Download or read book The Evolution of Vertebrate Blood Clotting written by Russell F. Doolittle and published by University Science Books. This book was released on 2012-11-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: llluminated by a great assortment of original illustrations, this remarkable book charts the step-by-step evolution of vertebrate blood coagulation. Intended for readers with a background in biological science, it is specifically targeted for those in the field of molecular evolution as well as for researchers in the area of blood clotting. After providing some general background in the areas of blood clotting, protein structure, animal systematics, and simple genomics, the book focusses in on the search for blood clotting genes in the genomes of non-mammalian vertebrates, including fish, amphibians, reptiles and birds. The inventory of genes found allows a reconstruction of events culminating in the complex clotting system observed in humans and other mammals. Also examined are the genomes of protochordates like the sea squirt, leading to conjecture about how blood clotting was first initiated. The orderly way in which gene duplications provided new genes for fine-tuning the system serves as a model for how complex physiological systems in general have evolved. The book ends with suggestions for specific genetic engineering experiments that can be done to illustrate how molecular evolution works. An extensive glossary and guide to the current literature combine to make this book ideal for course use as well as for self study.
Download or read book Comparative Hemostasis in Vertebrates written by Jessica H. Lewis and published by Springer Science & Business Media. This book was released on 1996-05-31 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author examines hemostasis in animals from all seven major vertebrate classes. Her research provides unique insights into the phylogenetic development of the various phases and components of hemostasis. This monograph is a valuable reference for students, researchers, and teachers of biology, zoology, veterinary science, and human medicine.
Download or read book Comparative Hemostasis in Vertebrates written by James H. Lewis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author examines hemostasis in animals from all seven major vertebrate classes. Her research provides unique insights into the phylogenetic development of the various phases and components of hemostasis. This monograph is a valuable reference for students, researchers, and teachers of biology, zoology, veterinary science, and human medicine.
Download or read book Thank Evolution for God written by Louis W. Perry and published by Xlibris Corporation. This book was released on 2012-03-21 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: THANK EVOLUTION FOR GOD Nature and God’s Creations and Designs Biological evolution of living organisms, including man, as described by Darwin’s Theory of natural selection is settled science for most scientists, philosophers and evolutionary biologist allowing them to declare that in the science classroom to Thank Evolution for God. But man’s evolution taught in public schools remains a contentious issue for many Christians today who declare Thank God for Evolution. The question, who to thank for the evolution of man, his morals and gods, God or Nature? is addressed in light of Nature’s theories describing advances in evolutionary biology, neuroscience and neurophilosophy which are compared to God’s Words as interpreted by Christians; Fundamentalist, Liberal and Progressive. The case for Nature is based on the works of leading evolutionary biologists, neuroscientists, physicists and philosophers. God’s case is extracted from the books of five leading Christian authors who have addressed Darwin’s Theory in light of the demands of their religion. The answer to the question of who to thank has evolved from ten years of lectures given by the author and the responses of hundreds of students of many religious persuasions to lectures on the ‘Conflicts of Religion with Science and Democracy’ at the University of California San Diego.
Download or read book The Mystery of Evolutionary Mechanisms written by Robert F. Shedinger and published by Wipf and Stock Publishers. This book was released on 2019-06-28 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is Darwinian evolution really the most successful scientific theory ever proposed--or even the best idea anyone has ever had, as Daniel Dennett once put it? The Mystery of Evolutionary Mechanisms provides a comprehensive critical reading of the literature of evolutionary biology from Darwin to Dobzhansky to Dawkins, revealing this popular account of evolution to be a grand narrative of Darwinian triumph that greatly overstates the empirical validity of modern evolutionary theory. The mechanisms driving the evolutionary process truly remain a mystery more than one hundred fifty years after Origin of Species, a fact that can free religion scholars to think in more creative ways about the positive contributions religious reflection might make to our understanding of life's origin and diversity. The Mystery of Evolutionary Mechanisms calls for an embrace of mystery, understood not as an abdication of the scientific quest for truth but as a courageous and humble acknowledgment of the limits of human reason and an openness to a fundamentally religious orientation toward life.
Download or read book Bioengineering and Biomaterials in Ventricular Assist Devices written by Eduardo Guy Perpétuo Bock and published by CRC Press. This book was released on 2021-10-07 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support. FEATURES Establishes an area of intersection between engineering and medicine Shows process development from mechanical design to automation and control Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.
