Download or read book The Perplexing Physiology of the Nociceptive System written by Istvan Nagy and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impacts that threaten or indeed compromise the integrity of tissues trigger the development of a defence response, which through the activity of the nociceptive system includes pain. If the noxious impact does not induce tissue damage, the pain, called “nociceptive” pain, ceases within seconds after the impact is withdrawn. In contrast, if tissue damage does occur, a pain experience that usually persists until the injury is resolved and includes two major pathological sensory experiences, hypersensitivity to heat stimuli (i.e. heat hyperalgesia) and/or hypersensitivity to mechanical stimuli (i.e. mechanical allodynia) develop. The cellular and molecular mechanisms underlying the development of nociceptive pain are fairly well understood. Our understanding of the development of pain associated with tissue injury has also significantly improved in the last decades. Hence, two fundamental mechanisms, interactions between the nervous and immune systems both within and without the central nervous system and sensitization that is a use-dependent increase in the sensitivity and activity of neurons involved in nociceptive processing have been identified being pivotal for the development of tissue injury-associated pain. However, important details of the cellular and molecular mechanisms, which account for the development of the pathological sensory experiences and those experiences becoming persistent, still await elucidation.
Download or read book The Essence of Analgesia and Analgesics written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2010-10-14 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.
Download or read book The Human Pain System written by Frederick A. Lenz and published by Cambridge University Press. This book was released on 2010-01-21 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is a subject of significant scientific and clinical interest. This has resulted both from realistic rodent models, and the publication of imaging, psychological and pharmacological studies in humans. Investigators studying rodents refer to anatomical and physiological studies in non-human primates to make their results relevant to humans. Psychophysical and pharmacological studies in humans are interpreted in terms of anatomical and physiological studies in animals; primarily evidence from rodents and cats. There are significant differences in pain mechanisms between these species and primates. Over 20 years of imaging studies have demonstrated the activation of human cortical and subcortical structures in response to painful stimuli. Interpretation of these results relies upon an understanding of the anatomy and physiology of these structures in primates. Jones, Lenz, Casey and Willis review the anatomy and physiology of nociception in monkeys and humans, and provide a firm basis for interpreting studies in humans.
Download or read book Chronic Pain and Brain Abnormalities written by Carl Y. Saab and published by Academic Press. This book was released on 2013-06-28 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics
Download or read book Pain written by Hubert van Griensven and published by Elsevier Health Sciences. This book was released on 2013-12-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly anticipated new edition of Pain: a textbook for health professionals (previous subtitle a textbook for therapists) has undergone a major rewrite in order to reflect the rapid developments in the field of pain management. It highlights an effective and evidence-based method, providing the theoretical basis to help with the assessment and management of persistent pain, while also discussing in depth a range of specific approaches. Pain: a textbook for health professionals is written emphatically from a biopsychosocial perspective. In order to set the scene, the introductory section includes chapters on the patient’s voice and social determinants of pain. This ensures that the deeply personal and social aspects of pain are not lost among the more technical and biological commentary. These aspects provide an overall context, and are revisited in chapters on participation of life roles, work rehabilitation and psychology. The basic science section includes key chapters on the psychology, neuroanatomy and neurophysiology of pain. This provides a basis for subsequent chapters on specific approaches such as pharmacology, physical therapy and complementary medicine. Pain in specific patient groups, including children, the elderly and those with cancer, are dealt with in separate chapters, as are pain problems such as complex regional pain syndrome and chronic spinal pain. Although the emphasis of the book is on long term pain, acute pain is discussed as a possible precursor and determinant of chronicity. Patient-centred approach to care – advocates listening to the patient’s voice Covers social determinants of pain Guides the reader from pain psychology to the practical application of psychological interventions Learning aids – chapter objectives, reflective exercises, case examples, and revision questions Emphasizes an evidence-based perspective Written by an international team of experts topics such as pain in children and the elderly, pain education for professionals, disability and medico-legal aspects expanded focus on complex regional pain syndrome, acupuncture and psychology improved layout for a better learning and studying experience
Download or read book Musculoskeletal Disorders and the Workplace written by Institute of Medicine and published by National Academies Press. This book was released on 2001-06-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.
