Download or read book Chirality in Drug Design and Development written by Indra K. Reddy and published by CRC Press. This book was released on 2004-03-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.

Download or read book Dynamic Stereochemistry of Chiral Compounds written by Christian Wolf and published by Royal Society of Chemistry. This book was released on 2008 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.

Download or read book Introduction to Stereochemistry written by Torsten Schmiermund and published by Springer Nature. This book was released on 2021-06-07 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conformal, diastereomers, rotamers, tautomers, anomers: The multitude of terms used in stereochemistry quickly makes this subfield of chemistry confusing. In addition, there are different nomenclatures and different forms of representation (Fischer projection, Haworth ring formula, Newman projection). This essential deals with basic static stereochemistry and gives an overview of the different isomeric forms and nomenclatures. It is thus both a help and a reference book. This Springer essential is a translation of the original German 1st edition essentials, Einführung in die Stereochemie by Torsten Schmiermund, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2019. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.

Download or read book Choice written by and published by . This book was released on 1997 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stereochemical Aspects of Drug Action and Disposition written by Michel F. Eichelbaum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to guide and inspire drug researchers as they enter the 21st century. Stereochemistry is an essential dimension in pharmacology and should be understood as such by all drug researchers whatever their background. When used as probes or medicines, stereoisomeric drugs offer invaluable insights or innovative therapeutic strategies. The book spans the subject from the molecular to the clinical. The first section on chemical aspects contains chapters on chemical synthesis, analysis, natural products, chiral stability (racemezation) and physical properties. The second section is on experimental pharmacology, with chapters on drug-receptor interactions, chiral recognition, ion channels, and molecular toxicology. The third section focuses on drug disposition, with chapters on absorption, distribution, protein binding, metabolism and elimination. The final section is dedicated to regulatory and clinical aspects.

Download or read book The Johnstone Triangle written by Norman Reid and published by Royal Society of Chemistry. This book was released on 2021-01-29 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry is often seen as a difficult subject to understand. This book focusses on the triangle model that Alex H. Johnstone developed in the early 1980s. The model has been applied in almost every area of education in chemistry at all stages of learning.

Download or read book Vibrational Optical Activity written by Laurence A. Nafie and published by John Wiley & Sons. This book was released on 2011-07-12 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book stands as the only comprehensive introduction to vibrational optical activity (VOA) and is the first single book that serves as a complete reference for this relatively new, but increasingly important area of molecular spectroscopy. Key features: A single-source reference on this topic that introduces, describes the background and foundation of this area of spectroscopy. Serves as a guide on how to use it to carry out applications with relevant problem solving. Depth and breadth of the subject is presented in a logical, complete and progressive fashion. Although intended as an introductory text, this book provides in depth coverage of this topic relevant to both students and professionals by taking the reader from basic theory through to practical and instrumental approaches.

Download or read book Stereochemistry of Organic Compounds written by Ernest L. Eliel and published by John Wiley & Sons. This book was released on 1994-09-28 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereochemistry of Organic Compounds The first fully referenced, comprehensive book on this subject in more than thirty years, Stereochemistry of Organic Compounds contains up-to-date coverage and insightful exposition of all important new concepts, developments, and tools in the rapidly advancing field of stereochemistry, including: * Asymmetric and diastereoselective synthesis * Conformational analysis * Properties of enantiomers and racemates * Separation and analysis of enantiomers and diastereoisomers * Developments in spectroscopy (including NMR), chromatography, and molecular mechanics as applied to stereochemistry * Prostereoisomerism * Conceptual foundations of stereochemistry, including terminology and symmetry concepts * Chiroptical properties Written by the leading authorities in the field, the text includes more than 4,000 references, 1,000 illustrations, and a glossary of stereochemical terms.

Download or read book Memorial Issue Dedicated to Dr Howard D Flack The Man Behind the Flack Parameter written by Katharina M. Fromm and published by . This book was released on 2021 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is dedicated to the work and achievements of Howard Flack. It combines articles which describe his own work and the advances he made in the field of crystallography, with original research articles which focus on aspects related to Howard Flack's interests.

Download or read book Drug Discovery and Development written by Ramarao Poduri and published by Springer Nature. This book was released on 2021-02-15 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Download or read book Choice written by Richard K. Gardner and published by . This book was released on 1976 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemistry The Impure Science 2nd Edition written by Jonathan Simon and published by World Scientific. This book was released on 2012-06-26 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: What do you associate with chemistry? Explosions, innovative materials, plastics, pollution? The public's confused and contradictory conception of chemistry as basic science, industrial producer and polluter contributes to what we present in this book as chemistry's image as an impure science. Historically, chemistry has always been viewed as impure both in terms of its academic status and its role in transforming modern society. While exploring the history of this science we argue for a characteristic philosophical approach that distinguishes chemistry from physics. This reflection leads us to a philosophical stance that we characterise as operational realism. In this new expanded edition we delve deeper into the questions of properties and potentials that are so important for this philosophy that is based on the manipulation of matter rather than the construction of theories./a

Download or read book The Organic Chemistry of Sugars written by Daniel E. Levy and published by CRC Press. This book was released on 2005-09-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst

Download or read book Mixture and Chemical Combination written by Pierre Duhem and published by Springer Science & Business Media. This book was released on 2002-01-31 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to lecturing in physics, Duhem began to publish articles on philosophical and historical topics related to his scientific interests in the late 19th century, many of which appeared in the Catholic journal Revue des questions scientifiques. The present volume focuses on chemistry, and includes the book, Le mixte et la combinaison chimique (1902), as well as several related articles from Revue des questions scientifiques and other sources, appearing here in English translation for the first time. Translated by Paul Needham (U. of Stockholm). For Duhem scholars, philosophers of science and chemists with an interest in philosophy. Annotation copyrighted by Book News, Inc., Portland, OR.

Download or read book Dietary Reference Intakes for Vitamin A Vitamin K Arsenic Boron Chromium Copper Iodine Iron Manganese Molybdenum Nickel Silicon Vanadium and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Download or read book Guide to Technology Databases written by World Intellectual Property Organization and published by WIPO. This book was released on 2002 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present Guide is a detailed technical paper aimed at industrial property office examiners and users in general to assist them in identifying the correct database and using the possible functionalities and tools offered by specific databases. The current Guide examines a selection of commercial and non-commercial database services considered representative of the broader population of existing services in order to illustrate types and combinations of features available through these services.

Download or read book Green Chemistry Education written by Paul T. Anastas and published by . This book was released on 2009 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Chemistry has brought about dramatic changes in the teaching of chemistry that have resulted in increased student excitement for the subject of chemistry, new lecture materials, new laboratory experiments, and a world-wide community of Green Chemistry teachers. This book features the cutting edge of this advance in the teaching of chemistry.