Download or read book The Concept of the Gene in Development and Evolution written by Peter J. Beurton and published by Cambridge University Press. This book was released on 2000-05-29 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.
Download or read book Master Control Genes in Development and Evolution written by Walter J. Gehring and published by Yale University Press. This book was released on 1998-01-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fascinating book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation. Gehring begins his story by looking at the work of the many researchers who laid the foundation for the fields of molecular, cellular, and developmental biology, providing insightful vignettes of past and present investigators. He then describes his laboratory's hunt for the gene that caused odd mutations in the fruitfly--in which, for example, antennae on the head were transformed into legs. He explains that researchers eventually found that the same master control genes that dictate the body plan in flies also pattern human bodies, limbs, hands, heart, and brain. And he illustrates the universality of the genetic control of development by describing the development of the eye; eyes as different as those of humans, squids, and flies, he shows, develop under the same master control gene.
Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams
Download or read book Modularity in Development and Evolution written by Gerhard Schlosser and published by University of Chicago Press. This book was released on 2004-07 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.
Download or read book Shaping Life written by John Maynard Smith and published by Yale University Press. This book was released on 1999-01-01 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past ten years, there has been a revolution in our understanding of developmental biology, as scientists apply the ideas and techniques of genetics and embryology to the processes of development. In this book, John Maynard Smith gives an account of the progress that has been made in this field -- in our knowledge of both the development of individuals and the evolution of the species. Maynard Smith points out that there is a parallel between the developmental changes that convert an egg into an adult and the evolutionary changes converted simple single-celled ancestors into the existing array of multicellular animals and plants. Genetic studies provide the necessary link between development and evolution: natural selection explains how information is incorporated in the genome, and development shows what use is made of it during the development of each individual. Traditionally, two very different views have been held about development. Maynard Smith argues that the differences between them are not so much scientific as ideological -- one can be considered reductionist and the other holistic. But because of advances in the science underpinning both viewpoints, he says, the possibility of a dialogue between them is great, which will be beneficial to the entire discipline.
Download or read book Keywords and Concepts in Evolutionary Developmental Biology written by Brian K. Hall and published by Harvard University Press. This book was released on 2006-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering more than 50 central terms and concepts in entries written by leading experts, this book offers an overview of this new subdiscipline of biology, providing the core insights and ideas that show how embryonic development relates to life-history evolution, adaptation, and responses to and integration with environmental factors.
Download or read book Behaviour Development and Evolution written by Patrick Bateson and published by Open Book Publishers. This book was released on 2017-02-20 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of parents in shaping the characters of their children, the causes of violence and crime, and the roots of personal unhappiness are central to humanity. Like so many fundamental questions about human existence, these issues all relate to behavioural development. In this lucid and accessible book, eminent biologist Professor Sir Patrick Bateson suggests that the nature/nurture dichotomy we often use to think about questions of development in both humans and animals is misleading. Instead, he argues that we should pay attention to whole systems, rather than to simple causes, when trying to understand the complexity of development. In his wide-ranging approach Bateson discusses why so much behaviour appears to be well-designed. He explores issues such as ‘imprinting’ and its importance to the attachment of offspring to their parents; the mutual benefits that characterise communication between parent and offspring; the importance of play in learning how to choose and control the optimal conditions in which to thrive; and the vital function of adaptability in the interplay between development and evolution. Bateson disputes the idea that a simple link can be found between genetics and behaviour. What an individual human or animal does in its life depends on the reciprocal nature of its relationships with the world about it. This knowledge also points to ways in which an animal’s own behaviour can provide the variation that influences the subsequent course of evolution. This has relevance not only for our scientific approaches to the systems of development and evolution, but also on how humans change institutional rules that have become dysfunctional, or design public health measures when mismatches occur between themselves and their environments. It affects how we think about ourselves and our own capacity for change.
