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Book Chemistry and Biological Activity of Steroids

Download or read book Chemistry and Biological Activity of Steroids written by Jorge António Ribeiro Salvador and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.

Book Anabolic Steroid Abuse

Download or read book Anabolic Steroid Abuse written by Geraline C. Lin and published by DIANE Publishing. This book was released on 1996-07 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the question of whether or not anabolic steroids in themselves possess abuse potential or if they simply play a role in the abuse of other substances. A historical overview of the discovery and development of the drug is provided, plus an evaluation of the drug's performance-enhancing effects. Health risks associated with the abuse of anabolic steroids are covered along with the biological reasons why steroids affect the body the way they do. Behavioral effects are also discussed. Charts, graphs and diagrams.

Book Endocrine Disruption and Human Health

Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Book Principles of Endocrinology and Hormone Action

Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.

Book Psychoneuroendocrinology

    Book Details:
  • Author : Owen M. Wolkowitz
  • Publisher : American Psychiatric Pub
  • Release : 2008-08-13
  • ISBN : 1585627577
  • Pages : 612 pages

Download or read book Psychoneuroendocrinology written by Owen M. Wolkowitz and published by American Psychiatric Pub. This book was released on 2008-08-13 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mind-body connection is one of the hottest topics in medicine today, documented by enormous amounts of data regarding hormone effects on the brain and behavior. Yet it is only now -- with the debut of this thought-provoking volume -- that we find an up-to-date, sophisticated reference that focuses on the clinical relevance of behavioral endocrinology and is written for practicing clinicians and researchers. This wide-ranging volume shows how the principles and emerging findings of psychoneuroendocrinology can inform modern clinical practice and lead to new breakthroughs in future science and practice. Here, leading authorities -- internationally respected researchers and practicing clinicians -- review empirical findings in their areas of expertise, highlight the clinical significance of these findings, and provide, wherever appropriate, clinical guidelines for the management of patients. Beginning with a lively history of psychoneuroendocrinology (including its many false starts), this book continues on to discussions of the hypothalamic-pituitary-adrenal axis hormone system, the gonadal hormone system, and the thyroid hormone system from each of the three paths generally used for psychoneuroendocrinological investigation: Alterations in endogenous hormone levels observed in primary psychiatric illness Psychiatric concomitants or sequelae of hormonal dysregulation in primary endocrinologic illness Behavioral effects of exogenously administered hormones or hormone antagonists (both the study of the side effects of hormonal medications and the use of hormones and hormone antagonists as psychotropic medications) An unmatched diversity of topics reveals the full breadth and depth of this volume: diabetes mellitus, corticosteroid effects on mood and cognition, Cushing's syndrome and Addison's disease, oral contraceptives and estrogen replacement therapy, psychiatric illness associated with the menstrual cycle and perimenopause, postpartum behavioral changes, anabolic/androgenic steroid use, and a thorough review of thyroid function in psychiatric disorders. Particularly fascinating are sections on the role of neuropeptides and hypothalamic-releasing factors in psychiatric illness, the use of laboratory tests and imaging procedures in evaluating hormonal function in psychiatric patients, the place of newer "alternative" hormonal medications such as melatonin and DHEA in therapeutics, and a provocative and compelling final chapter on the role stress plays in precipitating illness. Designed for both clinician and researcher-scientist, this richly informative guide will also prove an invaluable addition to graduate courses in neuroscience, neuroendocrinology, the biological basis of behavior, and consultation psychiatry. Neuroscientists/neurologists, endocrinologists, obstetricians/gynecologists, internists, family practitioners, nurses, and interested laypersons round out the wide audience for this remarkable volume.

Book Handbook of hair in health and disease

Download or read book Handbook of hair in health and disease written by Victor R. Preedy and published by Springer. This book was released on 2012-05-23 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hair is a major component of the body's tissue system that contributes to the individual's make up and confers a large degree of personal identity. Apart from its visible façade, hair also has a functional role. It has an unique structure and complex molecular development. The very nature of hair makes it a suitable marker for the prognosis of disease. Hair can also be used to screen for toxins and changes in the diet. However, there are currently no suitable publications available that describe hair in a rational scientific context. This handbook provides an academic approach to hair in health and disease. Divided into five sections the Handbook of Hair in Health and Disease provides an insight into hair growth and loss, molecular and cellular biology of hair, dietary toxicity and pathological history, diseases and treatments of hair, as well as shampoos and conditioners. Unique features of each chapter in this volume include relevant and useful 'Key facts' which highlight interesting or important findings of the specific subjects and 'Summary points' that will give a clear overview of the subjects treated in each chapter. The Handbook of Hair in Health and Disease will be essential to a variety of users, such as trichologists, doctors and nurses and all those interested or working within the area of hair health. This includes nutritionists and dieticians, scientific beauticians, health workers and practitioners, college and university lecturers and undergraduate and graduate students.

Book Doping  Performance Enhancing Drugs  and Hormones in Sport

Download or read book Doping Performance Enhancing Drugs and Hormones in Sport written by Anthony C. Hackney and published by Elsevier. This book was released on 2017-11-23 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doping, Performance-Enhancing Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancing drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points. Presents the scientific concepts of how performance enhancers work, how they are used, and how they are detected and masked from detection Features language that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience Provides a short “close-up in each chapter to illustrate key topics that engage, entertain, and create a novel synthesis of thought

Book The Endocrine System in Sports and Exercise

Download or read book The Endocrine System in Sports and Exercise written by William J. Kraemer and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.

