Download or read book Single Neuron Studies of the Human Brain written by Itzhak Fried and published by MIT Press. This book was released on 2014-06-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena. In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field. The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts. Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rüdiger Köhling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Download or read book Observed Brain Dynamics written by Partha Mitra and published by Oxford University Press. This book was released on 2007-12-07 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biomedical sciences have recently undergone revolutionary change, due to the ability to digitize and store large data sets. In neuroscience, the data sources include measurements of neural activity measured using electrode arrays, EEG and MEG, brain imaging data from PET, fMRI, and optical imaging methods. Analysis, visualization, and management of these time series data sets is a growing field of research that has become increasingly important both for experimentalists and theorists interested in brain function. Written by investigators who have played an important role in developing the subject and in its pedagogical exposition, the current volume addresses the need for a textbook in this interdisciplinary area. The book is written for a broad spectrum of readers ranging from physical scientists, mathematicians, and statisticians wishing to educate themselves about neuroscience, to biologists who would like to learn time series analysis methods in particular and refresh their mathematical and statistical knowledge in general, through self-pedagogy. It may also be used as a supplement for a quantitative course in neurobiology or as a textbook for instruction on neural signal processing. The first part of the book contains a set of essays meant to provide conceptual background which are not technical and shall be generally accessible. Salient features include the adoption of an active perspective of the nervous system, an emphasis on function, and a brief survey of different theoretical accounts in neuroscience. The second part is the longest in the book, and contains a refresher course in mathematics and statistics leading up to time series analysis techniques. The third part contains applications of data analysis techniques to the range of data sources indicated above (also available as part of the Chronux data analysis platform from http://chronux.org), and the fourth part contains special topics.

Download or read book Associative Memory Cells Basic Units of Memory Trace written by Jin-Hui Wang and published by Springer Nature. This book was released on 2019-09-10 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on associative memory cells and their working principles, which can be applied to associative memories and memory-relevant cognitions. Providing comprehensive diagrams, it presents the author's personal perspectives on pathology and therapeutic strategies for memory deficits in patients suffering from neurological diseases and psychiatric disorders. Associative learning is a common approach to acquire multiple associated signals, including knowledge, experiences and skills from natural environments or social interaction. The identification of the cellular and molecular mechanisms underlying associative memory is important in furthering our understanding of the principles of memory formation and memory-relevant behaviors as well as in developing therapeutic strategies that enhance memory capacity in healthy individuals and improve memory deficit in patients suffering from neurological disease and psychiatric disorders. Although a series of hypotheses about neural substrates for associative memory has been proposed, numerous questions still need to be addressed, especially the basic units and their working principle in engrams and circuits specific for various memory patterns. This book summarizes the developments concerning associative memory cells reported in current and past literature, providing a valuable overview of the field for neuroscientists, psychologists and students.

Download or read book From Conditioning to Conscious Recollection written by Howard Eichenbaum and published by Oxford University Press. This book was released on 2004-11-18 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge book offers a theoretical account of the evolution of multiple memory systems of the brain. The authors conceptualize these memory systems from both behavioral and neurobiological perspectives, guided by three related principles. First, that our understanding of a wide range of memory phenomena can be advanced by breaking down memory into multiple forms with different operating characteristics. Second, that different forms of memory representation are supported by distinct brain pathways with circuitry and neural coding properties. Third, that the contributions of different brain systems can be compared and contrasted by distinguishing between dedicated (or specific) and elaborate (or general) memory systems. A primary goal of this work is to relate the neurobiological properties of dedicated and elaborate systems to their neuropsychological counterparts, and in so doing, account for the phenomenology of memory, from conditioning to conscious recollection.

