Download or read book Human Retroviruses written by Bryan Cullen and published by Oxford University Press. This book was released on 1993 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Download or read book The Human Retroviruses written by Robert C. Gallo and published by Elsevier. This book was released on 2012-12-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents twenty-four tightly focused reviews on the biology, molecular biology, pathology, and epidemiology of the human retroviruses, particularly HIV and HTLV (Types I and II), as well as animal model systems (simian retroviruses, STLV and SIV, and mouse models).Editor Robert C. Gallo is recognized as a co-discoverer of the AIDS virus.
Download or read book Retroviruses written by John M. Coffin and published by CSHL Press. This book was released on 1997 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Download or read book Human Retroviruses and Diseases They Cause written by Jean-Pierre Allain and published by . This book was released on 1988 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transacting Functions of Human Retroviruses written by Irvin S.Y. Chen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Download or read book Virus Hunting written by Robert C. Gallo and published by . This book was released on 1991-05-15 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the discovery of AIDS and other notable discoveries, Gallo's investigation by the NIH, and provides a personal chronicle of the scientist's life.
Download or read book Human Retrovirus Protocols written by Tuofu Zhu and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge collection of basic and state-of-the-art methods optimized for investigating the molecular biology of this class of retrovirus. These readily reproducible techniques range from methods for the isolation and detection of human retroviruses to cutting-edge methods for exploring the interplay between the viruses and the host. Here, the researcher will find up-to-date techniques for the isolation and propagation of HIV, HTLV, and foamy virus from a variety of sources. There are also assays for determining the cell tropism of HIV-1, the coreceptor usage of HIV-1, and human gene expression with HIV-1 infection by microarrays, as well as for phenotyping HIV-1 infected monocytes and examining their fitness. Highlights include the detection and quantification of HIV-1 in resting CD4+, a new cloning system for making recombinent virus, cDNA microarrays, and the determination of genetic polymorphisms in two recently identified HIV-1 co-factors that are critical for HIV-1 infection.
Download or read book Human Retrovirology written by Jörg Schüpbach and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a concise review of the known human retroviruses; the onco-retroviruses HTLV-1 and -2 and the AIDS-associated lentiviruses HIV-1 and -2. History, classification, general and genomic structure, and basic biologic facts of retroviruses are described in introductory chapters. Subsequent chapters deal with the epidemiology, disease spectrum, structure and functions of the viral genes and proteins of the individual viruses. A separate chapter describes the various humoral and cellular immune mechanisms in response to HIV and their use with respect to diagnosis and treatment. Special attention is given to the complicated pathogenesis of AIDS and the consequences with regard to therapy and vaccination. The book ends with a critical review of recent work suggesting a possible role of still other retroviruses in human disorders including malignancies, autoimmune, or neurologic diseases. The book is designed to give the reader a broad, but detailed view of human retroviruses and the diseases associated with them. It tries to connect the viral, immunologic, and pathologic aspects of these infections to unifying concepts - no quick answers though, but profound critical information on a complicated topic.
Download or read book Discovering Retroviruses written by Anna Marie Skalka and published by Harvard University Press. This book was released on 2018-10-15 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately eight percent of our DNA contains retroviral sequences that are millions of years old. Through engaging stories of scientific discovery, Anna Marie Skalka explains our evolving knowledge of these ancient denizens of the biosphere and how this understanding has significantly advanced research in genetic engineering, gene delivery systems, and precision medicine. Discovering Retroviruses begins with the pioneer scientists who first encountered these RNA-containing viruses and solved the mystery of their reproduction. Like other viruses, retroviruses invade the cells of a host organism to reproduce. What makes them “retro” is a unique process of genetic information transfer. Instead of transcribing DNA into RNA as all living cells do, they transcribe their RNA into DNA. This viral DNA is then spliced into the host’s genome, where the cell’s synthetic machinery is co-opted to make new virus particles. The 100,000 pieces of retroviral DNA in the human genome are remnants from multiple invasions of our ancestors’ “germline” cells—the cells that allow a host organism to reproduce. Most of these bits of retroviral DNA are degenerated fossils, but some have been exploited during evolution, with profound effects on our physiology. Some present-day circulating retroviruses cause cancers in humans and other animals. Others, like HIV, cause severe immunodeficiencies. But retroviruses also hold clues to innovative approaches that can prevent and treat these diseases. In laboratories around the world, retroviruses continue to shed light on future possibilities that are anything but “retro.”
