Download or read book The Effects of Subthalamic Nucleus Deep Brain Stimulation on Behaviour and Cognition in Parkinson s Disease written by Pete Fleming and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of Subthalamic Nucleus Deep Brain Stimulation on Behaviour and Cognition in Parkinson s Disease written by Pete Fleming and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Stimulation written by Pierre Pollak and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proper selection of patients who will reliably benefit from deep brain stimulation (DBS) is critical to its success. This requires careful evaluation that should be delivered by an expert multidisciplinary team involving a movement disorder neurologist, a neurosurgeon, a neuropsychologist, and a psychiatrist. The most suitable candidates for DBS suffer from Parkinson’s disease with motor fluctuations and/or dyskinesias that are not adequately controlled with optimized medical therapy, or with medication-refractory tremor. During the best on-motor periods, gait difficulties, instability, and speech problems should be minimal, reflecting an excellent response to levodopa in the ideal candidate. The cognitive, psychiatric, and behavioral status must be normal or minimally affected, with the exception of dopamine agonist drug-induced impulse control disorders, which are usually improved after successful surgery and drug withdrawal. Moreover, the patients have no serious comorbidities. Most patients corresponding to this profile suffer from a relatively young onset of Parkinson’s disease, and are aged less than 70 years at the time of surgery. Indeed, most patients fall outside this ideal description, and the medical art is to appreciate for each patient the extent to which the alterations of these features can be accepted. Eventually, patients make their own decision from detailed information of their individualized risks and benefits of DBS. Patient expectations, cooperation, and familial support are also important considerations.
Download or read book Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson s Disease written by Christina E. Morrison and published by . This book was released on 2001 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Deep Brain Stimulation for Parkinson s Disease written by Gordon H. Baltuch and published by CRC Press. This book was released on 2007-03-19 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered the largest breakthrough in the treatment of Parkinson's disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's
Download or read book Brain Stimulation written by Günther Deuschl and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation is one of the most effective treatments of Parkinson’s disease (PD). This report summarizes the state of the art as at January 2013. Stimulation of the subthalamic nucleus is the most commonly used approach. It improves the core motor symptoms better than medication in patients with advanced disease. It also improves the majority of nonmotor symptoms, such as mood, impulse control disorders, sleep, and some autonomic dysfunctions. Quality of life (QoL) is improved significantly more than with medication. Long-term data show that the treatment is effective for up to 10 years, but the late appearance of l-dopa-resistant symptoms is seemingly not influenced. Internal globus pallidus (GPi) stimulation is less well studied but seems to have similar short-term efficacy. Importantly l-dopa use cannot be reduced with GPi DBS, which is a major disadvantage for patients suffering from medication side-effects, although gait may be influenced more positively. Although short-term QoL improvement seems to be similar to that for subthalamic nucleus (STN) DBS – gait and speech may be better improved – long-term data are rare for GPi DBS. Thalamic stimulation in the ventral intermediate nucleus (VIM) is applied only in tremor-dominant elderly patients. The treatment improves the dopa-sensitive symptoms and effectively reduces fluctuations leading to an overall QoL improvement. Although most of the controlled studies have been on advanced PD, the recently published EARLYSTIM study suggests that even patients with a very short duration of their fluctuations and dyskinesia are doing significantly better with neurostimulation in terms of QoL and all major motor outcome parameters.
Download or read book Brain Stimulation written by Anna Castrioto and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation has become an established treatment for advanced Parkinson’s disease. Its postoperative management is a delicate phase, dedicated to finding the optimal balance between stimulation and dopaminergic treatment. Postoperative management can be divided into an acute phase, aimed at the selection of the best stimulation contact, and a stabilization phase, aimed at the progressive adjustment of stimulation parameters and medications. A good knowledge of the electrophysiological anatomy of the target and surrounding structures, of the potential consequences of dopaminergic treatment modifications, and of the time course and interactions between stimulation and medication effects is mandatory for optimal outcome. This chapter focuses on the main strategies for the acute and chronic management of stimulation parameters and medication in the three main nuclei targeted in Parkinson’s disease, namely the subthalamic nucleus, the ventral intermediate thalamic nucleus, and the internal part of the globus pallidus.
Download or read book Effects of Deep Brain Stimulation of the Subthalamic Nucleus and the Pedunculopontine Nucleus on Cognitive Function in Parkinson s Disease written by Friederike Leimbach and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Deep Brain Stimulation of the Subthalamic Nucleus and Globus Pallidus Internus for Advanced Parkinson s Disease written by Vincentius Jozef Johannes Odekerken and published by . This book was released on 2016 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Deep Brain Stimulation (DBS) for Parkinson's disease is a treatment option in patients with medication-induced motor response fluctuations, when medication schedule adjustments are no longer able to sustain optimal functioning in daily life. DBS mainly improves motor symptoms that initially responded well to dopaminergic treatment, such as tremor, bradykinesia and rigidity. DBS also reduces the time spent in off-drug phase, dyskinesias, and medication use. The most important complications of surgery are intracerebral hematoma (rarely encountered), infection, hardware complications, and cognitive impairment and behavioral changes. Both globus pallidus parts interna (GPi) DBS and subthalamic nucleus (STN) DBS improve motor symptoms, but it is unclear which nucleus improves symptoms more. Moreover, STN DBS might be associated with more side-effects on cognition, mood, and behavior. The Netherlands SubThalamic And Pallidal Study (NSTAPS) is a randomized controlled trial that compares outcome after GPi DBS and STN DBS up to three years after surgery. Functioning, cognition, mood, behavior, motor symptoms, quality of life and complications of surgery are evaluated. The results are discussed in this thesis. The hypothesis of the study was that GPi DBS and STN DBS give a similar improvement in motor symptoms, but that GPi DBS would result in a better daily functioning due to fewer adverse effects on cognition, mood, and behavior."--Samenvatting auteur.
Download or read book Effects of Deep Brain Stimulation of the Subthalamic Nucleus and the Pedunculopontine Nucleus on Cognitive Function in Parkinson s Disease written by F. M. M. Leimbach and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cognitive Impact of Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson s Disease written by Matthew J. Miller and published by . This book was released on 2005 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation investigated neuropsychological change in the domains of language, executive, attention, and memory based on pre-operative and post-operative assessment of 16 Veteran's Administration patients (15 male, 1 female, mean age = 62.5; age ranges 50-80; mean education = 13.9) diagnosed with Parkinson's disease (PD) who received the procedure of Deep Brain Stimulation (DBS) to the subthalamic nuclei structure (STN). DBS is a relatively new procedure (Benabid, et al. 1991) that employs high frequency stimulation to the STN as an adjunct to Levodopa (L-DOPA) for management of PD motor symptoms for patients whose symptoms have become less responsive to L-DOPA. The impact of DBS on non-motor symptoms has thus far yielded equivocal results. These studies have tended to use small samples and few tests. It was hypothesized that there would be post-operative changes in language, but not in executive, memory, or attention domains. With an alpha leve of .05, results (MANOVA,SPSS 13.0) showed changes only in the language domain (Animal Naming declined, F(1,14) = 8.81, p = .01; Boston Naming improved, F(1, 14) = 6.91, p = .02). Attention, executive, and memory hypotheses were supported. Qualitative review revealed no age effects. Results and implications are discussed.
Download or read book Deep Brain Stimulation Management written by William J. Marks, Jr and published by Cambridge University Press. This book was released on 2015-09-03 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.
Download or read book Brain Stimulation written by Valerie Voon and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation targeting the subthalamic nucleus or globus pallidus internus are highly effective for the symptomatic treatment of Parkinson’s disease. The assessment and management of psychiatric issues is relevant to preoperative patient selection and to optimal postoperative outcomes. This chapter reviews the evidence on psychiatric symptoms in the perioperative state including suicidal behaviors, depression, anxiety, mania, apathy, and impulse control disorders.
Download or read book Trends in Clinical Deep Brain Stimulation written by Marcus L. F. Janssen and published by MDPI. This book was released on 2021-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the current trends in clinical deep brain stimulation (DBS) research. This collection of papers from experts in the field provides state of the art knowledge and future perspectives in clinical DBS research. A range of topics involved in DBS is presented, ranging from high resolution imaging, electrophysiology and personalized medicine, in a broad range of brain disorders.
Download or read book Cognition in Parkinson s Disease written by and published by Elsevier. This book was released on 2022-03-02 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognition in Parkinson's Disease, Volume 269 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Cognition in Prodromal Parkinson’s disease, The epidemiology of cognitive function in Parkinson's disease, Real-life consequences of cognitive dysfunction in Parkinson’s disease, Animal models of cognition in Parkinson’s disease, Functional neuroanatomy of cognition in Parkinson’s disease, Neuroimaging approaches to cognition in Parkinson’s disease, Cognitive dysfunction and neuropsychiatric aspects of Parkinson’s disease, Neuropsychology of Parkinson’s disease, Cholinergic Systems, Attentional-Motor Integration, and Cognitive Control in Parkinson Disease, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research series Updated release includes the latest information on Cognition in Parkinson's Disease
Download or read book Deep Brain Stimulation Think Tank Updates in Neurotechnology and Neuromodulation Research written by Michael S. Okun and published by Frontiers Media SA. This book was released on 2021-12-02 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Explicative Cases of Controversial Issues in Neurosurgery written by Francesco Signorelli and published by IntechOpen. This book was released on 2012-05-23 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosurgery is a rapidly developing field of medicine. Therefore, staying keeping track of the advancements in the field is paramount for trainees as well as fully trained neurosurgeons. This book, fully available online, is a part of our effort of improving availability of medical information for anyone who needs to keep up-to-date.