Download or read book The Cognitive Neuroscience of Memory written by Amanda Parker and published by Psychology Press. This book was released on 2005-08-18 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in techniques available to memory researchers have led to a rapid expansion in the field of cognitive neuroscience of memory. This book provides accessible coverage of four key areas of recent advance, including research on functional imaging, electrophysiological and lesion studies, and developments from the computational modelling approach. The first section reviews functional imaging studies in humans, with particular emphasis on how imaging methods have clarified the cortical areas involved in memory formation and retrieval. The second section describes electrophysiological and lesion research in monkeys, where lesion and disconnection studies are rapidly adding to our knowledge of both information processing and modulatory aspects of memory formation. In the third section, electrophysiological and lesion studies in rats are reviewed allowing for a detailed study of the role of novelty and exploration in memory formation. The final section reviews current research in computational modelling which has allowed the development of new theoretical and experimental approaches to the study of memory encoding and retrieval. This volume draws together the current developments in each field, allowing the synthesis of ideas and providing converging evidence from a range of sources. It will be a useful resource for both advanced undergraduate and postgraduate students of psychology, as well as researchers in the field and anyone with an interest in cognitive neuroscience.

Download or read book The Cognitive Neuroscience of Working Memory written by Naoyuki Osaka and published by . This book was released on 2007 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only relatively recently that it has been possible to study the neural processes that might underlie working memory, leading to a proliferation of research in this domain. This volume brings together leading researchers from around the world to summarise current knowledge of this field.

Download or read book Cognitive Electrophysiology of Attention written by George R. Mangun and published by Academic Press. This book was released on 2013-08-31 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive Electrophysiology of Attention explores the fundamental mechanisms of attention and related cognitive functions from cognitive neuroscience perspectives. Attention is an essential cognitive ability that enables humans to process and act upon relevant information while ignoring distracting information, and the capacity to focus attention is at the core of mental functioning. Understanding the neural bases of human attention remains a key challenge for neuroscientists and psychologists, and is essential for translational efforts to treat attentional deficits in a variety of neurological and psychiatric disorders. Cognitive electrophysiology is at the center of a multidisciplinary approach that involves the efforts of psychologists, neuroscientists, neuropsychologists, psychiatrists, and neurologists to identify basic brain mechanisms and develop translational approaches to improve mental health. This edited volume is authored by leading investigators in the field and discusses methods focused on electrophysiological recordings in humans, including electroencephalography (EEG) and event-related potential (ERP) methods, and also incorporates evidence from functional magnetic resonance imaging (fMRI). Cognitive Electrophysiology of Attention illuminates specific models about attentional mechanisms in vision, audition, multisensory integration, memory, and semantic processing in humans. - Provides an exhaustive overview of attention processes, going from normal functioning to the pathological, and using a combination of methodological tools - An important reference for electrophysiology researchers looking at underlying attention processes rather than the methods themselves - Enables researchers across a broad range of cognitive-process and methodological specialties to stay current on particular hypotheses, findings, and methods - Edited and authored by the worldwide leaders in the field, affording the broadest, most expert coverage available

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Download or read book Average Evoked Potentials written by Emanuel Donchin and published by . This book was released on 1969 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods, results, and evaluation of research in average evoked potentials.

Download or read book Human Spatial Navigation written by Arne Ekstrom and published by Princeton University Press. This book was released on 2018-08-07 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to comprehensively explore the cognitive foundations of human spatial navigation Humans possess a range of navigation and orientation abilities, from the ordinary to the extraordinary. All of us must move from one location to the next, following habitual routes and avoiding getting lost. While there is more to learn about how the brain underlies our ability to navigate, neuroscience and psychology have begun to converge on some important answers. In Human Spatial Navigation, four leading experts tackle fundamental and unique issues to produce the first book-length investigation into this subject. Opening with the vivid story of Puluwat sailors who navigate in the open ocean with no mechanical aids, the authors begin by dissecting the behavioral basis of human spatial navigation. They then focus on its neural basis, describing neural recordings, brain imaging experiments, and patient studies. Recent advances give unprecedented insights into what is known about the cognitive map and the neural systems that facilitate navigation. The authors discuss how aging and diseases can impede navigation, and they introduce cutting-edge network models that show how the brain can act as a highly integrated system underlying spatial navigation. Throughout, the authors touch on fascinating examples of able navigators, from the Inuit of northern Canada to London taxi drivers, and they provide a critical lens into previous navigation research, which has primarily focused on other species, such as rodents. An ideal book for students and researchers seeking an accessible introduction to this important topic, Human Spatial Navigation offers a rich look into spatial memory and the neuroscientific foundations for how we make our way in the world.

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Download or read book Memory in the Cerebral Cortex written by Joaquin M. Fuster and published by Bradford Books. This book was released on 1999 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joaquín M. Fuster presents the insights of more than three decades of empirical research on the neural processes by which memory is formed, stored, and retrieved. In Memory in the Cerebral Cortex, Joaquín M. Fuster presents the insights of more than three decades of empirical research on the neural processes by which memory is formed, stored, and retrieved. Spanning the field from neuroanatomy to modeling, this book brings together all that we presently know about the role of the cerebral cortex of the primate in memory.

Download or read book Memory and Brain written by San Diego Larry R. Squire Professor of Psychiatry University of California and published by Oxford University Press, USA. This book was released on 1987-03-05 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading neuropsychologist, this book brings together the widely scattered psychological and neurobiological work on memory to create a definitive overview of current knowledge. Reflecting the many levels of analysis at which this work is taking place, the book proceeds from the synapse to a review of the function and structure of neural systems and the organization of cognition. Throughout, the author places current research in historical perspective, and identifies major ideas and themes that have emerged in recent years in order to provide a solid foundation for future investigations. The book is amply illustrated and contains a useful glossary. It will be of use in advanced undergraduate and graduate courses on memory, and to psychologists and neuroscientists desiring an account of memory that is informed equally by cognitive and neurobiological insights.

Download or read book Magnetoencephalography written by Selma Supek and published by Springer. This book was released on 2014-08-07 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

Download or read book Eye movement related brain activity during perceptual and cognitive processing written by Andrey R. Nikolaev and published by Frontiers E-books. This book was released on 2014-09-23 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recording and analysis of electrical brain activity associated with eye movements has a history of several decades. While the early attempts were primarily focused on uncovering the brain mechanisms of eye movements, more recent approaches use eye movements as markers of the ongoing brain activity to investigate perceptual and cognitive processes. This recent approach of segmenting brain activity based on eye movement behavior has several important advantages. First, the eye movement system is closely related to cognitive functions such as perception, attention and memory. This is not surprising since eye movements provide the easiest and the most accurate way to extract information from our visual environment and the eye movement system largely determines what information is selected for further processing. The eye movement-based segmentation offers a great way to study brain activity in relation to these processes. Second, on the methodological level, eye movements constitute a natural marker to segment the ongoing brain activity. This overcomes the problem of introducing artificial markers such as ones for stimulus presentation or response execution that are typical for a lab-based research. This opens possibilities to study brain activity during self-paced perceptual and cognitive behavior under naturalistic conditions such as free exploration of scenes. Third, by relating eye movement behavior to the ongoing brain activity it is possible to see how perceptual and cognitive processes unfold in time, being able to predict how brain activity eventually leads to behavior. This research topic illustrates advantages of the combined recording and analysis of eye movements and neural signals such as EEG, local field potentials and fMRI for investigation of the brain processes in humans and animals. The contributions include research papers, methodology papers and reviews demonstrating conceptual and methodological achievements in this rapidly developing field.

Download or read book Foundations of Human Memory written by Michael Jacob Kahana and published by Oxford University Press. This book was released on 2014-05-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundations of Human Memory provides an introduction to the scientific study of human memory with an emphasis on both the major theories of memory and the laboratory studies that have been used to test those theories and inspire their further development. Written with the undergraduate student in mind, the text assumes no specific background in the subject, but a general familiarity with scientific method and quantitative approaches to the treatment of data. Foundations of human memory is organized around the major empirical paradigms used to study memory in the laboratory and the theories used to explain data obtained using those paradigms. The text begins with a focus on memory for individual items, building up to memory for associations between items, and finally to memory for entire sequences of items and the problem of memory search. Several major theories of memory are considered in detail, including strength theory, summed-similarity theory, neural network based theories, retrieved-context theory, and theories based on the division of memory into separate short-term and long-term storage systems. The text emphasizes basic research over applied problems, but brings in real-world examples and neuroscientific evidence as appropriate.