Download or read book Hemostasis and Thrombosis written by Victor J. Marder and published by Lippincott Williams & Wilkins. This book was released on 2012-12-27 with total page 5220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.
Download or read book Mechanisms in Blood Coagulation Fibrinolysis and the Complement System written by Torben Halkier and published by Cambridge University Press. This book was released on 1991 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account of the proteins involved in blood coagulation, fibrinolysis and the complement system. A major section of the book is devoted to each of these three systems, with separate chapters dealing in detail with structural aspects and different functional processes. Topics covered in the blood coagulation section include the activation of factors IX and X and prothrombin, and the formation and stabilisation of fibrin. The fibrinolysis section includes the activation of plasminogen, the degradation of fibrin and the regulation of fibrinolysis. The complement system itself is covered in chapters dealing with classical activation, alternative activation, the lytic complex and the regulatory processes involved. In addition, one section deals with special topics, including the kinin system, signal peptides, haemostasis, and the evolution of protein structure. This volume will be of use to researchers and advanced students in the fields of haematology, immunology and clinical chemistry.
Download or read book The Nature of Nature written by Bruce Gordon and published by Open Road Media. This book was released on 2014-04-29 with total page 1057 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intellectual and cultural battles now raging over theism and atheism, conservatism and secular progressivism, dualism and monism, realism and antirealism, and transcendent reality versus material reality extend even into the scientific disciplines. This stunning new volume captures this titanic clash of worldviews among those who have thought most deeply about the nature of science and of the universe itself. Unmatched in its breadth and scope, The Nature of Nature brings together some of the most influential scientists, scholars, and public intellectuals—including three Nobel laureates—across a wide spectrum of disciplines and schools of thought. Here they grapple with a perennial question that has been made all the more pressing by recent advances in the natural sciences: Is the fundamental explanatory principle of the universe, life, and self-conscious awareness to be found in inanimate matter or immaterial mind? The answers found in this book have profound implications for what it means to do science, what it means to be human, and what the future holds for all of us.
Download or read book Translational Animal Models in Drug Discovery and Development written by Xinkang Wang and published by Bentham Science Publishers. This book was released on 2012-10-03 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene expression, heterogeneity of disease conditions, etc.), not all the preclinical models are able to represent the pathophysiological conditions in human diseases. Therefore, partly due to the lack of congruency between animal and human disease models, several proposed therapeutic agents in the past decades have been demonstrated to be effective in preclinical models but failed in clinical studies. This e-book focuses on animal models of diseases from a translational perspective and highlights the key advantages and limitations of each model described to facilitate drug discovery and development. A unique feature of the volume is that it contains a selection of details disease models in various therapeutic niches with significant unmet medical needs, including inflammation, neurological diseases, cardiovascular and metabolic diseases, and oncology. This e-book is, therefore, of considerable value to researchers and clinicians involved in drug discovery and development as well as pathology.
Download or read book The Evolution Controversy written by Thomas B. Fowler and published by Baker Academic. This book was released on 2007-08-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the emotional debate surrounding evolution, it is often difficult to cut through the competing agendas to gain an unbiased understanding of the scientific issues involved. The Evolution Controversy provides a resource for doing so. The authors leave aside the profound philosophical and religious issues involved in the controversy in favor of a balanced and critical examination of the four major schools of thought involved: Neo-Darwinism, Creationism, Intelligent Design, and Meta-Darwinism. The focus is on an objective evaluation of the scientific merits of each school, as well as an examination of areas of agreement and disagreement among the schools. The goal is to equip readers, whether students, church leaders, or the general public, to come to their own informed conclusions.
Download or read book The Serpin Family written by Margarethe Geiger and published by Springer. This book was released on 2015-11-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but also in insects, worms, plants and viruses.
Download or read book Thrombosis and Bleeding written by Cecil Hougie and published by Trafford Publishing. This book was released on 2004-12 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The maintenance of the fluid state of the blood in the blood vessels is essential for blood flow and life, but almost equally important is the mechanism to stem the loss of blood following injury and trauma. The subject of blood clotting and thrombosis has long been a difficult and confusing one. However progress in the field during the last half century or so has been phenomenal, almost unbelievably so, and many previously inexplicable findings now have rational explanations. This book is primarily an attempt to give the reader a short overall view of the mechanisms involved in these vital processes and their significance both in health and disease. The approach has been a historical one in the sense that I have related the key discoveries more or less in the order in which they evolved. I have done this to enable me to introduce new data in incremental steps and to avoid overwhelming the reader with new information. I have also sprinkled the book with anecdotes and historical events to make the narrative more interesting reading. The goal throughout was to write a book that was informative and could be understood by the general reader.