Download or read book Wall Melzack s Textbook of Pain E Book written by Stephen B. McMahon and published by Elsevier Health Sciences. This book was released on 2013-03-01 with total page 1507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apply the latest scientific and clinical advances with Wall & Melzack's Textbook of Pain, 6th Edition. Drs. Stephen McMahon, Martin Koltzenburg, Irene Tracey, and Dennis C. Turk, along with more than 125 other leading authorities, present all of the latest knowledge about the genetics, neurophysiology, psychology, and assessment of every type of pain syndrome. They also provide practical guidance on the full range of today's pharmacologic, interventional, electrostimulative, physiotherapeutic, and psychological management options. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Benefit from the international, multidisciplinary knowledge and experience of a "who's who" of international authorities in pain medicine, neurology, neurosurgery, neuroscience, psychiatry, psychology, physical medicine and rehabilitation, palliative medicine, and other relevant fields. Translate scientific findings into clinical practice with updates on the genetics of pain, new pharmacologic and treatment information, and much more. Easily visualize important scientific concepts with a high-quality illustration program, now in full color throughout. Choose the safest and most effective management methods with expanded coverage of anesthetic techniques. Stay abreast of the latest global developments regarding opioid induced hyperalgesia, addiction and substance abuse, neuromodulation and pain management, identification of specific targets for molecular pain, and other hot topics.
Download or read book Neuronal Networks in Brain Function CNS Disorders and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Download or read book Temporomandibular Disorders written by César Fernández-de-las-Peñas and published by Jessica Kingsley Publishers. This book was released on 2018-05-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative and comprehensive account of the assessment and conservative management of temporomandibular disorders. Recent emphasis has been on 'evidence-based practice' at the expense of the clinical reality which should also take account of clinician expertise and patient preference. A sound research base is not always available. This text addresses the clinical reality of having to make decisions using other sources of knowledge in the absence of a comprehensive scientific rationale. It advocates clinical and evidence-informed practice - an approach which acknowledges the value of clinician experience and expertise as well as research findings. Compiled and edited by two highly regarded and experienced practitioners, researchers and authors who have already published many books and journal articles in the field. With contributions from a mix of 28 internationally-based clinicians and clinician-researchers allowing the text to highlight both current best evidence and clinicians' expertise and experience. Contributors include talented young clinicians as well as established experts in orthopaedic physiotherapy and world-level expert researchers.
Download or read book Neurological Pathophysiology written by Alan L. Pearlman and published by Oxford University Press, USA. This book was released on 1984 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the third edition, this highly praised textbook has been thoroughly revised to provide much greater detail on basic neuroscience, anatomic pathology, and the major diseases encountered in clinical neurology. "A superb balance between basic sciences and their clinical applications. ... Recommended with enthusiasm." --Journal of the American Medical Association, on the second edition With new editors, new authors for most sections, and a reorganized table of contents, the third edition of this widely used introduction to the scientific foundations of clincial neurology provides much greater detail on basic neuroscience and a more comprehensive discussion of the major diseases encountered by clinicians. The authors, all clinicians involved in laboratory and clinical investigations, have reviewed normal structure and function stressing the relationship between disordered physiology and the clinical manifestations of disease.
Download or read book Management of Patients with Chronic Pain written by Steven F. Brena and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written for the general health care professional, from every medical and paramedical specialization. Because pain is the most common factor driving patients to seek professional advice, it is likely that every physician, psychologist, and therapist has been clinically exposed to the difficulty and the frequent frustration of dealing with people in pain. All of them may find in this book some explanations for their puzzles and some updated information, which usually are published in specialized journals not ordinarily read by the general practitioner. Actually the book has been addressed to professionals at two different levels of general practice. At one level is the busy practitioner who treats most patients with' 'acute" pain, and who may use this information in daily practice to prevent the onset of chronic pain; a common effort from all professionals currently is needed to curb the "epidemic" of chronic pain in the United States. At another level the book has been addressed to the practitioner who may have a more intense desire to become involved in the actual management of chronic pain patients.
