Download or read book The General Stress Responsive Sigma Factor B and Its Role in Intracellular Parasitism of Listeria Monocytogenes written by Hee-Sun Kim and published by . This book was released on 2004 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book RNA Polymerase Sigma Factor B written by Adriana de Oliveira Ferreira and published by . This book was released on 2002 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Alternative Sigma Factor B and Stress Response in Listeria Monocytogenes written by David Sue and published by . This book was released on 2004 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stress Response Alternative Sigma Factor Sigma B and Virulence of Listeria Monocytogenes written by Celine Andree Nadon and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 2003 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Contributions of Sigma B and PrFa to Stress Response and Virulence Gene Expression in Listeria Monocytogenes written by Mark Joseph Kazmierczak and published by . This book was released on 2005 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Role of the Alternative Sigma Factor Sigma B in Stress Response and Regulation of Virulence in Listeria Monocytogenes written by Lynne A. Becker and published by . This book was released on 2002 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Role of the Alternative Sigma Factor superscript B in Osmotic Response and Regulation of Stress Response in Listeria Monocytogenes written by Mehmet Sevket Cetin and published by . This book was released on 2003 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Alternative Sigma Factors of Listeria Monocytogenes written by Sana Mujahid and published by . This book was released on 2013 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: The foodborne pathogen Listeria monocytogenes is ubiquitous in the environment and can cause a life-threatening invasive infection in humans. L. monocytogenes has the ability to survive a wide range of environmental and physiological stress conditions through complex stress response and virulence mechanisms. Among the key mechanisms L. monocytogenes employs to respond to changing conditions, including those encountered during growth on food and in the infection process, is the regulation of gene, protein, and non-coding RNA (ncRNA) expression through the regulatory network of the alternative sigma factors, [sigma]B, [sigma]C, [sigma]H, and [sigma]L. In these studies we (i) explored [sigma]B-dependent regulation of the ncRNA SbrE, and (ii) determined [sigma]B, [sigma]C, [sigma]H, and [sigma]L regulons at the protein level using a quantitative proteomics approach. We demonstrated [sigma]B-dependent transcription of SbrE and identified putative targets of SbrE at the transcriptomic and proteomic level. We also found increased transcript levels of SbrE in stationary phase and after exposure of L. monocytogenes to oxidative stress. Our proteomic analysis of L. monocytogenes parent strain 10403S and a [DELTA]sigB mutant combined with a meta-analysis of published transcriptomic studies identified 149 genes and proteins as positively regulated by [sigma]B at either or both the transcript and protein level, and suggested contributions of [sigma]B to gene expression through direct regulation of gene transcription and through indirect mechanisms, including regulation of ncRNA. Finally, our comparison of the protein expression profiles of parent strain 10403S and a quadruple mutant [DELTA]sigBCHL, and comparisons of [DELTA]sigBCHL with triple mutants, [DELTA]sigBCH, [DELTA]sigBCL, and [DELTA]sigBHL, characterized the independent regulons of [sigma]L, [sigma]H, and [sigma]C at the protein level, as well as co-regulation and protein expression in the absence of all four alternative [sigma] factors. Co-regulated proteins identified included MptA, which has a potential role in regulation of PrfA, a transcriptional activator of L. monocytogenes virulence genes. These studies identify and characterize components of the complex regulatory network of L. monocytogenes alternative [sigma] factors and illustrate co-regulation of gene expression by multiple alternative [sigma] factors, which contributes to our understanding of the alternative [sigma] factor dependent stress response and virulence abilities of L. monocytogenes.

Download or read book Foodborne Microbial Pathogens written by Arun K. Bhunia and published by Springer. This book was released on 2018-05-21 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book primarily covers the general description of foodborne pathogens and their mechanisms of pathogenesis, control and prevention, and detection strategies, with easy-to-comprehend illustrations. The book is an essential resource for food microbiology graduate or undergraduate students, microbiology professionals, and academicians involved in food microbiology, food safety, and food defense-related research or teaching. This new edition covers the significant progress that has been made since 2008 in understanding the pathogenic mechanism of some common foodborne pathogens, and the host-pathogen interaction. Foodborne and food-associated zoonotic pathogens, responsible for high rates of mortality and morbidity, are discussed in detail. Chapters on foodborne viruses, parasites, molds and mycotoxins, and fish and shellfish are expanded. Additionally, chapters on opportunistic and emerging foodborne pathogens including Nipah virus, Ebola virus, Aeromonas hydrophila, Brucella abortus, Clostridium difficile, Cronobacter sakazakii, and Plesiomonas shigelloides have been added. The second edition contains more line drawings, color photographs, and hand-drawn illustrations.

