Download or read book The Permeability of Natural Membranes written by Hugh Davson and published by . This book was released on 1952 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Permeability of Biological Membranes written by Gaspar Banfalvi and published by Springer. This book was released on 2018-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells. Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins. The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of irradiation. The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. The natural audience engaged in DNA research, including genetics, cell and molecular biology, chemistry, biochemistry, medicine, pharmacy will find essential material in the book.
Download or read book Cells Molecules and Mechanisms written by Eric Wong and published by Axolotl Academic Publishing. This book was released on 2009 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.
Download or read book Permeability of Biological Membranes written by Gaspar Banfalvi and published by Springer. This book was released on 2016-02-10 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells. Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins. The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of irradiation. The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. The natural audience engaged in DNA research, including genetics, cell and molecular biology, chemistry, biochemistry, medicine, pharmacy will find essential material in the book.
Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Download or read book Membrane Permeability 100 Years Since Ernest Overton written by and published by Academic Press. This book was released on 1999-05-21 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Provides an historical perspective of Overton's contributions to the theory of narcosis Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion
Download or read book Cellular Aspects of Membrane Permeability written by E. Schoffeniels and published by Elsevier. This book was released on 2017-09-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Aspects of Membrane Permeability describes the state of knowledge on permeability problems and interprets experimental results within the framework of working hypotheses. The book discusses membrane permeability with some biochemical perspective presented to explain the origin and adaptations of animal life. The text explains the process and the driving forces affecting the permeability characteristics of the experimental object. It then discusses the distribution of ions and molecules between two phases separated by a living membrane. Then the text analyzes the chemical nature of the molecular architecture that causes such permeability characteristics. The book addresses the electrical potential profiles of epithelial tissues, and then discusses the conducting membranes. It also explains the relationships between inorganic ions, sugar, amino acids, fatty acids, and bioelectric potentials. The book also explains the physical nature of such chemical nature and structure of living membranes. The text then describes the structure of the cellular surface and the structural organization of the cell. The selection can prove useful for biologists, microbiologists, zoologists, and students and professors of biology and its related disciplines.
Download or read book the permeability of natural membranes written by and published by CUP Archive. This book was released on with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Structure of Biological Membranes written by Philip L. Yeagle and published by CRC Press. This book was released on 2011-07-18 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro
Download or read book Membrane Hydration written by E. Anibal Disalvo and published by Springer. This book was released on 2015-10-05 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.
Download or read book Anatomy Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text
Download or read book Mesoscale Chemistry written by National Research Council and published by National Academies Press. This book was released on 2015-08-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few decades great strides have been made in chemistry at the nanoscale, where the atomic granularity of matter and the exact positions of individual atoms are key determinants of structure and dynamics. Less attention, however, has been paid to the mesoscale-it is at this scale, in the range extending from large molecules (10 nm) through viruses to eukaryotic cells (10 microns), where interesting ensemble effects and the functionality that is critical to macroscopic phenomenon begins to manifest itself and cannot be described by laws on the scale of atoms and molecules alone. To further explore how knowledge about mesoscale phenomena can impact chemical research and development activities and vice versa, the Chemical Sciences Roundtable of the National Research Council convened a workshop on mesoscale chemistry in November 2014. With a focus on the research on chemical phenomena at the mesoscale, participants examined the opportunities that utilizing those behaviors can have for developing new catalysts, adding new functionality to materials, and increasing our understanding of biological and interfacial systems. The workshop also highlighted some of the challenges for analysis and description of mesoscale structures. This report summarizes the presentations and discussion of the workshop.
Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Download or read book Membranes to Molecular Machines written by Mathias Grote and published by University of Chicago Press. This book was released on 2019-07-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences—from practitioner to historian to philosopher.
Download or read book Practical Medicinal Chemistry with Macrocycles written by Eric Marsault and published by John Wiley & Sons. This book was released on 2017-09-12 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
Download or read book The Giant Vesicle Book written by Rumiana Dimova and published by CRC Press. This book was released on 2019-11-19 with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference
Download or read book Blood Spinal Cord and Brain Barriers in Health and Disease written by Hari Shanker Sharma and published by Elsevier. This book was released on 2003-12-21 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro
