Download or read book The Function of Pathological States in Evolution written by Morley Charles Roberts and published by . This book was released on 1919 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A History of Pathology written by Esmond Ray Long and published by . This book was released on 1965 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Spinal Evolution written by Ella Been and published by Springer. This book was released on 2019-08-07 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebral spine is a key element of the human anatomy. Its main role is to protect the spinal cord and the main blood vessels. The axial skeleton, with its muscles and joints, provides stability for the attachment of the head, tail and limbs and, at the same time, enables the mobility required for breathing and for locomotion. Despite its great importance, the vertebral spine is often over looked by researchers because: a) vertebrae are fragile in nature, which makes their fossilization a rare event; b) they are metameric (seriated and repeated elements) that make their anatomical determination and, thus, their subsequent study difficult; and c) the plethora of bones and joints involved in every movement or function of the axial skeleton makes the reconstruction of posture, breathing mechanics and locomotion extremely difficult. It is well established that the spine has changed dramatically during human evolution. Spinal curvatures, spinal load transmission, and thoracic shape of bipedal humans are derived among hominoids. Yet, there are many debates as to how and when these changes occurred and to their phylogenetic, functional, and pathological implications. In recent years, renewed interest arose in the axial skeleton. New and exciting finds, mostly from Europe and Africa, as well as new methods for reconstructing the spine, have been introduced to the research community. New methodologies such as Finite Element Analysis, trabecular bone analysis, Geometric Morphometric analysis, and gait analysis have been applied to the spines of primates and humans. These provide a new and refreshing look into the evolution of the spine. Advanced biomechanical research regarding posture, range of motion, stability, and attenuation of the human spine has interesting evolutionary implications. Until now, no book that summarizes the updated research and knowledge regarding spinal evolution in hominoids has been available. The present book explores both these new methodologies and new data, including recent fossil, morphological, biomechanical, and theoretical advances regarding vertebral column evolution. In order to cover all of that data, we divide the book into four parts: 1) the spine of hominoids; 2) the vertebral spine of extinct hominins; 3) ontogeny, biomechanics and pathology of the human spine; and 4) new methodologies of spinal research. These parts complement each other and provide a wide and comprehensive examination of spinal evolution.
Download or read book The Role of Telehealth in an Evolving Health Care Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2012-12-20 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996, the Institute of Medicine (IOM) released its report Telemedicine: A Guide to Assessing Telecommunications for Health Care. In that report, the IOM Committee on Evaluating Clinical Applications of Telemedicine found telemedicine is similar in most respects to other technologies for which better evidence of effectiveness is also being demanded. Telemedicine, however, has some special characteristics-shared with information technologies generally-that warrant particular notice from evaluators and decision makers. Since that time, attention to telehealth has continued to grow in both the public and private sectors. Peer-reviewed journals and professional societies are devoted to telehealth, the federal government provides grant funding to promote the use of telehealth, and the private technology industry continues to develop new applications for telehealth. However, barriers remain to the use of telehealth modalities, including issues related to reimbursement, licensure, workforce, and costs. Also, some areas of telehealth have developed a stronger evidence base than others. The Health Resources and Service Administration (HRSA) sponsored the IOM in holding a workshop in Washington, DC, on August 8-9 2012, to examine how the use of telehealth technology can fit into the U.S. health care system. HRSA asked the IOM to focus on the potential for telehealth to serve geographically isolated individuals and extend the reach of scarce resources while also emphasizing the quality and value in the delivery of health care services. This workshop summary discusses the evolution of telehealth since 1996, including the increasing role of the private sector, policies that have promoted or delayed the use of telehealth, and consumer acceptance of telehealth. The Role of Telehealth in an Evolving Health Care Environment: Workshop Summary discusses the current evidence base for telehealth, including available data and gaps in data; discuss how technological developments, including mobile telehealth, electronic intensive care units, remote monitoring, social networking, and wearable devices, in conjunction with the push for electronic health records, is changing the delivery of health care in rural and urban environments. This report also summarizes actions that the U.S. Department of Health and Human Services (HHS) can undertake to further the use of telehealth to improve health care outcomes while controlling costs in the current health care environment.
Download or read book Principles of Evolutionary Medicine written by Peter D. Gluckman and published by Oxford University Press. This book was released on 2016 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.