Download or read book Injuries of Nerves and Their Consequences written by Silas Weir Mitchell and published by . This book was released on 1872 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Pleasure Is All Yours written by Rachel Allyn and published by Shambhala Publications. This book was released on 2021-07-27 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reconnect to your inner sense of pleasure and joy through embodiment practices, which put you in touch with the natural wisdom of your body and enhance your ability to connect with others. In this time of increased fatigue, loneliness, and anxiety, disconnection from our bodies and from each other is at the core of our personal pain and our collective suffering. Women in particular are rewarded for, and expected to participate in self-denial. By weaving together historical and cultural commentary, humorous and poignant anecdotes, and experiential tools backed by science, The Pleasure Is All Yours is a step-by-step guide to help you release barriers to receiving life’s pleasures and deeper connections with others. In this timely guide, holistic psychologist, relationship and sex therapist, and yoga teacher Dr. Rachel Allyn introduces bodyfulness, an embodiment method she developed to help you to awaken into your body's own capacity for healing and deeper connection. Allyn explains how bodyfulness can connect you to four essential and overlooked types of pleasure—sensual, playful, lively, and erotic— which overlap in many ways, and helps you identify what can inspire your own pleasure in each category. Through bodyful activities such as breathing exercises, mindfulness, yoga, auditory release, and dynamic movements, this book helps you reunite with your inherent wisdom and soulful delight.
Download or read book Juta s Manual of Nursing written by Sophie Mataniele Mogotlane and published by Juta and Company Ltd. This book was released on 2003 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Back Pain written by J.K. Paterson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: As we stated in our message in the book of abstracts for this congress, we have planned the programme over a long period with one clear objective: to present musculoskeletal medicine as an integral part of orthodox medical practice, rather than as something alternative or complementary. To this end we have based the plenary programme as far as possible on accepted epidemiological, anatomical, physiological and pathological phenomena. Scientifically well-validated material must surely be the base upon which any viable musculoskeletal medicine practice may be built. While we have chosen the plenary programme to reflect musculoskeletal medicine as a part of orthodoxy, we realize and wish to emphasize that there is a wealth of original work that has been carried out within FIMM. For this reason our first innovation for the congress was to invite members of the scientific advisory committee to select for a 'directed' programme the three topics they felt were of greatest current importance. The results of this democratic procedure was the choice of the sacroiliac joint, a comparison of manual therapies and biomechanics. This illustrates the broad direction of present thinking within FIMM.
Download or read book Paradigms for the Study of Behavior written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 14: Paradigms for the Study of Behavior is a collection of articles that describes the methods for measuring a wide range of behavior. This volume covers the means for measuring different behaviors, such as reproductive, maternal, sexual, aggression, social interactions, feeding behavior, memory analysis, and classical conditioning. The opening papers outline the proper conditions and practical considerations in which the researcher can study the sexual and reproductive behavior of animals in the laboratory. Another paper describes how to assess aggressiveness in rodents including ethical issues involved in such study. The book then discusses the effects of intracerebral administration of neuropeptides in rats using surgical and stereotaxic methods. Another paper presents the measurement of behavioral thermoregulatory reflexes to show acuity of temperature sensation and thermoregulatory control. This volume also discusses the measurement of song-learning behavior in birds through ""sensorimotor,"" ""action-based,"" and ""sensory"" methods of learning. This book will be helpful for students, scientists, technicians, and laboratory workers whose work involves experiments that need to be accurately measured.
Download or read book Progress in Sensory Physiology written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the functional organization of the first synapse of the centripetal visual pathway at the outer plexiform layer level (OPL) ought to be made through the application of combined histological, electrophysiological, and neurochemical techniques. A large amount of new evidence has been accumu lated in the past 20 years on the structure of the retina and on the electrical responses of retinal cells to light stimulus. Also, recently, many substances considered as neurotransmitters in the brain have been found in the retina. The goal of the study of retinal function is to integrate the data obtained by structural and electrophysiological techniques and to identify and determine the role played by neurotransmitters or neuromodulators in the function of the retina. In this study it is important to realize the morphological and biochemical diversi ty displayed by the visual cells in the vertebrate retina which, according to Cresci telli (1972), has been produced "through the interaction of natural selection with diversity in the photic environment." The evidence obtained shows that bipolar and especially horizontal cells, closely related to visual cells, display morphologi cal and probably biochemical differences among classes, genus, and even species according to the photic environment. These differences give peculiarities to the organization of the OPL, which must be taken into account when studying a par ticular retina with electrophysiological or neurochemical techniques.
