Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part A written by and published by Academic Press. This book was released on 2022-07-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome’s complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications. Examines Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating the Gilles de la Tourette Syndrome
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part B written by and published by Academic Press. This book was released on 2022-09-03 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part A written by and published by Academic Press. This book was released on 2022-07-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome's complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications.
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by Peristera Paschou and published by Frontiers Media SA. This book was released on 2018-03-13 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Download or read book Handbook of Tourette s Syndrome and Related Tic and Behavioral Disorders written by Roger Kurlan and published by CRC Press. This book was released on 2004-10-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on To
Download or read book Marsden s Book of Movement Disorders written by Ivan Donaldson and published by Oxford University Press. This book was released on 2012-03-29 with total page 1512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
Download or read book Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome written by and published by Academic Press. This book was released on 2013-11-27 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Download or read book Tourette Syndrome written by John T. Walkup and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes. Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Download or read book Pharmacological Treatment of Tics written by Andrea E. Cavanna and published by Cambridge University Press. This book was released on 2020-07-30 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of the assessment, diagnosis, and pharmacological treatment of tics, this is a practical handbook designed for use in busy clinics by trainees and practitioners in a range of disciplines. The most widely used pharmacological treatment options for tics are covered, including first- and second-generation antidopaminergic medications, alpha-2 adrenergic medications, and other tic-suppressing medications. Particular care has been taken in covering the key medications used for tic control, detailing information such as the main pharmacodynamic and pharmacokinetic properties, tolerability profiles, clinically relevant interactions, and recommendations for use in special populations. International guidelines on the pharmacotherapy of tics are defined, with further reading lists of up-to-date literature supporting the reader in developing their knowledge. Delivering evidence-based applied guidance for the assessment and pharmacological treatment of tics, this is an essential manual for clinicians.
Download or read book Hyperkinetic Movement Disorders written by Alberto Albanese and published by John Wiley & Sons. This book was released on 2012-03-07 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperkinetic movement disorders comprise a range of diseases characterized by unwanted and uncontrollable, or poorly controllable, involuntary movements. The phenomenology of these disorders is quite variable encompassing chorea, tremor, dystonia, myoclonus, tics, other dyskinesias, jerks and shakes. Discerning the underlying condition can be very difficult given the range and variability of symptoms. But recognizing the phenomenology and understanding the pathophysiology are essential to ensure appropriate treatment. Hyperkinetic Movement Disorders provides a clinical pathway for effective diagnosis and management of these disorders. The stellar international cast of authors distils the evidence so you can apply it into your practice. The judicious use of diagnostic criteria algorithms rating scales management guidelines Provides a robust framework for clear patient management. Throughout the text, QR codes* provide smartphone access to case-study videos of hyperkinetic symptoms. Purchase includes an enhanced Wiley Desktop Edition.* This is an interactive digital version featuring: all text and images in fully searchable form integrated videos of presentations View a sample video: www.wiley.com/go/albanese highlighting and note taking facilities book marking linking to additional references Hyperkinetic Movement Disorders provides you with the essential visual and practical tools you need to effectively diagnose and treat your patients. *Full instructions for using QR codes and for downloading your digital Wiley DeskTop Edition are inside the book.
Download or read book A Transdiagnostic Approach to Obsessions Compulsions and Related Phenomena written by Leonardo F. Fontenelle and published by Cambridge University Press. This book was released on 2019-01-03 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a transdiagnostic framework, this book describes how mental health professionals can diagnose and treat OCD and related disorder.
