Download or read book The Four Villains of Clinical Trial Agreement Delays and How to Defeat Them written by Débora S. Araujo and published by WestBow Press. This book was released on 2018-04-09 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fictional superheroes are often charged with the task of saving the world from villains such as the Joker, Lex Luthor, Doctor Doom, and the Green Goblin. But superheroes cannot be effective if they only take out one of their villains and let the others roam free. In the same way, the pharmaceutical industry cannot effectively tackle the issue of delays in the execution of clinical trial agreements (CTAs) that leave patients lives hanging in the balance by only addressing one or two of the villains contributing to this broad challenge. Dbora Araujo relies on seasoned experience in the pharmaceutical industry that includes consulting for Fortune 500 companies and driving practical change regarding the business aspects of clinical trials to share a comprehensive exploration of the four villains who contribute to CTA negotiation delays and provide practical ways to address each of them. While encouraging positive change that patients desperately need, Araujo examines the negative impacts of ineffective site-budget negotiations, poor outsourced negotiations, a lack of industry adoption and innovation, and other issues affecting CTA negotiations. Included are several checklists, a common language evaluation and reconciliation initiative, and general CTA country requirements. In this comprehensive study, a pharmaceutical professional creatively examines how to address the four villains that cause frustrating delays in the execution of clinical trial agreements.
Download or read book Microbiology of Wounds written by Steven Percival and published by CRC Press. This book was released on 2010-04-26 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is not the presence of microorganisms, but their interaction with patients that determines their influence on wound healing. Documenting this critical but often ignored aspect of the treatment process, Microbiology of Wounds discusses the microbiology and biology of human wounds in relation to infection and non-healing. Gain the Necessary Scient
Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Download or read book Trade and Environment written by Adil Najam and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reconciliation After Violent Conflict written by David Bloomfield and published by . This book was released on 2003 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: How does a newly democratized nation constructively address the past to move from a divided history to a shared future? How do people rebuild coexistence after violence? The International IDEA Handbook on Reconciliation after Violent Conflict presents a range of tools that can be, and have been, employed in the design and implementation of reconciliation processes. Most of them draw on the experience of people grappling with the problems of past violence and injustice. There is no "right answer" to the challenge of reconciliation, and so the Handbook prescribes no single approach. Instead, it presents the options and methods, with their strengths and weaknesses evaluated, so that practitioners and policy-makers can adopt or adapt them, as best suits each specific context. Also available in a French language version.
Download or read book The Uninhabitable Earth written by David Wallace-Wells and published by Tim Duggan Books. This book was released on 2019-02-19 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 NEW YORK TIMES BESTSELLER • “The Uninhabitable Earth hits you like a comet, with an overflow of insanely lyrical prose about our pending Armageddon.”—Andrew Solomon, author of The Noonday Demon NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New Yorker • The New York Times Book Review • Time • NPR • The Economist • The Paris Review • Toronto Star • GQ • The Times Literary Supplement • The New York Public Library • Kirkus Reviews It is worse, much worse, than you think. If your anxiety about global warming is dominated by fears of sea-level rise, you are barely scratching the surface of what terrors are possible—food shortages, refugee emergencies, climate wars and economic devastation. An “epoch-defining book” (The Guardian) and “this generation’s Silent Spring” (The Washington Post), The Uninhabitable Earth is both a travelogue of the near future and a meditation on how that future will look to those living through it—the ways that warming promises to transform global politics, the meaning of technology and nature in the modern world, the sustainability of capitalism and the trajectory of human progress. The Uninhabitable Earth is also an impassioned call to action. For just as the world was brought to the brink of catastrophe within the span of a lifetime, the responsibility to avoid it now belongs to a single generation—today’s. LONGLISTED FOR THE PEN/E.O. WILSON LITERARY SCIENCE WRITING AWARD “The Uninhabitable Earth is the most terrifying book I have ever read. Its subject is climate change, and its method is scientific, but its mode is Old Testament. The book is a meticulously documented, white-knuckled tour through the cascading catastrophes that will soon engulf our warming planet.”—Farhad Manjoo, The New York Times “Riveting. . . . Some readers will find Mr. Wallace-Wells’s outline of possible futures alarmist. He is indeed alarmed. You should be, too.”—The Economist “Potent and evocative. . . . Wallace-Wells has resolved to offer something other than the standard narrative of climate change. . . . He avoids the ‘eerily banal language of climatology’ in favor of lush, rolling prose.”—Jennifer Szalai, The New York Times “The book has potential to be this generation’s Silent Spring.”—The Washington Post “The Uninhabitable Earth, which has become a best seller, taps into the underlying emotion of the day: fear. . . . I encourage people to read this book.”—Alan Weisman, The New York Review of Books
Download or read book Change Forces written by Michael Fullan and published by Routledge. This book was released on 2012-11-12 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the processes of educational change is said to be the missing ingredient in attempts to bring about educational innovation and reform. Whether these efforts involve grass roots innovation or large-scale societal reform, failure to understand and act on existing knowledge of the change process has accounted for the widespread lack of success in making educational improvements. This volume analyzes what is known about successful or productive change processes, and identifies corresponding action strategies at the individual, school, local and state levels. Included in this book is a major treatment of the topic of the 'ethics of planned change', a neglected topic in recent literature, especially since strategies for intervening in the change process are receiving more attention. This book is intended to be used by teachers in training and in service, teacher trainers, educational researchers, education historians and administrators.
Download or read book Trust in Numbers written by Theodore M. Porter and published by Princeton University Press. This book was released on 2020-08-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: A foundational work on historical and social studies of quantification What accounts for the prestige of quantitative methods? The usual answer is that quantification is desirable in social investigation as a result of its successes in science. Trust in Numbers questions whether such success in the study of stars, molecules, or cells should be an attractive model for research on human societies, and examines why the natural sciences are highly quantitative in the first place. Theodore Porter argues that a better understanding of the attractions of quantification in business, government, and social research brings a fresh perspective to its role in psychology, physics, and medicine. Quantitative rigor is not inherent in science but arises from political and social pressures, and objectivity derives its impetus from cultural contexts. In a new preface, the author sheds light on the current infatuation with quantitative methods, particularly at the intersection of science and bureaucracy.
Download or read book Archaeology Anthropology and Interstellar Communication written by National Aeronautics Administration and published by CreateSpace. This book was released on 2014-09-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a field that has been dominated by astronomers, physicists, engineers, and computer scientists, the contributors to this collection raise questions that may have been overlooked by physical scientists about the ease of establishing meaningful communication with an extraterrestrial intelligence. These scholars are grappling with some of the enormous challenges that will face humanity if an information-rich signal emanating from another world is detected. By drawing on issues at the core of contemporary archaeology and anthropology, we can be much better prepared for contact with an extraterrestrial civilization, should that day ever come.
Download or read book Guide to U S Elections written by Deborah Kalb and published by CQ Press. This book was released on 2015-12-24 with total page 5685 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CQ Press Guide to U.S. Elections is a comprehensive, two-volume reference providing information on the U.S. electoral process, in-depth analysis on specific political eras and issues, and everything in between. Thoroughly revised and infused with new data, analysis, and discussion of issues relating to elections through 2014, the Guide will include chapters on: Analysis of the campaigns for presidency, from the primaries through the general election Data on the candidates, winners/losers, and election returns Details on congressional and gubernatorial contests supplemented with vast historical data. Key Features include: Tables, boxes and figures interspersed throughout each chapter Data on campaigns, election methods, and results Complete lists of House and Senate leaders Links to election-related websites A guide to party abbreviations
Download or read book International Standard Classification of Occupations written by International Labour Office and published by International Labor Office. This book was released on 2012 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Standard Classification of Occupations 2008 (ISCO-08) is a four-level hierarchically structured classification that covers all jobs in the world. Developed with the benefit of accumulated national and international experience as well as the help of experts from many countries and agencies, ISCO-08 is fully supported by the international community as an accepted standard for international labour statistics. ISCO-08 classifies jobs into 436 unit groups. These unit groups are aggregated into 130 minor groups, 43 sub-major groups and 10 major groups, based on their similarity in terms of the skill level and skill specialisation required for the jobs. This allows the production of relatively detailed internationally comparable data as well as summary information for only 10 groups at the highest level of aggregation. Each group in the classification is designated by a title and code number and is associated with a definition that specifies the scope of the group. The classification is divided into two volumes: Volume I presents the structure and definitions of all groups in ISCO-08 and their correspondence with ISCO-88, which it supersedes, while Volume II provides an updated and expanded index of occupational titles and associated ISCO-08 and ISCO-88 codes.
Download or read book The Conservative Nanny State written by Dean Baker and published by Lulu.com. This book was released on 2006 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his new book, economist Dean Baker debunks the myth that conservatives favor the market over government intervention. In fact, conservatives rely on a range of "nanny state" policies that ensure the rich get richer while leaving most Americans worse off. It's time for the rules to change. Sound economic policy should harness the market in ways that produce desirable social outcomes - decent wages, good jobs and affordable health care. Dean Baker is co-director of the Center for Economic and Policy Research.
Download or read book Sociomedical Perspectives on Patient Care written by Jeffrey M. Clair and published by University Press of Kentucky. This book was released on 1993-08-10 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social change has placed new demands on the practice of medicine, altering almost every aspect of patient care relationships. Just as medicine was encouraged to embrace the biological sciences some 100 years ago, recent directives indicate the importance of the social sciences in understanding biomedical practice. Humanistic challenges call for changes in curative and technological imperatives. In this book, social scientists contribute to such challenges by using social evidence to indicate appropriate new goals for health care in a changing environment. This book was designed to stimulate and challenge all those concerned with the human interactions that constitute medical practice. To encompass a wide range of topics, the authors include researchers; practicing physicians from the specialties of family, general, geriatric, pediatric, and oncological medicine; social and behavioral scientists; and public health representatives. Cutting across disciplinary boundaries, they explore the ethical, economic, and social aspects of patient care. These essays draw on past studies of the patient-doctor relationship and generate new and important questions. They address social behavior in patient care as a way to approach theoretical issues pertinent to the social and medical sciences. The authors also use social variables to study patient care and suggest new areas of sociomedical inquiry and new approaches to medical practice, education, and research. Its cross-disciplinary approach and jargon-free writing make this book an important and accessible tool for physician, scholar, and student.
Download or read book Saving Normal written by Allen Frances, M.D. and published by Harper Collins. This book was released on 2013-05-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: From "the most powerful psychiatrist in America" (New York Times) and "the man who wrote the book on mental illness" (Wired), a deeply fascinating and urgently important critique of the widespread medicalization of normality Anyone living a full, rich life experiences ups and downs, stresses, disappointments, sorrows, and setbacks. These challenges are a normal part of being human, and they should not be treated as psychiatric disease. However, today millions of people who are really no more than "worried well" are being diagnosed as having a mental disorder and are receiving unnecessary treatment. In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation. We also shift responsibility for our mental well-being away from our own naturally resilient and self-healing brains, which have kept us sane for hundreds of thousands of years, and into the hands of "Big Pharma," who are reaping multi-billion-dollar profits. Frances cautions that the new edition of the "bible of psychiatry," the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5), will turn our current diagnostic inflation into hyperinflation by converting millions of "normal" people into "mental patients." Alarmingly, in DSM-5, normal grief will become "Major Depressive Disorder"; the forgetting seen in old age is "Mild Neurocognitive Disorder"; temper tantrums are "Disruptive Mood Dysregulation Disorder"; worrying about a medical illness is "Somatic Symptom Disorder"; gluttony is "Binge Eating Disorder"; and most of us will qualify for adult "Attention Deficit Disorder." What's more, all of these newly invented conditions will worsen the cruel paradox of the mental health industry: those who desperately need psychiatric help are left shamefully neglected, while the "worried well" are given the bulk of the treatment, often at their own detriment. Masterfully charting the history of psychiatric fads throughout history, Frances argues that whenever we arbitrarily label another aspect of the human condition a "disease," we further chip away at our human adaptability and diversity, dulling the full palette of what is normal and losing something fundamental of ourselves in the process. Saving Normal is a call to all of us to reclaim the full measure of our humanity.
Download or read book Cellular Respiration and Carcinogenesis written by Shireesh Apte and published by Springer Science & Business Media. This book was released on 2008-12-18 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Respiration and Carcinogenesis presents leading experts in the field as it informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanism or pathways of cellular respiration; oxidative phosphorylation and glycolysis. The editors and contributing authors proficiently and unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer. While it remains true that there are no universal truths in cancer, Cellular Respiration and Carcinogenesis opens the dialogue that the etiology of cancer can usually be associated with, and significantly attributed to the failure of one or multiple pathways of oxidative phosphorylation (cellular respiration) to normally burn fuel to generate energy, vis-à-vis the Warburg hypothesis. Keeping with its cutting-edge nature, Cellular Respiration and Carcinogenesis provides the first glimpse to a cautionary evidence based counterbalance to the recent and rapidly proliferating notion that utilization of fuel primarily via glycolysis is a hallmark of cancer development.
Download or read book The Social Impact of the Chernobyl Disaster written by David R. Marples and published by Springer. This book was released on 1988-09-01 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: A personal interpretation of the impact of the Chernobyl disaster both in the Soviet Union and the West, examining the environmental consequences, Soviet media coverage, reconstruction of life in the disaster zone (including the city built for Chernobyl workers) and safety changes in the industry.
Download or read book The Routledge History of Literature in English written by Ronald Carter and published by Psychology Press. This book was released on 2001 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a guide to the main developments in the history of British and Irish literature, charting some of the main features of literary language development and highlighting key language topics.