Download or read book Evolution Explanation Ethics and Aesthetics written by Francisco J. Ayala and published by Academic Press. This book was released on 2016-07-21 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution, Explanation, Ethics and Aesthetics: Towards a Philosophy of Biology focuses on the dominant biological topic of evolution. It deals with the prevailing philosophical themes of how to explain the adaptation of organisms, the interplay of chance and necessity, and the recurrent topics of emergence, reductionism, and progress. In addition, the extensively treated topic of how to explain human nature as a result of natural processes and the encompassed issues of the foundations of morality and the brain-to-mind transformation is discussed. The philosophy of biology is a rapidly expanding field, not more than half a century old at most, and to a large extent is replacing the interest in the philosophy of physics that prevailed in the first two-thirds of the twentieth century. Few texts available have the benefit of being written by an eminent biologist who happens to be also a philosopher, as in this work. This book is a useful resource for seminar courses and college courses on the philosophy of biology. Researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity will also be interested in this work, as will those in human biology and issues such as ethics, religion, and the human mind, along with professional philosophers of science and those concerned with such issues as whether evolution is compatible with religion and/or where morality comes from. Presents the unique perspective of a distinguished biologist with extensive experience in the field who has published much about the subject in a wide variety of journals and edited volumes Covers the philosophical issues related to evolution and biology in an approachable and readable style Includes the most up-to-date treatment of this burgeoning, exciting field within biology Provides the ideal guide for researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity
Download or read book Recent Advances in Thrombosis and Hemostasis written by K. Tanaka and published by Springer Science & Business Media. This book was released on 2009-01-15 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hypertension, and obesity are the leading causes of morbidity and mortality. They have become urgent medical problems with serious economic consequences in industrialized and devel- ing countries alike. At the same time, the impact of molecular biology and genetics on our understanding of thrombosis and hemostasis is rapidly growing stronger as well as our knowledge of regeneration and development of specific tissues, organs, and embryos. Researchers are also constantly learning more about cardiovascular diseases as well as regulatory mechanisms for various intrinsic and extrinsic stimuli in viable tissues. In this volume, our intention has been to present the latest relevant information in molecular biology and genetics as well as the clinical implications of a better understanding of pathophysiology, novel diagnostic methodologies, and therapeutic applications for new methods of prevention in thrombosis/hemostasis and related disorders, including atherosclerosis. The dramatic advances in knowledge of thrombosis/hemostasis and vascular biology since the first publication of Recent Advances in Thrombosis and Fibrinolysis, edited with Japanese colleagues, in 1991, have required extensive revision in order to highlight and review recent progress in the field. The editors also gratefully welcome the seven distinguished non Japanese authors, who, with their valuable contributions on subjects beyond the coverage by Japanese authors, have made this new edition truly international.
Download or read book Design by Evolution written by Philip F. Hingston and published by Springer Science & Business Media. This book was released on 2008-09-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution is Nature’s design process. The natural world is full of wonderful examples of its successes, from engineering design feats such as powered flight, to the design of complex optical systems such as the mammalian eye, to the merely stunningly beautiful designs of orchids or birds of paradise. With increasing computational power, we are now able to simulate this process with greater fidelity, combining complex simulations with high-performance evolutionary algorithms to tackle problems that used to be impractical. This book showcases the state of the art in evolutionary algorithms for design. The chapters are organized by experts in the following fields: evolutionary design and "intelligent design" in biology, art, computational embryogeny, and engineering. The book will be of interest to researchers, practitioners and graduate students in natural computing, engineering design, biology and the creative arts.
Download or read book The Science of Evolution and the Myth of Creationism written by Ardea Skybreak and published by Insight Press, Inc. This book was released on 2006-09-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clear, lively, and systematic presentation examines the scientific evidence for evolution and reaches for the widest possible audience—from scientific minds to those with no science background at all. Forcefully rejecting creationist objections to evolution and including a critique of Intelligent Design, it argues that they are part of a larger social agenda. With discussion that celebrates the fascination to be found in studying the diversity and complexity of life, this examination suggests with some urgency that the science of evolution is crucial to the existence of science itself.
