Download or read book Functioning of Transmembrane Receptors in Signaling Mechanisms written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2011-04-05 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation. - Articles written and edited by experts in the field - Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events - Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field

Download or read book Endogenous Toxins 2 Volume Set written by Peter J. O'Brien and published by John Wiley & Sons. This book was released on 2009-12-02 with total page 1043 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as a first-stop reference for researchers and professionals in toxicology, pharmacology and medicine, this handbook is the very first to tie together the knowledge from many disciplines that has so far been available only from widely dispersed sources in the primary literature. As such, it presents the complete picture on what is currently known about endogenous toxins, including their generation, mode of action, resulting disease condition, and available countermeasures. Clearly divided into four parts, the first systematically covers important toxic molecule species, including metabolic intermediates and reactive oxygen species. The second discusses the role of genetically determined metabolic malfunctions, such as galactosemia, hyperlipidemia, porphyria, hemochromatosis and related conditions, while part three looks at acquired and chronic diseases caused or exacerbated by endogenous toxins, such as hepatic injury, asthma, rheumatism, colorectal cancer, reperfusion diseases, neurodegneration and aging. The final part reviews currents strategies to control and minimize the effect of endogenous toxins, either by nutritional or pharmacological interventions. With its complete coverage integrating molecular and systemic aspects from the biochemical basis to human disease conditions, this comprehensive reference will appeal to a broad target group of toxicologists, biochemists, nutrition specialists and physicians.

Download or read book Molecular Cellular and Tissue Engineering of the Vascular System written by Bingmei M. Fu and published by Springer. This book was released on 2018-10-12 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer’s disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.

Download or read book Nonverbal Communication written by Judith A. Hall and published by Walter de Gruyter. This book was released on 2013-01-30 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current volume, featuring 28 contributions from cutting-edge researchers, emphasizes uses, purposes, origins, and consequences of nonverbal communication in the lives of individuals, dyads, and groups - in other words, the behaviour of human beings. As such, the volume as a whole is not just about communication systems per se nor the impact on humans of the physical environment, whether built or natural. Instead, the volume focuses on humans engaging in nonverbal communication and the communicative and psychological aspects of this behaviour. Nonverbal behaviour is an inclusive category and includes all emitted nonverbal behaviour that may be subject to interpretation by others, whether the behaviour is intentionally produced or not. This panoramic volume, edited by two of the world's leading authorities on nonverbal communication, contains 28 essays presenting the state of the art in the domain of nonverbal behaviour study. Reginald B. Adams, Jr. Tamara D. Afifi Peter Andersen Sarai Blincoe Ross W. Buck Peter Bull Judee K. Burgoon Vanessa L. Castro Gaëtan Cousin Amanda Denes M. Robin DiMatteo John P. Doody John F. Dovidio Marshall Duke Hilary Anger Elfenbein José-Miguel Fernández-Dols Mark G. Frank Jillian Gannon Robert Gifford Laura K. Guerrero Sarah D. Gunnery Amy G. Halberstadt Judith A. Hall Jinni A. Harrigan Monica J. Harris Hyisung C. Hwang Jessica Kalchik Arvid Kappas Mark L. Knapp Eva Krumhuber Ravi S. Kudesia Dennis Küster Marianne LaFrance Jessica L. Lakin Leslie Martin David Matsumoto Joann M. Montepare Anthony J. Nelson Stephen Nowicki Alison E. Parker Sona Patel Miles L. Patterson Stacie R. Powers Kevin Purring Klaus Scherer Marianne Schmid Mast Michael A. Strom Elena Svetieva Joseph B. Walther Benjamin Wiedmaier Leslie A. Zebrowitz

Download or read book The Oxford Handbook of Language Prosody written by Carlos Gussenhoven and published by Oxford University Press, USA. This book was released on 2021-01-07 with total page 957 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook presents detailed accounts of current research in all aspects of language prosody, written by leading experts from different disciplines. The volume's comprehensive coverage and multidisciplinary approach will make it an invaluable resource for all researchers, students, and practitioners interested in prosody.

