Download or read book The Quest for Cortisone written by Thom Rooke and published by MSU Press. This book was released on 2012-01-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound—cortisone—her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”
Download or read book Foundation written by Eric Goodman and published by Rodale Books. This book was released on 2011-05-10 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sense of fatigue dogs the fitness world. Many of the new programs that are tagged as groundbreaking are actually recycled ideas. Foundation offers something completely different for novices and athletes alike: a simple program with powerful and proven results that will remedy bad posture, alleviate back pain, and help readers break through fitness challenges and plateaus. Dr. Eric Goodman, a brilliant and dynamic young chiropractor, teams up with Peter Park, one of the top trainers in the United States, to radically redefine the core--shifting the focus from the front of the body to the back. Their groundbreaking approach works to strengthen the lower back and the full posterior chain and correct poor movement patterns by addressing mechanical imbalances and weaknesses. Foundation training involves simple movement patterns and is equipment free, creating maximum power, flexibility, and endurance. Word-of-mouth enthusiasm has inspired both Hollywood luminaries and world-class athletes to make Foundation training the core of their fitness programs. Eric and Peter's client list has grown exponentially to include Lance Armstrong, NBA star Derek Fisher, world-champion surfer Kelly Slater, and actor Matthew McConaughey.
Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
Download or read book Atomic Bill written by Vincent Kiernan and published by Cornell University Press. This book was released on 2022-11-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Atomic Bill, Vincent Kiernan examines the fraught career of New York Times science journalist, William L. Laurence and shows his professional and personal lives to be a cautionary tale of dangerous proximity to power. Laurence was fascinated with atomic science and its militarization. When the Manhattan Project drew near to perfecting the atomic bomb, he was recruited to write much of the government's press materials that were distributed on the day that Hiroshima was obliterated. That instantly crowned Laurence as one of the leading journalistic experts on the atomic bomb. As the Cold War dawned, some assessed Laurence as a propagandist defending the militarization of atomic energy. For others, he was a skilled science communicator who provided the public with a deep understanding of the atomic bomb. Laurence leveraged his perch at the Times to engage in paid speechmaking, book writing, filmmaking, and radio broadcasting. His work for the Times declined in quality even as his relationships with people in power grew closer and more lucrative. Atomic Bill reveals extraordinary ethical lapses by Laurence such as a cheating scandal at Harvard University and plagiarizing from press releases about atomic bomb tests in the Pacific. In 1963 a conflict of interest related to the 1964 World's Fair in New York City led to his forced retirement from the Times. Kiernan shows Laurence to have set the trend, common among today's journalists of science and technology, to prioritize gee-whiz coverage of discoveries. That approach, in which Laurence served the interests of governmental official and scientists, recommends a full revision of our understanding of the dawn of the atomic era.
Download or read book The Antidote written by Barry Werth and published by Simon and Schuster. This book was released on 2014-02-04 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.
Download or read book Corticosteroids An Issue of Rheumatic Disease Clinics of North America written by Marcy B. Bolster and published by Elsevier Health Sciences. This book was released on 2016-01-19 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Corticosteroids represent the most important and frequently used class of anti-inflammatory and immunosuppressant agents in the management of many rheumatological conditions. Included in this issue will be articles on the following topics: Glucocorticoid use in intra-articular and soft tissue injections, corticosteroids and osteoporosis, corticosteroids in lupus, ANCA associated vasculitis, and many more!
Download or read book Dmso written by Morton Walker D.P.M. and published by Penguin. This book was released on 1993-01-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: An easy-to-understand, up-to-date guide on the highly publicized drug, DMSO DMSO—dimethyl sulfoxide—is a simple by-product of wood and has been called a “miracle” drug, capable of relieving pain, diminishing swelling, reducing inflammation, encouraging healing, and restoring normal function. In this groundbreaking work, award-winning health science writer Dr. Morton Walker examines the powerful and compelling case for the use of DMSO in the treatment of many debilitating disease and health-related problems. In DMSO: Nature’s Healer, Dr. Walker cites documented cases of its astounding use in healing and prevention of a host of health disorders, including arthritis, stroke, cancer, mental retardation, and sports and auto injuries. He also recounts the dramatic story of the long struggle to gain FDA approval of DMSO.
Download or read book General and Comparative Endocrinology written by A.M. Schreiber and published by CRC Press. This book was released on 2023-11-24 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: General and Comparative Endocrinology: An Integrative Approach, takes a holistic approach to endocrinology, introducing students to the diverse facets of this interdisciplinary science ranging from the medical to comparative domains, while also exploring evolutionary, environmental, and conservation specializations within the field. The textbook is founded on the principle that students interested in the health sciences will benefit from understanding how proficiency in endocrine function among a diversity of organisms contributes to advances in modern medicine. Likewise, students intrigued by comparative physiology will benefit from the wealth of knowledge derived from medical/clinical endocrinology, the historical bedrock of the field. This textbook represents the modern field of endocrinology in its totality by addressing topics and recent advances not currently discussed in other introductory endocrinology textbooks. Key Features Introduces the broad and interdisciplinary scope of endocrinology. Provides clear chapter objectives and key concepts. Includes summary and synthesis questions for each chapter that are suitable for exams and quizzes. Includes a chapter devoted to endocrine-disrupting chemicals. Describes the roles played by the endocrine system in important health challenges related to appetite regulation, obesity, diabetes, and other diseases stemming from ‘mismatches to modernity’. Integrates evolutionary and comparative approaches to hormones and health.
