Download or read book The Era of Precision Medicine Genetics Pharmacy and Personalized Health written by Edenilson Brandl and published by Edenilson Brandl. This book was released on with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the fascinating field of precision medicine and its role in understanding and treating genetic diseases in various systems and organs of the human body. Throughout the chapters, topics such as precision medicine in the context of developmental diseases, nutrigenomics and its relationship to diet personalization, pulmonary diseases, musculoskeletal diseases, genetic diseases of the cardiovascular system, and genetic diseases of the hepatic system are explored. In addition, subjects such as the application of genetic tests in precision medicine, analysis of genetic variants, precision medicine in women's health, rare genetic diseases, dermatological diseases, nervous system diseases, renal system diseases and metabolism diseases are addressed. . The book also explores the role of epigenetics in precision medicine, highlighting how modifications to the genetic environment can influence disease development and progression. In addition, topics such as allergic diseases, genetic diseases of the respiratory system and genetic diseases of the musculoskeletal system are discussed. As a comprehensive guide, this book provides valuable insights into precision medicine and its impact on clinical practice in the quest for more accurate diagnoses and personalized treatments. It is essential reading for healthcare professionals, researchers, and students interested in the field of medical genetics and its applications in the era of precision medicine.
Download or read book Pharmacogenomics in Precision Medicine written by Weimin Cai and published by Springer Nature. This book was released on 2020-06-12 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
Download or read book Economic Dimensions of Personalized and Precision Medicine written by Ernst R. Berndt and published by University of Chicago Press. This book was released on 2019-04-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Download or read book Personalised Health Care written by Stefania Boccia and published by Springer Nature. This book was released on 2020-11-23 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practitioners are increasingly adopting a personalised medicine approach to individually tailored patient care, especially disease diagnosis and treatment with the use of biomarkers. However, development and implementation of such approaches to chronic disease prevention need further investigation and concerted efforts for proper use in healthcare systems. This book provides high-quality, multidisciplinary knowledge from research in personalised medicine, specifically personalised prevention of chronic disease. It addresses different perspectives of prevention in the field, and is the outcome of a four-year work of the Personalized prevention of Chronic Disease (PRECeDI) Consortium, a multi-disciplinary and multi-professional team of experts. The Consortium jointly agreed to document and address the five aspects or domains of personalised medicine and prevention as individual chapters: Identification of biomarkers for the prevention of chronic disease Evaluation of predictive genomic applications Ethico-legal and policy issues surrounding personalised medicine Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis Identification of organisational models for the provision of predictive genomic applications The book focuses on the Consortium's recommendations that are derived from each of these domains based on up-to-date evidence and research that the authors write, follow, and systematically organise and report. Personalisation of health care is, eventually, a driver of innovation in research and healthcare systems. With this SpringerBrief on Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, the Consortium provides further evidence of the clinical validity and utility of personalised medicine with special emphasis on the prevention of chronic diseases. The book is a useful resource for policy makers, industry and healthcare professionals, scientists, technology-sector professionals, investors, citizens, and private companies that need proper advice to realise the potential of personalised medicine.
Download or read book Personalized Medicine Optimizing Treatment with the Right Drug for the Right Patient and at the Right Dose through Pharmacogenomics written by PATHAN AZHER KHAN and published by Pristyn Research Solutions. This book was released on with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delineates the scientific concept of personalized medicine, recent FDA-approved drugs, personalized immunotherapy, and technological advancements, including 3D printing, next-gene sequencing, gene editing, etc. Moreover, it highlights the pivotal role of digital health and artificial intelligence as integral components in facilitating personalized patient care and fostering collaboration between patients and healthcare systems. Finally, it explores the practical application of personalized medicine in clinical settings through the analysis of several case studies. Overall advance in this era of precision healthcare, the transformative potential of personalized medicine in clinical practice is poised to revolutionize the landscape of modern medicine.
Download or read book Clinical Decision Support for Pharmacogenomic Precision Medicine written by Beth Devine and published by Academic Press. This book was released on 2022-06-14 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation offers overviews, methods and strategies for translating genomic medicine to clinical practice. The book's authors explore incorporating pharmacogenetics into electronic health records, CDS methods and infrastructure for delivery, economic evaluation, the hospital administrations’ role and needs in integration, and patient counseling aspects. The book empowers clinicians, researchers, translational scientists, and data and IT experts to effectively navigate the complex landscape of CDS for pharmacogenomic precision medicine. Illustrative case studies of existing gene networks include CSER, eMERGE, the IGNITE network, DIGITIZE, the CDS Learning Network (RTI), ClinGen, Ubiquitous and CDS Hooks. Offers an applied, case-driven discussion of CDS for pharmacogenomic precision medicine Illustrates key concepts, contemporary developments, and future directions using examples of existing gene networks Features contributions from leading voices in precision medicine and clinical decision support
Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2009-08-29 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author’s efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.