Download or read book Embryology Epigenesis and Evolution written by Jason Scott Robert and published by Cambridge University Press. This book was released on 2004-03-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, philosophers of biology have tended to sidestep the problem of development by focusing primarily on evolutionary biology and, more recently, on molecular biology and genetics. Quite often too, development has been misunderstood as simply, or even primarily, a matter of gene activation and regulation. Nowadays a growing number of philosophers of science are focusing their analyses on the complexities of development, and in Embryology, Epigenesis and Evolution Jason Scott Robert explores the nature of development against current trends in biological theory and practice and looks at the interrelations between development and evolution (evo-devo), an area of resurgent biological interest. Clearly written, this book should be of interest to students and professionals in the philosophy of science and the philosophy of biology.
Download or read book Origination of Organismal Form written by Gerd B. Muller and published by MIT Press. This book was released on 2003-01-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.
Download or read book Story Of Genetics Development And Evolution The A Historical Dialogue written by Jekely Gaspar and published by World Scientific. This book was released on 2017-11-24 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique story offers an introductory conversation to genetics, embryology and evolution, taking us on a historical journey of biology through the ages. Using a series of dialogues between the Greek philosopher Democritus and his disciple Alkimus, we travel through time visiting eminent scientists throughout the centuries, from Lazzaro Spallanzani and Theodor Boveri to Francis Crick, Max Perutz and Christiane Nüsslein–Volhard. We find ourselves at the intersection of competing theories in biology and witness the progression from the debunking the theory of spontaneous generation to the mapping of the genome. Attention is given not only to the great successes in the field but also to the equally important and exciting failures. Originally published in Hungarian, The Story of Genetics, Development and Evolution provides a historical background to the life sciences, with complex scientific concepts stripped down and explained carefully for academics and anyone interested in going back to the roots and philosophies of scientific progress. Translated from: Jékely G Master, are you awake? A fictitious dialogue on genetics, development and evolution. 2006, Bratislava: Kalligram Contents: PrefaceAt the HarbourAt the MarketPart One: The Mystery (and Sperm) of Life's OriginsDeux Ex MachinaThe World EggSpontaneous Generation and Meat Broth — Lazzaro SpallanzaniTypes and Rhythms of Embryos — Karl Ernst Von BaerCell From a CellThe Feats of the Sea UrchinPart Two: Chromosomes, Mendelian Factors and EvolutionRoasted CaponThe Immortal GermplasmReduction DivisionA London Pigeon Sale — Thomas Henry HuxleyThe Orchard of EvolutionPeas and Minotaur — William BatesonGalton and MendelTwo Sperm, One Ovum — Theodor BoveriPart Three: The Triumph of GenesTrickster Mendelians — Thomas Hunt MorganSex ChromosomesThe Telltale White EyeGenetic MappingPart Four: Forces and ReactionsThe Mathematics of Life — D'arcy Wentworth ThompsonThe Two-Headed NewtZeus's BeardEvolutionary SynthesisThe Casting Moulds of Genes — Hermann Joseph MullerFronts On the Wings of a Moth — Alfred KühnThe Birth of PatternsPart Five: The Atoms of LifeHormones in Larva BloodOne Gene, One Enzyme — George Wells BeadleThe Protein-GenesThe Principle of Transformation — Oswald Theodore AveryThe Triple Helix — Linus PaulingDNA with AmbrosiaPart Six: Codes and LinksThe Central Dogma — Francis CrickThe Diamond Code of ProteinsThe Genetic CodeA Molecular Lung — Max Ferdinand PerutzSugar-Consuming Bacteria — Jacques MonodPart Seven: Genes in the MortarEpigenesis and Genetics — Conrad Hal WaddingtonA Recipe for Making Mice — Sydney BrennerThe Wiring of a Worm's BrainRecombinant DNAStriped Embryos — Christiane Nüsslein-VolhardOur Worm Ancestors — Detlev ArendtThe Age of Genomics — Eugene KooninPart Eight: Beyond GenesPostcard to ThraceThe Cedar Forest of AbderaThe Philosophy of Biology — Ernst MayrThe Genetics of the BiosphereBiscuits Baked in AshOn the Island of Bensalem — Pál Nagy-Juhász
Download or read book Epigenetics written by Benedikt Hallgrimsson Ph.D. and published by Univ of California Press. This book was released on 2011-04-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.
