Download or read book The Role of the Nuclear Matrix in the Organization and Control of DNA Replication in Eucaryotes written by Drew Mark Pardoll and published by . This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Structure and Gene Expression written by R. Curtis Bird and published by Elsevier. This book was released on 1996-11-28 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology.* Mechanisms of interaction between nuclear structure and genes* Gene expression regulation by elements of the nuclear matrix* How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Download or read book Nuclear Matrix written by Ronald Berezney and published by Elsevier. This book was released on 1995 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the nuclear matrix has grown enormously since Bereney and Coffey first reported its isolation and initial characterization in 1974. Since then, more than 1000 papers have been published on the subject by numerous workers around the world. This is the first book devoted to reviewing the major developments in this growing field. Key Features * The chapters cover a variety of topics, including: * Isolation of the nuclear matrix * Nuclear structure morphology in situ * Structural domains of the nuclear matrix and its components * Biochemistry and molecular biology of the matrix proteins and associated DNA and RNA * Functional properties associated with the nuclear matrix * DNA replication * Transcription * RNA splicing * Transcription regulation * Intranuclear and nucleocytoplasmic transport and targeting * Cell cycle regulation
Download or read book The Nuclear matrix and its role in the organization of the DNA during the nuclear cycle written by Ronny Jacobus Gerardus Opstelten and published by . This book was released on 1987 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Nuclear Envelope written by Sue Shackleton and published by Humana. This book was released on 2016-05-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a wide range of protocols used in studying the nuclear envelope, with special attention to the experimental adjustments that may be required to successfully investigate this complex organelle in cells from various organisms. The Nuclear Envelope: Methods and Protocols is divided into five sections: Part I – Nuclear Envelope Isolation; Part II – Nuclear Envelope Protein Interactions, Localization, and Dynamics; Part III – Nuclear Envelope Interactions with the Cytoskeleton; Part IV – Nuclear Envelope-Chromatin Interactions; and Part V – Nucleo-Cytoplasmic Transport. Many of the modifications discussed in this book have only been circulated within laboratories that have conducted research in this field for many years. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1990 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Extrachromosomal Elements in Lower Eukaryotes written by Reed Wickner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Replication Recombination and Repair written by Fumio Hanaoka and published by Springer. This book was released on 2016-01-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.
Download or read book Post transcriptional Processing and the Endocrine System written by Shern L. Chew and published by Karger Medical and Scientific Publishers. This book was released on 1999-01-01 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not much research has been done on the regulation of post-transcriptional events, much more is known about transcription. This book illustrates how hormones may influence post-transcriptional nuclear events and that some post-transcriptional modification is a requirement for the expression and function of most higher eukaryotic genes. Topics such as the regulation of pre-mRNA splicing by hormonal signals and tissue-specific mechanisms, pre-mRNA processing during spermatogenesis, to the link between the cell cycle and splicing, the role of phosphorylation and dephosphorylation in the function of the basal splicing machinery, RNA editing, the neuroendocrine regulation of polyadenylation all contribute to make up this volume. If you are an endocrinologist searching for interesting and important answers unearthed by RNA experiments, this book provides them.
Download or read book Biomedical Index to PHS supported Research pt A Subject access A H written by and published by . This book was released on 1992 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Control of Animal Cell Proliferation written by Alton L. Boynton and published by Elsevier. This book was released on 2013-09-24 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control of Animal Cell Proliferation, Volume I presents how animals regulate their proliferation activity and how cells become proliferatively autonomous resulting in malignant behavior. This book provides an understanding of mechanisms that control animal cell proliferation. Organized into five parts encompassing 17 chapters, this volume begins with an overview of the efforts to elucidate he genetic alterations that lead normal cells to become cancer cells, which have been aided considerably by the investigation of acute retroviruses. This text then examines the factors involved in growth control. Other chapters describe in detail the biology and biochemistry of epidermal growth factor (EGF), which have been elucidated through the study of cultured human fibroblasts. This book discusses as well the protein kinases with specificity for tyrosine. The final chapter deals with regulation of initiation of eukaryotic protein synthesis by phosphorylation. This book is a valuable resource for scientists as well as cellular and molecular biologists.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proteomics of Spermatogenesis written by G. S. Gupta and published by Springer Science & Business Media. This book was released on 2006-07-02 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments of experimental techniques in cellular and molecular biology have made it possible to understand the molecular biology of male gametogenesis in greater detail. This book focuses on the description of specialized proteins, which are dominantly and/or specifically expressed in germ cells and localized in spermatozoa. There is an urgent need to classify proteins of spermatogenic cells with a view of their functions, and their applications in the regulation of fertility and in understanding infertility. The understanding of structural properties of male germ cell specific proteins can offer vulnerable points for targeted intervention in testis without generalized effects on stages of spermatogenesis. Besides targeted action in male germ cells, sperm specific proteins and polypeptides may also offer potential application in the development of a contraceptive vaccine.
Download or read book Progress in Nonhistone Protein Research written by I. Bekhor Isaac and published by CRC Press. This book was released on 2018-05-04 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this text is to encourage research on nonhistones and to stimulate the imagination of other investigators whose future efforts might result in new discoveries as to the significance of these proteins.
Download or read book Essential Genetics written by Daniel Hartl and published by Jones & Bartlett Learning. This book was released on 2011 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to reflect the latest discoveries in the field, the Fifth Edition of Hartl's classic text provides an accessible, student-friendly introduction to contemporary genetics. Designed for the shorter, less comprehensive introductory course, Essential Genetics: A Genomic Perspective, Fifth Edition includes carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. New and updated sections on genetic analysis, molecular genetics, probability in genetics, and pathogenicity islands ensure that students are kept up-to-date on current key topics. The text also provides students with a sense of the social and historical context in which genetics has developed. The updated companion web site provides numerous study tools, such as animated flashcards, crosswords, practice quizzes and more! New and expanded end-of-chapter material allows for a mastery of key genetics concepts and is ideal for homework assignments and in-class discussion.