Download or read book Regulation of Transcription Factor Sigma B Activity in the Foodborne Pathogen Listeria Monocytogenes written by Soraya Chaturongakul and published by . This book was released on 2006 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The New Microbiology written by Pascale Cossart and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology has undergone radical changes over the past few decades, ushering in an exciting new era in science. In The New Microbiology, Pascale Cossart tells a splendid story about the revolution in microbiology, especially in bacteriology. This story has wide-ranging implications for human health and medicine, agriculture, environmental science, and our understanding of evolution. The revolution results from the powerful tools of molecular and cellular biology, genomics, and bioinformatics, which have yielded amazing discoveries, from entire genome sequences to video of bacteria invading host cells. This book is for both scientists and especially nonscientists who would like to learn more about the extraordinary world of bacteria. Dr. Cossart's overview of the field of microbiology research, from infectious disease history to the ongoing scientific revolution resulting from CRISPR technologies, is presented in four parts. New concepts in microbiology introduces the world of bacteria and some recent discoveries about how they live, such as the role of regulatory RNAs including riboswitches, the CRISPR defense system, and resistance to antibiotics. Sociomicrobiology: the social lives of bacteria helps us see the new paradigm by which scientists view bacteria as highly social creatures that communicate in many ways, for example in the assemblies that reside in our intestine or in the environment. The biology of infections reviews some of history's worst epidemics and describes current and emerging infectious diseases, the organisms that cause them, and how they produce an infection. Bacteria as tools introduces us to molecules derived from microbes that scientists have harnessed in the service of research and medicine, including the CRISPR/Cas9 genome-editing technology. The New Microbiology takes us on a journey through a remarkable revolution in science that is occurring here and now.

Download or read book Gram positive Pathogens written by Vincent A. Fischetti and published by . This book was released on 2000 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the only single volume to deal with all aspects of gram–positive pathogens. It addresses the mechanisms of gram–positive bacterial pathogenicity, including the current knowledge on gram–positive structure and mechanisms of antibiotic resistance. Emphasizing streptococci, staphylococci, listeria, and spore–forming pathogens, Gram–Positive Pathogens includes chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically in an attempt to understand the strategies used by these bacteria to cause human disease.

Download or read book Applied and Environmental Microbiology written by and published by . This book was released on 2007 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Foodborne Pathogens written by Joshua B. Gurtler and published by Springer. This book was released on 2017-06-14 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne illnesses continue to be a major public health concern. All members of a particular bacterial genera (e.g., Salmonella, Campylobacter) or species (e.g., Listeria monocytogenes, Cronobacter sakazakii) are often treated by public health and regulatory agencies as being equally pathogenic; however, this is not necessarily true and is an overly conservative approach to ensuring the safety of foods. Even within species, virulence factors vary to the point that some isolates may be highly virulent, whereas others may rarely, if ever, cause disease in humans. Hence, many food safety scientists have concluded that a more appropriate characterization of bacterial isolates for public health purposes could be by virotyping, i.e., typing food-associated bacteria on the basis of their virulence factors. The book is divided into two sections. Section I, “Foodborne Pathogens and Virulence Factors,” hones in on specific virulence factors of foodborne pathogens and the role they play in regulatory requirements, recalls, and foodborne illness. The oft-held paradigm that all pathogenic strains are equally virulent is untrue. Thus, we will examine variability in virulence between strains such as Listeria, Salmonella, Campylobacter, Cronobacter, etc. This section also examines known factors capable of inducing greater virulence in foodborne pathogens. Section II, “Foodborne Pathogens, Host Susceptibility, and Infectious Dose” , covers the ability of a pathogen to invade a human host based on numerous extraneous factors relative to the host and the environment. Some of these factors include host age, immune status, genetic makeup, infectious dose, food composition and probiotics. Readers of this book will come away with a better understanding of foodborne bacterial pathogen virulence factors and pathogenicity, and host factors that predict the severity of disease in humans.

Download or read book The Prokaryotes written by Stanley Falkow and published by Springer Science & Business Media. This book was released on 2006-10-10 with total page 965 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised Third Edition of The Prokaryotes, acclaimed as a classic reference in the field, offers new and updated articles by experts from around the world on taxa of relevance to medicine, ecology and industry. Entries combine phylogenetic and systematic data with insights into genetics, physiology and application. Existing entries have been revised to incorporate rapid progress and technological innovation. The new edition improves on the lucid presentation, logical layout and abundance of illustrations that readers rely on, adding color illustration throughout. Expanded to seven volumes in its print form, the new edition adds a new, searchable online version.

Download or read book Actin based Motility written by Marie-France Carlier and published by Springer Science & Business Media. This book was released on 2010-09-23 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.

Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.