Download or read book The Immunological Basis of Asthma written by Bart Lambrecht and published by CRC Press. This book was released on 2003-02-26 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text assesses the role of dendritic cells, T and B lymphocytes, epithelial and mast cells, eosinophils, neutrophils, macrophages, and their products in the initiation and progression of airway inflammation, regulation, and repair. It unveils advances in immunology and cell biology to generate new therapeutic regimens for inflammatory and aller
Download or read book The Biochemical and Immunological Basis of Bronchial Asthma written by Kjell Aas and published by Charles C. Thomas Publisher. This book was released on 1972 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunological Mechanisms in Asthma and Allergic Diseases written by Douglas S. Robinson and published by Karger Medical and Scientific Publishers. This book was released on 2000-01-01 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the cellular and molecular mechanisms involved in asthma and allergic diseases, from basic immunology to the treatment of patients. Arising from a special symposium held to celebrate Professor A. Barry Kay's 20th anniversary as Head of the Department of Allergy and Clinical Immunology at the National Heart and Lung Institute, London, the publication presents 18 review articles by an impressive cross section of experts in the field. Topics considered include Th1 and Th2 cells, the regultion of Th2 cytokine transcription, the role of T cells in the immunopathogenesis of asthma, and MHC-restricted IgE-independent T-cell-induced late-phase responses in human subjects. Further chapters focus on eosinophil adhesion and activation, the role of C-C chemokines in the recruitment of eosinophils, and the interactions between eosinophils and fibroblasts. T-cell recruitment and T-cell interactions in cutaneous basophil hypersensitivity and fibrotic lung disease are discussed, as is the molecular pathology of allergic disease. Finally, treatment approaches are considered in chapters on the molecular basis of corticosteroid actions in asthma, immunosuppression in asthma, and immunotherapy of allergic diseases.
Download or read book The Hereditary Basis of Allergic Diseases written by Stephen T. Holgate and published by Birkhäuser. This book was released on 2012-12-06 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.
Download or read book Human Eosinophils written by Gianni Marone and published by Karger Medical Scientific. This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The well-edited and stimulating material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine.
Download or read book Biochemical and Immunological Basis of Asthma written by Benget Bjorkoten and published by . This book was released on 1985 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Allergic Asthma Immunopathogenesis written by Seyyed Shamsadin Athari and published by Elsevier. This book was released on 2024-05-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a chronic complicated airway disease whose mortality and morbidity rates have increased worldwide. Some common treatments for asthma cannot control it nor even prevent simple inflammation and relieve shortness of breath, so understanding its molecular pathways and pathophysiology is required in order to better understand the disease and to diagnose, control and treat it. Allergic Asthma Immunopathogenesis: Immunopathology of the Allergic Asthma presents a new glance to the allergic asthma pathophysiology by focusing on the immunopathogenesis and allergo-inflammation mechanisms of asthma and cell signaling pathways that can be used for various research purposes, including the design of anti-asthma treatment and target therapy for scientists and researchers. Covers new molecular pathophysiology mechanisms and cell signaling pathways in pathogenesis of allergic asthma that have been introduced in recent research Discusses immunologic basis of the allergy and hyperresponsiveness Includes results of recent research focusing on the diagnosis and treatment of allergic asthma
Download or read book Asthma written by Friedrich Kummer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die strukturellen Veränderungen der Bronchialschleimhaut beim Asthma sind zwar Folge der zellulären Interaktionen, aber wesentlich träger als diese und bilden die Basis für später irreversible Funktionsstörungen. Daher ist die frühe antientzündliche Therapie so wichtig. Für diese wieder scheint das Theophyllin zunehmend interessant zu werden, wie aus neuesten in vitro und in vivo Untersuchungen hervorgeht.
Download or read book Biochemical and Immunological Basis of Bronchial Asthma written by Kjell Aas and published by . This book was released on 1981 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Download or read book Asthma Health and Society written by Andrew Harver and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma, Health, and Society A Public Health Perspective Edited by Andrew Harver, University of North Carolina at Charlotte, Charlotte Harry Kotses, Ohio University, Athens Asthma, Health, and Society is a comprehensive, current resource on this complex disease—its scope, human costs, and management—from a combined social ecology/public health perspective. This important and unique book proposes a concerted, multifaceted response and sets out the foundation for shaping this response, comprising individual and large-scale assessment, education, advocacy, and multiple forms of intervention. In clear, authoritative detail enhanced by figures, graphs, and references, contributors explain where universal standards need to be set, alliances need to be built (such as among agencies and institutions in a community), and what is currently known about: Pathophysiology, epidemiology, and social impact of asthma. Genetic and environmental factors; protective factors and risk markers. Effects in women, minorities, children, teens, and elders. Medical management, self-management, and home monitoring. Evidence-based interventions at the family, school, and community levels. Screening guidelines, compliance issues, and more. In the absence of a cure or clear-cut causes, Asthma, Health, and Society offers the most robust compilation of practical knowledge on its subject to benefit the range of public health and asthma professionals, researchers, teachers, and students
Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.
Download or read book Oxidative Stress in Lung Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-08-31 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Download or read book Asthma written by Magdalena M. Gorska and published by Springer Nature. This book was released on 2022-06-30 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a collection of laboratory protocols to study asthma in mice and humans. Chapters cover animal models of asthma, methods to measure asthma-related molecules, protocols to detect, isolate, culture and stimulate cells that contribute to asthma in mice and humans, methods to deplete these cells in vivo and study responses of intact airway tissues ex vivo. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Asthma: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Download or read book Indoor Allergens written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and schoolâ€"where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.
Download or read book Asthma written by Celso Pereira and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a prevalent disease in all age groups that results from different pathogenic mechanisms, cells, and mediators engaged in innumerous clinical phenotypes and endotypes. This book exhaustively and didactically explores the biological expression of numerous cells and mediators involved in bronchial inflammation. The information provided aims at identifying the diversity and complexity of the interrelationships between the different players, drawing attention to critical mechanisms in asthma. It also highlights the requirement of new tools to identify strong biomarkers absolutely critical for managing asthma.
Download or read book Allergy and Allergic Diseases written by A. Barry Kay and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 2184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reserve your copy now This two volume book is an outstanding reference source on allaspects of allergy and allergic diseases. Covering virtually everyallergic condition, from the immunological and molecular basis ofthe allergic response to future trends in allergic diseaseprevention, this new international editorial team (A.B.Kay, JeanBousquet, Pat Holt and Allen Kaplan) have completely revised andupdated the text, from both a scientific and clinical perspective.References will continue to be added to the text until it goes topress making this the most up-to-date book available in thefield. This second edition consists of more than 1,800 pages containedwithin 98 chapters. The price includes a fully searchable companion CD ROM with thecomplete text and over 300 images from the book in full colour.
