Download or read book The Influence of Dietary Protein Concentration and Energy Intake on Energy Utilization in Melanoma bearing Mice written by Karen Lee Freiburger and published by . This book was released on 1979 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Interactions Between Dietary Concentrations of Protein and Fat Upon Utilization of Energy by Mice Selected for Rapid Postweaning Growth Rate written by Linda White Geiger and published by . This book was released on 1977 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Influence of Dietary Protein Concentration on the Utilization of Energy for Fat and Lean Gains written by Timothy Jon Riordan and published by . This book was released on 1977 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Influence of Dietary Protein Concentration and Energy Intake on Body Composition of Lactating Rats and Their Progeny written by Mandeep Kaur Bindra and published by . This book was released on 1982 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dietary Energy Balance Modulates Growth Factor Signaling During Multistage Epithelial Carcinogenesis in Mouse Skin written by Tricia Wallace Moore and published by . This book was released on 2010 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Energy balance refers to the relationship between energy intake and energy expenditure. Epidemiological studies have established a clear association between energy balance and cancer, however the underlying mechanisms are unclear. The objective of the current study was to evaluate the impact of caloric consumption on epithelial carcinogenesis and identify potential mechanisms of inhibition or enhancement. Using ICR female mice, we demonstrated that positive energy balance enhanced, while negative energy balance inhibited susceptibility to multistage carcinogenesis in mouse skin. We next evaluated diet-induced changes in the epidermal proliferative response. Calorie restriction (CR) significantly reduced epidermal hyperproliferation, in the presence and absence of tumor promotion, as compared to diet-induced obesity (DIO). Additional studies were conducted to determine the impact of dietary manipulation on TPA-induced growth factor signaling. CR reduced, while DIO increased insulin like growth factor-1 receptor (IGF-1R) and epidermal growth factor receptor (EGFR) activation, which subsequently modulated signaling downstream to Akt and mTOR. These diet-induced changes in growth factor signaling were confirmed under steady-state conditions in multiple epithelial tissues (i.e., skin, liver and dorsolateral prostate) in multiple mouse strains (FVB/N, C57BL/6 and ICR). Further analyses demonstrated that caloric consumption directly correlated with levels of cell cycle progression related proteins and inversely correlated with levels of cell cycle inhibitory proteins. Genetic reduction of circulating IGF-1, liver IGF-1 deficient (LID) mouse model, inhibited two-stage skin carcinogenesis, reduced epidermal hyperproliferation and attenuated IGF-1R and EGFR growth factor signaling during tumor promotion, similar to CR, suggesting a potential for IGF-1R and EGFR crosstalk. Further studies, demonstrated that IGF-1 induced EGFR activation in cultured mouse keratinocytes, possibly due to IGF-1R and EGFR heterodimerization or IGF-1 induced changes in EGFR mRNA expression. In vivo, CR reduced, while DIO increased IGF-1R and EGFR association during tumor promotion. Furthermore, CR attenuated EGFR ligand mRNA expression both in the presence and absence of TPA treatment. Collectively, these findings suggest that dietary energy balance modulates epithelial carcinogenesis, at least in part due to diet-induced changes in levels of circulating IGF-1, which then modulate IGF-1R and EGFR crosstalk and downstream signaling to cell cycle related proteins, subsequently altering epidermal hyperproliferation.

Download or read book The Effect of Dietary Protein on Energy Utilization written by Donald Carl Bedell and published by . This book was released on 1966 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nutrition Abstracts and Reviews written by and published by . This book was released on 1995 with total page 2230 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Agrindex written by and published by . This book was released on 1981 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Effect of Diet on Tumour Development in Animals written by Ulrich Mohr and published by Wiley-VCH. This book was released on 1989 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: An analysis of the fundamental question of whether diet plays a role in the development of cancer. This study compiles the latest animal research data emphasizing the major dietary components such as fat, protein and amino acids, carbohydrates, and fibers as well as antioxidants and aflatoxins. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Commencement Ceremony written by University of California, Davis. Graduate Division and published by . This book was released on 1976 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Experimentelle Pathologie written by and published by . This book was released on 1989 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biological Agricultural Index written by and published by . This book was released on 1980 with total page 1768 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bibliography of Agriculture written by and published by . This book was released on 1975 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bibliography of Agriculture written by and published by . This book was released on 1985 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bibliography of Agriculture with Subject Index written by and published by . This book was released on 1982 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Practical Medical Oncology Textbook written by Antonio Russo and published by Springer Nature. This book was released on 2021-10-06 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.