Download or read book The Projections to the Spinal Cord of the Rat During Development written by Egbert Lakke and published by . This book was released on 1997-06-19 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Projections to the Spinal Cord of the Rat During Development A Timetable of Descent written by Egbert Lakke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The studies described here were carried out in the Neuroregulation Group at the Department of Physiology of the University of Leiden. Over the last decade this group has, in close collaboration with the departments of neurosurgery and urology of the Academic Hospital of Leiden, studied development and regeneration of the spinal cord and its peripheral nerves both from a neuroanatomical and a clinical perspective. During this period the development of brainstem projections to the spinal cord of the rat was studied with a retrograde tracing technique. Horseradish peroxidase was injected into the spinal cord of rat fetuses, both at different ages, and at different levels of the spinal cord. These studies aimed to discover regularities in the behavior of descending fiber systems that could yield insight into the logic that the nervous system must employ to structure its connectional pattern during development. Such insight might then be applied to improve regeneration of the nervous system.
Download or read book Development of the Human Spinal Cord written by Joseph Altman and published by Oxford University Press, USA. This book was released on 2001 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: There exists a wealth of information about the development of the spinal cord in journal articles and monographs, yet this beautifully illustrated work is the first book devoted to this important topic. Because the developing human spinal cord cannot be subjected to experimental manipulations, the knowledge gained from experimental work in animals is applied here to an interpretation of the time course and mechanisms of spinal cord development in man. The book begins with a review of our current understanding of the structure and functions of the spinal cord. Special reference is made to the phylogeny of the vertebrate spinal cord because the authors' interpretation of the development and organization of the human spinal cord is specifically an evolutionary one. Following a detailed experiment-based account of spinal cord development in the rat, the development of the human spinal cord is described, illustrated and interpreted in separate chapters during three epochs: the first trimester (the embryonic period), the second and third trimesters (the fetal period), and the first year of postnatal life. Special attention is paid to such topics as neurons, and the growth and myelination of the ascending and descending fiber tracts of the spinal cord. The book ends with a correlation of the development of motor behavior with different stages in the morphological development of the human spinal cord during the embryonic, fetal, and postnatal periods. The successive acquisition of voluntary control over different parts of the body during infancy is correlated with the progressive myelination of the corticospinal tract. * The book contains an extensive review of work on spinal cord organization and development throughout the 20th century. * The interpretations are based on experimental studies of spinal cord development in the rat carried out by the authors and their associates. * The histological material on human spinal cord development is the largest ever assembled and reproduced (combining the Carnegie, Minot, and Yakovlev Collections). * The collected material (which varies in quality and some of it has begun to fade) has been digitized and electronically reprocessed for improved reproduction. * Discrete components of the spinal cord and new developments are highlighted by color coding; typically on one side only, leaving the contralateral side untouched to allow the reader to use his own interpretation. * Summary graphs are presented, many in color, to convey important structural relationships, developmental events, or theories. * The authors revive a few forgotten theories and offer several new ones regarding the development and organization of the human spinal cord. Development of the Human Spinal Cord will be of interest to developmental biologists, neuroscientists, embryologists, molecular biologists (those working on stem cell research), pediatric neurologists, pathologists, child and developmental psychologists, and their students and trainees
Download or read book Neuraxial Therapeutics written by Tony Yaksh and published by Springer Nature. This book was released on 2024-01-02 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Motor Neurobiology of the Spinal Cord written by Timothy C. Cope and published by CRC Press. This book was released on 2001-06-26 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor Neurobiology of the Spinal Cord provides a comprehensive description of the experimental tools available for investigating the neuronal properties that allow populations of spinal cord neurons to control muscles responsible for limb movements and posture control. By integrating data from many new approaches, this text demonstrates how spinal cord circuits operate under a variety conditions and explores the new and exciting developments that are being made in motor neurobiology of the spinal cord. It also elucidates concepts and principles relevant to function and structure throughout the nervous system and presents information about changes induced by injury and disease.
Download or read book Development of the Rat Spinal Cord Immuno and Enzyme Histochemical Approaches written by Martin F. Bach and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The studies described here were carried out in the Neuroregul ation Group, Department of Physiology, University of Leiden, the Netherlands. Over the last decade, this group, in close collaboration with the Department of Neurosurgery of the Academic Hospital of Leiden, has studied the development of the central nervous system from a neuroanatomical as well as a clinical perspective. During this period, the expression of several morphore gulators in the developing rat spinal cord was extensively investigated. Parallel studies focused on the development of the spinal cord fiber systems, which was studied by means of the intrauterine use of neuronal tracers. The main goal of these studies was to extend our knowledge about the (normal) generation of the spinal cord and to contribute to the under standing of clinical problems related to regeneration and degeneration in the mammalian central nervous system. The studies on morphoregulators, in particular, appeared to benefit two different scientific areas. Firstly, the correlation between morphoregulator expression patterns and known anatomy contributed to our knowledge about spinal cord development. Secondly, the correlation between morpho regulator expression patterns and known developmental processes may help to understand their precise function(s). This volume of Advances in Anatomy, Embryology and Cell Biology presents these particular studies on the development of the rat spinal cord performed over the last decade. As well as integrating the results of the tracer studies, this volume also provides an update on the development of the rat spinal cord.
Download or read book Handbook of Developmental Neurotoxicology written by William Slikker Jr. and published by Elsevier. This book was released on 1998-08-10 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. Written by internationally recognized experts on developmental neurotoxicology Includes extensive references Well illustrated with diagrams, charts and tables Provides coverage of basic neurobiology as well as neurotoxicology
Download or read book The Rat Nervous System written by George Paxinos and published by Gulf Professional Publishing. This book was released on 2004-05-05 with total page 1329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of the standard reference on the nervous system of the rat is a complete and updated revision of the 1994 second edition. All chapters have been extensively updated, and new chapters added covering early segmentation, growth factors, and glia. The book is now aligned with the data available in the Rat Brain in Stereotaxic Coordinates, making it an excellent companion to this bestselling atlas. Physiological data, functional concepts, and correlates to human anatomy and function round out the new edition. Designed to be used in conjunction with the bestselling Rat Brain in Stereotaxic Coordinates New to this edition is inclusion of physiological data, functional concepts, and correlates to human anatomy and function in each chapter Contains new chapters on early segmentation of the central nervous system, growth factors and glia
Download or read book The Projections to the Spinal Cord of the Rat During Development A Timetable of Descent written by Egbert Lakke and published by Springer. This book was released on 1997-06-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The studies described here were carried out in the Neuroregulation Group at the Department of Physiology of the University of Leiden. Over the last decade this group has, in close collaboration with the departments of neurosurgery and urology of the Academic Hospital of Leiden, studied development and regeneration of the spinal cord and its peripheral nerves both from a neuroanatomical and a clinical perspective. During this period the development of brainstem projections to the spinal cord of the rat was studied with a retrograde tracing technique. Horseradish peroxidase was injected into the spinal cord of rat fetuses, both at different ages, and at different levels of the spinal cord. These studies aimed to discover regularities in the behavior of descending fiber systems that could yield insight into the logic that the nervous system must employ to structure its connectional pattern during development. Such insight might then be applied to improve regeneration of the nervous system.
Download or read book Applied Biological Engineering written by Ganesh R. Naik and published by BoD – Books on Demand. This book was released on 2012-03-23 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological engineering is a field of engineering in which the emphasis is on life and life-sustaining systems. Biological engineering is an emerging discipline that encompasses engineering theory and practice connected to and derived from the science of biology. The most important trend in biological engineering is the dynamic range of scales at which biotechnology is now able to integrate with biological processes. An explosion in micro/nanoscale technology is allowing the manufacture of nanoparticles for drug delivery into cells, miniaturized implantable microsensors for medical diagnostics, and micro-engineered robots for on-board tissue repairs. This book aims to provide an updated overview of the recent developments in biological engineering from diverse aspects and various applications in clinical and experimental research.
Download or read book The Influence of Ethyl Alcohol on the Development of the Chondrocranium of Gallus Gallus written by Marise Heyns and published by Springer. This book was released on 1996-12-13 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a valuable contribution to the influence of a teratological agent on early avian development, especially the chondrocranium. Cranial abnormalities developing from the experimental application of ethyl alcohol on genetically and nutritionally uniform chick embryos are described in detail and compared to the normal stages of development. A full discussion and evaluation are provided regarding the gross abnormalities and malformations observed in microscopical and histological investigations. The value of avian material for the experimental applicaion of teratogenic material is demonstrated.
