Download or read book Discovering the Human Connectome written by Olaf Sporns and published by MIT Press. This book was released on 2012-09-07 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.
Download or read book Connectome written by Sebastian Seung and published by HMH. This book was released on 2012-02-07 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Accessible, witty . . . an important new researcher, philosopher and popularizer of brain science . . . on par with cosmology’s Brian Greene and the late Carl Sagan” (The Plain Dealer). One of the Wall Street Journal’s 10 Best Nonfiction Books of the Year and a Publishers Weekly “Top Ten in Science” Title Every person is unique, but science has struggled to pinpoint where, precisely, that uniqueness resides. Our genome may determine our eye color and even aspects of our character. But our friendships, failures, and passions also shape who we are. The question is: How? Sebastian Seung is at the forefront of a revolution in neuroscience. He believes that our identity lies not in our genes, but in the connections between our brain cells—our particular wiring. Seung and a dedicated group of researchers are leading the effort to map these connections, neuron by neuron, synapse by synapse. It’s a monumental effort, but if they succeed, they will uncover the basis of personality, identity, intelligence, memory, and perhaps disorders such as autism and schizophrenia. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. “This is complicated stuff, and it is a testament to Dr. Seung’s remarkable clarity of exposition that the reader is swept along with his enthusiasm, as he moves from the basics of neuroscience out to the farthest regions of the hypothetical, sketching out a spectacularly illustrated giant map of the universe of man.” —TheNew York Times “An elegant primer on what’s known about how the brain is organized and how it grows, wires its neurons, perceives its environment, modifies or repairs itself, and stores information. Seung is a clear, lively writer who chooses vivid examples.” —TheWashington Post
Download or read book Micro Meso and Macro Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Download or read book Pattern Analysis of the Human Connectome written by Dewen Hu and published by Springer. This book was released on 2020-11-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent advances in pattern analysis of the human connectome. The human connectome, measured by magnetic resonance imaging at the macroscale, provides a comprehensive description of how brain regions are connected. Based on machine learning methods, multiviarate pattern analysis can directly decode psychological or cognitive states from brain connectivity patterns. Although there are a number of works with chapters on conventional human connectome encoding (brain-mapping), there are few resources on human connectome decoding (brain-reading). Focusing mainly on advances made over the past decade in the field of manifold learning, sparse coding, multi-task learning, and deep learning of the human connectome and applications, this book helps students and researchers gain an overall picture of pattern analysis of the human connectome. It also offers valuable insights for clinicians involved in the clinical diagnosis and treatment evaluation of neuropsychiatric disorders.
Download or read book Changing Connectomes written by Marcus Kaiser and published by MIT Press. This book was released on 2020-09-08 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages. The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development.
Download or read book Networks of the Brain written by Olaf Sporns and published by MIT Press. This book was released on 2010-10-01 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrative overview of network approaches to neuroscience, exploring the origins of brain complexity and the link between brain structure and function “This is where we should be looking for solutions to the great mysteries of life and the mind.” —American Scientist Over the last decade, the study of complex networks has expanded across diverse scientific fields. Increasingly, science is concerned with the structure, behavior, and evolution of complex systems ranging from cells to ecosystems. In Networks of the Brain, Olaf Sporns describes how the integrative nature of brain function can be illuminated from a complex network perspective. Highlighting the many emerging points of contact between neuroscience and network science, the book serves to introduce network theory to neuroscientists and neuroscience to those working on theoretical network models. Sporns emphasizes how networks connect levels of organization in the brain and how they link structure to function, offering an informal and nonmathematical treatment of the subject. Networks of the Brain provides a synthesis of the sciences of complex networks and the brain that will be an essential foundation for future research.
Download or read book Clinical Handbook of Psychiatry the Law written by Paul S. Appelbaum and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated for its Fourth Edition, this award-winning handbook gives mental health professionals authoritative guidance on how the law affects their clinical practice. Each chapter presents case examples of legal issues that arise in practice, clearly explains the governing legal rules, their rationale, and their clinical impact, and offers concrete action guides to navigating clinico-legal dilemmas. This edition addresses crucial recent developments including new federal rules protecting patients' privacy, regulations minimizing use of seclusion and restraint, liability risks associated with newer psychiatric medications, malpractice risks in forensic psychiatry, and new structured assessment tools for violence risk, suicidality, and decisional capacity.
Download or read book Psychobiology of Behaviour written by Kostas N. Fountoulakis and published by Springer. This book was released on 2019-07-26 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a comprehensive reference on the neurobiological understanding of behaviour, how behaviour is regulated by the brain, and how such behaviours in turn influence the brain. The work offers an introduction to neural systems and genetics/epigenetics, followed by detailed study of a wide range of behaviours – temperament and personality, instincts and drives, memory and cognitive function, sex and sexual differentiation, ethology and evolutionary biology, aging, drug abuse and other problematic behaviors, psychophysiology and ultimately the links to biological psychiatry and psychopharmacology. Research findings on the neural basis of social behaviour are integrated across different levels of analysis, from molecular neurobiology and neural systems/behavioural neuroscience to fMRI imaging data on human social behaviour. The content covers research on both normal and abnormal behaviours, as well as developmental aspects. The target audience includes psychiatrists, neurologists, nurses, psychologists and all researchers and advanced students in behavioural, social and developmental neuroscience, as well as clinical neuroscientists.
