Download or read book Drugs written by Rick Ng and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs." —Doody's Reviews, May 2009 "The second edition of a book that offers a user-friendly step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of preclinical trials." —Chemistry World, February 2009 The new edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. This second edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter, Answers to Review Questions provided in a book-end appendix, and one or two carefully selected "mini" case studies in each chapter. Richly illustrated throughout with over ninety figures and tables, this important book also includes helpful listings of current FDA and European guidelines and a special section on regulatory authority and processes in China. It is an indispensable resource for pharmaceutical industry and academic researchers, pharmaceutical managers and executives, healthcare clinicians, policymakers, regulators, and lobbyists with an interest in drug development. It is also an excellent textbook for students in pharmacy, science, and medicine courses.

Download or read book Obtaining Discovery Abroad written by and published by American Bar Association. This book was released on 2005 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newly-revised and expanded edition of Obtaining Discovery Abroad assists those involved in U.S. litigation in understanding the legal and practical steps for bringing evidence from a foreign jurisdiction back to the United States.

Download or read book Drug Discovery and Development Third Edition written by James J. O'Donnell and published by CRC Press. This book was released on 2019-12-13 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business

Download or read book Drug Discovery and Development E Book written by Raymond G Hill and published by Elsevier Health Sciences. This book was released on 2012-07-20 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from its origins in the mediaeval apothecaries' trade, and discusses the changing understanding of what we mean by disease, and what therapy aims to achieve, as well as summarising case histories of the discovery and development of some important drugs. The second part focuses on the science and technology involved in the discovery process: the stages by which a promising new chemical entity is identified, from the starting point of a medical need and an idea for addressing it. A chapter on biopharmaceuticals, whose discovery and development tend to follow routes somewhat different from synthetic compounds, is included here, as well as accounts of patent issues that arise in the discovery phase, and a chapter on research management in this environment. The third section of the book deals with drug development: the work that has to be undertaken to turn the drug candidate that emerges from the discovery process into a product on the market. - The definitive introduction to how a pharmaceutical company goes about its business of discovering and developing drugs. The second edition has a new editor: Professor Raymond Hill ● non-executive director of Addex Pharmaceuticals, Covagen and of Orexo AB ● Visiting Industrial Professor of Pharmacology in the University of Bristol ● Visiting Professor in the School of Medical and Health Sciences at the University of Surrey ● Visiting Professor in Physiology and Pharmacology at the University of Strathclyde ● President and Chair of the Council of the British Pharmacological Society ● member of the Nuffield Council on Bioethics and the Advisory Council on Misuse of Drugs. New to this edition: - Completely rewritten chapter on The Role of Medicinal Chemistry in the Drug Discovery Process. - New topic - DMPK Optimization Strategy in drug discovery. - New chapter on Scaffolds: Small globular proteins as antibody substitutes. - Totally updated chapters on Intellectual Property and Marketing - 50 new illustrations in full colour Features - Accessible, general guide to pharmaceutical research and development. - Examines the interfaces between cost and social benefit, quality control and mass production, regulatory bodies, patent management, and all interdisciplinary intersections essential to effective drug development. - Written by a strong team of scientists with long experience in the pharmaceutical industry. - Solid overview of all the steps from lab bench to market in an easy-to-understand way which will be accessible to non-specialists. From customer reviews of the previous edition: '... it will have everything you need to know on this module. Deeply referenced and, thus, deeply reliable. - Highly Commended in the medicine category of the BMA 2006 medical book competition - Winner of the Royal Society of Medicine Library Prize for Medical Book of the Year

Download or read book Electronic Discovery and Digital Evidence written by Shira Ann Scheindlin and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound - New, hardbound print book.

Download or read book Joint Ventures written by and published by American Bar Association. This book was released on 2006 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joint Ventures: Antitrust Analysis of Collaborations Among Competitors is the first book to provide a comprehensive analysis of antitrust joint venture law in the immediate aftermath of the Supreme Court's landmark Dagher decision. It reviews antitrust principles applicable to joint ventures and other competitor collaborations, taking into account relevant statutory and case law as well as government guidelines and enforcement practices.

