Download or read book The Role of Immediate Early Genes in Neuropsychiatric Illness written by Amelia L. Gallitano and published by Frontiers Media SA. This book was released on 2020-03-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immediate Early Genes in Sensory Processing Cognitive Performance and Neurological Disorders written by Raphael Pinaud and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.
Download or read book Epigenetics in Psychiatry written by Jacob Peedicayil and published by Academic Press. This book was released on 2021-08-21 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field
Download or read book Cognitive deficits in schizophrenia and other neuropsychiatric disorders Convergence of preclinical and clinical evidence written by Ales Stuchlik and published by Frontiers Media SA. This book was released on 2015-10-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., abstract thinking, decision-making, attention, and several types of memory. Such deficits significantly disrupt quality of life and daily functioning of patients. Cognitive deficits in neuropsychiatric diseases are associated with alterations of brain morphology and function, and are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, i.e. measurable phenotypes linking these disaeses with discrete heritable and reproducible traits. This points to the importance of elucidating these endophenotypes in translational studies. Animal models may not mimic the full spectrum of clinical symptoms, but may act as analogies of particular behaviors or other pathological outcomes. They are useful to search for the etiology of particular psychiatric illnesses and novel therapeutics. Moreover, several behavioral tests to measure cognitive performance in rodents and other species have been implemented. The primary focus of the present topic is to provide up-to-date information on cognitive deficits of neuropsychiatric disorders, such as schizophrenia. This Research Topic also delineates future directions for translational studies aimed at developing novel treatments/interventions of cognitive disturbances.
Download or read book Transcranial Direct Current Stimulation in Neuropsychiatric Disorders written by André R. Brunoni and published by Springer Nature. This book was released on 2021-09-20 with total page 779 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges. tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of Medicine and JAMA Psychiatry. This 2nd edition summarizes the state of the art of the field. Written by leading experts in the field, the book is divided into 5 parts: Introduction and Mechanisms of Action; Research Methods; tDCS in the life cycle; Applications of tDCS in neuropsychiatric disorders (further divided into Psychiatry and Neurology); and The clinical use of tDCS. It also includes several new chapters, covering topics such as precision stimulation of tDCS; combination of tDCS with different neuroimaging modalities; and use of tDCS in new clinical conditions. Moreover, all chapters have been rewritten and updated. This book will be of significant interest to psychiatrists, neurologists and neuroscientists new to the field as well as those with a background in tDCS who want to increase their understanding of particular psychiatric conditions.
Download or read book Neuropsychiatric Disorders and Epigenetics written by Jacob Peedicayil and published by Elsevier. This book was released on 2023-09-29 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy. By helping to define epigenetics as a key player in neuropsychiatric disorders, this volume empowers new research, clinical translation, and pharmacological advances, and highlights promising directions for ongoing investigation. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Features extensive use of diagrams, illustrations, tables, and graphical abstracts for each section to reinforce understanding Includes chapter contributions from leading global experts
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press. This book was released on 2011-05-20 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.
Download or read book Neuronal Networks in Brain Function CNS Disorders and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Download or read book Massachusetts General Hospital Comprehensive Clinical Psychiatry written by Theodore A. Stern and published by Elsevier Health Sciences. This book was released on 2024-03-06 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Massachusetts General Hospital is widely regarded as one of the world's premier psychiatric institutions. Massachusetts General Hospital Comprehensive Clinical Psychiatry, 3rd Edition, offers practical, informative, and hands-on advice from the staff of the esteemed MGH Department of Psychiatry, helping you put today’s best practices to work for your patients. This authoritative reference covers a wide variety of clinical syndromes and settings, aided by superb graphics throughout. In one convenient volume, you’ll have easy access to the answers you need to face and overcome any clinical challenge. Uses a reader-friendly and highly templated format with abundant boxed summaries, bulleted points, case histories, algorithms, references, and suggested readings. Contains new chapters on the Psychiatric Management of Patients with Cardiac, Renal, Pulmonary, and Gastrointestinal Disease; COVID-19 Infection; Burns, Trauma, and Intensive Care Unit Treatment; Care of LGBTQ Patients; and Mindfulness and Resilience. Covers key areas, such as Substance Use Disorders; Mood, Anxiety, and Psychotic Disorders; Emergency Psychiatry; Functional Neuroanatomy and the Neurologic Examination; Psychological and Neuropsychological Assessment; Military Psychiatry; Psychiatric Manifestations of Traumatic Brain Injury; Legal and Ethical Issues in Psychiatry; End of Life Care; and Approaches to Collaborative Care and Primary Care Psychiatry. Features key points for every chapter, updated DSM-5 criteria, and enhanced content on collaborative care and behavioral medicine, ensuring that your knowledge is thorough and up to date. Corresponds to the companion review volume, Massachusetts General Hospital Study Guide for Psychiatry Exams, 2nd Edition (ISBN: 978-0-443-11983-5). Any additional digital ancillary content may publish up to 6 weeks following the publication date.
Download or read book Molecular mechanisms of substance abuse and its neurotoxicity written by Jie Yan and published by Frontiers Media SA. This book was released on 2023-01-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychiatric Genetics written by Thomas G. Schulze and published by Oxford University Press. This book was released on 2018 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of take home points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning about the key concepts and recent advances in the exciting field of psychiatric genetics.
Download or read book Molecular mechanisms of neuropsychiatric diseases written by Nashat Abumaria and published by Frontiers Media SA. This book was released on 2023-01-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of Neuropeptides in Drug Addiction and Other Psychiatric Disorders written by Marsida Kallupi and published by Frontiers Media SA. This book was released on 2022-07-27 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Gene Expression in the Nervous System written by Anna Maria Giuffrida Stella and published by . This book was released on 1990-07-19 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers an up-to-date account of the latest research findings concerned with the regulatory mechanisms of gene expression in neuronal and glial cells under different conditions. The book explores the cellular and neurobiological aspects of important phenomena of the nervous system and its role in health, disease and injury. Contributions from prominent scientists in the field address a variety of specific topics concerned with gene expression in the nervous system--from growth, hormonal and trophic factors to neural tissue reactions in injury or aging.
Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1995 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease written by Roger N. Rosenberg and published by Academic Press. This book was released on 2020-06-24 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Provides comprehensive coverage on the neurogenetic foundation of neurological and psychiatric disease Presents detailed coverage of genomics, animal models and diagnostic methods, with new coverage on evaluating patients with biochemical abnormalities or gene mutations Includes new chapters on the pharmacogenomics of epilepsy and the most recent updates in molecular genetics, focusing on neurodegenerative and psychiatric diseases