Download or read book Handbook of Amygdala Structure and Function written by Janice H. Urban and published by Academic Press. This book was released on 2020-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Amygdala Structure and Function, Volume 26, provides an updated overview on the functional neuroanatomy of amygdala nuclei, with an emphasis on interconnections (basolateral, central amygdala, medial amygdala) and their integration into related networks/circuits (prefrontal cortex, bed nucleus, nucleus accumbens). The design of this volume builds upon the foundations of functional neural circuits and the corresponding (cellular) electrophysiology important for the homeostatic control of amygdala function. This volume contains a dedicated section on the anatomical organization of the amygdala nuclei, emphasizing the role of neurotransmitters and neuropeptides that integrate signals and regulate behavior. Additional chapters discuss cellular physiology, plasticity and the integration of electrical signals that contribute to neural activity. The final section of the book connects the role of amygdala dysfunction and the development of disorders in human health and disease. - Emphasizes a comparative and multidisciplinary approach on the topic of the amygdala - Discusses, in detail, the role of amygdala dysfunction and the development of disorders in human health and disease - Examines the current state of research in cellular physiology, plasticity and the integration of electrical signals - Includes a dedicated section on neuropeptides, neurotransmitters and cannabinoids that links to behavior control

Download or read book Kv7 Channels Structure Physiology and Pharmacology written by Thomas Andrew Jepps and published by Frontiers Media SA. This book was released on 2021-07-02 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic was in partnership with CAP Partner for the International Kv7 Channels Symposium held in Naples, Italy on September 2019.

Download or read book Proceedings of the Eastern States Conference on Linguistics written by Eastern States Conference on Linguistics and published by . This book was released on 1995 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Seldin and Giebisch s The Kidney written by Robert J. Alpern and published by Academic Press. This book was released on 2012-12-31 with total page 3299 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic nephrology reference for over 25years, Seldin and Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch's The Kidney is your number one source for information. - Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters - Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation - Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions

Download or read book The effect of hearing loss on neural processing written by Jonathan E. Peelle and published by Frontiers Media SA. This book was released on 2015-06-03 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Efficient auditory processing requires the rapid integration of transient sensory inputs. This is exemplified in human speech perception, in which long stretches of a complex acoustic signal are typically processed accurately and essentially in real-time. Spoken language thus presents listeners’ auditory systems with a considerable challenge even when acoustic input is clear. However, auditory processing ability is frequently compromised due to congenital or acquired hearing loss, or altered through background noise or assistive devices such as cochlear implants. How does loss of sensory fidelity impact neural processing, efficiency, and health? How does this ultimately influence behavior? This Research Topic explores the neural consequences of hearing loss, including basic processing carried out in the auditory periphery, computations in subcortical nuclei and primary auditory cortex, and higher-level cognitive processes such as those involved in human speech perception. By pulling together data from a variety of disciplines and perspectives, we gain a more complete picture of the acute and chronic consequences of hearing loss for neural functioning.

Download or read book Perception and Cognition Interactions in the Aging Brain written by Harriet A. Allen and published by Frontiers Media SA. This book was released on 2016-09-13 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthy ageing can lead to declines in both perceptual and cognitive functions. Impaired perception, such as that resulting from hearing loss or reduced visual or tactile resolution, increases demands on ‘higher-level’ cognitive functions to cope or compensate. It is possible, for example, to use focused attention to overcome perceptual limitations. Unfortunately, cognitive functions also decline in old age. This can mean that perceptual impairments are exacerbated by cognitive decline, and vice versa, but also means that interventions aimed at one type of decline can lead to improvements in the other. Just as improved cognition can ameliorate perceptual deficits, improving the stimulus can help offset cognitive deficits. For example, making directions and routes easy to follow can help compensate for declines in navigation abilities. In this Topic, we bring together papers from both auditory and visual researchers that address the interaction between perception and cognition in the ageing brain. Many of the studies demonstrate that a broadening of representations or increased reliance on gist underlie perceptual and cognitive age-related declines. There is also clear evidence that impaired perception is associated with poor cognition although, encouragingly, it can also be seen that good perception is associated with better cognition. Compensatory cognitive strategies were less successful in improving perception than might be expected. We also present papers which highlight important methodological considerations that are required when studying the older brain.

