Download or read book The Microstructural Border Between the Motor and the Cognitive Domain in the Human Cerebral Cortex written by Stefan Geyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last years, numerous studies have provided new insights into the structural and functional organization of the human cortical motor system. The data reviewed in this book indicate that striking similarities have been found between humans and non-human primates.

Download or read book Microstructural Parcellation of the Human Cerebral Cortex written by Stefan Geyer and published by Springer Science & Business Media. This book was released on 2013-07-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

Download or read book Brain Mapping written by and published by Academic Press. This book was released on 2015-02-14 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed

Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout

Download or read book Neuroanatomical Tract Tracing written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.

Download or read book Manual Asymmetries Handedness and Motor Performance written by Pamela Bryden and published by Frontiers Media SA. This book was released on 2016-06-10 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The performance of most tasks with one hand, typically the right, is a uniquely human characteristic. Not only do people prefer to use one hand rather than the other, but also they usually perform tasks faster and more accurately with this hand. The study of manual asymmetries and what such performance differences between the two hands reveal about brain organization and motor function has been a topic of considerable research over the last several decades. The aim of this Research Topic is to review and further explore the origins of manual asymmetries and their relationship to handedness, unimanual and bimanual motor performance, and brain function. The articles included here involve original research conducted in humans or non-human models species, as well as theoretical perspectives, review articles, and meta-analyses.

Download or read book Clinical Neuroanatomy written by Hans J. ten Donkelaar and published by Springer Nature. This book was released on 2020-06-18 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death can progress through connections. Accordingly, knowing how the various parts of the brain are interconnected to form functional systems is a prerequisite for properly understanding data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It focuses on human and primate data in the context of brain circuitry disorders, which are so common in neurological practice. In addition, numerous clinical cases are presented to demonstrate how normal brain circuitry can be interrupted, and what the effects are. Following an introduction to the organization and vascularization of the human brain and the techniques used to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions. In this 2nd edition, apart from a general updating, many new illustrations have been added and more emphasis is placed on modern techniques such as diffusion magnetic resonance imaging (dMRI) and network analysis. Moreover, a developmental ontology based on the prosomeric model is applied, resulting in a more modern subdivision of the brain. The new edition of Clinical Neuroanatomy is primarily intended for neurologists, neuroradiologists and neuropathologists, as well as residents in these fields, but will also appeal to (neuro)anatomists and all those whose work involves human brain mapping.

Download or read book Understanding the Prefrontal Cortex written by Richard Passingham and published by Oxford University Press. This book was released on 2021-06-03 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: A successor to the acclaimed 'Neurobiology of the Prefrontal Cortex', 'Understanding the Prefrontal Cortex' presents a careful study of the anatomical connections in this brain region, showing how each area and subarea of the brain has a unique pattern of connections, and exploring the transformation that this area performs - from its inputs to it outputs. The book starts with two chapters of foundational material, before considering five subdivisions of the prefrontal cortex, and looking at the transformation that each one performs. Next it considers how the prefrontal cortex interacts with the rest of the brain, including not only cortical areas but also subcortical areas such as the basal ganglia and cerebellum. The book ends with a final section in which these principles are applied to the human brain. It starts by discussing the expansion of the prefrontal cortex during human evolution. It then considers how the human brain has co-opted mechanisms that existed in our primate ancestors, and by providing new inputs had extended them so as to support reasoning, remembering events from the distant past and imagining events in the distant future, the sense of self, language, the ability to understand the mental states of others, and the ability to cooperate and learn social and moral rules. Written by a leading brain scientist, the book will be an important and influential contribution to the neuroscience literature.

Download or read book Neuroimaging written by Sanja Josef Golubic and published by BoD – Books on Demand. This book was released on 2019-04-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging provides a valuable noninvasive window into the human neural system and is used in fundamental and clinical research. Imaging techniques are essential for understanding spontaneous neural activity and brain mechanisms engaged in the processing of external inputs, memory formation, and cognition. Modern imaging modalities make it possible to visualize memory processes within the brain and to create images of its structure and function. Scientists and technologists are joining forces to pave the way for improving imaging technologies and methods, data analysis, and the application of imaging to investigate the wide spectra of neurological diseases, neuropsychological disorders, and aging. Imaging techniques are essential for the identification of biological markers of the earliest stages of neurodiseases and the development of new therapies. This book intends to provide the reader with a short overview of the current achievements in the state-of-the-art imaging modality methods, their highlights, and limitations in neuroscience research and clinical applications. The current state of in-vivo neuroimaging methods in the context of the understanding and diagnosis of mental disorders and relation to the mind is also discussed in a modern compact format, featuring the latest and most relevant research results.