Download or read book Genes in Development written by Eva M. Neumann-Held and published by Duke University Press. This book was released on 2006-01-27 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf
Download or read book Genes and Evolution written by and published by Academic Press. This book was released on 2016-06-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue. Covers the area of genes and evolution Contains invaluable contributions from an international board of authors Provides a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes and epithelial tissue
Download or read book Developmental Plasticity and Evolution written by Mary Jane West-Eberhard and published by Oxford University Press. This book was released on 2003-03-13 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive synthesis on development and evolution: it applies to all aspects of development, at all levels of organization and in all organisms, taking advantage of modern findings on behavior, genetics, endocrinology, molecular biology, evolutionary theory and phylogenetics to show the connections between developmental mechanisms and evolutionary change. This book solves key problems that have impeded a definitive synthesis in the past. It uses new concepts and specific examples to show how to relate environmentally sensitive development to the genetic theory of adaptive evolution and to explain major patterns of change. In this book development includes not only embryology and the ontogeny of morphology, sometimes portrayed inadequately as governed by "regulatory genes," but also behavioral development and physiological adaptation, where plasticity is mediated by genetically complex mechanisms like hormones and learning. The book shows how the universal qualities of phenotypes--modular organization and plasticity--facilitate both integration and change. Here you will learn why it is wrong to describe organisms as genetically programmed; why environmental induction is likely to be more important in evolution than random mutation; and why it is crucial to consider both selection and developmental mechanism in explanations of adaptive evolution. This book satisfies the need for a truly general book on development, plasticity and evolution that applies to living organisms in all of their life stages and environments. Using an immense compendium of examples on many kinds of organisms, from viruses and bacteria to higher plants and animals, it shows how the phenotype is reorganized during evolution to produce novelties, and how alternative phenotypes occupy a pivotal role as a phase of evolution that fosters diversification and speeds change. The arguments of this book call for a new view of the major themes of evolutionary biology, as shown in chapters on gradualism, homology, environmental induction, speciation, radiation, macroevolution, punctuation, and the maintenance of sex. No other treatment of development and evolution since Darwin's offers such a comprehensive and critical discussion of the relevant issues. Developmental Plasticity and Evolution is designed for biologists interested in the development and evolution of behavior, life-history patterns, ecology, physiology, morphology and speciation. It will also appeal to evolutionary paleontologists, anthropologists, psychologists, and teachers of general biology.
Download or read book The Shape of Life written by Rudolf A. Raff and published by University of Chicago Press. This book was released on 2012-12-14 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rudolf Raff is recognized as a pioneer in evolutionary developmental biology. In their 1983 book, Embryos, Genes, and Evolution, Raff and co-author Thomas Kaufman proposed a synthesis of developmental and evolutionary biology. In The Shape of Life, Raff analyzes the rise of this new experimental discipline and lays out new research questions, hypotheses, and approaches to guide its development. Raff uses the evolution of animal body plans to exemplify the interplay between developmental mechanisms and evolutionary patterns. Animal body plans emerged half a billion years ago. Evolution within these body plans during this span of time has resulted in the tremendous diversity of living animal forms. Raff argues for an integrated approach to the study of the intertwined roles of development and evolution involving phylogenetic, comparative, and functional biology. This new synthesis will interest not only scientists working in these areas, but also paleontologists, zoologists, morphologists, molecular biologists, and geneticists.
Download or read book Modularity in Development and Evolution written by Gerhard Schlosser and published by University of Chicago Press. This book was released on 2004-07 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.
Download or read book Keywords And Concepts In Evolutionary Developmental Biology written by Manorma Singh and published by Discovery Publishing House. This book was released on 2007 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Sting Journalism: Introduction, Forms and Features, Sting Journalism: Ethics, Methods and Hidden Cameras, Sting Operations: Current Perspective, Famous Investigative Journalists and Scandals, Sting Operations in Indian Perspectives.
