Download or read book The Crystal Structure of YaaE from Bacillus Subtilis and a Model for YaaE Interactions with YaaD written by Jacob Arthur Bauer and published by . This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2005 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Directory of Graduate Research written by American Chemical Society. Committee on Professional Training and published by . This book was released on 2005 with total page 1932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Download or read book On the Structure and Function of Succinate quinone Oxidoreductase Using Bacillus Subtilis as Model Organism written by Cecilia Hägerhäll and published by . This book was released on 1994 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacillus Subtilis and Human Adenylosuccinate Lyase written by Sharmila Sivendran and published by ProQuest. This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenylosuccinate lyase is a homotetrameric enzyme that catalyzes two reversible reactions in the purine biosynthetic pathway. ASL deficiency results from several single point mutations which result in mild to severe mental retardation, muscle wasting and autistic features. Two novel point mutations, E80D and D87E, identified in an Australian patient, were characterized. Although one of the point mutations, E80D, is far from the active site, it seems to have a more detrimental effect on enzyme function as compared to D69E, which is found close to the active site. Mutagenesis studies of conserved residues in the active site have suggested that p K 2 of the pH-V max profile reflects the ionization of histidines. Conserved residues close to His 68 in the crystal structure, Asp 69 and Arg 310, when analyzed by mutagenesis, show that replacement of these charged residues with neutral residues results in greatly decreased activity, suggesting these residues are important for catalytic activity. When the same charge is maintained there is little change in p K 2 (indicating the His 68 proton is held tightly, as in WT), but when the charge is removed there is a decrease in p K 2 suggesting the His 68 proton is removed more easily. This shift in p K 2 supports the previous postulate that His 68 acts as the general acid. ASL catalyzes two similar reactions, questioning whether the two substrates occupy the same or different active sites. Studies with a new substrate analogue, adenosine phosphonobutyric acid, 2'(3'), 5'-diphosphate, show the two substrates occupy the same active site. Binding studies with this substrate analogue demonstrate that B. subtilis ASL has negative and human ASL has positive cooperativity in binding ligand. Binding studies of B. subtilis ASL inactive mutants show that these mutants bind the substrate analogue similarly to WT, indicating the replaced amino acids are important for catalysis (k cat) and not for binding substrate. Serines in the signature sequence region of the fumarase superfamily of enzymes, when mutated to determine the effect of these residues on activity, show that human Ser 289, B. subtilis Ser 262 and Ser 263 affect V max but not binding and that they may be interacting with the active sites.
Download or read book Biosynthesis of vitamins in plants Part B Vitamins B6 B8 B9 C E K written by Fabrice Rébeillé and published by Academic Press. This book was released on 2011 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Duty and Desire Book Club Edition written by Anju Gattani and published by . This book was released on 2021-01-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: To uphold family honor and tradition, Sheetal Prasad is forced to forsake the man she loves and marry playboy millionaire Rakesh Dhanraj while the citizens of Raigun, India, watch in envy. On her wedding night, however, Sheetal quickly learns that the stranger she married is as cold as the marble floors of the Dhanraj mansion. Forced to smile at family members and cameras and pretend there's nothing wrong with her marriage, Sheetal begins to discover that the family she married into harbors secrets, lies and deceptions powerful enough to tear apart her world. With no one to rely on and no escape, Sheetal must ally with her husband in an attempt to protect her infant son from the tyranny of his family.sion.
Download or read book 2 Methyl 3 hydroxypyridine 5 carboxylic Acid Oxygenase written by Pimchai Chaiyen and published by . This book was released on 1997 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book I Am 9 and Magical written by podMagical Notebooks and published by . This book was released on 2019-09-24 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: I am 9 & Magical Unicorn Journal Happy Birthday 9 Years Old - Unicorn interior journal for kids- 9 Year Old Christmas birthday gift for Girls
Download or read book Lost Children Archive written by Valeria Luiselli and published by Vintage. This book was released on 2020-02-04 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES 10 BEST BOOKS OF THE YEAR • “An epic road trip [that also] captures the unruly intimacies of marriage and parenthood ... This is a novel that daylights our common humanity, and challenges us to reconcile our differences.” —The Washington Post In Valeria Luiselli’s fiercely imaginative follow-up to the American Book Award-winning Tell Me How It Ends, an artist couple set out with their two children on a road trip from New York to Arizona in the heat of summer. As the family travels west, the bonds between them begin to fray: a fracture is growing between the parents, one the children can almost feel beneath their feet. Through ephemera such as songs, maps and a Polaroid camera, the children try to make sense of both their family’s crisis and the larger one engulfing the news: the stories of thousands of kids trying to cross the southwestern border into the United States but getting detained—or lost in the desert along the way. A breath-taking feat of literary virtuosity, Lost Children Archive is timely, compassionate, subtly hilarious, and formally inventive—a powerful, urgent story about what it is to be human in an inhuman world.
