disorder being treated.

Download or read book Brain Stimulation written by Irving Reti and published by John Wiley & Sons. This book was released on 2015-05-11 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brainstimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activity dependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians.

Download or read book Brain Stimulation and Motivation written by Elliot S. Valenstein and published by Scott Foresman. This book was released on 1973 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Brain Stimulation written by David T. Brocker and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation is a remarkable therapy that has mainstreamed electrical stimulation of the brain for the treatment of neurological dysfunction. To appreciate the mechanisms of deep brain stimulation, we need to understand the excitability of neural tissue. Here, we survey the pertinent principles of electrical excitation in the brain. The amount of current delivered and the tissue conductivity together determine the strength and extent of potentials generated by stimulation. The electrode–tissue interface is an important junction where electrical charge carriers in the stimulation hardware are converted to ionic charge carriers in the tissue. Cathodic stimulation tends to depolarize neural elements more easily than anodic stimulation. The current–distance relationship describes how the amount of current needed to excite an axon increases as a function of its distance from the electrode. This relationship also depends on the axon’s diameter because large-diameter axons are excited more easily than small-diameter axons. For a given axon, the strength–duration relationship describes the inverse relationship between threshold current amplitude and pulse duration. Specific stimulation parameters must be considered to avoid stimulation-induced tissue damage. A strong foundation in these principles facilitates understanding of the complex effects of electrical stimulation in the brain.

Download or read book The Stimulated Brain written by Mariska Hendrika Maria Mantione and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Deep Brain Stimulation Management written by William J. Marks, Jr and published by Cambridge University Press. This book was released on 2015-09-03 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.

Download or read book Textbook of Cortical Brain Stimulation written by Sergio Canavero and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-01-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed over the past 25 years, Cortical Brain Stimulation has emerged as a brand new, cutting-edge option for the treatment of intractable neurological and psychiatric disorders. Devoid of the mortality and disabling morbidity that may accompany deep brain stimulation, stimulating the cortex with a minimally invasive surgical approach had initially proved its worth for the treatment of Central and other Neuropathic Pain Syndromes and later for Parkinson Disease, Dystonia, Stroke and Coma rehabilitation, Epilepsy, Depression and Tinnitus. Written by many of the pioneers in the field, this authoritative treatise is a comprehensive presentation - from surgical details, to clinical results and mechanisms of action. It also provides the busy clinician with comparisons with non-invasive cortical stimulation techniques, such as TMS and tDCS. No other book deals with this form of brain stimulation. The clinician will harness the power of this formidable new therapeutic option, which is being further refined with the advent of closed-loop stimulation. Dr Canavero deciphered the genesis of the central pain syndromes, introduced extradural cortical stimulation for Parkinson Disease and the vegetative state and co-introduced extradural cortical stimulation for stroke rehabilitation. He made worldwide news in 2008 for partially restoring consciousness in two vegetative patients, in 2013 for proposing the HEAVEN/GEMINI protocol for human head transplantation and in 2014 for pushing brain stimulation in the setting of criminal psychopathy. His books include: Central Pain Syndrome, Cambridge Univ. Press, 2011 (2nd ed.), Textbook of therapeutic cortical stimulation, Nova Sci, 2009 and two books in Italian on human sexual behavior.