Book Concepts and Principles of Pharmacology

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Book Tietz Clinical Guide to Laboratory Tests   E Book

Download or read book Tietz Clinical Guide to Laboratory Tests E Book written by Alan H. B. Wu and published by Elsevier Health Sciences. This book was released on 2006-06-08 with total page 1856 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Norbert Tietz's classic handbook presents information on common tests as well as rare and highly specialized tests and procedures - including a summary of the utility and merit of each test. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. New and updated content has been added in all areas, with over 100 new tests added. Tests are divided into 8 main sections and arranged alphabetically. Each test includes necessary information such as test name (or disorder) and method, specimens and special requirements, reference ranges, chemical interferences and in vivo effects, kinetic values, diagnostic information, factors influencing drug disposition, and clinical comments and remarks. The most current and relevant tests are included; outdated tests have been eliminated. Test index (with extensive cross references) and disease index provide the reader with an easy way to find necessary information Four new sections in key areas (Preanalytical, Flow Cytometry, Pharmacogenomics, and Allergy) make this edition current and useful. New editor Alan Wu, who specializes in Clinical Chemistry and Toxicology, brings a wealth of experience and expertise to this edition. The Molecular Diagnostics section has been greatly expanded due to the increased prevalence of new molecular techniques being used in laboratories. References are now found after each test, rather than at the end of each section, for easier access.

Book Medicinal Plants of Central Asia  Uzbekistan and Kyrgyzstan

Download or read book Medicinal Plants of Central Asia Uzbekistan and Kyrgyzstan written by Sasha W. Eisenman and published by Springer Science & Business Media. This book was released on 2012-09-14 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is a collaborative effort between researchers at Rutgers University and colleagues from numerous institutions in Uzbekistan and Kyrgyzstan. It will be the first book to document more than 200 of the most important medicinal plants of Central Asia, many whose medicinal uses and activities are being described in English for the first time. The majority of the plants described grow wild in Central Asia with some being endemic, while other species have been introduced to Central Asia but are commonly used in regional plant based medicine. The book contains four introductory chapters. The first and second chapters cover the geography, climate and vegetation of Kyrgyzstan and Uzbekistan, respectively. The third chapter provides a brief history of medicinal plant use and science in Central Asia and the fourth chapter contains general information about phytochemistry. The fifth chapter comprises the bulk of the book and covers 208 medicinal plant species. Nearly all species have one or more high quality, color photographs. Three useful appendices have been included. The first is a glossary of botanical and ecological terms, the second is a glossary of chemistry terms and the third is a glossary of medical terms. During the preparation of this manuscript we found there to be a deficiency in quality reference resources for the translation of many of the technical terms associated with the different branches of science covered in this book. In order to make our job easier we compiled glossaries over the course of preparing the manuscript and have included them feeling that they will be an extremely valuable resource for readers. ​

Book Liver Disease in Children

    Book Details:
  • Author : Frederick J. Suchy
  • Publisher : Cambridge University Press
  • Release : 2021-03-18
  • ISBN : 1108911374
  • Pages : 875 pages

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2021-03-18 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

Book HDBK OF HORMONES VITAMINS   RADIOPAQUES

Download or read book HDBK OF HORMONES VITAMINS RADIOPAQUES written by Matthew Verderame and published by Springer. This book was released on 1986-08-31 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Laboratory Techniques in Thrombosis     a Manual

Download or read book Laboratory Techniques in Thrombosis a Manual written by J. Jespersen and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. It was the result of a unique cooperation between experts brought together by the European Concerted Action on Thrombosis and Disabilities (ECAT). The Concerted Action was at that time under the auspices of the Commission of the European Union. The second edition, like the first edition, deals with diagnostic tests within the field of thrombosis. However, the second edition has a broader scope because it is no longer limited by the frontiers of ECAT. Experts allover the world, in and outside ECAT, have contributed to this edition. The editors are very grateful for their contributions. The need for a new edition is obvious. Since 1992 new assays have been introduced for research, diagnosis, and therapy of thrombosis; for other assays improvements have been suggested, while a few others became redundant. The editors waived the radioimmunoassays of ~-thrombog1obulin and platelet factor 4 due to the fact that the kits required for these assays are rarely, or no longer, available. Also the PAI-1 activity assay was waived as it is liable to many inconsistencies and to large variations. A list of names and addresses of manufacturers marketing the kits and reagents has been compiled, together with a list of the recommended nomenclature of quantities in thrombosis and haemostasis, in order to facilitate the use of the updated version. These lists have been carefully compiled by Johannes J. Sidelmann, PhD, Department of Clinical Biochemistry in Esbjerg, Denmark.

Book Veterinary Herbal Medicine

    Book Details:
  • Author : Susan G. Wynn
  • Publisher : Elsevier Health Sciences
  • Release : 2006-11-29
  • ISBN : 0323029981
  • Pages : 736 pages

Download or read book Veterinary Herbal Medicine written by Susan G. Wynn and published by Elsevier Health Sciences. This book was released on 2006-11-29 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This full-color reference offers practical, evidence-based guidance on using more than 120 medicinal plants, including how to formulate herbal remedies to treat common disease conditions. A body-systems based review explores herbal medicine in context, offering information on toxicology, drug interactions, quality control, and other key topics. More than 120 herbal monographs provide quick access to information on the historical use of the herb in humans and animals, supporting studies, and dosing information. Includes special dosing, pharmacokinetics, and regulatory considerations when using herbs for horses and farm animals. Expanded pharmacology and toxicology chapters provide thorough information on the chemical basis of herbal medicine. Explores the evolutionary relationship between plants and mammals, which is the basis for understanding the unique physiologic effects of herbs. Includes a body systems review of herbal remedies for common disease conditions in both large and small animals. Discusses special considerations for the scientific research of herbs, including complex and individualized interventions that may require special design and nontraditional outcome goals.

Book Index to Theses Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards

Download or read book Index to Theses Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 1972 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: