Download or read book The Foundation of Precision Medicine Integration of Electronic Health Records with Nenomics Through Basic Clinical and Translational Research written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook contains the 19 articles that were part of a Special Topic in Frontiers in Genetics entitled "Genetics Research in Electronic Health Records Linked to DNA Biobanks". The Special Issue was published on-line in 2014-2015 and contained papers representing the diverse research ongoing in the integration of electronic health records (EHR) with genomics through basic, clinical, and translational research. We have divided the eBook into four Chapters. Chapter 1 describes the Electronic Medical Records and Genomics (eMERGE) network and its contri-bution to genomics. It highlights methodological questions related to large data sets such as imputation and population stratification. Chapter 2 describes the results of genetic studies on different diseases for which all the phenotypic information was extracted from the EHR with highly specific ePhenotyping algorithms. Chapter 3 focuses on more complex analyses of the genome including copy number variants (CNV), pleiotropy com-bined with phenome-wide association studies (PheWAS), and epistasis (gene-gene interactions). Chapter 4 discusses the use of genetic data together with EHR-derived clinical data in clinical settings, and how to return genetic results to patients and providers. It also contains a comprehensive review on genetic risk scores. We have included mostly Original Research Articles in the eBook, but also Reviews and Methods papers on the relevant topics of analyzing and integrating genomic data. The release of this eBook is timely, since several countries are launching Precision Medicine initiatives. Precision Medicine is a new concept in patient care taking into account individual variability in genetic, environmental and lifestyle factors, when treating diseases or trying to prevent them from developing. It has become an important focus for biomedical, clinical and translational informatics. The papers presented in this eBook are well positioned to educate the readers about Precision Medicine and to demonstrate the potential study designs, methods, strategies, and applications where this type of research can be performed successfully. The ultimate goal is to improve diagnostics and provide better, more targeted care to the patient.
Download or read book The Foundation of Precision Medicine Integration of Electronic Health Records with Genomics Through Basic Clinical and Translational Research written by Mariza de Andrade and published by Frontiers Media SA. This book was released on 2016-06-30 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook contains the 19 articles that were part of a Special Topic in Frontiers in Genetics entitled “Genetics Research in Electronic Health Records Linked to DNA Biobanks”. The Special Issue was published on-line in 2014-2015 and contained papers representing the diverse research ongoing in the integration of electronic health records (EHR) with genomics through basic, clinical, and translational research. We have divided the eBook into four Chapters. Chapter 1 describes the Electronic Medical Records and Genomics (eMERGE) network and its contri-bution to genomics. It highlights methodological questions related to large data sets such as imputation and population stratification. Chapter 2 describes the results of genetic studies on different diseases for which all the phenotypic information was extracted from the EHR with highly specific ePhenotyping algorithms. Chapter 3 focuses on more complex analyses of the genome including copy number variants (CNV), pleiotropy com-bined with phenome-wide association studies (PheWAS), and epistasis (gene-gene interactions). Chapter 4 discusses the use of genetic data together with EHR-derived clinical data in clinical settings, and how to return genetic results to patients and providers. It also contains a comprehensive review on genetic risk scores. We have included mostly Original Research Articles in the eBook, but also Reviews and Methods papers on the relevant topics of analyzing and integrating genomic data. The release of this eBook is timely, since several countries are launching Precision Medicine initiatives. Precision Medicine is a new concept in patient care taking into account individual variability in genetic, environmental and lifestyle factors, when treating diseases or trying to prevent them from developing. It has become an important focus for biomedical, clinical and translational informatics. The papers presented in this eBook are well positioned to educate the readers about Precision Medicine and to demonstrate the potential study designs, methods, strategies, and applications where this type of research can be performed successfully. The ultimate goal is to improve diagnostics and provide better, more targeted care to the patient.
Download or read book Genomics Enabled Learning Health Care Systems written by Institute of Medicine and published by National Academies Press. This book was released on 2015-07-08 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inclusion of genomic data in a knowledge-generating health care system infrastructure is one promising way to harness the full potential of that information to provide better patient care. In such a system, clinical practice and research influence each other with the goal of improving the efficiency and effectiveness of disease prevention, diagnosis, and treatment. To examine pragmatic approaches to incorporating genomics in learning health care systems, the Institute of Medicine Roundtable on Translating Genomic-Based Research for Health hosted a workshop which convened a variety of stakeholder groups, including commercial developers, health information technology professionals, clinical providers, academic researchers, patient groups, and government and health system representatives, to present their perspectives and participate in discussions on maximizing the value that can be obtained from genomic information. The workshop examined how a variety of systems are capturing and making use of genomic data to generate knowledge for advancing health care in the 21st century. It also sought to evaluate the challenges, opportunities, and best practices for capturing or using genomic information in knowledge-generating health care systems. Genomics-Enabled Learning Health Care Systems summarizes the presentations and discussion of the workshop.
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Download or read book Clinical Data as the Basic Staple of Health Learning written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-14 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Successful development of clinical data as an engine for knowledge generation has the potential to transform health and health care in America. As part of its Learning Health System Series, the Roundtable on Value & Science-Driven Health Care hosted a workshop to discuss expanding the access to and use of clinical data as a foundation for care improvement.
Download or read book For the Record written by National Research Council and published by National Academies Press. This book was released on 1997-07-09 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: When you visit the doctor, information about you may be recorded in an office computer. Your tests may be sent to a laboratory or consulting physician. Relevant information may be transmitted to your health insurer or pharmacy. Your data may be collected by the state government or by an organization that accredits health care or studies medical costs. By making information more readily available to those who need it, greater use of computerized health information can help improve the quality of health care and reduce its costs. Yet health care organizations must find ways to ensure that electronic health information is not improperly divulged. Patient privacy has been an issue since the oath of Hippocrates first called on physicians to "keep silence" on patient matters, and with highly sensitive dataâ€"genetic information, HIV test results, psychiatric recordsâ€"entering patient records, concerns over privacy and security are growing. For the Record responds to the health care industry's need for greater guidance in protecting health information that increasingly flows through the national information infrastructureâ€"from patient to provider, payer, analyst, employer, government agency, medical product manufacturer, and beyond. This book makes practical detailed recommendations for technical and organizational solutions and national-level initiatives. For the Record describes two major types of privacy and security concerns that stem from the availability of health information in electronic form: the increased potential for inappropriate release of information held by individual organizations (whether by those with access to computerized records or those who break into them) and systemic concerns derived from open and widespread sharing of data among various parties. The committee reports on the technological and organizational aspects of security management, including basic principles of security; the effectiveness of technologies for user authentication, access control, and encryption; obstacles and incentives in the adoption of new technologies; and mechanisms for training, monitoring, and enforcement. For the Record reviews the growing interest in electronic medical records; the increasing value of health information to providers, payers, researchers, and administrators; and the current legal and regulatory environment for protecting health data. This information is of immediate interest to policymakers, health policy researchers, patient advocates, professionals in health data management, and other stakeholders.
Download or read book Clinical Research Informatics written by Rachel Richesson and published by Springer Science & Business Media. This book was released on 2012-02-10 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.
Download or read book Connected for Health written by Louise L. Liang and published by John Wiley & Sons. This book was released on 2010-05-17 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kaiser Permanente has implemented the largest nongovernmental electronic health record in the world, serving more than 8.6 million Kaiser Permanente members. Called KP HealthConnect, its impact on patient care outcomes, efficiency, safety, and patient engagement and satisfaction already is of intense interest throughout the health care industry. In this volume, Louise L. Liang, MD, who led the massive KP HealthConnect implementation, collects lessons learned from the organization's successful deployment strategy and highlights ways in which the new technological tools are changing and improving - the health care provided to patients and the operations and culture of the organization. Advance praise for Connected for Health "Health care transformation requires leadership and innovation. Connected for Health clearly shows there is no shortage of either at Kaiser Permanente. This is a must read for policy makers and practitioners as the lessons are of critical value if we are to achieve quality, affordable care for Americans." —H. Stephen Lieber, president and CEO, Healthcare Information and Management Systems Society "Connected for Health shares what Kaiser Permanente has learned so far in tapping the vast potential of electronic health records to improve care and expand the frontiers of medical research. It is a journey that should be of great interest to policy leaders in the United States and around the world." —Karen Davis, president, The Commonwealth Fund "This book is destined to become an important part of the critical dialogue on what reforming our health care system really means." —James J. Mongan, MD, Professor of Health Care Policy and Social Medicine, Harvard Medical School "Connected for Health shows how KP HealthConnect is facilitating great team-based care, getting quality right every time, getting patients activated, and freeing caregivers to connect as true healers with their patients." —Margaret E. O'Kane, president, National Committee for Quality Assurance "Effective implementation and use of health information technology is critical to improving the quality, safety, and affordability of health care. This book provides a great opportunity for others to learn from Kaiser Permanente's pioneering efforts." —Janet M. Corrigan, president and CEO, National Quality Forum
Download or read book Integrating Research and Practice written by Institute of Medicine and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient-Centered Clinical Research Network, or PCORnet, is a nation-wide patient-centered clinical research network intended to form a resource of clinical, administrative, and patient data that can be used to carry out observational and interventional research studies and enhance the use of clinical data to advance the learning health care system. The primary goal of the first phase of PCORnet will be to establish the data infrastructure necessary to do such research. In April and June 2014 the Institute of Medicine's Roundtable on Value and Science-Driven Health Care convened two workshops aimed at accelerating progress toward real-time knowledge generation through the seamless integration of clinical practice and research, one of the fundamental concepts of a continuously learning health system, centered on the development of the PCORnet.
Download or read book New Perspectives in Medical Records written by Giovanni Rinaldi and published by Springer. This book was released on 2017-03-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides innovative practical suggestions regarding the production and management of medical records that are designed to address the inconsistencies and errors that have been highlighted especially in relation to national eHealth programs. Challenges and lessons that have emerged from the use of clinical information and the design of medical records are discussed, and principles underpinning the implementation of health IT are critically examined. New trends in the use of clinical data are explored in depth, with analysis of issues relating to integration and sharing of patient information, data visualization, big data analytics, and the requirements of modern electronic health records. The spirit pervading the book is one of co-production, in which the needs of practitioners are taken into account from the outset. Readers will learn the basic concepts of how clinical information emanating from the doctor–patient relationship can be effectively integrated with genetic and environmental data and analyzed by complex algorithms with the goal of improving medical decision making and patient care. The book, written by European experts and researchers, will be of interest to all stakeholders in the field, including doctors, technicians, and policy makers.
Download or read book Fundamentals of Clinical Data Science written by and published by . This book was released on 2019 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Capturing Social and Behavioral Domains and Measures in Electronic Health Records written by Committee on the Recommended Social and Behavioral Domains and Measures for Electronic Health Records and published by . This book was released on 2015-01-08 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Determinants of health - like physical activity levels and living conditions - have traditionally been the concern of public health and have not been linked closely to clinical practice. However, if standardized social and behavioral data can be incorporated into patient electronic health records (EHRs), those data can provide crucial information about factors that influence health and the effectiveness of treatment. Such information is useful for diagnosis, treatment choices, policy, health care system design, and innovations to improve health outcomes and reduce health care costs. "Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2" identifies domains and measures that capture the social determinants of health to inform the development of recommendations for the meaningful use of EHRs. This report is the second part of a two-part study. The Phase 1 report identified 17 domains for inclusion in EHRs. This report pinpoints 12 measures related to 11 of the initial domains and considers the implications of incorporating them into all EHRs. This book includes three chapters from the Phase 1 report in addition to the new Phase 2 material. Standardized use of EHRs that include social and behavioral domains could provide better patient care, improve population health, and enable more informative research. The recommendations of "Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2" will provide valuable information on which to base problem identification, clinical diagnoses, patient treatment, outcomes assessment, and population health measurement.
Download or read book Research Methods in Human Development written by Paul C. Cozby and published by WCB/McGraw-Hill. This book was released on 1989 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: For undergradute social science majors. A textbook on the interpretation and use of research. Annotation copyright Book News, Inc. Portland, Or.
Download or read book Disease Control Priorities Third Edition Volume 2 written by Robert Black and published by World Bank Publications. This book was released on 2016-04-11 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.
Download or read book The Coding Manual for Qualitative Researchers written by Johnny Saldana and published by SAGE. This book was released on 2009-02-19 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Coding Manual for Qualitative Researchers is unique in providing, in one volume, an in-depth guide to each of the multiple approaches available for coding qualitative data. In total, 29 different approaches to coding are covered, ranging in complexity from beginner to advanced level and covering the full range of types of qualitative data from interview transcripts to field notes. For each approach profiled, Johnny Saldaña discusses the method’s origins in the professional literature, a description of the method, recommendations for practical applications, and a clearly illustrated example.
Download or read book Medicine Preserving the Passion written by Phil R. Manning and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Medicine: Preserving the Passion, Phil R. Manning, a pioneer and recognized authority in continuing medical education, and Lois DeBakey, a passionate advocate of critical reasoning and leading scholar in scientific communication, endeavor to shift the focus in lifelong learning from group exercises in a lecture hall to self-directed, practice-related activities. Al though most experts have applauded this new concept, few publications have addressed methods for implementation. The Manning-DeBakey book describes such methods as devised by outstanding clinicians and acade micians to obtain educational benefit from their clinical experience. Some techniques inspired by quality assurance, for example, these master cli nicians have used successfully to improve their knowledge, skills, and patient care. This book not only identifies the primary concerns in con tinuing medical education, but also offers sound recommendations and effective solutions and suggests future directions and approaches. The authors have analyzed the continuing educational practices of phy sicians in a wide range of environments, from small communities to the most acclaimed medical centers, and have extracted additional advice from the writings of past authorities like Osler. The resulting concepts will un doubtedly attract wide public attention. Office practice audit, self-directed learning, case indexing, patient education, computer-assisted education, and collegial networks, as well as regular reading, writing, and teaching, are among the successful methods described by physicians and surgeons who exemplify the highest standards of medical practice.
Download or read book Basic and Clinical Pharmacology written by Bertram G. Katzung and published by . This book was released on 2001 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.
