Download or read book The Mathematical Theory of Quantitative Genetics written by Michael George Bulmer and published by Clarendon Press. This book was released on 1985 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes discussion of the underlying principles of the theory of quantitative genetics which provides the bridge between the observable statistical properties of a character and the gentic factors, which together with environmental factors, determine the expression of the character. "An essential reference for anyone concerned with quantitative genetics. . . . Provides the only review available of the parts of quantitative genetics relevant to evolutionary theory."--Science

Download or read book The Mathematical Theory of Quantitative Genetics written by M. G. Bulmer and published by . This book was released on 1985 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Mathematical Theory of Selection Recombination and Mutation written by R. Bürger and published by John Wiley & Sons. This book was released on 2000-11-02 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: "It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail. * Provides a unified, self-contained and in-depth study of the theory of multilocus systems * Introduces the basic population-genetic models * Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection * Summarizes important results from more demanding sections in a comprehensible way * Employs a clear and logical presentation style Following an introduction to elementary population genetics and discussion of the general theory of selection at two or more loci, the author considers a number of mutation-selection models, and derives the dynamical equations for polygenic traits under general selective regimes. The final chapters are concerned with the maintenance of quantitative-genetic variation, the response to directional selection, the evolutionary role of deleterious mutations, and other topics. Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in-depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology.

Download or read book Evolution and Selection of Quantitative Traits written by Bruce Walsh and published by Oxford University Press. This book was released on 2018-06-21 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Download or read book Evolutionary Quantitative Genetics written by Derek A. Roff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.

Download or read book Introduction to Quantitative Genetics written by D. S. Falconer and published by Createspace Independent Publishing Platform. This book was released on 2017-08-07 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: My aim in writing this book has been to provide an introductory textbook of quantitative genetics, with the emphasis on general principles rather than on practical application, and one moreover that can be understood by biologists of no more than ordinary mathematical ability. In pursuit of this latter aim I have set out the mathematics in the form that I, being little of a mathematician, find most comprehensible, hoping that the consequent lack of rigour and elegance will be compensated for by a wider accessibility. The reader is not, however, asked to accept conclusions without proof. Though only the simplest algebra is used, all the mathematical deductions essential to the exposition of the subject are demonstrated in full. Some knowledge of statistics, however, is assumed, particularly of the analysis of variance and of correlation and regression. Elementary knowledge of Mendelian genetics is also assumed.

Download or read book Quantitative Genetics written by Armando Caballero and published by Cambridge University Press. This book was released on 2020-04-23 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, accessible guide to the main concepts and applications of quantitative genetics.

Download or read book Quantitative Genetics Explanation and analysis of continuous variation written by William G. Hill and published by Van Nostrand Reinhold Company. This book was released on 1984 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Download or read book The Mathematical Theory of Quantitatives Genetics written by M. G. Bulmer and published by . This book was released on 1980 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Introduction to Quantitative Genetics Classic Reprint written by D. S. Falconer and published by Forgotten Books. This book was released on 2017-10-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Introduction to Quantitative Genetics I have had no particular class of reader exclusively in mind, but have tried to make the book useful to as wide a range of readers as possible. In consequence some will find less detail than they require and others more. Those who intend to become specialists in this branch of genetics or in its application to animal or plant breeding will find all they require of the general principles, but will find little guidance in the techniques of experimentation or of breeding practice. Those for whom the subject forms part of a course of general genetics will find a good deal more detail than they require. The section headings, however, should facilitate the selection of what is relevant, and any of the following chapters could be omitted without serious loss of continuity: Chapters 4, 5, 10 (after p. 12, 13, and I 5 - 20. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Download or read book Introduction to the Mathematical Theory of Genetic Linkage written by Norman T. J. Bailey and published by . This book was released on 1961 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genes Environments and Interactions written by José M Álvarez-Castro and published by Springer Nature. This book was released on 2024-01-18 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.

Download or read book Population Genetics written by W.J. Ewens and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Population genetics is the mathematical investigation of the changes in the genetic structure of populations brought about by selection, mutation, inbreeding, migration, and other phenomena, together with those random changes deriving from chance events. These changes are the basic components of evolutionary progress, and an understanding of their effect is therefore necessary for an informed discussion of the reasons for and nature of evolution. It would, however, be wrong to pretend that a mathematical theory, depending as it must on a large number of simplifying assump tions, should be accepted unreservedly and that its conclusions should be accepted uncritically. No-one would pretend that in the event of disagreement between observation and mathematical prediction, the discrepancy is due to anything other than the inadequacy of the mathematical treatment. The biological world is, of course, far too complex for the study of population genetics to be simply a branch of applied mathematics, so that while we are concerned here with the mathematical theory, I have tried to indicate which of our results should continue to apply in a context wider than that in which they are formally derived. The difficulties involved in the joint discussions of mathematical and genetical problems are obvious enough. I have tried to aim this book rather more at the mathematician than at the geneticist, and for this reason a brief glossary of common genetical terms is included.

Download or read book Genetical Analysis of Quantitative Traits written by Dr M Kearsey and published by Garland Science. This book was released on 2020-10-29 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a guide to the experimental and analytical methodologies available to study quantitative traits, a review of the genetic control of quantitative traits, and a discussion of how this knowledge can be applied to breeding problems and evolution.

Download or read book Quantitative Genetics Genomics and Plant Breeding 2nd Edition written by Manjit S. Kang and published by CABI. This book was released on 2020-04-01 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art, authoritative chapters on contemporary issues in the broad areas of quantitative genetics, genomics and plant breeding. Section 1 (Chapters 2 to 12) emphasizes the application of genomics, and genome and epigenome editing techniques, in plant breeding; bioinformatics; quantitative trait loci mapping; and the latest approaches of examining and exploiting genotype-environment interactions. Section 2 (Chapters 13 to 20) represents the intersection of breeding, genetics and genomics. This section describes the use of cutting-edge molecular breeding and quantitative genetics techniques in wheat, rice, maize, root and tuber crops and pearl millet. Overall, the book focuses on using genomic information to help evaluate traits that can combat biotic/abiotic stresses, genome-wide association mapping, high-throughput genotyping/phenotyping, biofortification, use of big data, orphan crops, and gene editing techniques. The examples featured are taken from across crop science research and cover a wide geographical base.