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Download or read book The Frontal Lobes written by and published by Academic Press. This book was released on 2019-10-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders. - Provides an overview of the structure, function, disorder and rehabilitation of the frontal lobes - Addresses a wide variety of methodologies – from genetics and molecular biology, to optogenetics and hi-res fMRI, and more - Contains content of interest to advanced students, junior researchers and clinicians getting involved in research - Features the input of leaders in neuroanatomical research from around the globe – the broadest, most expert coverage available

Download or read book Neuroanatomy for the XXIst Century written by Kathleen S. Rockland and published by Frontiers Media SA. This book was released on 2016-08-15 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting.

Download or read book What makes written words so special to the brain written by Gui Xue and published by Frontiers E-books. This book was released on 2015-01-22 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reading is an integral part of life in today’s information-driven societies. Since the pioneering work of Dejerine on “word blindness” in brain-lesioned patients, the literature has increased exponentially, from neuropsychological case reports to mechanistic accounts of word processing at the behavioural, neurofunctional and computational levels, tapping into diverse aspects of visual word processing. These studies have revealed some exciting findings about visual word processing, including how the brain learns to read, how changes in literacy impact upon word processing strategies, and whether word processing mechanisms vary across different alphabetic, logographic or artificial writing systems. Other studies have attempted to characterise typical and atypical word processes in special populations in order to explain why dyslexic brains struggle with words, how multilingualism changes the way our brains see words, and what the exact developmental signatures are that would shape the acquisition of reading skills. Exciting new insights have also emerged from recent studies that have investigated word stimuli at the system/network level, by looking for instance, at how the reading system interacts with other cognitive systems in a context-dependent fashion, how visual language stimuli are integrated into the speech processing streams, how both left and right hemispheres cooperate and interact during word processing, and what the exact contributions of subcortical and cerebellar regions to reading are. The contributions to this Research Topic highlight the latest findings regarding the different issues mentioned above, particularly how these findings can explain or model the different processes, mechanisms, pathways or cognitive strategies by which the human brain sees words. The introductory editorial, summarising the contributions included here, highlights how varieties of behavioural tests and neuroimaging techniques can be used to investigate word processing mechanisms across different alphabetic and logographic writing systems.

Download or read book Neuroimaging Studies of the Role of Speech Motor Areas in Speech Perception written by Stephen Murray Wilson and published by . This book was released on 2006 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The neurobiology of emotion cognition interactions written by Hadas Okon-Singer and published by Frontiers Media SA. This book was released on 2015-06-12 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is increasing interest in understanding the interplay of emotional and cognitive processes. The objective of the Research Topic was to provide an interdisciplinary survey of cutting-edge neuroscientific research on the interaction and integration of emotion and cognition in the brain. The following original empirical reports, commentaries and theoretical reviews provide a comprehensive survey on recent advances in understanding how emotional and cognitive processes interact, how they are integrated in the brain, and what their implications for understanding the mind and its disorders are. These works encompasses a broad spectrum of populations and showcases a wide variety of paradigms, measures, analytic strategies, and conceptual approaches. The aim of the Topic was to begin to address several key questions about the interplay of cognitive and emotional processes in the brain, including: what is the impact of emotional states, anxiety and stress on various cognitive functions? How are emotion and cognition integrated in the brain? Do individual differences in affective dimensions of temperament and personality alter cognitive performance, and how is this realized in the brain? Are there individual differences that increase vulnerability to the impact of affect on cognition—who is vulnerable, and who resilient? How plastic is the interplay of cognition and emotion? Taken together, these works demonstrate that emotion and cognition are deeply interwoven in the fabric of the brain, suggesting that widely held beliefs about the key constituents of ‘the emotional brain’ and ‘the cognitive brain’ are fundamentally flawed. Developing a deeper understanding of the emotional-cognitive brain is important, not just for understanding the mind but also for elucidating the root causes of its many debilitating disorders.