Download or read book Connectomic Deep Brain Stimulation written by Andreas Horn and published by Academic Press. This book was released on 2021-09-10 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. - Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery - Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) - Presents references (key articles, books and protocols) for additional detailed study - Provides data analysis boxes in each chapter to help with data interpretation
Download or read book Evolution of the Human Brain From Matter to Mind written by and published by Academic Press. This book was released on 2019-11-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution of the Human Brain: From Matter to Mind, Volume 250 in the Progress in Brain Research, series documents the latest developments and insights about the origin and evolution of the human brain and mind. Specific sections in this new release include Evolution and development of the human cerebral cortex, Functional connectivity of the human cerebral cortex, Lateralization of the human cerebral cortex, Life history strategies and the human cerebral cortex, Evolution of the modern human brain, On the nature and evolution of the human mind, Origin and evolution of human cognition, Origin and evolution of human consciousness, and more. - Presents insights on molecular and cellular mechanisms of human brain evolution - Provides a better understanding of the origin and evolution of the human mind - Includes information of the neural organization and functional connectivity of the cerebral cortex
Download or read book Fundamentals of Brain Network Analysis written by Alex Fornito and published by Academic Press. This book was released on 2016-03-04 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Download or read book Wired for Culture Origins of the Human Social Mind written by Mark Pagel and published by W. W. Norton & Company. This book was released on 2012-02-07 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating, far-reaching study of how our species' innate capacity for culture altered the course of our social and evolutionary history. A unique trait of the human species is that our personalities, lifestyles, and worldviews are shaped by an accident of birth—namely, the culture into which we are born. It is our cultures and not our genes that determine which foods we eat, which languages we speak, which people we love and marry, and which people we kill in war. But how did our species develop a mind that is hardwired for culture—and why? Evolutionary biologist Mark Pagel tracks this intriguing question through the last 80,000 years of human evolution, revealing how an innate propensity to contribute and conform to the culture of our birth not only enabled human survival and progress in the past but also continues to influence our behavior today. Shedding light on our species’ defining attributes—from art, morality, and altruism to self-interest, deception, and prejudice—Wired for Culture offers surprising new insights into what it means to be human.
Download or read book Discovering the Human Connectome written by Olaf Sporns and published by MIT Press. This book was released on 2012-08-31 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.
Download or read book Brain Architecture Understanding the Basic Plan written by and Director NIBS Neuroscience Program University of Southern California Larry W. Swanson Milo Don and Lucille Appleman Professor of Biological Sciences and published by Oxford University Press, USA. This book was released on 2002-10-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depending on your point of view the brain is an organ, a machine, a biological computer, or simply the most important component of the nervous system. How does it work as a whole? What are its major parts and how are they interconnected to generate thinking, feelings, and behavior? This book surveys 2,500 years of scientific thinking about these profoundly important questions from the perspective of fundamental architectural principles, and then proposes a new model for the basic plan of neural systems organization based on an explosion of structural data emerging from the neuroanatomy revolution of the 1970's. The importance of a balance between theoretical and experimental morphology is stressed throughout the book. Great advances in understanding the brain's basic plan have come especially from two traditional lines of biological thought-- evolution and embryology, because each begins with the simple and progresses to the more complex. Understanding the organization of brain circuits, which contain thousands of links or pathways, is much more difficult. It is argued here that a four-system network model can explain the structure-function organization of the brain. Possible relationships between neural networks and gene networks revealed by the human genome project are explored in the final chapter. The book is written in clear and sparkling prose, and it is profusely illustrated. It is designed to be read by anyone with an interest in the basic organization of the brain, from neuroscience to philosophy to computer science to molecular biology. It is suitable for use in neuroscience core courses because it presents basic principles of the structure of the nervous system in a systematic way.
Download or read book Brain and Human Body Modeling 2020 written by Sergey N. Makarov and published by Springer Nature. This book was released on 2021 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
Download or read book Ay s Neuroanatomy of C Elegans for Computation written by Theodore B. Achacoso and published by CRC Press. This book was released on 1991-11-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: AY's Neuroanatomy of C. elegans for Computation provides the neural circuitry database of the nematode Caenorhabditis elegans, both in printed form and in ASCII files on 5.25-inch diskettes (for use on IBM® and compatible personal computers, Macintosh® computers, and higher level machines). Tables of connections among neuron classes, synapses among individual neurons, gap junctions among neurons, worm cells and their embryonic origin, and synthetically derived neuromuscular connections are presented together with the references from which the data were compiled and edited. Sample data files and source codes of FORTRAN and BASIC programs are provided to illustrate the use of mathematical tools for any researcher or student interested in examining a natural neural network and discovering what makes it tick.
Download or read book Atlas of Human Brain Connections written by Marco Catani and published by Oxford University Press, USA. This book was released on 2012-06-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