Download or read book Steroid Analysis written by Hugh L. J. Makin and published by Springer Science & Business Media. This book was released on 2010-06-04 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this handbook concentrates on the analysis of steroids in biological fluids. It offers analysis of low levels of steroid analytes in biological fluids. This new edition also provides an extra chapter on pharmaceutical aspects of steroid analysis. Coverage details spectroscopic and other methods, including UV and IR absorption spectroscopy, NMR spectroscopy, mass spectrometry, X-ray diffraction, chromatography and immunoassay of steroids.
Download or read book Laboratory Guide to the Methods in Biochemical Genetics written by Nenad Blau and published by Springer Science & Business Media. This book was released on 2008-05-31 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.
Download or read book The Beautiful Cure written by Daniel M. Davis and published by University of Chicago Press. This book was released on 2021-03-19 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Visceral.”—Wall Street Journal “Illuminating.”—Publishers Weekly “Heroic.”—Science The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy.
Download or read book The Hypothalamus Pituitary Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.
Download or read book Cinema MD written by Eelco F.M. Wijdicks MD, PhD and published by Oxford University Press. This book was released on 2020-02-28 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cinema, MD follows the intersection of medicine and film and how filmmakers wrote a history of medicine over time. The narrative follows several main story lines: How did the portrayal of physicians, nurses, and medical institutions change over the years? What interested filmmakers, and which topics had priority? What does film's obsession with experiments and monstrosities reveal about medical ethics and malpractice? How could the public's perception of the medical profession change when watching these films on diseases and treatments, including palliative care and medical ethics? Are screenwriters, actors, and film directors channeling a popular view of medicine? Cinema, MD analyzes not only changing practices, changing morals, and changing expectations but also medical stereotypes, medical activism, and violations of patients' integrity and autonomy. Examining over 400 films with medical themes over a century of cinema, this book establishes the cultural, medical, and historical importance of the art form. Film allows us to see our humanity, our frailty, and our dependence when illness strikes. Cinema, MD provides uniquely new and fascinating insight into both film criticism and the history of medicine and has a resonance to the medical world we live in today.
Download or read book Steroid Hormone Receptors in Health and Disease written by Raj Kumar and published by Elsevier. This book was released on 2023-12-15 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases. Discusses the importance of steroid hormone receptors in the physiology and pathophysiology of various endocrine related diseases Provides state-of-the-art information based on key research findings in the field, along with hypotheses and perspectives for future directions for basic and translational research and clinical applications Offers a comprehensive description of the challenges associated with steroid hormone receptors-based therapies
Download or read book Crooked written by Cathryn Jakobson Ramin and published by HarperCollins. This book was released on 2017-05-09 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acclaimed author of Carved in Sand—a veteran investigative journalist who endured persistent back pain for decades—delivers the definitive book on the subject: an essential examination of all facets of the back pain industry, exploring what works, what doesn't, what may cause harm, and how to get on the road to recovery. In her effort to manage her chronic back pain, investigative reporter Cathryn Jakobson Ramin spent years and a small fortune on a panoply of treatments. But her discomfort only intensified, leaving her feeling frustrated and perplexed. As she searched for better solutions, she exposed a much bigger problem. Costing roughly $100 billion a year, spine medicine—often ineffective and sometimes harmful —exemplified the worst aspects of the U.S. health care system. The result of six years of intensive investigation, Crooked offers a startling look at the poorly identified risks of spine medicine, and provides practical advice and solutions. Ramin interviewed scores of spine surgeons, pain management doctors, physical medicine and rehabilitation physicians, exercise physiologists, physical therapists, chiropractors, specialized bodywork practitioners. She met with many patients whose pain and desperation led them to make life-altering decisions, and with others who triumphed over their limitations. The result is a brilliant and comprehensive book that is not only important but essential to millions of back pain sufferers, and all types of health care professionals. Ramin shatters assumptions about surgery, chiropractic methods, physical therapy, spinal injections and painkillers, and addresses evidence-based rehabilitation options—showing, in detail, how to avoid therapeutic dead ends, while saving money, time, and considerable anguish. With Crooked, she reveals what it takes to outwit the back pain industry and get on the road to recovery.
Download or read book At Zero written by Joe Vitale and published by John Wiley & Sons. This book was released on 2013-10-31 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: New stories and new processes that outline the fourth stage of awakening of ho'oponopono Author Joe Vitale's previous book, Zero Limits, presented a unique self-help breakthrough focused on helping overworked, overstressed individuals overcome obstacles and achieve their goals. It was the first book to explain how a secret Hawaiian method called ho'oponopono can help people experience health, wealth, happiness, and more. It empowered thousands of readers to take control of everything in their lives in order to achieve all they’ve ever dreamed of. At Zero starts where Zero Limits left off. It offers new stories, explains new process, and reveals the fourth stage of awakening. Explains the process called "cleaning," to delete programs and beliefs that you aren't aware of Shows how repeating the phrases I love you, I'm sorry, Please forgive me, Thank you can help you reach Divinity Life will always present you with challenges. The practice of ho'oponopono, as revealed by author Joe Vitale, guides you through the journey of life with the tools you need to rid yourself of hindrances and open yourself up to infinite possibilities.
Download or read book The Feminine Mystique written by Betty Friedan and published by W. W. Norton & Company. This book was released on 2001-09-17 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book that changed the consciousness of a country—and the world. Landmark, groundbreaking, classic—these adjectives barely describe the earthshaking and long-lasting effects of Betty Friedan's The Feminine Mystique. This is the book that defined "the problem that has no name," that launched the Second Wave of the feminist movement, and has been awakening women and men with its insights into social relations, which still remain fresh, ever since. A national bestseller, with over 1 million copies sold.