Download or read book Greek Medicine from Hippocrates to Galen written by Jacques Jouanna and published by BRILL. This book was released on 2012-07-25 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes available in English translation a selection of Jacques Jouanna's papers on Greek and Roman medicine, ranging from the early beginnings of Greek medicine to late antiquity.
Download or read book Molecular Genetics and Personalized Medicine written by D. Hunter Best and published by Springer Science & Business Media. This book was released on 2012-01-04 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual’s specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.
Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine
Download or read book The Personalized Medicine Revolution written by Pieter Cullis and published by Greystone Books Ltd. This book was released on 2015 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cullis argues that personalized medicine, also known as precision medicine, is the biggest revolution of our time. By replacing the current one-size-fits-all approach to medicine with medical treatment based on a patient's unique molecular makeup, personalized medicine will radically change the role of doctors and patients and even the future of our species. Increasingly, instead of focusing on the treatment of chronic diseases, as they do today, doctors will focus on helping people prevent disease"--Amazon.com.
Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development
Download or read book Enabling Precision Medicine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-11-17 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop.
Download or read book Beyond the Genome Genetics Pharmacy and the Next Frontier in Medicine written by Edenilson Brandl and published by Edenilson Brandl. This book was released on with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Welcome to a fascinating dive into the world of genetics and precision medicine! In this book, we will explore a wide range of topics related to these areas of science that are revolutionizing the way we understand and approach human and animal health. Genetics has been a subject of fascination and study for decades, but recent technological and scientific advances have allowed for an even deeper understanding of the secrets of our genetic code. With the sequencing of the human genome and the discovery of new genes and genetic variants, we have entered an exciting era of precision medicine, in which treatments are customized based on each patient's individual genetic characteristics. Throughout this book, we will explore the most relevant and promising topics in genetics and precision medicine in different areas of healthcare. From its application in gastrointestinal medicine, through the role of genetics in cancer and its impact on psychosomatic medicine, assisted reproduction, liver disease, infectious diseases, contraception and sports medicine, to gene therapy for cancer and the applications of genes in medicine. We will also address ethical issues related to gene editing, the influence of the environment on gene expression through epigenetics and its application in tropical medicine. Additionally, we'll explore the exciting field of aesthetic medicine and how genetics and precision medicine are transforming animal health care into precision veterinary medicine. This book aims to provide a comprehensive and accessible overview of these complex topics, presenting the concepts clearly and highlighting the latest advances in the field. We hope it piques your interest, sparks your curiosity, and motivates you to explore further the incredible advances and future prospects of genetics and precision medicine. Get ready for a thrilling journey through the intricate details of DNA, the scientific discoveries that are changing medicine, and the inspiring stories of how genetics is transforming people's lives. Enjoy reading and allow yourself to discover the secrets and wonders of our genetic code!
Download or read book Personalized Medicine written by Fouad Sabry and published by One Billion Knowledgeable. This book was released on 2022-10-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: What Is Personalized Medicine A medical model known as personalized medicine, which is also known as precision medicine, categorizes patients into distinct groups, and then tailors medical decisions, practices, interventions, and/or products to each individual patient based on how they are expected to react to treatment or their likelihood of developing a disease. Personalized medicine is also known as precision medicine. Although the terms personalized medicine, precision medicine, stratified medicine, and P4 medicine are often used interchangeably to describe this concept, some authors and organizations use these expressions separately to indicate particular nuances. Personalized medicine refers to the practice of tailoring medical treatment to each individual patient. Precision medicine refers to the practice of treating patients based How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Personalized medicine Chapter 2: Pharmacogenomics Chapter 3: MammaPrint Chapter 4: Medical genetics Chapter 5: Biomarker (medicine) Chapter 6: Biomarker (cell) Chapter 7: Predictive medicine Chapter 8: Public health genomics Chapter 9: Cancer Genome Project Chapter 10: Personal genomics Chapter 11: Cancer biomarker Chapter 12: Icahn Genomics Institute Chapter 13: Molecular pathological epidemiology Chapter 14: Molecular diagnostics Chapter 15: Precision medicine Chapter 16: Toxgnostics Chapter 17: Predictive genomics Chapter 18: Clinicogenomics Chapter 19: Elective genetic and genomic testing Chapter 20: Personalized onco-genomics Chapter 21: Cancer pharmacogenomics (II) Answering the public top questions about personalized medicine. (III) Real world examples for the usage of personalized medicine in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of personalized medicine' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of personalized medicine.
Download or read book Advancing Healthcare Through Personalized Medicine written by Priya Hays and published by Springer Nature. This book was released on 2021-09-27 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.