Download or read book World Religions written by Jeffrey Brodd and published by Saint Mary's Press. This book was released on 2003 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major religions of the world are a mystery to many high school teens. Now you can help them unlock the doors of these traditions with our new text, World Religions: A Voyage of Discovery. The book is an introductory survey that helps eleventh and twelfth graders understand the people, dimensions, and religious principles of the world's major religions. The textbook includes a chapter on each of eleven major world religions, including Christianity, Islam, Hinduism, Buddhism, Judaism, and others. The text offers the Catholic perspective on interreligious dialogue, an overview of basic questions that religions address, and Ninian Smart's seven dimensions of religion. A glossary and word pronunciations in each chapter help students learn unfamiliar terms. In addition, the second edition of this text incorporates the following new features: a new chapter on modern trends in religion; new, more detailed maps; a new section on the Aztec religion of Mesoamerica; a sidebar in each chapter offering examples of the seven dimensions of religion; and review questions at the end of each chapter.

Download or read book The World of All Souls written by Deborah Harkness and published by Penguin. This book was released on 2018-05-08 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the author of The Black Bird Oracle comes a fully illustrated guide to the #1 New York Times bestselling All Souls series—“an irresistible . . . wonderfully imaginative grown-up fantasy” (People). Look for the hit series “A Discovery of Witches,” now streaming on AMC+, Sundance Now, and Shudder! A world of witches, vampires, and daemons. A manuscript that holds the secrets of their past and the key to their future. Diana and Matthew—the forbidden love at the heart of the adventure. In The World of All Souls, Deborah Harkness shares the rich sources of inspiration behind her bewitching novels. She draws together synopses, character bios, maps, recipes, and even the science behind creatures, magic, and alchemy—all with her signature historian's touch. Bursting with fascinating facts and dazzling artwork, this essential handbook is a must-have for longtime fans and eager newcomers alike.

Download or read book The Sedona Principles written by Jonathan M. Redgrave and published by Pike & Fischer - A BNA Company. This book was released on 2007 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nmap Network Exploration and Security Auditing Cookbook written by Paulino Calderon and published by Packt Publishing Ltd. This book was released on 2021-09-13 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete reference guide to mastering Nmap and its scripting engine, covering practical tasks for IT personnel, security engineers, system administrators, and application security enthusiasts Key FeaturesLearn how to use Nmap and other tools from the Nmap family with the help of practical recipesDiscover the latest and most powerful features of Nmap and the Nmap Scripting EngineExplore common security checks for applications, Microsoft Windows environments, SCADA, and mainframesBook Description Nmap is one of the most powerful tools for network discovery and security auditing used by millions of IT professionals, from system administrators to cybersecurity specialists. This third edition of the Nmap: Network Exploration and Security Auditing Cookbook introduces Nmap and its family - Ncat, Ncrack, Ndiff, Zenmap, and the Nmap Scripting Engine (NSE) - and guides you through numerous tasks that are relevant to security engineers in today's technology ecosystems. The book discusses some of the most common and useful tasks for scanning hosts, networks, applications, mainframes, Unix and Windows environments, and ICS/SCADA systems. Advanced Nmap users can benefit from this book by exploring the hidden functionalities within Nmap and its scripts as well as advanced workflows and configurations to fine-tune their scans. Seasoned users will find new applications and third-party tools that can help them manage scans and even start developing their own NSE scripts. Practical examples featured in a cookbook format make this book perfect for quickly remembering Nmap options, scripts and arguments, and more. By the end of this Nmap book, you will be able to successfully scan numerous hosts, exploit vulnerable areas, and gather valuable information. What you will learnScan systems and check for the most common vulnerabilitiesExplore the most popular network protocolsExtend existing scripts and write your own scripts and librariesIdentify and scan critical ICS/SCADA systemsDetect misconfigurations in web servers, databases, and mail serversUnderstand how to identify common weaknesses in Windows environmentsOptimize the performance and improve results of scansWho this book is for This Nmap cookbook is for IT personnel, security engineers, system administrators, application security enthusiasts, or anyone who wants to master Nmap and its scripting engine. This book is also recommended for anyone looking to learn about network security auditing, especially if they're interested in understanding common protocols and applications in modern systems. Advanced and seasoned Nmap users will also benefit by learning about new features, workflows, and tools. Basic knowledge of networking, Linux, and security concepts is required before taking up this book.

Download or read book The Hope of Spring written by Wanda E. Brunstetter and published by Barbour Publishing. This book was released on 2013-04-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book 3 of an exclusive 6-consecutive-month release Amish serial novel. In The Hope of Spring, part three of New York Times Bestselling author, Wanda E. Brunsetter’s The Discovery--A Lancaster County Saga, Meredith Stoltzfus is trying to piece her life back together, while in a hospital miles away, a young man is fighting for his life and remains in a coma. . . . Weeks away from the baby being born, Meredith has never been so scared. She aches for Luke and knows her baby will need his father. She’s nearly out of money; can she somehow manage to provide for herself and her baby—alone? The Discovery--A Lancaster County Saga Book 1 - Goodbye to Yesterday Book 2 - The Silence of Winter Book 3 - The Hope of Spring Book 4 - The Pieces of Summer Book 5 - A Revelation in Autumn Book 6 - A Vow for Always

Download or read book Textbook of Drug Design and Discovery Third Edition written by Tommy Liljefors and published by CRC Press. This book was released on 2002-07-25 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

Download or read book Africa s Discovery of Europe written by David Northrup and published by Oxford University Press, USA. This book was released on 2009 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Examines the full range of African-European encounters from an unfamiliar African perspective rather than from the customary European one"--Publisher description.

Download or read book Discovering the Scientist Within written by Gary Lewandowski and published by Worth. This book was released on 2019-02-07 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovering the Scientist Within is the only book on the market that teaches students about research methods using a case study approach. All the design-focused chapters present students with a single study described from start to finish. Chapters start by asking students to consider a scenario and then walks them through the steps of the study: formulating a research question, performing a literature review, constructing a data collection method, considering ethics, refining the method, gathering data, understanding and reporting the statistical results. Students come away with a practical understanding of the research process and useful practice in the basic steps that comprise all studies. The book can also be purchased with the breakthrough online resource, LaunchPad, which offers innovative media content, curated and organised for easy assignability. LaunchPad's intuitive interface presents quizzing, flashcards, animations and much more to make learning actively engaging.

Download or read book Encyclopedia of Information Science and Technology Third Edition written by Khosrow-Pour, Mehdi and published by IGI Global. This book was released on 2014-07-31 with total page 7972 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This 10-volume compilation of authoritative, research-based articles contributed by thousands of researchers and experts from all over the world emphasized modern issues and the presentation of potential opportunities, prospective solutions, and future directions in the field of information science and technology"--Provided by publisher.

Download or read book Teaching Science Through Discovery written by Arthur A. Carin and published by Merrill Publishing Company. This book was released on 1989 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Human Osteology written by Tim D. White and published by Gulf Professional Publishing. This book was released on 2000 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction. Bone Biology. Anatomical Terminology. Skull. Dentition. Hyoid and Vertebrae. Thorax: Sternum and Ribs. Shoulder Girdle: Clavicle and Scapula. Arm: Humerus, Radius, Ulna. Hand: Carpals, Metacarpals, and Phalanges. Pelvic Girdle: Sacrum, Coccyx, and Os Coxae. Leg: Femur, Patella, Tibia, and Fibula. Foot: Tarsals, Metatarsals, and Phalanges. Recovery, Preparation, and Curation of Skeletal Remains. Analysis and Reporting of Skeletal Remains. Ethics in Osteology. Assessment of Age, Sex, Stature, Ancestry, and Identity. Osteological and Dental Pathology. Postmortem Skeletal Modification. The Biology of Skeletal Populations: Discrete Traits, Distance, Diet, Disease, and Demography. Molecular Osteology. Forensic Case Study: Homicide: "We Have the Witnesses but No Body." Forensic Case Study: Child Abuse, The Skeletal Perspective. Archaeological Case Study: Anasazi Remains from Cottonwood Canyon. Paleontological Case Study: The Pit of the Bones. Paleontological Case Study: Australopitheus Mandible from Maka, Ethiopia. Appendix: Photographic Methods and Provenance. Glossary. Bibliography. Index.