Download or read book Agatha H and the Siege of Mechanicsburg written by Phil Foglio and published by Simon and Schuster. This book was released on 2020-03-17 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a time when the Industrial Revolution has become an all-out war, mad science rules the world—with mixed success. In Agatha H and the Siege of Mechanicsburg, Agatha Heterodyne, the last of the Heterodyne family, has returned to her family’s hereditary town with the might of the Wulfenbach Empire hot on her heels. The only thing holding off an outright attack is Gilgamesh Wulfenbach, the heir to the Empire, who has joined Agatha and her friends inside the great artificially intelligent fortress of Castle Heterodyne. Now they must race to repair the mechanisms that once allowed the Castle to defend Mechanicsburg, before the rest of Europa shows up to take all the revenge the mad Heterodynes of the past so richly earned. From the Hugo Award–winning Girl Genius online comics comes this fourth book in the Agatha H. series, and like the previous three books, it will engage you in a unique world of adventure, romance, and mad science!
Download or read book A Starlit Somersault Downhill written by Nancy Willard and published by Little Brown. This book was released on 1993 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having made a plan to spend the winter with Bear napping in a cozy cave, Rabbit finds himself too energetic to sleep and decides to join the world outside.
Download or read book The Longest Winter written by Alex Kershaw and published by Penguin UK. This book was released on 2015-07-30 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cold winter morning in the Ardennes Forest, 1944, and Hitler launches his last and most audacious attack on the unprepared Allies. Standing between the German forces and the desperately regrouping Allies were just eighteen young Americans, hidden in fox holes. In a fierce day-long battle, this small band of soldiers repulsed the German attack three times, inflicting severe casualties and defending a strategically vital hill despite being vastly outnumbered. They surrendered only when they ran out of ammunition. But then the real battle for survival began ... Alex Kershaw's brilliant account draws on the words of the decorated men who fought this heroic action, bringing vividly to life their struggle on the battlefield and later off it - as POWs.
Download or read book The Narrative of John Smith written by Arthur Conan Doyle and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This text has been published from an untitled manuscript that was among the Conan Doyle papers sold at aution in 2004 and acquired by the British Library."--P. [121].
Download or read book Karnali Blues written by Buddhisagar and published by India Penguin Classics. This book was released on 2022-05 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Karnali Blues, by Buddhisagar, is the most widely read Nepali novel to have appeared in the last twenty years. As it recounts the evolution of a father-son relationship-a son's search for approval, a father's small acts of kindness and forgiveness, a son's fears for his father's dignity as his fortunes and faculties begin to fail-the reader is deeply drawn into young Brisha Bahadur's world. His father is kind and idealistic; his mother, though she is kind too, is often frustrated and irascible. The characters in this book are some of the most carefully drawn and authentic in all of Nepali literature. In a backwater district of a country about to undergo radical social, political and cultural change, Brisha's dreams, his games and his mischief, his loves, his hopes and his fears come alive. Translated from the Nepali by Michael Hutt, this highly original piece of work, with the simplicity of its language and its emotional range, holds the power to take your breath away. Its principal themes-the love between a son and his father, the joys and sorrows of childhood, the daily struggle for survival-are universal, and will resonate with readers the world over.
Download or read book Anarchism and Other Essays written by Emma Goldman and published by . This book was released on 1917 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sultana s Dream written by Roquia Sakhawat Hussain and published by Independently Published. This book was released on 2019-05-06 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sultana's Dream is a classic work of Bengali science fiction and one of the first examples of feminist science fiction. This short story was written in 1905 by Rokeya Sakhawat Hussain, a Muslim feminist, writer and social reformer who lived in British India, in what is now Bangladesh. The word sultana here means a female sultan, a Muslim ruler.