Download or read book Evolution written by Brian Charlesworth and published by Oxford University Press. This book was released on 2017 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is about the central role of evolution in shaping the nature and diversity of the living world. It describes the processes of natural selection, how adaptations arise, and how new species form, as well as summarizing the evidence for evolution
Download or read book Understanding Human Anatomy and Pathology written by Rui Diogo and published by CRC Press. This book was released on 2018-09-03 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Human Anatomy and Pathology: An Evolutionary and Developmental Guide for Medical Students provides medical students with a much easier and more comprehensive way to learn and understand human gross anatomy by combining state-of-the-art knowledge about human anatomy, evolution, development, and pathology in one book. The book adds evolutionary, pathological, and developmental information in a way that reduces the difficulty and total time spent learning gross anatomy by making learning more logical and systematic. It also synthesizes data that would normally be available for students only by consulting several books at a time. Anatomical illustrations are carefully selected to follow the style of those seen in human anatomical atlases but are simpler in their overall configuration, making them easier to understand without overwhelming students with visual information. The book’s organization is also more versatile than most human anatomy texts so that students can refer to different sections according to their own learning styles. Because it is relatively short in length and easily transportable, students can take this invaluable book anywhere and use it to understand most of the structures they need to learn for any gross anatomy course.
Download or read book Microbial Evolution and Co Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Download or read book Ortner s Identification of Pathological Conditions in Human Skeletal Remains written by Jane Buikstra and published by Academic Press. This book was released on 2019-01-29 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ortner's Identification of Pathological Conditions in Human Skeletal Remains, Third Edition, provides an integrated and comprehensive treatment of the pathological conditions that affect the human skeleton. As ancient skeletal remains can reveal a treasure trove of information to the modern orthopedist, pathologist, forensic anthropologist, and radiologist, this book presents a timely resource. Beautifully illustrated with over 1,100 photographs and drawings, it provides an essential text and material on bone pathology, thus helping improve the diagnostic ability of those interested in human dry bone pathology. Presents a comprehensive review of the skeletal diseases encountered in archaeological human remains Includes more than 1100 photographs and line drawings illustrating skeletal diseases, including both microscopic and gross features Based on extensive research on skeletal paleopathology in many countries Reviews important theoretical issues on how to interpret evidence of skeletal disease in archaeological human populations
Download or read book Systematics and Evolution written by David J. McLaughlin and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycology, the study of fungi, originated as a subdiscipline of botany and was a des criptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgetf, Kniep and Lindegren are all associated with this early period of fungal genet ics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for biochemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cerevisiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.
Download or read book The Evolution of the Human Head written by Daniel Lieberman and published by Harvard University Press. This book was released on 2011-01-03 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exhaustively researched and years in the making, this innovative book documents how the many components of the head function, how they evolved since we diverged from the apes, and how they interact in diverse ways both functionally and developmentally, causing them to be highly integrated. This integration not only permits the head's many units to accommodate each other as they grow and work, but also facilitates evolutionary change. Lieberman shows how, when, and why the major transformations evident in the evolution of the human head occurred. The special way the head is integrated, Lieberman argues, made it possible for a few developmental shifts to have had widespread effects on craniofacial growth, yet still permit the head to function exquisitely. --
Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. - Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease - Explains the practice of "molecular medicine and the translational aspects of molecular pathology - Teaches from the perspective of "integrative systems biology - Enhanced digital version included with purchase
Download or read book Cancer Evolution written by Charles Swanton and published by Perspectives Cshl. This book was released on 2017 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.
Download or read book Hemoglobin written by Richard Earl Dickerson and published by Benjamin-Cummings Publishing Company. This book was released on 1983 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evolutionary Psychopathology written by Marco Del Giudice and published by Oxford University Press. This book was released on 2018-07-06 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental disorders arise from neural and psychological mechanisms that have been built and shaped by natural selection across our evolutionary history. Looking at psychopathology through the lens of evolution is the only way to understand the deeper nature of mental disorders and turn a mass of behavioral, genetic, and neurobiological findings into a coherent, theoretically grounded discipline. The rise of evolutionary psychopathology is part of an exciting scientific movement in psychology and medicine -- a movement that is fundamentally transforming the way we think about health and disease. Evolutionary Psychopathology takes steps toward a unified approach to psychopathology, using the concepts of life history theory -- a biological account of how individual differences in development, physiology and behavior arise from tradeoffs in survival and reproduction -- to build an integrative framework for mental disorders. This book reviews existing evolutionary models of specific conditions and connects them in a broader perspective, with the goal of explaining the large-scale patterns of risk and comorbidity that characterize psychopathology. Using the life history framework allows for a seamless integration of mental disorders with normative individual differences in personality and cognition, and offers new conceptual tools for the analysis of developmental, genetic, and neurobiological data. The concepts presented in Evolutionary Psychopathology are used to derive a new taxonomy of mental disorders, the Fast-Slow-Defense (FSD) model. The FSD model is the first classification system explicitly based on evolutionary concepts, a biologically grounded alternative to transdiagnostic models. The book reviews a wide range of common mental disorders, discusses their classification in the FSD model, and identifies functional subtypes within existing diagnostic categories.
Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Download or read book Guiding the Surgeon s Hand written by Juan Rosai and published by American Registry of Pathology. This book was released on 1997 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
