Download or read book The Complex Interplay Between Gut Brain Gut Liver and Liver Brain Axes written by Cristina Stasi and published by Academic Press. This book was released on 2021-04-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome. - Provides current and wide-ranging knowledge in the field of gastrointestinal, liver, and brain interactions - Resolves important clinical issues concerning gut, liver, and brain interactions - Demonstrates advances in the understanding of the pathophysiology of gastrointestinal and liver diseases

Download or read book Gut brain Connection Myth Or Reality Role Of The Microbiome In Health And Diseases written by Adrien A Eshraghi and published by World Scientific. This book was released on 2021-11-03 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the recent advancements in understanding the gut-brain interaction as well as gut microbiome and how this interaction plays a vital role in human health and disease are discussed. Each chapter gives an analysis of questions, research directions, and methods within the field of gut-brain axis. The readers will benefit from the latest knowledge about our understanding about how gut-brain axis and modulation of gut microbiome determines predisposition to neurological disorders. The multidisciplinary book is essential reading for anyone interested in the field of gut-brain axis and gut microbiome: from undergraduates to graduate students as well as scientists and physicians having an interest in the new exciting field of gut microbiome and its relationship with brain function.

Download or read book Microbial Endocrinology written by Mark Lyte and published by Springer Science & Business Media. This book was released on 2010-04-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.

Download or read book Microbial Endocrinology The Microbiota Gut Brain Axis in Health and Disease written by Mark Lyte and published by Springer. This book was released on 2014-07-05 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Download or read book Bile Acids and Their Receptors written by Stefano Fiorucci and published by Springer Nature. This book was released on 2019-09-03 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.

Download or read book The Gut Brain Axis written by Niall Hyland and published by Academic Press. This book was released on 2016-05-13 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. - Focuses on specific areas in which the microbiota has been implicated in gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior - Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

Download or read book Brain and Organ Communication written by Charu Mahajan and published by Elsevier. This book was released on 2024-10-11 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain and Organ Communication: Effects of Crosstalk on Neurophysiology examines the intricate relationship between the brain and other organ systems within the body. With an emphasis on homeostasis of these systems, this book also explores how various systems are related and affected by the brain injury or organ damage from a neurophysiological standpoint. This book will be most useful to researchers in neuroscience and graduate students studying neurophysiology. Those with an interest in endocrinology and clinicians in various branches of neuroscience and physiology will also find this book of interest. - Examines cross talk between the brain and major organ systems - Explores multiple organs, including heart, lungs, kidneys, gut, and more - Identifies how this communication affects neurophysiology - Provides management strategies for injuries to the brain and organs

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Download or read book The Microbiome and the Brain written by David Perlmutter and published by CRC Press. This book was released on 2019-12-06 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

Download or read book The Interplay of Microbiome and Immune Response in Health and Diseases written by Gwendolyn Barcel´o-Coblijn and published by MDPI. This book was released on 2019-11-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: [Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]

Download or read book Brain Gut Interactions written by Yvette Tache and published by CRC Press. This book was released on 1991-02-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain-Gut Interactions serves as a reference source and stimulus for expanded research efforts aimed at unravelling the pathophysiology of brain-gut interactions. Within the general framework of brain-gut interactions, it covers the various areas in which this growing interdisciplinary field has evolved. Topics discussed in this volume include the topography and morphology of afferent and efferent connections between the gut and the medulla and hypothalamic nuclei, the role of afferent and efferent pathways in the regulation of gastrointestinal function, the brain's regulation of gastrointestinal secretory and motor function, and the function of peripheral and central cholecystokinin in the mechanisms of satiety. The final section of this book focuses on topics such as stress, emesis, visceral pain, and brain-related disorders of the intestine based on experimental and clinical data. Students and investigators working with brain-gut interactions, gastroenterologists, psychologists, and psychiatrists will find this book to be an essential reference resource.

