Download or read book The Guinea Pig Model written by Viviana Parreño and published by CRC Press. This book was released on 2023-04-10 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US. Key Features Reviews combined vaccines used for cattle Summarizes animal models used for vaccine testing Focuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus Provides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Download or read book A Guinea Pig Model for Low level Lead Toxicity During Gestation written by Evelyn Marie Sierra and published by . This book was released on 1991 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development of a Guinea Pig Model of Allergic Respiratory Disease written by Charles Parnell Cox and published by . This book was released on 1978 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Guinea Pig Placenta written by P. Kaufmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: The placenta of the guinea-pig has assumed exceptional importance among the discoidal hemochorial placentae since the end of the sixties. Up to that date, numerous studies had been published on the functional analysis of the human placenta. One shortcom ing common to all these studies, however, was the fact, that the human placenta was not absolutely suitable for morphological research, owing to fIxation difficulties, and for experimental investigations virtually unsuitable. Since other hemochorial villous placentae, like that of the anthropoid apes (primates) were practically unobtainable, a possible alternative was sought among the I;tcunal placentae. The numerous studies on the guinea-pig placenta undertaken at the turn of the century favoured the choice of this organ as it also belonged to the discoidal hemochorial type, like that of man. The fact that its structure was not villous but lacunal and therefore showed a different cir culation seemed even advantageous in this case. The lacunal system facilitates differen tiation in morphologically distinct areas, which allow independent functional analysis. The morphological and histochemical studies made during the past decade by Enders (1965), Vollrath (1965), Miiller and Fischer (1968), Kaufmann (1969a), Davidoff and Schiebler (1970a, b), King and Enders (1970b, 1971), Davidoff and Gospodinoff (1971), Davidoff (1973), Kaufmann (1974) have led to the discovery of a large amount of new information on this organ, thus rendering it one of the most precisely examined placentae so far.

Download or read book Development of a novel guinea pig model of allergic airways disease written by María Cristina Seminario and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development of a Guinea Pig Model for Low Dose Chronic Exposure to Organophosphorus Nerve Agents written by and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An animal dosing model and related maximum tolerated dose (MTD) were developed for repeated exposures in guinea pigs to three organophosphorus chemical warfare nerve agents (CWNA). Male animals were injected subcutaneously with sarin (GB), soman (GD) or VX once a day (Monday through Friday) for 2-, 4-, or 13-weeks. An initial 13-week study for each CWNA employed doses of vehicle (normal saline), 0.2, 0.4, 0.6, and 0.8 x the previously established acute LD50. A 2-week and 4-week exposure were also performed for each agent at doses less than the 13-week MTD to verify lack of toxicity. Animals dosed daily for 13 weeks with 0.4 x LD50 of GB or GD or with 0.2 x LD50 of VX did not display signs of acute cholinergic toxicity. In animals dosed daily for either 2- or 4-weeks, the MTDs were 0.4 x the acute LD50 for all 3 CWNA. There were no differences among these groups and their respective vehicle controls for weight gains, body temperature, complete blood cell counts, blood chemistries, nor by histopathology. At the MTD in all groups, red blood cell cholinesterase activity one hour alter the last exposure was inhibited up to 90% compared with controls.

Download or read book A Guinea Pig s History of Biology written by Jim Endersby and published by Harvard University Press. This book was released on 2007 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Endless forms most beautiful and most wonderful have been, and are being, evolved," Darwin famously concluded The Origin of Species, and for confirmation we look to...the guinea pig? How this curious creature and others as humble (and as fast-breeding) have helped unlock the mystery of inheritance is the unlikely story Jim Endersby tells in this book. Biology today promises everything from better foods or cures for common diseases to the alarming prospect of redesigning life itself. Looking at the organisms that have made all this possible gives us a new way of understanding how we got here--and perhaps of thinking about where we're going. Instead of a history of which great scientists had which great ideas, this story of passionflowers and hawkweeds, of zebra fish and viruses, offers a bird's (or rodent's) eye view of the work that makes science possible. Mixing the celebrities of genetics, like the fruit fly, with forgotten players such as the evening primrose, the book follows the unfolding history of biological inheritance from Aristotle's search for the "universal, absolute truth of fishiness" to the apparently absurd speculations of eighteenth-century natural philosophers to the spectacular findings of our day--which may prove to be the absurdities of tomorrow. The result is a quirky, enlightening, and thoroughly engaging perspective on the history of heredity and genetics, tracing the slow, uncertain path--complete with entertaining diversions and dead ends--that led us from the ancient world's understanding of inheritance to modern genetics.

Download or read book Animal Biotechnology written by Ashish S. Verma and published by Academic Press. This book was released on 2013-11-04 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. - Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases - Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering

Download or read book Nutrient Requirements of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Download or read book Electrically Evoked Auditory Steady state Responses in a Guinea Pig Model written by Fuh-Cherng Jeng and published by . This book was released on 2006 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Guinea Pig Scientists written by Leslie Dendy and published by Macmillan. This book was released on 2005-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stories of ten men and women, from the 1770s to the present, who devoted their lives, and sometimes risked them, to answer some of the big questions in science and medicine.

Download or read book The Biology of the Guinea Pig written by Joseph E. Wagner and published by Academic Press. This book was released on 2014-04-25 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.317 pages

Download or read book Buruli Ulcer written by Gerd Pluschke and published by Springer. This book was released on 2019-04-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Download or read book Humoral Regulation of the Immune Spectrum in a Guinea Pig Model of Tuberculosis written by Margaret Scot Smith and published by . This book was released on 1993 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Download or read book The Guinea Pig as a Model for Isoniazid Induced Reactions written by Gregory B. Heisey and published by . This book was released on 1979 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Guinea pig Model for Separate and Mixed Infections of the Female Genital Tract with Chlamydia and Herpes Simplex Virus written by Sahira Abdul-Hussein Khalaf and published by . This book was released on 1987 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: