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Book Practical Aspects of Ion Trap Mass Spectrometry

Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-09-18 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.

Book The Use of an Ion Trap Storage reflectron Time of flight Mass Spectrometer as a Rapid and Sensitive Mass and Tandem Mass Detector for Capillary Separations

Download or read book The Use of an Ion Trap Storage reflectron Time of flight Mass Spectrometer as a Rapid and Sensitive Mass and Tandem Mass Detector for Capillary Separations written by Jingtao Wu and published by . This book was released on 1997 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Practical Aspects of Trapped Ion Mass Spectrometry

Download or read book Practical Aspects of Trapped Ion Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 2010-05-25 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapping ions, such as the OrbitrapTM, the digital ion trap (DIT), the rectilinear ion trap (RIT), and the toroidal ion trap; the development and application of the quadrupole ion trap (QIT) and the quadrupole linear ion trap (LIT); and the introduction of high-field asymmetric waveform ion mobility spectrometry (FAIMS). After a combined appreciation and historical survey of mass spectrometry and a discussion of how improved capabilities for microfabrication have led to interest in arrays of ion traps, the book examines the theory and practice of the Orbitrap mass analyzer, the rectangular waveform-driven DIT mass spectrometer, FAIMS, and ion traps with circular geometries. It next discusses ion accumulation for increasing sensitivity in FT-ICR spectrometry, a radio frequency-only-mode event for Penning traps in FT MS, and an FT operating mode applied to a 3D-QIT. The text then presents three behavioral aspects of quadrupole rod sets, before illustrating the development of the 3D-QIT in recent years. The final chapters explore photodissociation in ion traps and the chemical and photochemical studies of metal dication complexes in a 3D-QIT. In this volume that spans twenty-one chapters, a stellar panel of leading experts and up-and-coming researchers presents a cohesive, global, and up-to-date view of the practical aspects of using trapped ion devices. A companion to Volume V: Applications of Ion Trapping Devices, the book authoritatively covers the theory involved as well as the instrumentation currently used in this dynamic field.

Book Practical Aspects of Ion Trap Mass Spectrometry

Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC-Press. This book was released on 1995-09-18 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.

Book Development of a Quadrupole Ion Trap

Download or read book Development of a Quadrupole Ion Trap written by Beni B. Dangi and published by . This book was released on 2011 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of a tandem mass spectrometer, consisting of a quadrupole ion trap (QIT) and a time-of-flight, is described for ion mass resolution and photophysics. Ions are generated externally by electrospray ionization and trapped in the quadrupole ion trap before extraction to the time-of-flight section for mass analysis. The non-parallel fields in the hyperbolic ion trap, which serves as the first acceleration region in the time-of-flight mass spectrometer, are shown to degrade spatial focusing and mass resolution. A novel short-pulse ion extraction method is shown to be useful in diagnosis of the trapped ion cloud size, energy and dispersal time. New ion trap geometries are evaluated theoretically for improvement in mass resolution as well as ion photophysics with similar ion trapping behavior compared with the existing hyperbolic ion trap. Parameters affecting mass resolutions in linear and reflectron time-of-flight modes are identified and possible improvements are discussed. An ion trap consisting of two endcaps and two ring flat electrodes is proposed and constructed on this basis. The newly optimized design is shown to yield the mass resolution of several thousand even at room temperature with moderate extraction field. Significant improvements in ion-laser interaction and photon collection are shown in the optimized design compared to the existing hyperbolic QIT. A molecular beam source is designed, fabricated and characterized for the application in ion-molecule collision experiments. Ionization methods, from solution to gas-phase, of small polycyclic aromatic hydrocarbons are developed and compared. A photo ionization source was designed and constructed to interface in the current mass spectrometer with fast switching capability with the current electrospray source.

Book Theoretical and Experimental Improvements for Using an Ion Trap reflectron Time of flight Mass Spectrometer to Detect Biological Molecules

Download or read book Theoretical and Experimental Improvements for Using an Ion Trap reflectron Time of flight Mass Spectrometer to Detect Biological Molecules written by Ling He and published by . This book was released on 1997 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Mass Spectrometry

    Book Details:
  • Author : Jürgen H Gross
  • Publisher : Springer Science & Business Media
  • Release : 2006-04-05
  • ISBN : 3540407391
  • Pages : 534 pages

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Book Mass Spectrometry in Polymer Chemistry

Download or read book Mass Spectrometry in Polymer Chemistry written by Christopher Barner-Kowollik and published by John Wiley & Sons. This book was released on 2012-01-27 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining an up-to-date insight into mass-spectrometric polymer analysis beyond MALDI with application details of the instrumentation, this is a balanced and thorough presentation of the most important and widely used mass-spectrometric methods. Written by the world's most proficient experts in the field, the book focuses on the latest developments, covering such technologies and applications as ionization protocols, tandem and liquid chromatography mass spectrometry, gas-phase ion-separation techniques and automated data processing. Chapters on sample preparation, polymer degradation and the usage of mass-spectrometric tools on an industrial scale round off the book. As a result, both entrants to the field and experienced researchers are able to choose the appropriate methods and instrumentations -- and to assess their respective strengths and limitations -- for the characterization of polymer compounds.

Book Development of a Quadrupole Ion Trap Mass Spectrometer

Download or read book Development of a Quadrupole Ion Trap Mass Spectrometer written by Joseph Ellis Hebert and published by . This book was released on 2000 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Analyzing Biomolecular Interactions by Mass Spectrometry

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Book Practical Aspects of Trapped Ion Mass Spectrometry  Volume IV

Download or read book Practical Aspects of Trapped Ion Mass Spectrometry Volume IV written by Raymond E. March and published by CRC Press. This book was released on 2010-05-25 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapp

Book Spectroscopy and Modeling of Biomolecular Building Blocks

Download or read book Spectroscopy and Modeling of Biomolecular Building Blocks written by Jean-Pierre Schermann and published by Elsevier. This book was released on 2007-10-16 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy and Modeling of Biomolecular Building Blocks presents an overview of recent advances in the intertwining of the following research fields: photon and electron spectroscopy, quantum chemistry, modelling and mass-spectrometry. The coupling of these disciplines offers a new point of view to the understanding of isolated elementary building blocks of biomolecules and their assemblies. It allows the unambiguous separation between intrinsic properties of biomolecular systems and those induced by the presence of their environment. The first chapters provide background in modelling (I), frequency-resolved spectroscopy using microwave, infrared and UV photons, time-resolved spectroscopy in the femtosecond domain and energy-resolved electron spectroscopy (II) and production of gas-phase neutral and ionic biomolecular species, mass-spectrometry, ion mobility and BIRD techniques (III). Chapter IV is devoted to case studies of gas-phase experimental investigations coupled to quantum or classical calculations. The topics are structural studies of nucleobases and oligonucleotides, peptides and proteins, sugars; neuromolecules; non-covalent complexes; chiral systems, interactions of low-energy electrons with biomolecules in the radiation chemistry context and very large gas-phase biomolecular systems. The fifth chapter concerns the link between gas-phase and liquid-phase. Different treatments of solvation are illustrated through examples pointing out the influence of progressive addition of water molecules upon properties of nucleobases, peptides, sugars and neuromolecules. - Offer a new perspective to the understanding of isolated elementary building blocks of bio molecules - Includes case studies of experimental investigations coupled to quantum or classical calculations