Download or read book Proceedings of the Conference on the Decline in Coronary Heart Disease Mortality written by and published by . This book was released on 1979 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Data on the decrease in coronary heart disease in the US are presented in a collection of papers. Change, and trends in the US are compared to international trends (based on mortality and hospital data). Possible causes for the decline, including pathophysiological bases, coronary care, and artery bypass grafts are covered. Finally, changes in risk factors are described: trends in smoking and hypertension; food consumption patterns; changes in blood cholesterol; relation of physical activity, and environmental and social variables. A summary strategy for quantifying and studying coronary heart disease change is included. (rkm).

Download or read book The Decline in Coronary Heart Disease Mortality the Role of Cholesterol Change written by Robert I. Levy and published by . This book was released on 1983 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cholesterol Lowering in the Patient with Coronary Heart Disease written by and published by . This book was released on 1997 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Decline in Coronary Heart Disease Mortality written by Robert I. Levy and published by . This book was released on 1984 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-26 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Download or read book A Better Understanding of Recent Coronary Heart Disease Mortality Trends and Determinants written by Martin O'Flaherty and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction Coronary heart disease (CHD) is one of the leading global causes of morbidity and mortality. The underlying biological mechanisms are well understood, and a host of causal risk factors for the disease have been identified, mainly related to diet, smoking and physical activity. Evidence-based treatments for the disease are also available, reducing mortality and improving quality of life. The decline in CHD mortality rates observed in most developed countries since the 1960s represents a most remarkable epidemiological phenomenon. However, this decline is not universal, and may now be in jeopardy. Thus, the mortality decline has recently plateaued in young adults in the United States. Furthermore, the absolute burden of disease is set to increase mainly because of an increasingly ageing population, and will represent a heavy burden to high, middle and low income countries alike. Furthermore, CHD incidence may rise in future because of recent adverse trends in major CHD risk factors, namely the worldwide increases in obesity and diabetes prevalence observed since the 1980s. Moreover, new technology and improved treatments are decreasing case fatality in CHD patients, increasing life expectancy and thus expanding the pool of patients surviving with clinically apparent disease. Finally, and crucially, important socioeconomic inequalities persist, perhaps reflecting disease determinants. The complex interplay of these factors and potential changes over time together suggest that the CHD epidemic may still be evolving. Further attention is therefore essential. The analysis of time trends in disease specific mortality can thus potentially help us to understand the population dynamic of diseases such as CHD, warn about key changes and perhaps offer some novel insights for better prevention and control. However, most previous analyses have been focused on age-adjusted rates that might conceal important differences by age or by socioeconomic status, which might provide further understanding of trend drivers. Aims and objectives: My aim is to study recent coronary heart disease mortality time trends in different countries, in order to better understand the current state of the CHD epidemic. Furthermore, I will analyze the relative importance of CHD treatments and risk factors as drivers of the mortality trends. Finally, I will consider the Public Health implications of my findings. My objectives therefore are: 1. To summarize our current understanding of Coronary Heart Disease (CHD) causation 2. To describe recent CHD mortality time trends focusing on age and gender specific trends by identifying periods with similar rate of change in diverse populations (England & Wales, the Netherlands, Poland and Australia). 3. To describe recent CHD mortality time trends by Socio-Economic Status in England and Scotland. 4. To quantify the role of risk factors and evidence-based treatments as drivers of the CHD mortality trends, first using a modelling approach in Poland, and then in England while also considering socioeconomic factors. 5. To consider the public health policy implications of dynamic trends in coronary heart disease mortality. Methods CHD mortality trends were analysed using the joinpoint regression approach. Widely used in cancer epidemiology, but rarely in CHD, this method explores trend data to find points in time ("joinpoints") that define segments where the trend has a constant pace of change. The key strength of this technique is objectivity- (it avoids the detection of potentially biased patterns when trends are described using time intervals defined subjectively by the researcher). Joinpoint avoids this potential bias by essentially removing the observer from the selection process, instead using a formal and objective exploration of the time-series data. My analysis therefore focused on age-adjusted rates, then age and gender specific rates. The analysis for Scotland and England also considered socio-economic status (using area-based measures of material deprivation). The contributions of risk factors and treatments to the observed CHJD mortality trends in Poland were studied using the IMPACT model, a comprehensive, population-based model of CHD epidemiology. The model goal is to quantify the decline in coronary heart disease deaths in the Polish population between 1991 and 2005 which might be explained by risk factor changes and by treatments. The model is comprehensive, incorporating all usual treatments for coronary heart disease and heart failure plus all major cardiovascular risk factors, including smoking, blood pressure, cholesterol, diabetes, obesity and physical activity. Similar analyses but also exploring the socio-economic differences were conducted in England, using a modified IMPACT model (IMPACTsec). That was used to estimate the contribution of risk factors and evidence based treatments to the observed decline in mortality in England between 2000 and 2007, for each quintile of the index of multiple deprivation. Results Age-adjusted trends in England and Wales, Scotland, Australia and the Netherlands conceal important recent age specific patterns. In these countries, the age-adjusted rates show continuing declines; however, among young adults a recent period of slowing down of the rate of decline in CHD mortality has been observed. Furthermore, trends are very dynamic, and the patterns can change surprisingly quickly. In the Netherlands, the sustained period of minimal change in young adults was followed by a period of further decline. Poland offers a strikingly different example of trend dynamism. After a period of constant increase, Poland showed a sudden, sharp decline in CHD mortality rates within a period of a very few years. This decline occurred in all age and gender groups, and still continues. The recent mortality trends are probably attributable more to changes in risk factors rather than medical treatments. For example, using the IMPACT model to study the decline phase of the Polish CHD epidemic, approximately 55% of the observed fall in mortality might be attributed to changes in risk factors, and only about a third to evidence based therapies. Because of the social patterning of risk factors levels, further insights on the role of risk factors as major contributors to trend changes can be obtained by studying trends in levels stratified by socioeconomic circumstances. Scotland and England offer particular opportunities for detailed studies of trends in CHD mortality using high quality data including socioeconomic status. The resulting picture is complex. The recent flattening in CHD mortality trends observed in young adults was confined to the most deprived groups in Scotland, but was more uniform in England. A marked deterioration of medical care is implausible, meaning that the most likely explanation for this recent flattening of CHD mortality must be adverse trends in major cardiovascular risk factors. The CHD mortality modelling in England produced intriguing results. As expected, socio-economic patterning of risk factor changes were observed. For example, decline in smoking levels contributed more to the observed decline amongst the more deprived groups. Social patterning was less clear among young adults in England. Moreover, the IMPACT SEC model analysis suggested that approximately half the CHD mortality fall was attributable to improved treatment uptake, with benefits occurring surprisingly equitably across all social groups. A similar analysis of the Scottish trends is therefore urgently needed to gain better insights on the drivers of the socioeconomic patterning underlying the observed trends. Conclusions The recent flattening in CHD mortality in young adults seen in many countries experiencing an overall decline in deaths strongly suggests that favourable trends can reverse.

Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Decline in Coronary Heart Disease Mortality written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report of the Expert Panel on Population Strategies for Blood Cholesterol Reduction written by National Cholesterol Education Program (U.S.). Expert Panel on Population Strategies for Blood Cholesterol Reduction and published by . This book was released on 1990 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication contains the report of the panel on its findings and recommendations regarding blood cholesterol reduction. Recommendations include: intake of less than 10 percent of total calories from saturated fatty acids; intake of an average of 30 percent, or less, of total calories from all fat; dietary energy levels needed to reach or maintain a desirable body weight; and less than 300 mg. of cholesterol per day. The panel makes recommendations for various groups to become involved with general population strategies.

Download or read book Status and Perspectives on the Role of Cholesterol written by American College of Cardiology and published by . This book was released on 1984 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cholesterol and Beyond written by A. Stewart Truswell and published by Springer Science & Business Media. This book was released on 2010-06-22 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Only once in a great while does a book come along that really does the job in addressing a major medical issue. When this happens, all can be joyful... Readers will find ALL their favorite dietary puzzlements dealt with... With consummate scholarship, clarity and brevity, Truswell sifts out the chaff and identifies the critical questions, the responsible investigators, and the key studies.” So says Emeritus Professor Henry Blackburn from the University of Minnesota in the foreword to this remarkable concise book on the history of research on diet and heart disease. This was a theme of scientific, medical and public interest in the 20th Century, a century marked by the rise and fall of coronary heart disease as the major cause of death in the first world, followed by the rise of this cause of death in the developing world. There is obviously much to learn, and this book is an excellent starting point, tracing dietary factors and their role in heart disease one by one: fats, sugar, salt, alcohol, coffee, trans-fats, etc. Without an understanding of the role of diet and the changes that have been seen in the North American and NW European diet, the story of the decline in the heart disease death rate may have been very different.

Download or read book Prevention of Coronary Heart Disease written by Ira S. Ockene and published by Little, Brown Medical Division. This book was released on 1992 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cardiovascular Diseases in the United States written by Iwao Milton Moriyama and published by Harvard University Press. This book was released on 1971 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases kill and disable more than a million Americans each year. The major types of this complex of diseases are coronary heart disease, hypertensive disease, cerebrovascular diseases, rheumatic heart disease, and congenital malformations of the circulatory system. Authors Moriyama, Krueger, and Stamler relate each of these types to etiology, age of patient at onset, clinical course, and socioeconomic impact on the population. For each type of cardiovascular disease they analyze the quantitative data on the incidence, prevalence, and levels and time trends of mortality and on the demographic characteristics of person affected. They also examine international differences in levels and trends in mortality and point out areas for further research. More than thirty-five figures as well as extensive tables document their text.

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Download or read book High and Rising Mortality Rates Among Working Age Adults written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-12-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The decline in coronary heart disease mortality written by and published by . This book was released on 1984 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Cholesterol Controversy written by Gilbert R. Thompson and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cholesterol Controversy recounts the long-running debate surrounding the relationship between cholesterol and coronary heart disease. Focusing primarily on events in the UK and the personalities involved, the story is unraveled here, from the origins of the controversy in the 1950s, to the discovery, development and trials of statins in the 1970s, 80s and 90s, culminating with recent concerns over the efficacy of ezetimibe and safety of torcetrapib.