Download or read book Tourette Syndrome written by Thomas Newell Chase and published by Lippincott Williams & Wilkins. This book was released on 1992 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents an encyclopedic account of the past decade's achievements in the study and treatment of Tourette Syndrome (TS) and associated behavioral and psychiatric disorders. More than 90 of the foremost authorities from all relevant basic science, clinical, and behavioral science disciplines highlight the major recent developments worldwide - from groundbreaking genetic and neurochemical research and studies using state-of-the-art neuroimaging technologies, to new concepts on the clinical spectrum and natural history of TS, increasing recognition of comorbid conditions, and improved strategies for pharmacotherapy and psychosocial management. The contributors assess the practical utility of current diagnostic criteria for TS and present extensive data on its natural history, its range of clinical manifestations, and its associated disorders. The findings indicate that the severity of TS varies widely among patients, that tics tend to diminish during adolescence and adulthood, and that comorbid conditions - such as obsessive-compulsive disorder and attention deficit hyperactivity disorder - are often the chief source of impairment. Much evidence suggests that these disturbances and the tics are manifestations of the same underlying diathesis. Noted investigators document significant findings on the mode of inheritance for TS, define the key methodological issues in genetic linkage studies, and describe molecular approaches to the search for the genetic locus for the syndrome. The book also includes new data implicating specific monoamine neurotransmitters and endogenous opioid peptides in the pathogenesis of TS. Other contributors present neuroimaging studies using MRI, PET, and SPECT to delineate brain mechanisms involved in TS. The book offers definitive guidelines on pharmacotherapy for tics and, particularly, for associated obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). Of special note are the discussions on treatment of OCD with serotonin reuptake inhibitors and on use of clonidine and stimulants for ADHD with comorbid tics. Additional chapters explore the potential of novel drugs and of nutritional interventions such as megavitamin therapy. Full consideration is also given to the role of behavioral and psychosocial therapies and the educational management of children with TS. This volume is an indispensable resource for all clinicians and investigators involved in the treatment or study of neuropsychiatric disorders. It exemplifies the creative application of the full range of current neuroscience and behavioral methodologies to a complex and important syndrome.
Download or read book Schizo Obsessive Disorder written by Michael Poyurovsky and published by Cambridge University Press. This book was released on 2013-01-17 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.
Download or read book Oxford Textbook of Movement Disorders written by David Burn and published by Oxford University Press. This book was released on 2013-10 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the basic science and clinical concepts underlying the movement disorders, as well as the diagnosis and treatment of individual hypokinetic and hyperkinetic movement disorders.
Download or read book Managing Tourette Syndrome written by Douglas W. Woods and published by Oxford University Press. This book was released on 2008-08-20 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you suffer from Tourette Syndrome (TS), or any other chronic motor or vocal tic disorder, you know how difficult it can be to manage your symptoms. You may be taking medication or working with a medical doctor to control your tics. If you are seeking an alternative or adjunctive treatment, you may wish to try the scientifically proven behavior therapy program described in this workbook.Behavior therapy can teach you skills for effectively managing your tics. Designed to be used in conjunction with visits to a qualified mental health professional, this workbook outlines an 11-session treatment package for adults and children with tic disorders.Behavior therapy can teach you skills for effectively managing your tics. Designed to be used in conjunction with visits to a qualified mental health professional, this workbook outlines an 11-session treatment package for adults and children with tic disorders. The goal of this program is not to cure your disorder, but to teach you the best ways to manage it so that you can improve your quality of life and look to the future with optimism.TreatmentsThatWorkTM represents the gold standard of behavioral healthcare interventions! DT All programs have been rigorously tested in clinical trials and are backed by years of research DT A prestigious scientific advisory board, led by series Editor-In-Chief David H. Barlow, reviews and evaluates each intervention to ensure that it meets the highest standard of evidence so you can be confident that you are using the most effective treatment available to date DT Our books are reliable and effective and make it easy for you to provide your clients with the best care available DT Our corresponding workbooks contain psychoeducational information, forms and worksheets, and homework assignments to keep clients engaged and motivated DT A companion website (www.oup.com/us/ttw) offers downloadable clinical tools and helpful resources DT Continuing Education (CE) Credits are now available on select titles in collaboration with PsychoEducational Resources, Inc. (PER)