Download or read book The Mind Gut Connection written by Emeran Mayer and published by HarperCollins. This book was released on 2018-06-05 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutting-edge neuroscience combines with the latest discoveries on the human microbiome to inform this practical guide that proves once and for all the inextricable, biological link between mind and body. We have all experienced the connection between our mind and our gut—the decision we made because it “felt right;” the butterflies in our stomach before a big meeting; the anxious stomach rumbling when we’re stressed out. While the dialogue between the gut and the brain has been recognized by ancient healing traditions, including Aryuvedic and Chinese medicine, Western medicine has failed to appreciate the complexity of how the brain, gut, and more recently, the microbiome—the microorganisms that live inside us—communicate with one another. In The Mind-Gut Connection, Dr. Emeran Mayer, Executive Director of the UCLA Center for Neurobiology of Stress, offers a revolutionary look at this developing science, teaching us how to harness the power of the mind-gut connection to take charge of our health. The Mind-Gut Connection, shows how to keep the communication brain-gut communication clear and balanced to: • Heal the gut by focusing on a plant-based diet • Balance the microbiome by consuming fermented foods and probiotics, fasting, and cutting out sugar and processed foods • Promote weight loss by detoxifying and creating a healthy digestion and maximum nutrient absorption • Boost immunity and prevent the onset of neurological diseases such as Parkinson’s and Alzheimer’s • Generate a happier mindset and reduce fatigue, moodiness, anxiety, and depression • Prevent and heal GI disorders such as leaky gut syndrome; food sensitivities and allergies; and IBS; as well as digestive discomfort such as heartburn and bloating • And much more. Supplemental enhancement PDF accompanies the audiobook.

Download or read book Relationships Among the Brain the Digestive System and Eating Behavior written by Institute of Medicine and published by National Academies Press. This book was released on 2015-02-27 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 9-10, 2014, the Institute of Medicine's Food Forum hosted a public workshop to explore emerging and rapidly developing research on relationships among the brain, the digestive system, and eating behavior. Drawing on expertise from the fields of nutrition and food science, animal and human physiology and behavior, and psychology and psychiatry as well as related fields, the purpose of the workshop was to (1) review current knowledge on the relationship between the brain and eating behavior, explore the interaction between the brain and the digestive system, and consider what is known about the brain's role in eating patterns and consumer choice; (2) evaluate current methods used to determine the impact of food on brain activity and eating behavior; and (3) identify gaps in knowledge and articulate a theoretical framework for future research. Relationships among the Brain, the Digestive System, and Eating Behavior summarizes the presentations and discussion of the workshop.

Download or read book The Gut Microbiome in Health and Disease written by Dirk Haller and published by Springer. This book was released on 2018-07-27 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Download or read book Geriatric Gastroenterology written by C. S. Pitchumoni and published by Springer Science & Business Media. This book was released on 2012-07-26 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Download or read book Modernity in Health and Disease Diagnosis The Account from STEM Women written by Eucharia Oluchi Nwaichi and published by Springer Nature. This book was released on 2023-10-09 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers contributions highlighting the role of women in science, with a focus on health and disease. Women have contributed in no small way to the wealth of knowledge and discoveries in various aspects of health. The 21st century has been dubbed the "Knowledge Economy" due to a substantial increase in the accessibility of information, leading individuals to become more knowledgeable and well-rounded. Given the fact that irrespective of the field of study, knowledge eventually decays, more women in the 21st century have been at the forefront extending the frontiers of knowledge in the field of STEMM (Science Technology Engineering Mathematics Medicine) - engaging in rigorous research and making significant contributions in the field. Letting their voices heard through their well-researched published studies is a significant way of encouraging other upcoming women scientist and bringing advances in disease diagnosis to achieve SDG3. The contributions in this book aim to increase visibility of women in the field of science and to serve as a source of inspiration to everyone.

Download or read book Liver Cirrhosis and Its Complications Advances in Diagnosis and Management written by Ran Wang and published by BoD – Books on Demand. This book was released on 2024-07-24 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver cirrhosis, the final stage of various chronic liver diseases, poses significant health challenges and carries a severe prognosis. This book provides a comprehensive review of the advancements in the diagnosis and management of liver cirrhosis and its complications. Spanning six chapters, this book delves into critical areas including diagnostic approaches and therapeutic strategies for cirrhosis, transarterial radioembolization (TARE) for hepatocellular carcinoma, the pathology of hepatic encephalopathy, and clinical applications of non-selective beta blockers (NSBBs) in cirrhosis management. Bringing together clinical and pathological perspectives, this book features contributions from esteemed authors worldwide. This multidisciplinary approach ensures a thorough understanding of the progress in diagnosing and managing cirrhosis and its complications. This book is designed to offer healthcare professionals, researchers, and students fresh insights and innovative approaches, aiming to enhance diagnostic and therapeutic practices for liver cirrhosis.