Download or read book Why and How is the self related to the brain midline regions written by Georg Northoff and published by Frontiers E-books. This book was released on 2014-09-26 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: What the self is and where it comes from has been one of the great problems of philosophy for thousands of years. As science and medicine have progressed this question has moved to also become a central one in psychology, psychiatry, and neuroscience. The advent of in vivo brain imaging has now allowed the scientific investigation of the self to progress further than ever. Many such imaging studies have indicated that brain structures along the cortical midline are particularly closely related to self-specific processing. This association between cortical midline structures (CMS) and self is reinforced by the involvement of these regions in other self-oriented processes, such as mind-wandering or stimulus valuation. Those midline regions involved in self- processing also overlap with another network, the default mode network, which shows high brain activity during the so-called resting state, indicating that there may be a special relationship between self-processing and intrinsic activity. Although such promising groundwork linking the self and CMS has been carried out, many questions remain. These include: what features of the midline regions lead to their apparent importance in self-processing? How can we appropriately account for confounding factors such as familiarity or task-effects in our experiments? How is the self-related to other features of the mind, such as consciousness? How is our methodology influencing our attempts to link the self and the brain? The purpose of this ebook is to address some of these questions, including opinions, perspectives, and hypotheses about the concept of the self, the relationship between CMS and the self, and the specific function of these brain regions in self-processing. It also includes original research papers describing EEG, fMRI, and behavioral experiments investigating different aspects of the self.

Download or read book Broca s Region written by Yosef Grodzinsky and published by Oxford University Press. This book was released on 2006-04-20 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Broca's region has been in the news ever since scientists realized that particular cognitive functions could be localized to parts of the cerebral cortex. Its discoverer, Paul Broca, was one of the first researchers to argue for a direct connection between a concrete behavior--in this case, the use of language--and a specific cortical region. Today, Broca's region is perhaps the most famous part of the human brain, and for over a century, has persisted as the focus of intense research and numerous debates. The name has even penetrated mainstream culture through popular science and the theater. Broca's region is famous for a good reason: As language is one of the most distinctive human traits, the cognitive mechanisms that support it and the tissues in which these mechanisms are housed are also quite complex, and so have the potential to reveal a lot not only about how words, phrases, sentences, and grammatical rules are instantiated in neural tissue, but also, and more broadly, about how brain function relates to behavior. Paul Broca's discoveries were an important, driving force behind the more general effort to relate complex behavior to particular parts of the cerebral cortex, which, significantly, produced the first brain maps.These early studies also, however, suffered from the use of crude techniques, definitions, and distinctions, as well as from ill founded and misdirected assumptions. Although much has been discovered since Broca's work, even today, these problems have not been completely solved. Nonetheless, particularly as a result of important advances made in neuroimaging during the past two decades, Broca's region and all language areas are currently being investigated from every angle. Indeed, as the volume of research into the relations between brain and language has created several communities, each with its own concepts, methods, and considerations, it seemed that it was time to stop, get together, and reflect on the state of the art.This book is the result of that collective reflection, which took place primarily at the Broca's Region Workshop, held in Julich and Aachen, Germany, in June 2004. In it, Yosef Grodzinsky and Katrin Amunts tried to accomplish a nearly impossible task: to mix intellectual traditions and cultures, and juxtapose rather disparate bodies of knowledge, styles of reasoning, and forms of argumentation. Participants were scientists with diverse backgrounds; each invited to contribute his/her particular take, with the hope that a coherent, perhaps even novel, picture would emerge. All of the participants have a special interest in Broca's Region, and represent the myriad angles from which we currently approach it: neuroanatomy, physiology, evolutionary biology, cognitive psychology, clinical neurology, functional imaging, speech and language research, computational biology, and psycho-, neuro-, and theoretical linguistics. The book's main chapters are the contributions of the Workshop's participants and their research teams. Parts of the discussion during the Workshop are included to underscore the richness of viewpoints, and to give readers an idea of the level of interaction that took place. As Broca's region is such a historically significant concept and rich area, this book contains a collection of classic and recent-yet-classic papers. Along with cutting-edge science, Grodzinsky and Amunts want to remind readers of the celebrated past from which much can be learned. The historical chapters include the first two papers written by Paul Broca, as well some work by two of the most important neurologists of the nineteenth century, Ludwig Lichtheim and John Hughlings-Jackson. Also included are parts of twentieth century papers by Korbinian Brodmann, Roman Jakobson, Norman Geschwind, Harold Goodglass, and Jay Mohr. Because this book both reflects the state of the art in Broca's-region research and contains a tribute to its celebrated past, it will be a valuable resource for student and professional researchers. It will also stimulate further interdisciplinary research, which is a significant contribution, as the project called "Broca's region," encompassing the study of brain/language relations, is far from finished.