Download or read book Role of TRPV4 Channels in Different Organ Systems written by and published by Academic Press. This book was released on 2022-10-07 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Role of TRPV4 Channels in Different Organ Systems, Volume 89, the latest release in the Current Topics in Membranes series, provides an in-depth description of the role of TRPV4 ion channels in different organ systems under healthy and disease conditions. Research over the last two decades shows crucial physiological and pathological roles for TRPV4 channels. In this volume, we present chapters focusing on TRPV4 channels in the vasculature, lungs, heart, kidney, bladder, skin, musculoskeletal system, eye, and immune cells. Understanding the behavior of TRPV4 channels in various organ systems will provide a big picture on their physiological roles and therapeutic targeting. - Provides a review of the role of TRPV4 channels in different organ systems - Presents a review of recent literature on TRPV4 channels - Includes easy to understand graphics, perspectives and future directions

Download or read book How Learning Works written by Susan A. Ambrose and published by John Wiley & Sons. This book was released on 2010-04-16 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for How Learning Works "How Learning Works is the perfect title for this excellent book. Drawing upon new research in psychology, education, and cognitive science, the authors have demystified a complex topic into clear explanations of seven powerful learning principles. Full of great ideas and practical suggestions, all based on solid research evidence, this book is essential reading for instructors at all levels who wish to improve their students' learning." —Barbara Gross Davis, assistant vice chancellor for educational development, University of California, Berkeley, and author, Tools for Teaching "This book is a must-read for every instructor, new or experienced. Although I have been teaching for almost thirty years, as I read this book I found myself resonating with many of its ideas, and I discovered new ways of thinking about teaching." —Eugenia T. Paulus, professor of chemistry, North Hennepin Community College, and 2008 U.S. Community Colleges Professor of the Year from The Carnegie Foundation for the Advancement of Teaching and the Council for Advancement and Support of Education "Thank you Carnegie Mellon for making accessible what has previously been inaccessible to those of us who are not learning scientists. Your focus on the essence of learning combined with concrete examples of the daily challenges of teaching and clear tactical strategies for faculty to consider is a welcome work. I will recommend this book to all my colleagues." —Catherine M. Casserly, senior partner, The Carnegie Foundation for the Advancement of Teaching "As you read about each of the seven basic learning principles in this book, you will find advice that is grounded in learning theory, based on research evidence, relevant to college teaching, and easy to understand. The authors have extensive knowledge and experience in applying the science of learning to college teaching, and they graciously share it with you in this organized and readable book." —From the Foreword by Richard E. Mayer, professor of psychology, University of California, Santa Barbara; coauthor, e-Learning and the Science of Instruction; and author, Multimedia Learning

Download or read book Alterations in the Sound Localization Pathway Related to Impaired Cocktail Party Performance written by Achim Klug and published by Frontiers Media SA. This book was released on 2022-05-09 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biology of Vascular Smooth Muscle written by Yuansheng Gao and published by Springer Nature. This book was released on 2022-12-08 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.

Download or read book The psychology of music in multimedia written by Siu-Lan Tan and published by OUP Oxford. This book was released on 2013-06-27 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: For most of the history of film-making, music has played an integral role serving many functions - such as conveying emotion, heightening tension, and influencing interpretation and inferences about events and characters. More recently, with the enormous growth of the gaming industry and the Internet, a new role for music has emerged. However, all of these applications of music depend on complex mental processes which are being identified through research on human participants in multimedia contexts. The Psychology of Music in Multimedia is the first book dedicated to this fascinating topic. The Psychology of Music in Multimedia presents a wide range of scientific research on the psychological processes involved in the integration of sound and image when engaging with film, television, video, interactive games, and computer interfaces. Collectively, the rich chapters in this edited volume represent a comprehensive treatment of the existing research on the multimedia experience, with the aim of disseminating the current knowledge base and inspiring future scholarship. The focus on empirical research and the strong psychological framework make this book an exceptional and distinctive contribution to the field. The international collection of contributors represents eight countries and a broad range of disciplines including psychology, musicology, neuroscience, media studies, film, and communications. Each chapter includes a comprehensive review of the topic and, where appropriate, identifies models that can be empirically tested. Part One presents contrasting theoretical approaches from cognitive psychology, philosophy, semiotics, communication, musicology, and neuroscience. Part Two reviews research on the structural aspects of music and multimedia, while Part Three focuses on research examining the influence of music on perceived meaning in the multimedia experience. Part Four explores empirical findings in a variety of real-world applications of music in multimedia including entertainment and educational media for children, video and computer games, television and online advertising, and auditory displays of information. Finally, the closing chapter in Part Five identifies emerging themes and points to the value of broadening the scope of research to encompass multisensory, multidisciplinary, and cross-cultural perspectives to advance our understanding of the role of music in multimedia. This is a valuable book for those in the fields of music psychology and musicology, as well as film and media studies.