Download or read book Plague written by Kent Heckenlively and published by Simon and Schuster. This book was released on 2017-02-21 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 22, 2009, a special meeting was held with twenty-four leading scientists at the National Institutes of Health to discuss early findings that a newly discovered retrovirus was linked to chronic fatigue syndrome (CFS), prostate cancer, lymphoma, and eventually neurodevelopmental disorders in children. When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, “Oh my God!” The resulting investigation would be like no other in science. For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid. On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.
Download or read book Retroviruses and Disease written by Hidesaburo Hanafusa and published by Elsevier. This book was released on 2012-12-02 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retroviruses and Disease presents a relevant summary of the state of knowledge in both human nonhuman retroviruses. It highlights significant concepts regarding their commonalities and differences in terms of retroviral systems. A section of this book covers the pathogenic human retroviruses and focuses on two. These are HLTV-1 (the first human retrovirus that was isolated) and HIV (the cause of a potent immunological disorder). The life cycle of replication-competent retroviruses, including the murine leukemia viruses and its functions, is discussed in Chapters 1 and 2. The focus of the third chapter is the transformation of Rous sarcoma virus. Meanwhile, Chapter 4 discusses the multiple stages in avian leukosis virus-induced B cell lymphoma. Oncogenes, the molecular basis of human cancer, are also covered in this book. Another virus also discussed in this book is the human T cell leukemia virus. The book is a good reference for students, teachers, specialists, scientists, and researchers in microbiology.
Download or read book Retrovirus Infections of the Nervous System written by Michael B.A. Oldstone and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although retroviruses have long been associated with a variety of animal diseases, active research in the field of human retroviruses dates from the discovery of human immunodefici ency virus (HIV) in association with acquired immunodefici ency syndrome (AIDS). The enormous research efforts in this field have been directed toward understanding the nature of the virus and toward its elimination through preventive vaccin ation and the cure of the disease. Human T-cell leukemia virus (HTLV-l) was the first member of the human retrovirus family to be discovered. It was implicated as the cause of adult T-cell leukemia (ATL) even before the association of HIV and AIDS was established. Research on HTL V -1 has, however, been lagging behind that of HIV because of the importance of AIDS. Today HTLV-1 and possibly closely related HTLV-2 are associated with a variety of human neurologic diseases, and research activities in this field may show that human retroviruses can cause a variety of human diseases in addition to those affecting the nervous system. Papers in this volume attempt to acquaint the reader with the present state of research into retrovirus infection and related diseases of the nervous system.
Download or read book AIDS Research and Human Retroviruses written by and published by . This book was released on 1994 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retroviruses written by Reinhard Kurth and published by Caister Academic Press Limited. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
Download or read book Recent Advances In Human Retroviruses Principles Of Replication And Pathogenesis Advances In Retroviral Research written by Kuan-teh Jeang and published by World Scientific. This book was released on 2010-07-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are three major types of human retroviruses, namely HIV, HTLV, and endogenous human retroviruses. This book presents the latest findings on the replication of these human retroviruses. This book is unique in that there has been no comparable book that integrates the findings from the three known classes of human retroviruses. Other books have focused on one of the three classes of human retroviruses individually.An accomplished international team of contributing authors have combined their expertise to provide cutting-edge findings in this important field. The book will be a valuable reference for students, researchers and medical professionals.
Download or read book Human Retroviruses and Diseases They Cause written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retrovirus Biology and Human Disease written by Robert C. Gallo and published by CRC Press. This book was released on 1989-09-26 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book captures some of the essential developments, both historical and current, relating to the human retroviruses and the diseases they cause. It describes detailed molecular biology and epidemiology of human T-leukemia virus type 1 (HTLV-1).