Download or read book Development of the Hypothalamus written by Gonzalo Alvarez-Bolado and published by Frontiers Media SA. This book was released on 2015-08-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamus is the region of the brain in charge of the maintenance of the internal milieu of the organism. It is also essential to orchestrate reproductive, parental, aggressive-defensive, and other social behaviors, and for the expression of emotions. Due to the structural complexity of the hypothalamus, however, many basic aspects of its ontogenesis are still mysterious. Nowadays we assist to a renewal of interest spurred in part by the growing realization that prenatal and early postnatal influences on the hypothalamus could entail pathological conditions later in life. Intriguing questions for the future include: do early specification phenomena reflect on adult hypothalamic function and possibly on some kinds of behavior? Can early events like specification, migration or formation of nuclei influence adult hypothalamic function? A change in morphological paradigm, from earlier columnar interpretations to neuromeric ones, is taking place. Concepts long taken for granted start to be challenged in view of advances in developmental and comparative neurobiology, and notably also in the molecular characterization of hypothalamic structures. How should we understand the position of the hypothalamus in relation to other brain regions? Should we bundle it together with the thalamus, a functionally, genetically and developmentally very different structure? Does the classic concept of “diencephalon” make sense, or should the hypothalamus be separated? Does the preoptic area belong to the hypothalamus or the telencephalon? The answer to these questions in the context of recent causal molecular analysis will help to understand hypothalamic evolution and morphogenesis as well as its adult function and connectivity. In this Research Topic we have reviewed the fundamentals of hypothalamic ontogenesis and evolution, summarizing present-day knowledge, taking stock of the latest advances, and anticipating future challenges.
Download or read book Hand and Brain written by and published by Elsevier. This book was released on 1996-06-24 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Used for gestures of communication, environmental exploration, and the grasping and manipulating of objects, the hand has a vital role in our lives. The hand's anatomical structure and neural control are among the most complex and detailed of human motor systems. Hand and Brain is a comprehensive overview of the hand's sensorimotor control. It discusses mediating variables in perception and prehension, the coordination of muscles with the central nervous system, the nature of movement control and hand positioning, hand-arm coordination in reaching and grasping, and the sensory function of the hand. In the last decade the rapid growth of neuroscience has been paralleled by a surge of interest in hand function. This reflects the fact that many of the fundamental issues facing neuroscientists today--including the problem of relating physiology to behavior--are central to the study of sensorimotor control of the hand. This book takes a broad interdisciplinary perspective on the control of hand movements that includes neurophysiology, neuroanatomy, psychology and neuropsychology, and biomechanics. The authors, who have all made significant scientific contributions in their own right, have sought to introduce their chosen topics in a manner that the undergraduate reader will be able to follow without sacrificing detailed and up-to-date coverage ofthe major developments. Uses an interdisciplinary approach including behavioral and neurophysiological data Describes a variety of experimental methodologies Treats neural computations necessary for the control of movement Covers implications of biomechanics for control, sensory mechanisms, and perceptual processing (haptics) Includes manipulative hand function as well as reaching Overviews each group of chapters using link sections Contains an integrated index and a glosssary The five sections cover: Mediating variables in perception and prehension The coordination of muscles with the central nervous system The nature of movement control and hand positioning Hand-arm coordination in reaching and grasping The sensory function of the hand
Download or read book Pain Modulation written by Howard L. Fields and published by Elsevier Publishing Company. This book was released on 1988-01-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.
Download or read book Oxytocin Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comparative overview of the effects of neuropeptides on behavior, examining parallel findings in both humans and non-human animals.
Download or read book Oxford Handbook of Developmental Behavioral Neuroscience written by Mark Blumberg and published by OUP USA. This book was released on 2010 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbook of Developmental Behavioral Neuroscience is a seminal reference work in the burgeoning field of developmental behavioral neuroscience, which has emerged in recent years as an important sister discipline to developmental psychobiology. This handbook, part of the Oxford Library of Neuroscience, provides an introduction to recent advances in research at the intersection of developmental science and behavioral neuroscience, while emphasizing the central research perspectives of developmental psychobiology. Contributors to the Oxford Handbook of Developmental Behavioral Neuroscience are drawn from a variety of fields, including developmental psychobiology, neuroscience, comparative psychology, and evolutionary biology, demonstrating the opportunities to advance our understanding of behavioral and neural development through enhanced interactions among parallel disciplines.In a field ripe for collaboration and integration, the Oxford Handbook of Developmental Behavioral Neuroscience provides an unprecedented overview of conceptual and methodological issues pertaining to comparative and developmental neuroscience that can serve as a roadmap for researchers and a textbook for educators. Its broad reach will spur new insights and compel new collaborations in this rapidly growing field.