Download or read book Brain Stimulation Therapies for Clinicians written by Edmund S. Higgins and published by American Psychiatric Pub. This book was released on 2019-08-13 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of the state of current practice, this new edition of Brain Stimulation Therapies for Clinicians provides thoroughly updated information on the growing list of electrical stimulation therapies now in use or under study, including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), cortical stimulation (CS), and transcranial direct current stimulation (TDCS), as well as new coverage of promising treatments such as low intensity focused ultrasound pulsation (LIFUP) and temporal interference stimulation (TI). After a brief course on the fundamentals of electricity and a refresher on neuroanatomy, the text explores how electricity works within biological systems before progressing to the chapters on individual therapies, which cover the history and evolution of the treatment, the techniques involved, clinical indications, side effects, and an up-to-date review of the evidence base supporting its use. The book is designed to help the reader cut through the initially daunting "alphabet soup" (e.g., ECT, TMS) by providing a clear and straightforward analysis of the prevailing techniques -- an indispensable resource for both clinicians and patients seeking in-depth knowledge of these acronyms and methods. The book's noteworthy features are many: Refinements in treatment protocols since the last edition are discussed in detail. For example, the sections on ECT cover advances such as focal electrically administered seizure therapy (FEAST) and magnetic seizure therapy (MST), while the TMS chapter covers theta burst and recent approval for obsessive-compulsive disorder. The underlying science is addressed in the initial review of electricity and physics, information that is foundational to these treatment modalities, but that clinicians do not encounter in the medical school curriculum. The section also addresses the parameters for brain stimulation and how to determine the right dose. A separate chapter is devoted to low intensity focused ultrasound pulsations (LIFUP) and temporally interfering (TI) electric fields, emerging treatments that have the potential to noninvasively stimulate focal locations deep in the brain without surgery or the implantation of hardware. The section on using DBS for treatment-resistant Parkinson's disease (PD) is thorough, authoritative, and a boon to clinicians assessing the viability and efficacy of treatment options for their PD patients. The new edition retains the amusing, but always informative sidebars highlighting the history of brain experimentation and applications of brain stimulation techniques Written in a down-to-earth, accessible style by authors at the forefront of progress in the field, Brain Stimulation Therapies for Clinicians is a rigorous, evidence based review of clinical data that focuses on what we know, what we don't know, and the strength of the evidence.

Download or read book Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders written by Bahman Zohuri and published by Academic Press. This book was released on 2022-08-20 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcranial Magnetic and Electrical Brain Stimulation for Neurological Disorders examines the non-invasive application of electrical stimulation of the brain to treat neurological disorders, and to enhance individual/group performance. This volume discusses emerging electro-technologies such as transcranial direct current/alternating current electric fields and pulsed magnetic fields to treat many of these common medical problems. Chapters begin by examining foundations of electromagnetic theory and wave equations that underly these technologies before discussing methods to treat disorders, the impact of technology and mental health and artificial intelligence. Discussing over 40 neurological diseases, this book presents coverage of techniques to treat stroke, epilepsy, Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, depression, schizophrenia, and many other diseases of the nervous system. Compares techniques so users can select ideal methods for their experiment Provides a focused tutorial introduction to core diseases of the nervous system, including stroke, epilepsy, Alzheimer’s, Parkinson’s, head and spinal cord trauma, schizophrenia, and more Covers more than 40 diseases, from foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics and neuroscience Provides walk-through boxes that guide students step-by-step through the experiment

Download or read book Brain Stimulation written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Brain Stimulation and Behavioral Change written by Claudio Lucchiari and published by Frontiers Media SA. This book was released on 2019-05-15 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eBook entitled “Brain Stimulation and Behavioral Change” is a collection of articles about the use of transcranial electric stimulation (tES) to change behaviors and face pathological conditions, to enhance cognition and to explore cerebral functions using safe and non-invasive brain modulation techniques. The tESs include transcranial direct current stimulation (tDCS), transcranial alternate current stimulation (tACS), and, due to the way it induces changes in the brain, Transcranial Magnetic Stimulation (TMS). The use of tES has recently exploded. Certainly, one reason for this explosion of research is that it is a cheap way to change behavior. However, on the other hand, we still know very little about the neural mechanisms that underlie tES. The present eBook includes both original studies and reviews. It covers a wide scope of arguments, including studies aimed at testing the potential ability of tES in mitigating physical and psychiatric symptoms, and to support neurological rehabilitation, enhancing reading abilities, motor abilities, and creativity. Furthermore, some contributions about the role of tES in discovering and mapping the neuro-functional correlates of higher cognitive functions are also included. The common background of the contributions included in the eBook lies in the idea that we need sound scientific evidence about how to move these techniques from labs to real-life contexts. Addressing these issues and understanding the real potentialities of tES in clinical and non-clinical applications require a significant cross-fertilization between disciplines. We hope this eBook will be able to boost the discussion on this vital topic.

Download or read book Electrical Stimulation of the Brain written by Daniel Elvin Sheer and published by . This book was released on 1961 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Transcranial Brain Stimulation written by Carlo Miniussi and published by . This book was released on 2019-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen the introduction and rapid development of non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES). This book reviews these recent advances made in the understanding of brain stimulation techniques. The text presents the wide range of possible brain stimulation applications in combination with neuroimaging and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. With this timely resource, the authors aim to make a substantial impact on many areas of clinical and basic neuroscience.